Consumers symptoms and conditions

I have been reading all of your Simvastatin experiences with high interest and would like to share my adventures with all of you as well. My story began seven years ago when I was relatively healthy and enjoying life. My doctor prescribed Lipitor for my elevated cholesterol and two months later I found myself in the emergency room after having a severe bout with vertigo for the first time in my life. I have since spent the last seven years fighting this debilitating illness which continues to haunt me after having seen every top neurologist in my area and having taken every neurological test available. It would be as difficult to convince me that I was not somehow "poisoned" by Lipitor as it was for me to convince my doctor.

I was eventually prescribed Simvastatin 40MG and seemed to stabilize for a few years even though my dizziness problems persisted. Suddenly I began experiencing bouts of upset stomach and severe lower abdominal pain. I allowed my doctor to order basically every nasty test known to man in an effort to discover the cause of this new problem, but all have come up negative so far. Eventually I began to experience total exhaustion in the middle of my work day, not to mention the back, neck, and muscle pain that has been described so vividly in this forum. Basically, I have become a 53 year old man who feels much older, has absolutely no energy, and rarely has a day when I can honestly say I feel alive and well.

I am not a doctor and I can't honestly prove that Simvastatin is the cause of all of my problems. However, I do have common sense and after reading all of your thoughtful comments on the subject I would be foolish to at least not suspect that the drug may possibly be making me less healthy and not more healthy. Thank you all for opening my mind to this possibility and I certainly plan on discussing this with my doctor very soon, who may no longer by my doctor should he continue to insist that I take this nasty drug.

I have been on Lipitor for almost 5 years. I started with a low dose of 10mg for 3 years but my cholesterol did not come down significantly enough so the dose was increased to 20mgs two years ago. I have noticed my hair thinning almost immediately after being put on Lipitor but when the dose was increased the hair started falling out where now it is noticeable, at the front along the hairline, on top and at temples. It has become another problem, at this point, like having high cholesterol. It seems to be happening now at an accelerated rate and my scalp is visible from my hairline 3 inches back. Styling is now impossible without coming the hair all the way forward from the crown, what's left of it. I had no idea hair loss was a symptom of Lipitor until I thought about when it started and the fact I take no other medications. There is no history of this type of hair loss in my family. The Lipitor brought my cholesterol level down to preferred levels but if I stay on it much longer I will be bald on the top and sides of my head. I'm worried it won't grow back.

Update..1 week off the simvastatin now. Still not myself, but I am noticing that I have a little more energy. I can go outside again and visit with family and friends. Some days are better than others. I still have terrible pain in my upper right abdomen, and my ankles still really hurt when I walk, right shoulder is still very stiff and sore to move. I hope what ever damage this poison did to my body over the 11 months will get better. I am only 36, and this pill made me feel like all I wanted to do was die! I AM SO MAD at my Dr. Fresh out of med school. I haven't even called for my next appt. yet, I'm worried that I wont be very nice to her at all. How can they give this to people. She never said anything to me about any of these possible side effects. I did a search on FDA and Simvastatin, I can not believe they would allow Doctor's to give this poison, I guess it is all about the money for them, while we the consumers suffer.

I've been on lipitor and other generic forms of it for the last 8 years since the age of 26. I started on 10mg then 20mg and later 40mg. About 4 years ago I started with severe stomach cramps. The pain is so bad that I have to go home in the middle of the day, I can't walk or sit straight the pain is that bad and NOTHING helps. On a scale of 1 to 10 I would probably put this at a 7 or 8. I would also be nauseous and be really tired. I have had countless opinions and tests done and doctors keep telling me it is an "enigma" and there's nothing wrong with me. We've treated it through coeliac diet, exercise, lots of water, but it never helped. About a week ago I stopped drinking my meds by pure chance. I have not had one incidence of stomach ache. My doctor tells me that it's not possible for the lipitor to be the cause. I am sure he's wrong. Has anyone had a similar experience?

well, well, well, I stopped taking Singulair about a month ago after reading bad side effects. Guess what? My medication resistant depression is GONE. I was on Singulair for about 9 yrs....and on EVERY antidepressant there is....I went thru so much ag, and side effects, when it was the Singulair all along! Now to find a NATURAL asthma helper.

May 16 y.o. daughter has chronic sinus infections and sever headaches. They said it was allergies and put her in Allegra D and Singulair. Headaches seemed better with slightly fewer sinus infections. Once I heard about the mood swings and Singulair I took her off. Then the Allegra did not seem to be able to keep up with keeping the sinus infections at bay. We finally figured out that she has a deviated septum and will need surgery. Anyway, we put her back on Singulair so we can get though the season with as few sinus infection until we can schedule surgery around high school and sports. Then we were noticing how her hair has become so thin. She used to have really thick hair and now her pony tail is to thin and small. After doing internet searching, we found out that other people are having this problem with Singulair. I took her off of it 4 days ago and already the shower has less hair in it. You can't tell a teenager that she needs to stay on a medication and lose a ton of hair. I am hoping that her hair will grow back quickly.

I was on Toprol XL for an irregular heart beat. Then I switched to the generic Metoprolol Succinate ER. I had no problems until they started being made by a different manufacturer. Not only did they look entirely different, but they did not treat the symptoms. When I called the manufacturer they said that it was very unlikely there was a problem since they were regulated by the FDA. I recently found out that one manufacturer was cited by the FDA in August of 2008 for failure to comply with regulations. It was brought to their attention by consumer complaints. I went back on the the name brand for a while but when I could no longer afford them, I went back on the generic. I had no problems then but I just went back to get a refill and was told the manufacturer was no longer making the generic and only the name brand was available. The generic was ordered from a different manufacturer and was on back-order, so I had to go back on the name brand. I would like to know what is going on with this drug. why have there been so many complaints when consumers were switched to a different manufacturer and why have at least two manufacturers stopped making it?

I am 34 years old. I am a pharmacy tech. I have asthma and allergies. I have taken singulair pretty much every day since it came out on the market. I've had asthma since i was about 10 years old. I took theophylline as a kid. Steriods on and off especially during times when my allergies are bad. I still use Advair during the fall and spring. Every drug has a side effect. However breathing is pretty good damn thing. Do I have days when I feel low? Yeah. Do I sometimes have nightmares? Yup. Are "natural" products the answer. Not always. The fish oil that some of the posters are touting can also cause GI problems. Some of the natural products contain herbs and other plant derivatives that can be harmful for a child that suffers from allergies. Not proactively treating asthma can be deadly. Some of the parents are suggesting steriods as the answer - those can cause weight gain, growth suppression and can lead to a worsening of asthma.

Singulair has never made me feel like I've wanted to kill myself. I was more depressed and angry as kid when my asthma did not allow me to partipate in normal childhood things. I was sad and hated life when I couldn't keep up with friends at recces because I was having trouble breathing. You have to outweigh the costs with the benefits. I am more irritable when I have asthma flareup then I am on a normal day. For me, I choose to breathe. And singulair has been helping me for almost a decade.

I'm not saying the medication isn't causing these symptoms but maybe there is an underlying cause to your child's depression.

Any drug has a side effect. But without medical research and the medications that come with them - people would still be dying of simple diseases and we wouldn't have vaccinations. As a society, as a whole, we are a culture that looks to someone else to fix things and then blames the people who try to fix it. We need to stop being the "hot McDonald's coffee'" society.

headache,nauseous,leg cramps, pain in my left breast, around heart...now, around each period my breasts hurt, and i have terrible stomach ache, like cramps, which i never had before..i also started having acne on my back and shoulders...but the worst thing is, my room-mate, she was using Yasmin for 9months, died a week ago. she wasn't sick at all.she actually did have a few headaches, and weird stomach ache, but we didn't seem to connect the two...

I got my Mirena fitted 5 weeks ago. After the 1st week I could feel myself starting to become really low, my head began to get ‘foggy’, total lack of motivation and the headache from hell. This peeked at 3 weeks when I became very depressed, snappy, anxious, extreme tiredness, tearful, severe headache and an inability to concentrate – my brain felt it had no depth to focus or absorb anything. I also felt I was standing on the outside, looking in! I had a similar but far milder reaction to the POP so recognized the symptoms immediately.
I went back to the doctor and tearfully explained how I was feeling and how I was convinced it was a reaction to the Mirena. She totally dismissed this and said she felt there was a lot more to it than that and started talking about PN depression. She also said that in the 16 years of fitting the Mirena she had never experienced anyone with these symptoms. I assured her I was not suffering from PND, but in my ‘fragile state’ wasn’t capable of arguing my point and began to wonder if she was actually right, so what a relief to discover this web-site! I also found a great document issued by the New Zealand Medicine and Medical Device Authority, a Government Agency (http://www.medsafe.govt.nz/Consumers/cmi/m/Mirena.htm ) acknowledging that all the side effects I was experiencing were all common occurrences in between 1 and 10 in every 100 patients – it also acknowledges virtually all the other symptoms everyone else is listing and states that ‘These side effects are more common during the first months after insertion’- so why wasn’t my doctor prepared to accept these symptoms when they are officially recognized in other countries? Are the drug company bonuses more important than patient health?

Anyway, 5 weeks on and my mood has lifted, deep down I still feel low, but my normal self is sitting on top of it. I still want to snap at the kids, but I can control the urge to do so! My head is still foggy and I still feel detached from everything, the headache is still there and I still can’t concentrate / absorb anything! My fingers, knees and wrists now get really stiff / sore and the back of my neck aches when I wake every morning. Fortunately, I haven’t had any cramping or much spotting.

I am due to get it checked in 1 weeks time, but have decided to get it out and hopefully get it replaced with a non-hormone coil. Heavy periods seem great compared with how I’m feeling right now!.
I can’t wait to get back to my old self!.

PLEASE Check out what the NEW ZEALAND MEDICINES AND MEDICAL DEVICES SAFTEY AUTHORITY says about MIRENA http://www.medsafe.govt.nz/consumers/cmi/m/mirena.htm SCROLL FURTHER down to the section that says ADVERSE SIDE EFFECTS!!!!!

BTW THIS IS THE MOST DETAILED AND PROBABLY MOST ACCURATE DESCRIPTION OF MIRENA SIDE EFFECTS BY A PROFESSIONAL BODY.

Its a GREAT SHAME that in the US & UK , and in other parts of the world this type information is not available to women :-(

I don't know what is wrong with you people but its like you can't handle anything. I had the mirena put in November last year and yeah ok i had cramping for the first month or so and yeah i had spotting. But unlike some of you fools i knew what the side effects were i read what came in the package which means i knew what to expect before i got it put in. And yeah there are loads of possible side effects but if you read everything and know what could happen you shouldn't complain if something does happen. Not everyone who has the mirena has these things and for people who are considering it i would recommend trying it and after 3 months if it doesn't feel good then get it removed. That especially goes to people that have just had a baby... i mean really in the first 3 months after having a baby who is really seriously interested in sex right away. The reason i am here was to see if there was more information about them now because UNFORTUNATELY i had to have mine removed for an operation. I had a cyst on my fallopian tube which was not mirena related. In fact almost all women get them when they are menstruating but they go away. Unfortunately with me they don't go away and this is the 2nd cyst to be removed in 3 years. I am planning on getting a second mirena inserted next week. Because frankly i find it ideal. And yeah i may have had mood swings on occasion while i had it but come on think about it what woman doesn't have mood swings. So sure you can blame everything on the Mirena but for the most part besides then for the people where the mirena got stuck or moved during the time you had it... its all in your head. And like i said before i would recommend the mirena and if after 3 or 4 months it doesn't suit you then go for something else... but don't dismiss it because some people have too much time on their hands and like to spend it whining over everything on the net. Remember with the Mirena you have a 50/50 chance of having symptoms or not. Take that risk before taking the risk of going on the pill and forgetting to take it or going on depo provera and putting on 20 pounds.

I was on Doxy for a month and a half due to mild acne. For the first month, I felt fine, however when I went to refill, things became awful. Although I did not notice the nausea or tiredness (because I took it before going to bed), I began to feel episodes of dizziness, confusion, inability to concentrate, and anxiety. I continued taking it because I had not been informed that these might be side effects. Eventually I had 2 panic attacks where my legs shook uncontrollably, I felt I could not breath, became really cold and sweaty, had racing thoughts that I might die, and felt incredibly confused. The attacks really scared me to the point where I was afraid of having another one. When I went to the doctor, they ran blood tests, told me everything was alright, diagnosed me with panic disorder, and gave me medication. Even though I told them I was taking this medication, no one ever told me this might be side effects. I have never had any mental problems and am an upbeat, happy person. While taking this, I had severe anxiety and bouts of depression where I felt like crying for no reason. I was afraid to be alone, I was afraid to workout, and afraid to leave the house. I could not study and thought my entire life was spinning out of control. I've been off it for 2 days and am feeling much better. Anxiety has decreased and depressive episodes are also decreasing. There should be better research on these drugs to inform consumers!

My daughter was prescribed Singulair in the spring and it worked wonders.Since her allergies and asthma don't bother her in the summer I took her off for those few months.Since she has been back on the last few months I notice once and awhile an aggression/depression behavior.I thought immediately that it was Singulair causing this but it wasn't everyday it happened.I believe that activity,schedule,and even food in combination with this medicine that was cause this rare effect.It's no news to parents that all of these things can change a persons attitude and behavior.I also believe that Singulair may just make people more sensitive to their true self as my daughter has always been paranoid and has lacked self esteem.I think that it is trial and error as with any medicine.Try it and it may or may not work for you.Taking it off the market would be a disgrace as it has saved many lives.

I've taken Ambien only once or twice with no side effects. My boyfriend however, takes it every night. He goes on ALL night eating binges, consuming almost everything in the kitchen. In the morning, the kitchen is littered with empty peanut butter jars, cracker boxes, cold cut wrappers, ice cream containers, jelly jars, left over take out boxes, etc. etc. This is what he consumers in just one night. This also happens night after night. I've asked him about it, and have had conversations with him while this is all going on. He seems lucid, but has absolutely no memory of his eating in the morning..But this new problem happened just the other night. We had what I thought was really terrific sex..You could have knocked me over when he said he did not have any memory of it what so ever This really scared me, and really got me thinking. He seems very sluggish during the day, without much energy. He has basically stopped going to the gym every morning, and I can see that he's putting much less effort into his very lucrative business. I've mentioned Ambien as a possible cause of these behaviors, but he doesn't seem totally convinced...What else could it be?

My daughter had been on singulair from the time she was 8 yrs old until she was 14. This will sound as if I am a horrible mother but I just thought that she was a raging bitch. Without my knowledge, she stopped taking her Singulair for a few months and she became a different person. She was so sweet and loving. One night she came in my room having an asthma attack and I asked her if she was taking her meds, she admitted that she had stopped taking her singulair and I got on to her and immediately got her prescription refilled. Within a few days of taking the singulair she turned into a raging, screaming emotional wreck, a TOTALLY different person. I feel so bad that for 6 years of her life I put her on medicine that caused her to have screaming, uncontrollable tantrums, and severe mood swings that caused her to be miserable. It does seem to be the only thing that effectively controls her asthma symptoms but the emotional havoc that is causes her and the people around her is not worth the benefits. We have an appt. with her doctor to see what other options we have.

The following article in the WSJ may explain the reason for the significant number of Adverse Reactions to statin drugs.

Why You Can't Tell Where
Your Medication Was Made
April 8, 2008; Page D1- Wall Street Journal
Bananas come with those little stickers listing their country of origin. Why not pharmaceuticals?
That's what some consumers -- and even some physicians -- are asking since the Food and Drug Administration linked the deaths of 19 people to contaminated batches of the blood thinner heparin from China.
*******

I encourage every patient with a bad experience taking statins to contact the FDA (see, July 1, 2008 posting for FDA contact info).

The following article in the WSJ may explain the reason for the significant number of Adverse Reactions to statin drugs.

Why You Can't Tell Where
Your Medication Was Made
April 8, 2008; Page D1- Wall Street Journal
Bananas come with those little stickers listing their country of origin. Why not pharmaceuticals?
That's what some consumers -- and even some physicians -- are asking since the Food and Drug Administration linked the deaths of 19 people to contaminated batches of the blood thinner heparin from China.
******

I encourage every patient with a bad experience taking statins to contact the FDA (see, June 29, 2008 posting for FDA contact info).

I was prescribed Levaquin in Feb./March for 30 days. I have had tremendous pain in my heels since then. I am walking slower as every joint and muscle in my body hurts. I can barely stoop down and it is getting worse. I can not sleep. I thought I was just going through some depression and stress until I started reading about it in the WSJ and now realize I fit many of the symptoms being discussed.
We all need to take some action as this is only going to get worse for everyone.
FDA?????????????????

We are looking for people who can participate in a documentary film to be shot in Los Angeles which focuses on the apparent adverse effects of Levaquin. Specifically, we are looking for people who have experienced cartilage damage or burst and ruptured tendons as a result of using Levaquin. It is especially useful if you have a doctor's opinion that the damage was caused by Levaquin. If you or someone you know would be interested in taking part in this film which will shoot in Los Angeles in mid-June 2008 please email us at ******

MARCH 17TH MY MOTHER WAS A VERY HEALTHY ACTIVE FUN LOVING PERSON AS OF TODAY SHE IS TOTALLY CONFINED TO THE BED. SHE TOOK 4 PILLS OF LEVAQUIN FOR A MINOR CHEST COLD AND GOT A VERY BURNING RASH AND BLISTERS ON HER ARMS NECK AND CHEST AFTER THAT THE SORE THROAT AND EXTREME MUSCLE FATIGUE KICKED IN .HER DR. PUT HER OFF SHE WAS SMART ENOUGH TO QUIT TAKING THE DRUG ON HER OWN ON APRIL 8 SHE WAS HOSPITALIZED WITH THE ABOVE SYMPTOMS WHICH HAVE ULTIMATELY MADE HER UNABLE TO USE HER MUSCLE SHE CAN NOT SWALLOW HAD TO HAVE A PEG TUBE PUT IN SHE HAS NOW BEEN WEENED OFF OF THE 120 MG OF PREDNISONE SHE HAS BEEN ON AND NO END IN SIGHT ON RECOVERY. I HAVE NO MEANS TO TACKLE A DRUG COMPANY BUT I WILL TELL MY STORY AS OFTEN AND AS I CAN. 50 DAYS LATER WE ARE STILL TRYING TO GRASP ALL OF THIS

mirena DOES NOT prevent ovulation!! meaning you will still ovulate, but the sperm and egg cannot implant themselves which in turn will cause a miscarriage!! This is the same for all iud's, For some unknown reason docs will not tell you this, but my doctor did and strongly advises not to use iuds!! You will get pregnant! You may think your having a heavy period but really you could be passing a dead fetus! Sorry to be so blunt, please do research before you choose this method of birth control

My opinion:

After many hours of searching scientific databases, I have so far been unable to find any research that has been done on how Singulair (montelukast) affects the brain and brain function. So far, I have also found no funding opportunities for any researchers to study montelukast and the brain. That does not mean that they don't exist, I just haven't located any as of today. I have been to many sites putting montelukast in the search area.

I personally believe that this is a consumer BEWARE situation. I personally would not take this drug after seeing for myself how little we can find out about how it interacts with brain chemicals. The FDA needs to require drug companies to study how medications affect the entire body not just one area. Human beings aren't just a nose and a pair of lungs. And we can't keep going around to different doctors to try to find a fix for a medication that is screwing up other parts of our bodies.

After learning that some researchers in other countries have found leukoteine receptors in the brain of human beings, I find it possible to believe that everyone who takes this medication that suppresses the function of those receptors are in some way being affected by Singulair whether they know it or not. I would want to know that Singulair was studied carefully to show how it affects the brain and what the long term consequences are for those who take it. Until that is done, I believe that consumers should heed the warnings regarding adverse psychiatric drug reactions and consider all of the potential options for safe and effective treatment of their conditions. If Singulair is the best option, then consumers should be told what the risk are and how to handle them.