Connective tissue disease symptoms and conditions

I was on levaquin august 2008 for a sinus infection. After about day 5 is was in pain. My joints ached terribly. My knees, my hips, my wrists, elbows and fingers. I have undifferentiated connective tissue disease with lupus like symptoms. I thought that maybe the levaquin made me flare. I stopped taking it on day 5 and after a week felt somewhat better. I am on meds for joint pain for my autoimmune condition but still had the joint pain with the levaquin. The physicians assistant that I saw said joint pain wasn't common. From what I'm reading here it's very common.

I also felt the "hangover" effect as mentioned by the others. Headache, foggy thick, I call it "doughy brain", agitation. I have a connective tissue disease, FMS following trauma from 06 auto accident plus chronic neck and back pain so the pros outweigh the cons. I take a Vicodin 750mg Flexeril and Serax cocktail at night before bed...and sometimes sleep...sucks.

WEIGHT GAIN, NUMBNESS IN FINGERS AND FEET. LET PAIN. I ALREADY HAVE RHEUMATOID ARTHRITIS, MIXED CONNECTIVE TISSUE DISEASE, THYROID DISEASE AND AM MISERABLE ON THIS.

I GAINED 12 POUNDS IN TWO MONTHS. I'M IN A FOG AND CAN'T REMEMBER ANYTHING. HAVE REALLY BAD LEG PAIN TRYING TO EXERCISE.

I THINK THIS DRUG SLOWED MY METABOLISM.

took one dose of avelox at 830pm yesterday and then took one dose of hydrocodone for cough at 1100pm. Woke up 2 hours later with ankle & wrist joint pain, swollen flushed face and upper extremeities, completely bloodshot eyes(no visible whites), fever, chills, neck stiffness, itching on neck,shoulders and arms, general body aches, overall joint stiffness. saw doc today and he said conjunctivitis-prescribed drops, and that it was just the infection I had running it's course. Now my husband does not want me to take this evenings dose. perplexed as I have some underlying connective tissue disease and I am not sure if the joint stuff and redness is just due to being out in the sun yesterday without sunscreen and the aftermath

Has anyone on Lisinopril experienced upper GI problems such as Achalasia, trouble eating, reflux, or getting food 'stuck' in the esophagus?
My wife has lost 50 lbs in a year due to inability to eat from what was initially diagnosed as Achalasia (rare disease that affects the operation of the muscles in the esophagus and/or lower esophageal sphincter at the top of the stomach). However, Botox injections in the LES provided little relief which is not typical for Achalasia patients. She tests negative for Barrett's Syndrome and any form of Connective Tissue Disease (or arthritis).
My MD recently put me on Lisinopril (another horror story); while I was researching the drug, I noticed that it could cause muscle weakness. My wife backtracked the date that she was put on Lisinopril and it coincided with the onset of her GI problems. While monitoring her BP several times a day, she has cut back to 1/2 dose and has shown a marked improvement in the last 10 days. (It is too early to say with certainty that Lisinopril is causing the GI problems.)
Has anyone experienced similar problems?

It's scary in here...lol..Mixed Connective Tissue Disease, Primary Biliary Cirrhosis,Pulmonary Fibrosis, Sjogrens. Yes, it makes you feel better, especially at the beginning when the side effects aren't there. But MAN, does any body else feel like SCREAMING? LOL. I look like an entirely different person. Been on it for one year. Not even a large dose. My weight has just kept on coming. I think there is an alian in my stomach. And I think someone has inflated my upper body with something. Swollen, bloated,uncomfortable, fatigue, weakness, etc,. Do you eat like it's your last meal on earth sometimes????? Like some primative instinct separate from common sense. Some days I feel like it's the end of the world. But we'll make it. All of us.

Been on Prednisone about 6 weeks. I've had muscle fatigue, especially when its hot out (walking through a parking lot on a 100 degree day takes a little longer than I'd like). One thing I haven't seen mentioned here is that I have lost lean body mass. I had been having my body fat tested by a personal trainer (pinch calipers) before and after I started (30 mg/day for lung restriction (62%)/inflamation/collagen vascular disease/immune mediated lung disease/likely Mixed Connective Tissue Disease/autoimmune disorder). After 1 month on prednisone, despite the fact that I have continued to work out (cardio and resistance), I lost 3 lbs of Lean Body Mass. 3 weeks later I had lost another 3 LBM, and gained 1 lb fat mass. I'm glad to have kept my overall weight down, and my circumference measurements haven't gone up, but there is definately a redistribution of fat.

Other side effects moon face, acne, depression, energy swings (up/down). Heart burn, went from 8 hours sleep to 5 1/2 - 6 average, and facial hair growth. The overwhelming hunger (not just being hungary, but eating a full meal and not feeling satiated at all) has subsided for the most part. The drug is not fun. My doctor is now having me start imuran with the hope of lowering/eliminating the prednisone, but imuran has its own side effects.

The hardest part is that the doctors don't know what will work, its guess and check...When the side effects overshaddow the initial symptoms, is it worth it?