Corticosteroids symptoms and conditions

Kenalog destroyed my life! All corticosteroids are dangerous. Almost 4 years now of intolerable suffering. A doctor gave me trigger point injections w/Kenalog and it spread a "hidden" bacteria throughout my body and reactivated dormant viruses (that we ALL have). It shoots down immunity for MONTHS and gives opportunity to bacterias and viruses to disseminate throughout the body. The FDA should ban all corticosteroids. The pain and suffering from a bacteria I didn't even know I had, that was co-existing in my body fine until "set free" was Lyme Disease. Lyme disease is the most insane disease there is, trust me and it is NOT easy to get rid of, especially when your body has been slammed by these immunosuppressants. Also, I was on Ibuprofen for pain, but the doctor never asked if I was on any NSAIDs and the two combined are like a bomb. If this helps anyone ....thank God, because I go on trying to survive.

Just wanted to let everyone know that you can get Intal Inhaler overseas. It is simple the best asthma med I've ever used and it has been around for 30 years. You can ask you doctor for a prescription. I got the 5 mg. I take 2 puffs 4 times a day, but you can take it up to 8 times a day if you need to.

Did the Singulair, Flovent, Flonase and I developed panic attacks, panic disorder, agoraphobia, depression and ulcerative colitis. Slowly got off of all of them and not only am I almost back to my normal self, I can breathe!

I get my Intal Inhaler at Panther Meds, butotherplaces offer it too. It takes about 3 weeks to get as it's coming from overseas. Please note - Europe's drug process is much more severe than ours. The prescribed Intal more than any other asthma medication. They say the corticosteroids should only be used with extreme, uncontrollable asthma due to all of the side effects.

I have been taking prednisone for three years now and I love it. When I am off of it I cannot breath and I get fluid in my lungs and my arthritis comes back and I ache all over. I could not live without it. The only side effects I have is a little weight gain, sweating, and moon face but the side effects are better than the all over acheing and not being able to breath. This drug has been very good to me.

Male 28. Was diagnosed a couple of months ago with Ulcerative Colitis and was prescribed Prednisone. A large dose to start with then tampered off for 4 weeks. The first week I felt great, better than great, fantastic. The only downside was difficulty sleeping. The following 3 weeks, without any exaggeration have been among the worst I have ever experienced. I think the lack of sleep finally caught up with me, so I was constantly tired and generically felt depressed, also knee ache, eye pain, inability to think clearly (quite a problem when you are an Engineer), lacked energy or strength – and the Acne. Never before have I had Acne like this, and I used to suffer quite bad during my teens. Its just so aggressive, every few hours there seems to be new ones appearing. It seems to occur when ever I step down the dose. I think having this bad skin has really added to my depression over the last few weeks, it has been especially difficult considering I have been in the process of starting a new job. To top all of that my UC seems to be worst than ever! I’m worried that when I go back to see the Doctor next week he is going to put me on some equally-annoying medication or maybe another course of Prednisone if I’m lucky.

Does anyone know of some natural alternatives that are good for UC, very reluctant to put anymore man-made chemicals into my body.

I have been on prednisone since I was two years old (I am now sixteen) because I have Autoimmune Hepatitis IIa. I would like to point out that there is still a life worth living being on prednisone, maybe I say this because I do not know life without it, but at least we're alive! Last year I had a flare up of the AIH and had to 6x my dose of prednisone. It sent me into a spiraling depression of constant sleep, crying, hopelessness etc....but I made it through. Just PLEASE keep hope that things would get better, because I know what it's like being on the dreaded drug better than most.

May 25th, 2009
11:20 A.M.

Started Singulair 5/14/09. Within last week or so started having extreme pain in shoulders, hands (especially thumbs), wrists and hips. Put ti down to arthritis. Pain has been getting worse every day. Thought it was a food allergy so stopped eating fruit and have cut out all sugar. Yesterday realized that pain has increased so it wasn't the food. It suddenly dawned on me that it could be the Singulair. Stopped taking it last night and am already much better. Still some pain but not so excruciating.

About a month before my Dr. gave me Advair. After a few days on it, I went to bed and thought I was having a heart attack. Pain across my back and down my arms, up my neck and across my chest. This happened 2 nights in a row and decided to stop taking it. Called my MD and he said to stop it immediately. However, he thought it really might be my heart so I had an echo cardiogram and stress test. They said my heart was perfect. After 2 days off the med had no more trouble..

My take is that these "air" drugs are not for me. My MD is on vacation and won't be back until Wed. I will speak with him then. Hopefully by then all paij will be gone. Will post again to report results of stopping Singulair. Reading all these posts also made me realize my depression, irritability and crying has probably been a result of this drug.

By: Fed Up

I was diagnosed with Rheumatoid arthritis at the end of 2007 and have been on prednisone since then. I started on about 105mg a week and am currently trying to reduce it but it is really hard as the moment the dosage goes down I lose all mobility and cannot even get out of bed. I am only 23 years old and really feeling the disease to the extent that I cannot even cope with my life. The prednisone has really taken its toll on me and the side effects are crazy! I just want to go back to my old self as I am finding it sooo hard to get through a single day. My side effects include:

Insomnia, tooth sensitivity, depression, anxiety, mood swings, moon face (my face is so swollen that I cant stand looking in the mirror anymore, dizziness, temper, feelings of uselessness, nightmares, night sweats, water retention, and to top it all off the arthritis is getting worse and I am in constant pain. Is there anything anyone can suggest then please help me!

I have taken this medication for years (in long stretches). I was not aware of some of the serious side effects not just with this drug but with corticosteroids in general. There is a group of side effects that can cause mental and cognitive issues. I experienced fatigue, confusion, confusion, inability to focus, and serious memory issues. It was bad enough I would completely forget what I was doing or be unable to understand anything if there were other noises. After doing some research I found that these inhaled steroids can have just as many and as severe side effects as oral steroids. I dosed down off of Flovent over a months time and gradually all of the horrible cognitive issues went away. This may not be a very common side effect but they have to tell people it can happen. How many other people have gone years living in a fog not knowing it was a simple asthma inhaler causing their problems.

my boyfriend has been on prednisone for 4 years and he is terribly snappy and aggravated all the time and short tempered and does not think that he is... i love him so i deal with it but its getting harder because he dosnt feel this is correct every time i ask him something he bites my head off and almost everything i do irritates him gets on his nerves the mood swings are out of this world sometimes and he totally thinks im being a lala in his words...will someone respond to this so i can show him and he will know im not just saying these things
all this

I have been on Prednisone for 3 months for PMR (polymyalgia rheumatica)and so far the pros have far outweighed the cons. PMR is an extremely painful condition that affects the shoulders and hips especially at night and early morning, I spent all of December and January sitting upright in a chair trying to sleep, untill I was diagnosed and prescribed Prednisone and oxycodone. I started at 25 mg and I'm now down to 15mg. The side effects that I do have are weight gain (about 10 pounds), mild mood swings and insomnia.I am an avid bicycle rider (25-35 training miles per day on week days a lot more over the weekend),I am 60 years old and now back on the bike. The strange thing is after about one month back in training I am much stronger this year than last even with the added weight. Last year, a solo, 30 mile hard ride I would average about 17 mph this week I went out on my same training ride at 19.4 mph, over 2 mph faster. Everything I read about Prednisone says that it wastes muscles,but I have become stronger. Is it possible that it's the Prednisone?

I am a physician. Kenalog is one of several injectable steroids that can cause subcutaneous atrophy or lipoatrophy as a side effect. For those who have this reaction, they will notice a dent or divot. This is not dangerous problem and most of the time the dent or divot will fill back in with time. How much time? The range is 3 to 24 months without treatment. However, for many patients this healing process can be speeded up with weekly saline injections that can be safely performed by almost any Doctor and need not be expensive.

The technique was well described in the Journal of Dermatological Surgery in 2006. If you do a google search for the name of the article as listed below you can find the Abstract and take a copy to your Doctor.

Best to all,

T.

Treatment of Local, Persistent Cutaneous Atrophy Following Corticosteroid Injection with Normal Saline Infiltration

Shumaker Peter R., MD*, Rao Jaggi, MD † , Goldman Mitchel P., MD †

Published in Dermatological Surgery, 21 Mar 2006

ABSTRACT
Background. Injections of corticosteroids are commonly used for a variety a dermatologic conditions but may cause local, persistent cutaneous atrophy, with few therapeutic options.

Objective. To determine the effectiveness of bacteriostatic normal saline infiltration on the improvement of corticosteroid-induced cutaneous atrophy.

Materials and Methods. Four patients with corticosteroid-induced atrophy of the skin, two caused by acneiform cysts and one from intramuscular steroid injection, were treated with weekly injections of normal saline directly into the atrophic site. The patients were seen on weekly follow-up visits, and improvement was documented.

Results. All four patients demonstrated complete resolution of skin atrophy and restoration of surface contour within 4 to 8 weeks of initial presentation. Injected volumes of normal saline ranged from 5 to 20 cm3 per treatment session and three to six weekly treatments. The patients were completely satisfied with these results.

Conclusion. Normal saline infiltration offers a safe, tolerable, relatively rapid, and effective treatment for local, persistent corticosteroid-induced atrophy.

Dermatologic Surgery, Volume 31 Issue 10, Pages 1340 - 1343,

I was diagnosed with asthma as a child. In late teens it seemed to not be problem, however after 50, I started developing symptoms of asthma again as evidenced from COPD tests. I am currently using Advair 250/50 since 55 yo.

One symptom, that I have not seen addressed here is that of "slow healing" after injuries. I injured my back awhile ago, and it seemed like 2 years before most of my symptoms were gone. To this day I still feel lingering effects. Then I scraped my shinbone. It seemed like it took forever to heal, and now there is an ugly red/purple scar where the minor scrape was.

I had never taken so long to heal before, and read that this was a problem with taking Advair. I never figured my asthma was that serious in the first place, so I simply cut back on the Advair to once/day or less as it seems still to keep my breathing OK. Sometimes, after a few days of not taking Advair, I feel some minor difficulty with breathing.

Now that I am 63, and so concerned about "slow healing", which I attribute to Advair, I have asked my Dr. to perhaps take me off Advair and simply take Albuterol when needed. Then I read that Asthma patients should only use Albuterol if that is sufficient to control symptoms and to advance to Advair to control more severe symptoms. Another article says that Albuterol does not heal Asthma, only assists with sudden onset of breathing difficulties and that I may still damage my lungs if I do not take Advair.

I remain at a loss as to what is best: Taking Albuterol when needed (perhaps a few to several times/week) or as I was doing before, contrary to recommended dosage, of 1-2 times/day. Fortunately my Dr. goes along with my changes, but tells me if symptoms get worse, she will put me on Advair 2X's/Day (which I probably will ignore dosage because of healing side effects, and use once/day or less).

I will report back later after trying Albuterol for time without the use of Advair at all.

I have been weaning off Prednisone for sometime, from 50mg down to 5mg in two week steps, 5mg at a time. I've had quite a few of the physical side effects of Prednisone, though none so severe that I would have considered not taking the drug, as it is helping the neuropathy that it was described for. When I hit the 5mg dose, I really seemed to be having trouble with my mental state. I seemed to switch back and forth from knowing what was going on to wondering if I was starting to go insane or losing touch with reality. Hard one to explain. It seems to occur later in the day when I am fairly tired. Back on 10 mg for the last three days and seem to be tired but not so mentally confused. Don't know if this is all from the Prednisone, though. Has anyone out there had any seemingly similar mental things happen on this drug. Thanks in advance for answering if you have had these experiences, they are scary and am hoping that it is the drug and not something else.

I am a 33 yr old male with Cystic Fibrosis. I started prednisone in 2006 and as of 2009 i have never been off of it.This drug has destroyed my body. I was under weight when i started, at 130 lbs. I am 5'9'' so i admit that was thin,but know i am at 170 lbs. This has had an effect on my relationship with my girlfriend since i met here when i started taking it. It may actually help me breathe better,but I am not sure. I have decided to stop it myself. I will do so slowly,but i am sick of the way i look and feel. This may sound silly to some but i just hate being in this state. I look like a pregnant woman playing a trumpet. I wonder how long it will take me to look like me again? Good luck to all of you. BK.

I am a pediatrician and my and I take care of my one year granddaughter is with allergic rhinitis and bronchial asthma. In her past history other than her usual problems she developed an episode of ketotic hypoglycemia after a viral syndrome.
I started her in Singular as she was having nocturnal episodes of cough in spite of having Pulmicort twice daily. As soon as she was started in Singulair she developed restless episodes of irritability. She never behaved that way before. She is now sleeping well all night after she had discontinued Singular.

I was on prednisone while getting over pneumonia to help with my breathing. I was only on it for 7 days and the doctor didn't have me go off of it gradually. I missed the last dose on the 7th day and by bedtime, my muscles were sore enough it almost hurt to lay down. I took the last pill that night before I went to bed and had no muscle soreness in the morning. After that, the muscle soreness came back, along with dizziness. My pulse was also higher than normal. Two days later at night, I was still having muscle soreness and dizziness, although not nearly as but, but I was having a lot of trouble breathing and my pulse would refuse to go below 100 no matter what I did and the problems continued thought the night. The next morning I went to the clinic that prescribed me the predisone because the information they gave me said to see a doctor if these problems persisted. I told them I thought I might be having a predisone withdrawal because my mother, a nurse, said it was the most likely problem from experience. They completely ignored that saying it had been several days since I've stopped the steroid and kept asking me about my asthma (inhalers weren't working and it was definitely not an asthma attack -- I've had plenty of those, to all different degrees) and ended up giving me medicine for anxiety, which helped the closing of my throat, but none of my other symptoms. Three days later, my resting pulse is down to 80, but my breathing is so much worse than it would be with just my normal asthma and taking my inhalers as much as is allowed. I had no noticeable symptoms when I was on the prednisone except being less able to sleep. If it keeps up, I intend to go to a different doctor to see what is really happening, but I don't think it's 'normal' to have the withdrawal symptoms for this long after only having it for 7 days. I know I took it when I was younger (I'm 22), but I don't remember ever having issues going off of it before.

Hi everyone well yesterday i started to to take Prednisone 2 hour later my heart is racing along with high blood pressure , so ill try to calm my self down blood pressure kind off got back to normal but heart still beating rapid, today i woke up my blood pressure was fine but my heart still pounding do ya know how long it t takes for my heart to go back to normal , and im sorry to hear about everybodys different reactions to this stupid pill hope everybody gets better.

eat avocados to help with cramps. No one tells u that prednisone depletes potassium. Better avocados than banana because prednisone also raises your blood sugar.

for the people that have taken their children off singulair...
what are you using for a preventative med?
my daughter has really bad asthma and I don't know of any alternatives

My 12 year old son has been on 60 mg of Prednisone for two weeks now. His side effects have not been bad at all up to this point. He's gained about 6 pounds. His brain is unusually active right after taking the drug, and this effects lasts a few hours. He's always been a wildly creative kid but prednisone seems to intensify is creativity and the productivity of his brain. He has Tourette Syndrome and his tics waned overnight after beginning the meds so that is a big bonus if prednisone is responsible for that. He has always been an insomniac since he was a baby but prednisone makes him sleepy, so sleepy he takes naps during the day and goes to bed early, sleeping soundly all night, so soundly he had an accident and wet his bed last night. His head sweats when he sleeps. He has infrequent periods of mild irritability. His appetite has increased but not unnaturally so. Seems like he finally has a sustained healthy appetite. He goes to 45 mg for two weeks tomorrow so I'm interested to see what new side effects this brings on. No stomach problems despite taking this along with very high doses of antibiotic. Maybe the prevacid he takes with Lactobacillus is helping with that and the fact that he takes his meds with small meals or lots of fluid.

I have Crohns and had a flare up so I'm back on 40mg of Prednisone. I've been on 40mg now for 3 weeks and I start to tapper off in another 3 weeks. Well every time I start the prednisone again I get new side effects. This time, my gum are bleeding all the time and the pain in my knees are horrible! I still get the regular side effects, ie: Mood swings, joint pain, sleeplessness, sweating, swelling of my legs and hands, wanting to eat everything under the sun, moon face and my hair falls out! I wish the drug manufactures could develop a drug that would not be so hard on our bodies. I have to struggle with the pros and cons with every flare up. Do I want the weight gain, mood swings and hair loss or do I want to look good and be very sick! I'm 37 and was 16 when I found out I had Crohns.

Hi I am a 44 year old asthma patient. I have had asthma since the age 2 and have been on & off prednisone since that time. As a child until age 20 I was on predinsone daily. My question is has anyone experienced nerve problems due to long time use? I do have muscle weakness and spasms, but I am interested in if anyone has had nerve problems. Please email me at ****** and refer to prednisone.

My daughter had been on singulair from the time she was 8 yrs old until she was 14. This will sound as if I am a horrible mother but I just thought that she was a raging bitch. Without my knowledge, she stopped taking her Singulair for a few months and she became a different person. She was so sweet and loving. One night she came in my room having an asthma attack and I asked her if she was taking her meds, she admitted that she had stopped taking her singulair and I got on to her and immediately got her prescription refilled. Within a few days of taking the singulair she turned into a raging, screaming emotional wreck, a TOTALLY different person. I feel so bad that for 6 years of her life I put her on medicine that caused her to have screaming, uncontrollable tantrums, and severe mood swings that caused her to be miserable. It does seem to be the only thing that effectively controls her asthma symptoms but the emotional havoc that is causes her and the people around her is not worth the benefits. We have an appt. with her doctor to see what other options we have.

I found this article on treating the dimpling/cutaneous atrophy effects of Kenalog with saline injections. Very good cosmetic effect.

1: Dermatol Surg. 2005 Oct;31(10):1340-3.
Treatment of local, persistent cutaneous atrophy following corticosteroid injection with normal saline infiltration.
Shumaker PR, Rao J, Goldman MP.

Dermatology Department, Naval Medical Center, San Diego, CA, USA.

BACKGROUND: Injections of corticosteroids are commonly used for a variety a dermatologic conditions but may cause local, persistent cutaneous atrophy, with few therapeutic options. OBJECTIVE: To determine the effectiveness of bacteriostatic normal saline infiltration on the improvement of corticosteroid-induced cutaneous atrophy. MATERIALS AND METHODS: Four patients with corticosteroid-induced atrophy of the skin, two caused by acneiform cysts and one from intramuscular steroid injection, were treated with weekly injections of normal saline directly into the atrophic site. The patients were seen on weekly follow-up visits, and improvement was documented. RESULTS: All four patients demonstrated complete resolution of skin atrophy and restoration of surface contour within 4 to 8 weeks of initial presentation. Injected volumes of normal saline ranged from 5 to 20 cm(3) per treatment session and three to six weekly treatments. The patients were completely satisfied with these results. CONCLUSION: Normal saline infiltration offers a safe, tolerable, relatively rapid, and effective treatment for local, persistent corticosteroid-induced atrophy.

Like so many of you, I Googled "tissue atrophy" and have had the very same experience that you have had with Kenalog. I received a shot in late February of 08, shortly after I noticed severe bruising, which eventually turned into the atrophy I now have. I have taken pictures of it for the past several months...and now, 6 months later it is much worse...deeper and darker in color. Is anyone else having discoloration? Mine is a dark purple-red.
I AM PURSUING a lawsuit against the nurse that injected me because I was absolutely not warned of the side-effects...and now have had to suffer with this hole in my side.

It bothers me...and no one would understand unless this had happened to them I suppose. In addition, I received a second opinion and was told the atrophy was permanent...can anyone else confirm this?

I've also noticed other severe menstrual and emotional side-effects...this stuff can stay in your system for a long time.