Cholesterol level symptoms and conditions

I am a 37 year old man who weighed approximately 188lbs when I prescribed 20mg of Lipitor and fish oil to combat my high triglycerides(437) and my high total cholesterol(212) in August of 2009. I have a high stress job and was experiencing occasional chest pain and heart palpitations. In addition, I have psoriasis and psoriasis arthritis and take Enbrel injections weekly. Prior to taking Lipitor, I had normal liver function tests.

At the same time that I began the fish oil and Lipitor, I began to change my eating habits and began a regular exercise routine. I began to feel better and lose weight. I was enthused about my progress. I took my Lipitor at night, however, I found it difficult to get up in the mornings and I was a little more tired than normal.

Roughly 3 months after beginning Lipitor, I developed a condition of EXTREME thirst. Blood tests from my doctor revealed elevated Liver Levels. His first inclination was that it was Lipitor so I stopped taking it ASAP. A subsequent test a week later indicated little improvement in my liver tests. My doctor suggested we give it two more weeks to test it. I just got my tests back and they actually increased!(ALT 197, AST 90, ALP 571).

My cardiologist does not have anything to suggest other than the possibility of a fatty liver, gall stones, or liver disease. His recommendation was that I get an ultrasound next week of my liver and meet with a GI doctor.

My excessive thirst and fatigue continues. I am not jaundiced but I do frequently experience dark urine. I weigh myself every morning and my weight is now down to 174. I seem to be losing very gradual weight now though my eating habits have returned to my old routine. This worries me. I am now worried that this drug triggered something terrible in my system. Does anyone have any advice?

My total cholesterol was 220 and LDL was 157; I started taking 40mg last week and within 2 days I just felt horrible. I felt weird and yuck in my stomach. There was a fog in my head and 2 days ago I was so dizzy I was almost falling over; I had to catch myself with the walls and doors. The next day, yesterday, I started having higher blood pressure and racing pulse with heart palpitations every 45 seconds or so, which makes me breathe deep often. I have felt pain in the back, arms, neck, and hips. I have also had weight gain and stomach irritability. Last night was the first night I did not take my medicine and even though I don't feel all that better I will see how it goes. I fought taking this medicine for over a year now and since my cholesterol went up I figured I'd try it in hopes my level would drop, but I can't handle this, I'm only 38!

Started taking the Zocor generic Simvistatin just 2 days ago. My legs hurt so bad that I can not sleep. My right knee is swollen to the point I have very limited range of motion and can barely walk up stairs. It is after midnight and I can't sleep. Also having some angina and my little toe on my right foot is somewhat numb. I will be contacting my physician about this tomorrow. My cholesterol was 105 and this doesn't seem to be worth it to me!

I have not had good experiences with various statin drugs through the years. I was on Zocor a few years ago. I suffered from a tripping gait at times (seemed as if the bottom of the toe area would stick to the sidewalk and I felt as if I was going head over heels and balance issues), so much so that I was referred to a neurologist. My internist poo-pooed my symptoms at the time until I mentioned the formation of cataracts. That did it. Zocor stopped. On to Crestor. Crestor was briefly tolerated until I was walking up four flights of stairs. While on the second flight, my legs literally locked. I could not raise my legs (thigh muscles had tightened so badly, that I had to stop, regroup, and start again. Next course after a brief respite, Lipitor. I am taking between 5 and 10 mg. as tolerated.

I have had issues with Lipitor as well, despite the 'pediatric' dose. I have felt occasional ankle tweaks, and most recently over this past weekend, upon going down a flight of stairs, my left knee buckled. Thank goodness I did not fall, but the weakness was there for the day. I have not taken Lipitor since last Friday night. My cholesterol level (off the statins) had reached a high of 357. As of the last testing (my first after being started on Lipitor), it was 255 - my LDL was 137. I know that if I stop the medication that the numbers will start to rise. This yo-yo effect is very frustrating but my overall well-being is of my utmost concern. Both parents had heart disease. My father passed away at 63 years of age (heart attack, recuperation, then massive heart attack 22 months later), and my mother had angina pectoris, bypass surgery and recurrence of blockages, only to die from multiple myeloma at the age of 89. My newest symptom is pain in the right side, outer portion of the rib cage area. This started two days ago. I had this when I was on Welchol as well.

It appears to be, not quite all the facts in yet, but my cardiologist put me on a Lipitor hiatis to see if some of my arrhythmia issues, dizziness and light headedness may be associated with Lipitor.
After just 4 days, I am feeling pretty good! Could be placebo? I don't think so.
After being taken from work in an ambulance to the hospital and experiencing 48 hours worth of testing for a possible coronary, I asked my doctor to examine the possibility of Lipitor causing the symptoms.
I do not have a family history of heart disease. I eat well and am a moderate exerciser. When I was bumped up from 20 mg. to 40 mg. around 6 months ago, my symptoms started.
I have to decide now how much of an elevated cholesterol level I am willing to "live" with. My cardiologist said if it turns out to be the Lipitor, we'll try Zocor and maybe get a higher cholesterol level on my labs, but that's okay. How low does the low need to be??

I am a 61 year old mail. Two years ago I suffered chest pain resulting in the fitting of two stents was placed on Lipitor and had the usual liver function test which proved normal. Initially I was put on a low dose but as my cholesterol level did not improve eventually I was placed on 80mg which is the highest dose and this did lower my cholesterol level to a satisfactory level. A few months ago I had severe unexplained back pain which I thought might be due to the statin and when I stopped taking it, very quickly the pain went. I have restarted the medication for about 6 weeks now and in the last few days have had intense pain in my lower legs, hips and lumbar region. I have decided now to stop taking the drug and will be seeing my doctor shortly. Although I am taking other medication (amlodipine, perindopril and bisoprolol) for blood pressure I feel quite sure that my intolerable pain is due to the statin.

I have been on Lipitor for almost 5 years. I started with a low dose of 10mg for 3 years but my cholesterol did not come down significantly enough so the dose was increased to 20mgs two years ago. I have noticed my hair thinning almost immediately after being put on Lipitor but when the dose was increased the hair started falling out where now it is noticeable, at the front along the hairline, on top and at temples. It has become another problem, at this point, like having high cholesterol. It seems to be happening now at an accelerated rate and my scalp is visible from my hairline 3 inches back. Styling is now impossible without coming the hair all the way forward from the crown, what's left of it. I had no idea hair loss was a symptom of Lipitor until I thought about when it started and the fact I take no other medications. There is no history of this type of hair loss in my family. The Lipitor brought my cholesterol level down to preferred levels but if I stay on it much longer I will be bald on the top and sides of my head. I'm worried it won't grow back.

Except for having high cholesterol (310), I'm a 29 yr old healthy active female, very petite and weigh 98lbs. My mother has had a quadruple bypass and 4 stents at the age of 54, high cholesterol is just hereditary in my family. My doctor put me on 40 mg of zocor. The first week taking zocor I started feeling strange, a little soar here and there and very tired at times, also I have become very forgetful. It's been almost 2 months now and I have severe pain in my legs. First it was the right leg and now both legs, the pain starts at my lower back all the way down to my cav. I have a burning painful feeling sometimes numbing feeling, its driving me crazy!!!! I can't stand for too long cause I feel tons of pressure on my lower back pushing down my legs, It feels like my sciatic nerve. I went to my doctor and he said he is 95% sure that this is from the zocor medication, he told me to stop it right away. This is my first day without it, I know I need to do something to prevent what happen to my mother, I'm on a strict healthy diet, staying away from all fatty cholesterol filled foods, but there has to be a better way then taking statin drugs! If anyone has some ideas of what kind of alternative meds I can take, please help.

I've been on Simvastatin 40 mg for about eight months now. Cholesterol levels dropped significantly. But man have I been hating life! Joint pain mainly in the legs. Beginning to walk like an old man and I'm only 62. Also more pain in my back than ever before! I talked to my doctor, who suggested I get off them for 6 weeks. I did, and I feel like a million bucks. I've got to get back hold of him to find out what he recommends? Probably some other pill!!! Just today I was talking with my pharmacist, and I told him my symptoms. He said the muscle deterioration could actually lead to death. I don't think I'll ever go back on them. I'm going to try and watch the old diet and get more exercise. Hope this helped someone? Good Luck!!

Have been on simvastatin on and off for 15 months now. First of all 10mg came off for a while - cholesterol level up to 7.6 again so was put on 40mg. Very nauseous and came off the 40mg. Went back on to 10mg in Nov. and since then no nausea at all. At present I am getting terrible pain when laying down in my right leg from my hip into my buttock right down to my foot. It is similar to cramp in leg but it lasts sometimes for a couple of hours. Cramp usually disappears in a few minutes but it is the same sort of sensation. Also needle-like pains in my hand and foot. Above symptoms only since going onto Simvastatin. Would be interested in any others have these symptoms too. Trouble is damned if you take them and damned if you dont. Current research does show however that there is no benefit to women over 60 taking these wretched pills - everybody reading this should try and get or borrow the book by Dr Malcolm Kendrick entitled The Great Cholesterol Con (Dundee UK GP) written in 2008 who also is of this opinion. I am not advising not to take Simvastatin but please do research and read this book and reach your own decisions.

I am only 42 years old and have been on zocor for the past 30 months. I've had mild tingling in my feet and achy joints along with slightly elevated liver enzymes and fatigue since then. Ever since my doctor increased the zocor to 80 mg per day ( because although my cholesterol level is normal, my triglycerides are still very high) , I feel like I am 100 years old! All my joints ache so bad and my feet and hands alternately tingle or feel very cold! I am also having trouble focusing when I look from something close up to something far away! I am also clumsier and more forgetful. Could these symptoms be caused by coenzyme-Q deficiency?

The only thing that I have experienced with Tricor is passing gas. And I don't mean now and then, I am talking about the competitive level for some farting contest.
But does it do what it is supposed to? So far, nope.....But then beside the 145mg Tricor I am also on Zocor 40 mg and even with that combo, I am still over 300 Cholesterol, Triglycerides at 1200+.
This is kind of a last ditch effort as I have been on all of the strong Cholesterol drugs. Doctors have been alarmed at my 535 cholesterol level and the 3265 triglycerides - as for HDL/LDL who knows where thats at.
Now, everyone say WOW! then I tell you I have been like this for over 15 years. From Omega3, to extreme high doses of Niacin (the kind that makes you flushed badly), Lipitor, Crestor, and others with some that I took multiple pills - Nothing touches me. (Now 9 different drugs and nothing)
Sugar levels under 120 avg., BP 120/72 or less. As for Muscles, no problem. My only real complaint is the farts 24/7. Yes, even in my sleep.

I was 50 and the doctor prescribed lipitor 10mg since my cholesterol had doubled in the past twelve months to 300. I took it for four months and began to have pain in one leg just below the knee. I had talked to a woman about 65 years old once who was walking on the sides of her feet and I had asked her what medical problem she had. She explained that her Lipitor had caused this terrible pain. You would think that I would have refused to take this drug. You see the doctor had already prescribed a very large dose of fish oil per day and the cholesterol had not fallen. However, I began taking it. About two weeks before my enzyme checkup I began to notice the pain in the leg just below my knee and I stopped taking the Lipitor. I expected the pain to subside, but it did not. My cholesterol level had risen and my doctor asked me if I was still taking the Lipitor. I explained that I had been of it for about two weeks. The doctor insisted that the pain probably wasn't associated with the Lipitor. The reason being my enzyme level was within the range of acceptable. I began taking it again. The doctor wanted to have another test within four weeks to check enzyme levels again. This time the enzyme levels were borderline high. So the doc recommended stopping the Lipitor for a while and then another enzyme level check. You see, my body was telling me something. The only new factor in my medications other than blood pressure was the Lipitor. It has been about three weeks since I stopped the Lipitor, yet I am continuing with even more pain in tops of feet and above one knee a know seems to have appeared. It is sore and feels like it is bruised. I am not a doctor, but I had done some investigating Lipitor on the internet and read that in some patients the Lipitor actually causes small to large fissures in the arteries of the heart. Also, the muscles begin to attack themselves, thus the pain and atrophy. I am going to start taking flax oil. One cardiologist reported that he two cases a week of heart attacks due to Lipitor. He was enraged that Lipitor is still being prescribed and manufactured. I just hope it doesn't take years to regain my original self without pain. I am an active person who likes to work outside, garden, snow-ski, and anything else I want to do. I am trying to search for a detox program for Lipitor overdose, not that I have overdosed. According to my body's signals, I have overdosed on a toxic drug. I pray that returning to normal won't take as long as I have heard some people say it has taken them. Please try some other alternative to Lipitor and the other debilitating statin drugs. I will have to start an exercise program, even though I have put it off for years. I hope my laziness about my physical fitness hasn't crippled me for life. I am 20 lbs overweight and never took it seriously. I hope others will discontinue to take this life-threatening and debilitating drug!!!!!!!!!!1

Hi-I am a 59 year old female have been taking 20mg Simvastatin for 3 months for a cholesterol level of 238 and have noticed significant symptoms that cannot be from any other origin than this medication-dry skin, change of hair texture, psoriasis and bulging in thumb joints, stomach flu, shoulder pain and tingling in hands, vision problems. I am a healthy flight attendant except for all these things that have happened in the last 3 MONTHS!!! I am seeing my doctor tomorrow to discuss a change. I want to take a natural medication to lower my cholesterol.

Hi, I am a 45 year old male with high cholesterol. prescribed 20mg. of Lipitor to control it. Am having a strange twitching muscle in my right calf since I started the meds. Forearms hurt, trouble sleeping, twitching in my sleep, apparently, tiredness. I'm worried about going off it. My dad died of a heart attack. Would it hurt to try going off it for about 3 months?

PLEASE HELP! My father, age 74, was on lipitor for a year or so and then was switched to zocor a few weeks ago to help control his cholestorol. In the past week, the tightening he experienced in his leg, while on lipitor, has become debilitating leg pain now while he is on Zocor. Ultrasounds have ruled out a blood clot. He has no pain when he sits, but he describes the pain has his calf wanting to explode when he stands and he cannot walk with out the help of a cain. The pain radiates from his leg up to his hip.

His cardiologist has taken him off the zocor for a few weeks to see if there is an improvement. It has been 3 days and he feels a bit of relief. SO here is the million dollar question: His labs indicate his cholestorol is normal now, most likely thanks to the statins.....can anyone suggest another form of meds that will help regulate his cholestorol....say COeq10 and fish oil? Any help is SO appreciated!!! Thanks to each of you for your posts. It is so comforting for my dad to know he isn't developing a new issue and that it can be resolved with the removal of zocor!

I have been on 20 mg Lipitor for years, and as I also have Rheumatoid Arthritis, all my symptoms have been blamed on that. I have been diagnosed with Fibromyalgia and put on Lyrica because of the muscle aches and depression. My lower back, hurt in a car accident when I was 17 years old, had gotten so much worse that I had 12 steroid shots in my lower spine a couple of years ago. They didn't help my back at all, but my blood sugar went from normal to diabetic levels, and I am now on Byetta to try to lower it.
I am a 56 year old woman who was the math specialist in a school district until last December when I had to retire early. My back pain was so severe that I could no longer go from school to school carting materials. I could barely make it from the parking lot to my office. Mentally I was not ready to retire, but physically, I was (and am) a wreck. I have severe muscle pain in my shoulders, sometimes one or the other, but always present. I have tingling in my right hand, especially in my fingertips, and have trouble gripping and drop things easily. In the last few months the pain in my right thigh and calf has gotten unbearable. I thought at first it was sciatica, but I have had sciatica before, and this isn't the same, although there is tingling, burning , but the pins and needles is so deep in the muscles I have just sat and cried, or wanted to scream. I have wished I could just cut my leg off. And...I am on some pretty heavy duty pain killers for the RA: a small dose of prednisone plus Enbrel, Methotrexate, and Vicodin, and this pain is cutting right through all these meds. I get severe headaches, I went off Lipitor for 5 days and seemed a little better, but then went back on, and it came back.
Since I no longer work, I sleep longer, am exhausted ALL the time, have terrible mental fog, am clumsy, cannot stand for more than a minute or so without wanting to scream, cannot walk more than a few yards...just getting to the car is an ordeal. I tell people that I can only shop in shoe stores and furniture stores...the only stores with places to sit down.
I no longer cook or clean, cannot play with my granddaughter, even holding a book to read can be too much, and I love reading. I feel I am just dying bit by bit as I lose parts of myself.
My doctor is really into lowering cholesterol, and has put me on Zetia in the past few months...and it has been in this time that the pain in my leg has gotten unbearable. He wants my cholesterol to be between 50-60, and has said that the Zetia along with the Lipitor will do that. Is this normal or in any way reasonable??? I am having a full blood workup done tomorrow morning, and I want to go off the Lipitor starting the day after.
I came across this web site tonight while looking up Lipitor side effects, and I am shocked. I have so many of these symptoms, and there are so many I had no knowledge of at all. I knew about the muscle aches, but that's all. I hope someone can help me with what supplements and vitamins I should be taking. I started taking CoQ10 a month or so ago. What else should I be taking for my health? I know vitamin C and fish oil, but don't know how much or anything else. Right now I am just stunned with the thought that all of these problems that have left me unhappily retired, exhausted and in constant pain can all be caused from a drug I have been taking to help me be healthier.

hi there i have been on simvastatin about a year now and have felt so ill since taking them i am now due to have several blood test to see what they can find " as i suffer with nausea, pains in my legs and body /and terrible depression and i cant remember me feeling like this before i started taking these tablets i really don't feel like me no more / and i can easily sit down and cry because off feeling like i do / now i have been told to take double dose because my cholesterol is higher / i have spoke to others of these tablets and they have had same reaction so i have decided on my own thoughts to stop i will tell my doctor.and i am hoping i will get back to my old self i will try and keep my cholesterol in control and i think its well worth a try than to have all these side affects B.

I recently lost about 25 lbs and decided after about 8 years of 10 mg of lipitor, to go off of it, cold turkey. I consulted both my MD and my pharmacist about whether or not I should wean, and both declined.

I now feel that my sweats, hot flashes are out of control. I am so hot and tired. I feel as though I cannot do the daily functions that I am responsible for.

I truly had NO side effects that I know of ON the drug. I just figured I'd see how I do now that I lost some weight. I wonder if going OFF lipitor is dangerous?

If anyone knows, please reply!

Thank you!

* Completely sunburned after 30 minutes in the sun
* Have to get up at least once a night to urinate (never had before)
* Extreme pain in my feet when I first get up in the morning. (Goes away in 30 seconds) If I feel it when I get up to urinate, I won't feel it later when I normally get up
* Decreased sex drive
* Cholesterol decrease from 310 to 147

Afraid these side effects are just the beginning

Over 6 years ago, the following Petition was submitted to the FDA, I would encourage every patient being treated with statins to read it and bring it to the immediate attention of their physician:

CITIZEN PETITION TO CHANGE THE LABELING FOR
ALL STATIN DRUGS (MEVACOR, LESCOL, PRAVACHOL, ZOCOR, LIPITOR, AND ADVICOR) RECOMMENDING USE OF
100-200mg PER DAY OF SUPPLEMENTAL CO-ENZYME Q10 TO REDUCE THE RISK OF STATIN-INDUCED MYOPATHIES (INCLUDING
CARDIOMYOPATHY AND CONGESTIVE HEART FAILURE). http://www.fda.gov/OHRMS/DOCKETS/dailys/02/May02/052902/02p-0244-cp00001-01-vol1.pdf
May 24, 2002
Petitioner:
Dr. Julian M. Whitaker, M.D.

This Petition is based in part on the clinical findings of Dr Peter H. Langsjoen, MD, which he also reported to the FDA:

Statins kill people - lots of people - and they wound many, many more. All patients taking statins become depleted in Coenzyme Q10 (CoQ10), eventually - those patients who start with a relatively low CoQ10 levels (the elderly and patients with heart failure) begin to manifest signs/symptoms of CoQ10 deficiency relatively rapidly - in 6 to 12 months. Younger, healthier people who's only "illness" is the non-illness "hypercholesterolemia" can tolerate statins for several years before getting into trouble with fatigue, muscle weakness and soreness (usually with normal muscle enzyme CPK tests) and most ominously - heart failure. In my practice of 17 years in Tyler, Texas, I have seen a frightening increase in heart failure secondary to statin usage, "statin cardiomyopathy". Over the past five years, statins have become more potent, are being prescribed in higher doses, and are being used with reckless abandon in the elderly and in patients with "normal" cholesterol levels. We are in the midst of a CHF epidemic in the US with a dramatic increase over the past decade. Are we causing this epidemic through our zealous use of statins? In large part I think the answer is yes. We are now in a position to witness the unfolding of the greatest medical tragedy of all time - never before in history has the medical establishment knowingly (Merck & Co., Inc. has two 1990 patents combining CoQ10 with statins to prevent CoQ10 depletion and attendant side effects) created a life threatening nutrient deficiency in millions of otherwise healthy people, only to then sit back with arrogance and horrific irresponsibility and watch to see what happens - as I see two to three new statin cardiomyopathies per week in my practice, I cannot help but view my once great profession with a mixture of sorrow and contempt.

I am 31 year old been on zocor for 8 months. Doctror prescribed it for cholesterol was 230. I have had muscle weakness, pain in shoulder, chronic neck pain,anxiety attacks, hives,and uncontrolled itching,and have been put on meds for depression.I am stopping the medication tomorrow thanks for all the posting very enlighting. Will post again in a few months.

My cholesterol was tested at 220. My doctor prescribed Lipitor 40mg once daily. Initially I felt slightly nausea but continued for eight month. Most recently I have felt stiff neck, sore shoulder, increased nausea, and nervous/anxious symptoms. Yesterday I didn't take my Lipitor and within hours felt remarkably better. This morning I resumed my Lipitor and within one hour began to feel like poorly again. I'm considering stopping Lipitor and living with cholesterol level.

Re: Dosage Confusion- Synthroid

This simple of communicating dosage became confusioning. To prevent confusion synthroid is always discussed in terms of (mcg). That is, micrograms (mcg) vs. milligram (mg).

This is of tremendous value The conversion factor is 1000, for example a dose of Synthroid represented as 0.025mg, would be converted as
.025mg x 1000=25mcg. To fully understand this blogger’s statement feel comfortable to talk with your pharmacist or physician.

I have been reading about the side effects of lipitor for several days now and am scared silly! I have been taking it for nearly 5 years now. My doc warned me about the muscle weakness/pain when I began taking it, but I didn't have any problems and it definitely provided good results for my cholesterol level. During the past several months though, I've begun to have severe symptoms. Actually, looking back, I realize I've had some of these symptoms for awhile but they were so easily attributable to other causes that I didn't pay close enough attention. I am weak to the point of not being able to walk a city block without being tired; my breathing is so labored sometimes just moving around my apartment is a problem. My knees and lower legs are painful, especially after walking. I get frequent, painful spasms in my lower arms and wrists. My speech has become slurred (I sound drunk) and my voice very hoarse - both so much so that people have trouble understanding me. I have trouble concentrating, am forgetful and am often dizzy and light-headed. I take medication for GERD, hypothyroidism, depression and asthma. But in case you think these symptoms could be from one of those (as I did!), I can assure you that I have had multiple tests which determined my thyroid levels are good, my BP is excellent, I have no signs of cardiac disease or diabetes, no sign of any type of stroke, no signs of any type of cancer or blood disease, no sign of pulmonary problems (other than asthma). I stopped taking Lipitor four days ago after consulting my doc. But I got to tell you, I am scared to death that I've been on this drug so long these symptoms won't go away. Any advice or suggestions would be most welcome.