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Cumulative effect symptoms and conditions

Here are side effects posted by other members, that mention cumulative effect.
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50 Side Effects posted for cumulative effect

May 2th
2009
12:00 AM

I have a history of sinus infections. After two rounds of Augmentin did not clear up my latest one, my doctor finally gave me the steroid pack and Avelox. He had tried to avoid the steroids. I have had them so many times. I finished my steroids 5 days ago and my Avelox yesterday. I read the side effects and did as it suggested. Since it mentions low potassium would not be good I ate a banana every day and had some orange juice to keep my potassium levels up. The drug warms against taking any pain killers such as Aleve, Advil, etc. One earlier reviewer admitted taking Aleve and had a bad reaction... well.... bad move.... I have had no real side effects that I can say for sure are Avelox related. I did feel a little less focused at times, but was not obviously groggy or woosey. I did have a little abdominal discomfort that I usually do not have with drugs, but it was short-lived and only occurred 3 of the 10 days. Many people have bad effects because they do not follow the warnings against anti-acids, pain killers, low potassium, etc. Some people are more likely to react to any medicine, while others like me rarely have a side effect. My tendons did not hurt... nothing.... People who are out of shape, have a poor physical life style, etc. sometimes help contribute to the drugs reactions by being in basically poor physical health to begin with. America is one of the fattest, out of shape nations out there due to our abundance of everything. The majority of persons can take Avelox with no real issues. I will take it again. I truly feel concern for those who had problems, but sometimes we are partly guilty by how we don't take care of ourselves when we are well...... As with any drug, some persons will react no matter what... It's often just a matter of inherited genetics...... Be safe everyone, and take time to evaluate how you take care of your body and really decide to do better. For the record I am almost 58, 5-9 158 pounds and work out semi-regularly.... Take care of that temple God gave you. Its the only one we get on this Earth,,,,,,

-- By mrsinustis | Reply | (4) replies | Private Message me

February 3th
2009
1:52 AM

I've been taking lamictal for btwn 2 and 3 years now, for depression and as a mood stabilizer. I was on wellbutrin 300 mg, and then I had an episode of severe depression (crying all the time) while on the wellbutrin. So my doctor added lamictal, gradually going up to 200 mg.

It works, and I haven't had a really severe depressive episode since (except for circumstantial reasons), although I'm generally mildly depressed.

Side effects: My fingernails have weakened, and some have ridges down the middle that are so weak they become cracks even if there is only 1 mm of white nail growth. I thought it might be a nutritional deficiency, but I eat healthily, and I finally decided to look into the side effects of my meds. Others on this site are talking about hair loss -- I'm quite sure the nail problem is from the lamictal, as hair and nails are produced in similar ways.

I yawn every few minutes, whether or not I'm tired, which at least one other person on this forum mentioned as well, as a less common side effect. (I'd figured this was due to one of my meds -- now I know which one it is.)
I've also been concerned that I'm klutzier than normal lately. After reading everything on this site, I've just decided to start weaning myself from 200 mg towards a lower dose of 100 mg. I don't think I'll go off of it entirely, b/c it works.
One last thing I have to say is that I really recommend ACUPUNCTURE for any mood disorders. I get it for free at a school in Chicago (it's often a long wait, but free!), and many bigger cities probably have an acupuncture school where it will be cheap, if you're on a budget like I am. Occasionally, insurance covers acupuncture. Anyway, I try to go once a week, and it helps tremendously with my depression, migraines, and general energy level-- it has a very powerful cumulative effect! When I stop going, I notice huge differences emotionally, and I get a lot more migraines. My mom and sister have also had very positive experiences using acupuncture for depression and anxiety.

I actually ask to be treated for my headaches, not specifically depression, but it helps me a lot with both issues. I really can't say enough about how wonderful acupuncture is, and how much it's changed my life. Last time I was medication-free, 5 years ago, I was going to acupuncture every week for many months, and it was enough! Just don't expect it to work overnight -- just be consistent and give it some time. When I first started going every week, I noticed a difference after a month or so, although the treatments generally leave me feeling relaxed and good right afterward as well.

-- By srg | Reply | (2) replies | Private Message me

October 2th
2008
1:17 PM

To the best of my knowledge I never had any of the 'immediate' symptoms.
My problems are probably due to the fact that I was prescribed Cipro 3 possibly 4 times from Aug 06 - Dec 07 and then finished up Dec 07 with a round of Levaquin. My father is over 60 and was recently given Levaquin and had immediate and serious problems. He is seeing a doctor recommended by the CDC today. Yes, he is even working with the CDC on
this one. Due to all he is being told he is convinced that the medication is behind my medical decline as well. Since taking these medications (symptoms started slowly in 07), but after taking the Levaquin at Christmas time I never got up from the couch. My thyroid gland has quit working, my adrenals are shot, I have been diagnosed with fibromyalgia, chronic fatigue, blew out 3 disks in my back, vision is deteriorating rapidly, and really so many things I can't list them all. I had a complete physical
in Oct 05 and was given a perfect bill of health. Through Aug 06 I was riding my bicycle 33 miles per week. I'm still trying to figure out what hit me??
What my father has been told is that in some individuals Levaquin will attack the glands (like the thyroid) and will compromise the immune system. This damage appears to be permanent. All I know is that I went from being extremely healthy to terribly sick. If in a day's time I have enough energy to load and unload the dishwasher it is a banner day. I can
not work and seem to get worse instead of better as each day passes.

My husband also had pneumonia at Christmas and took Levaquin but does not seem to have had an problems. I suspect it was possibly the cumulative effect of having basically 4-5 rounds of the antibiotic in a years time. According to the people at the CDC that have spoken to my father the symptoms that I have can all be traced back to the medication. One never knows what effect a medication will have. Just please be careful when taking this medication, and limit how many times you take it.

-- By cdsgoddess | Reply | (2) replies | Private Message me

June 11th
2008
1:23 PM

I had my left lung fill with fluid and collapse after radiation treatment for Breast Cancer. The lung was drained with Thorocentesis and I was hospitalized for a week and put on prednisone - 40 mg reduced to zero in 1 week. I experienced symptoms of heart attack as reaction to reduction from prednisone. When it was determined by enzyme testing in hospital that heart not damaged I was sent home with prescription of prednisone starting at 60 -10 days, to 40- 5 days, to 30 - 10 days, to 20-10 days. The cumulative effect of these doses was all the side effects mentioned by others, loss of emotional and physical balance, stability, swelling, moon face, insomnia, depression, crying, stomach pain, constipation, etc. I dropped myself to 20mg for 9 days but on the 8th day had recurrence of lung pain and feared possible fluid build up through tissues damage/leak caused by radiation - they are calling it pleurisy or pleural effusion. (It was also determined that I must be on constant oxygen and sleep on oxygen as my breathing capacity is below 88 off of oxygen.) Dr. found not enough fluid to drain without risk to damaging my diaphragm so upped the prednisone again to 30 for 14 days. Using pain and shortness of breath as a measure of lung condition I must not dampen pain now but suffer it to monitor my lung so as to avoid trips for constant X-rays. I continue to suffer from prednisone and it has disabled me so that my normal life cannot be resumed in any way. I want to get off of it, but after reading these reports, I am very worried - supposedly the steroid is allowing my radiated lung to heal, but if that is not happening I think the steroids are possibly more life threatening than the lung - in any case, what life? What other choices do I have to survive the damage done to me by radiation?

-- By catherineh | Reply | (2) replies | Private Message me

May 18th
2008
10:18 PM

I had the Mirena inserted a little over a year ago. Over the last year, I've grown increasingly not myself...wanted to crawl into bed and do nothing. My relationships with everyone changed-husband, parents, children, neighbors, work. I became a hermit. My skin looked unhealthy, it actually hurt to the touch, my body ached like an 80 year old woman. I felt hot all the time. I felt 4 months pregnant. Could hardly climb the stairs often. I weigh currently 155 and am 5'6". At my 6 week checkup postpartum, I had lost all but 8 lbs of baby weight. Couple of months later, had mirena inserted, and voila gained 15 lbs over the next couple of months. It was a cumulative effect...over the next several months, my face was swollen, my hair, skin, chest was extremely gross oily. I couldn't think straight, my and get through the day. I couldn't remember simple things. What got me out of bed was knowing that my children had gone outside and I didn't want them to run into the street. I knew something wasn't right, but it didn't occur to me that it would be the mirena. I went to my general doctor complaining of EXTREME fatigue. I thought maybe it was my thyroid. The doctor ran 3 blood tests...TSH, mono, blood count. All came back normal. Doctor wanted to put me on anti-depressants and recommended therapy. Not that I'm opposed to the recommendation, but it just didn't sound like the solution. I went to another doctor for a second opinion. Also wanted to put me on antidepressants. I didn't want to mask whatever was going on. I wanted to get to the bottom of this. There was a reason for my feeling this way. I just was not myself but truly didn't think antidepressants were the answer. Meanwhile, I scheduled my annual gyn appointment. The IUD hurt at times, I was constantly aware of it anyhow with sharp jabbing pains, and my husband could feel it during intercourse. So I went in thinking I was pretty sure I'd ask for it to be removed. Still not attributing all these dramatic changes to the mirena. When I saw the dramatic weight gain after the IUD insertion, it sealed the deal in my mind. I wanted it out right then and there. Much to my surprise, joy and relief, I instantly felt better in my abdomen. That night, I put my jeans on and they were actually looser. My body was in constant swelling/PMS mode - due to the artificial progesterone. Within a couple of days I had lost 5 lbs and my jeans continued to get looser. It's been only 6 days now, but each day I feel more and more like myself. My weight is dropping, I have more energy. I want to garden again, a hobby I no longer enjoyed whilst having the IUD, I want to take walks again and exercise, which I had no energy to actually do. It feels better to "be in my skin" - weird to say, I know. Before the IUD was removed, my skin felt uncomfortable. My neighbors noticed the weight loss and the already noticeable change in my complexion. I'm able to engage with my children and meet their needs, whereas before I was barely getting by. It's going to take more time I know, to get rid of this awful acne, remaining weight, greasy skin, etc. but I am 100% certain all these changes to my body and mood were because of Mirena. Today, I have a headache settling in. I think it's because my body has been artificial progesterone heavy, suppressing the estrogen, natural balance. It's got to learn to kick in with my own normal hormone function. I'm expecting some ups and downs, but am thrilled that it's out and I'm on the road to recovery. One thing I question is why doctors so highly recommend the Mirena? I asked for the copper IUD and they steered my toward the Mirena, even when I was nursing. Why don't doctors warn patients of the likelihood of depression and the whole host of other problems that I had and so many other women report? I'm very glad I didn't start taking antidepressants because they come with their own side effects, and I would have had a harder time getting to the root of the problem. Only when I had the IUD removed did I google mirena side effects and realize that thousands upon thousands of women have been through the same thing.

-- By kinderkat | Reply | (2) replies | Private Message me

March 30th
2008
10:17 AM

As a pediatrician I write for singulair every day.
The medication is for allergies.
Allergies cause adenoidal swelling, which cause sleep disturbances which makes the child tired the next day with makes him over weight, less attentive, hyper and eventually act out.
This in turn makes the child experience parental, peers and teachers criticism/ abuse, with leads to the child feel inadequate, embarrassed, frustrated and eventually depressed and suicidal.

Yes, singulair does cause behavioral change but they appear within the first couple of peels, the rest is due to allergies, lack of medical care, i.e. sleep, singulair, and zyrtec deficiency.
Allergy shots cause 4 times the incidence of suicidally than singulair, and Ritalin 10 times more.
They say in hebrew "once a stone is thrown into a well, thousands of smart people won't find it".
Check it, it's true.

-- By doctothemax | Reply | (11) replies | Private Message me

March 15th
2008
6:10 PM

There is an important point that everyone here is missing. I had been on Toprol XL for years, brand name. Recently, a generic version by Sandoz has been issued. It is the GENERIC metoprolol that is causing the side effects, the racing heart, etc. If you can get the doctor to write "no substitutions" on the prescription, and get the original Toprol, you will notice the difference. the problem is, health insurance wants to push the generic, so you will pay more. but it's worth it to feel better!

-- By teresazu | Reply | (3) replies | Private Message me


 

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