Daily dose symptoms and conditions

Joint pain in fingers, joint pain in knuckles, wrist weakness after a week on 10 mg daily dose of Zetia. Amazing reduction in bad cholesterol and triglycerides when used with daily maximum 80 mg dose. Zetia was discontinued because of these painful side effects. 68 year old male.

I first started Lisinopril hctz about 3 years ago. Within the first day I had hives, a rash, itchy skin and RED RED face. Dr says it will go away. So I keep taking it. Fast forward a month and I start coughing, coughing at night so bad my husband can't sleep. It's so bad I feel like I'm choking and cough so much I am almost throwing up from the dryness and my throat being so constricted. During that time, I also start having some big whopping sinus pain and pressure. Felt like there was a tennis ball in my sinuses. Big time pain, headache. Dr says nothing wrong, just some allergies. I start taking Benadryl at night to sleep, to help with the itching, wheezing, coughing. It seems to help a bit. So I deal with all this. ALong with the coughing at times I am having trouble getting in air. Almost like I have to force it in. Not sure if it's my throat, sinuses or my chest. Next comes, some bass drum booming of my heart. I think it's so loud in my chest and my ears that others can hear it. This still happens on occasion. At times my legs feel like tree trunks or cement and I just don't have the energy to do anything. My hair started falling out in GOBS. I go to derm doctor, they say it's stress. It'll go away. Next I have kidney pain.... this goes on for a few months... come to find out I have a stone. But I never had any kidney problems before. Doctor's say it could be from the hctz and my kidneys having to work harder, but they were speculating. GP says keep taking Lisinopril hctz the benefits outweigh the side effects. I asked him if he has ever had a kidney stone he says no. I keep taking it. Leg cramps come next, bad cramps. I go to dr and he says it's my potassium, the hctz has depleted the potassium in my body and need to start on some big styrofoam potassium pills. All this goes on for almost two years. Fast forward to now. I'm still beat red in the face (and cannot handle the sun), coughing, sinuses full, itchy and bass drum beating (on occasion), heart flutters (on occasion).... four days ago I almost fainted because I was so dizzy within two hours of taking my pills in the morning. I am by no means able to sit on my butt and do nothing because of all these side effects. I have a farm to run, horses to feed and ride, hay to bale and put up, and I'm ready to get my body safe enough to start trying to get pregnant. I start doing research and find Lisinopril to be UNSAFE for a fetus. I start to think, well if it is unsafe for a fetus why is it safe for me? So then I googled side effects of Lisinopril and it brought me here. Thank God, I have a GP appointment tomorrow. I'm taking control back of my own body. I've had enough....

I took 4 of the 10, 500 mg daily dose of Levaquin that was prescribed to me. My heart rate was so fast that I thought I was going to have a heart attack! And now I have this awful rash all over my body. It's been 4 days since I 've had the last dose and it's not getting better. Does anyone have any idea when this itchy rash will go away?

Male 58 years old.

In September 2000 I had a heart attack and consequently underwent an angioplasty/stent procedure. Since then I have been taking 10mg of simvastatin daily.

During the last 12 months I noticed the following symptoms developing...Occasional dizziness... pain in thumb joints to the extent that I had trouble using cutlery...some pain in my right elbow joint...dry skin on my legs...tingling in fingertips and toes...headaches...tiredness...occasional general muscle fatigue for no apparent reason.

I am generally speaking quite active and have kept my weight to a reasonable level. I put some of these symptoms down to my age...... but then read peoples posts on this site.

Approx 2 months ago I stopped taking the statin tablets, ZOCOR, and have only been taking .75mg of dispersive aspirin daily along with a 1000mg vitamin C tablet dispersed in water.

Since doing this I have noticed that ALL symptoms have been gradually fading...I still have some slight discomfort in my thumb joints but hasten to add that its nothing compared to what it was only two months ago.

Have read elsewhere that a daily dose of vitamin C can help keep cholesterol levels down so am going to stick to this regime and have a blood test in about six months time to see how things are going.

I went to my primary doctor last Wednesday. He gave me samples for a 5 day regime of Avelox to treat a head/chest cold. Well, the cold does seem a little better, but, I would have never traded that to the side effects I am experiencing now! I took my first daily dose of Avelox last Wednesday. On Friday I thought I had dry skin. By Sunday I was itching so bad that it was almost unbearable. My eyelids are itching, burning and swollen, my forehead looks sunburned from the itching and scratching, my chest, stomach, back and thighs feel tingly and are itching NONSTOP. I am taking an antihistamine, but it doesn't seem to be helping much. I hope this goes away. I cannot imagine what this drug does to people that have allergies and sensitivities to medications. I have never experienced an adverse reaction to medications before this. I would never recommend this drug to anyone.

I had a hip replacement in June, then contracted a staph infection after that (non-MRSA, thank goodness!), for which I have been on a 12 week antibiotic protocol, in addition to having the hip opened again for cleaning and replacement. For the first 6 weeks, I had a PICC line in my arm, which was infusing Oxacillin every four hours 24/7, as well as two oral doses per day of Rifampin. After the removal of the PICC line, I was put on a daily dose of 750 mg of Levaquin (I was also on Levaquin in the hospital, and couldn't sleep for weeks after coming home from the hospital). I have now been on Levaquin for 4 weeks and have incredible pain. The first symptom and most annoying was insomnia, as well as EXTREME rotator ruff pain, stiff fingers, tendor pain in my left elbow, and right knee. I can't walk well, the bottoms of my feet hurt (what's up with that?), and I can't even put on my bra by myself, my shoulders hurt so much. I thought I could take the pain because I just DO NOT want to have the staph infection come back and have another hip replacement, but I think I will actually have to go off of it. It's just too much pain. And I'm worried about long term damage.

I'm 58 years old and I've been on 10 mg Simvastatin for 14 months since I was diagnosed with Diabetes 2. Also Metformin and Glipiside as my bs got up to 499 at diagnosis with high cholesterol.

I had NO IDEA that my suffering the past year could possibly be tied to one of the drugs I've been prescribed. In the first three months after diagnosis, my Diabetes was controlled and I've even backed off some of the meds. My cholesterol also came down beautifully. However, the debilitating weakness and muscle aches (which has increased over the 14 mos.) has become so bad (especially this last week) that I came to the Internet looking for possible reasons for 'body ache'.

And get this: I take a packet of vitamins every day which includes a daily dose of Q10... BUT I haven't been able to take them for about a week and this last week I felt like I was ready for a wheel chair~!!! Worse than it's ever been, knees and feet in horrible condition, hands and wrists unable to open a water bottle. Total body aches so severe it made me want to research something, anything to see what might be the problem.... before seeing the doctor about it!

My shock at seeing my medication here listed with the horrible side effects I'm experiencing has been a revelation~!! I am going to stop the Simvastatinn and see what happens. BTW, I've been an active person all my life, was a 2nd Degree Black Belt and taught Tang Soo Do and know what muscle aches and pains are, know my body (at least I did) and pretty much thought my active life was over.....

Not now~!!! I'm FURIOUS!!

I was on Cipro (daily dose 1500mg) for over a beginning June 08. I'm petite 5'2" about 98lbs.

My feet started to ache. My knee's ache so much it hurt when walking down the stairs. I lost my appetite and couldn't eat. I would wake up constantly at night. I would sleep for hours on hours but would still feel fatigue when I woke up. I would have vivid nightmares which also disturbed my sleep. I would have trouble remembering things also.

After stopping the med's sometime in July. Most of these symptoms went away. I still have problems remembering things.

Now a new symptom has occurred. My hair is falling out rapidly. Every time I run my hands through my hair around 15-20 strands come out. When I shower my hair clogs the drains. A bunch comes out when I brush it.

I'm scared and wondering if anybody else has had these issues. My doctor is referring me to a dermatologist but the next appt isn't until Sept.

I was prescribed Avelox for an infected insect bite. I took my first daily dose Saturday evening. I woke up Tuesday morning with large painful welts covering my neck. They were very itchy and hurt very badly. Today is Wednesday and they are continuing to get worse and spread. I just made the connection today that this rash is likely due to Avelox. Im a healthy 27 year old and Ive never had any allergic reactions to medicine before. The infection in my arm went away quickly, but the rash on my neck is terrible.

Effexor XR has been a life-saver for me! I have been taking 150mg per day for about 8 yrs. Recently, 75mg was added to my daily dose because of a temporary new stress or on my plate - divorce. With the increased dose came constant sweating and unbearable dry mouth. I dropped back to the 150mg dose and the sweating is back to being manageable and the dry mouth is much less. I can't imagine living without Effexor XR - this anti-depressant has literally saved my life -- I know now that life doesn't to be so horrifically painful as was the norm for me prior to taking Effexor XR. I have no other side effects - I have gained some weight but only over the past two years and that possibly can be attributed to my age (50) and the stress of a bad marriage. The half life of Effexor is short and I do sometimes get the electrical shock feeling in my head -- that usually a red flag that I missed a dose. To be on the safe side I keep a dose in my purse as a back-up. All-in-all, it feels great to be 'normal', even if it means using Effexor XR - I hope it never goes off the market. Way-back-when, I initially started out w/ Paxil (helped, but I felt just below the surface of reality and had horrid withdrawals) - then tried Wellbutrin and after a day was so terribly spaced out that I could only minimally function and couldn't even leave the house - got off of that stuff immediately! Effexor just lets me function and feel feelings at a normal volume. Thank you Lord!!

I do think the drug maker should put more emphasize on the side effect! I do believe maybe 98% people who take Lipitor without side effect that is why lots of doctors just ignored this fact. I was on Lipitor for two month with daily dose 10mg. Right after one month, I started neck pain with no reason and lasted a month didn't improve at all. Luckily, I thought about the possible Lipitor side effect so that I stopped to take it. Amazingly, just one day without Lipitor, my neck pain almost went away! I tried on/off Lipitor couple times again, and the results were consistent. But, when I revisited the doctor who prescribed Lipitor for me, he just don't believe this fact! He don't believe I had Lipitor side effect at all and prescribed me some pain killer, and asked to continue on Lipitor!
Thanks to the internet technology! I found this website and knowing so many people do have Lipitor side effect! Because this experience, I realized my mother complained back pain for more than a month with no reason, and she was also on Lipitor. I called her, and just two days after stop taking Lipitor, her back pain gone, she can walk again!
Initially, I angry about the doctor! Why he don't follow drug maker directions about the side effect! Then, I realized that in fact the doctor may never encountered Lipitor side effect either patients don't know it is the side effect or most of patients who don't have the side effect at all! I could argue that a doctor is a high trained professional, who should play cautions! Second thought doctors are human too, once they used to the impression Lipitor has no side effect, they may easily miss the warning sign, even ignored the clear fact like my doctor did!
In my view, both doctors and the drug maker responsible for the people suffering Lipitor side effect, but of cause, the law sue against the drug maker is more effective for lawyers!

I could not find the post from the mom of two who is a pharmacy student to reply to her.

My husband is a pharmacist with over 25 years hospital experience. he never questioned the doctors assumption that it would take 6 weeks to totally be out of his system. all drugs have some residual and cumulative or residual effects. it really isn't magically gone from your system in a set number of hours. especially a daily dose and more so in the elderly, and I have seen this first hand , when they are dehydrated or other wise compromised the drugs can stay in their system for a time and accumulate.

i will update on our son later today, he is doing much better two weeks off

I am starting a new post in the hopes that others will see what I am trying to say about the delayed reaction in those that took Singulair for allergies.

If it is consistent that Singulair does not stop allergy symptoms immediately, then the pathways that eventually stop allergy symptoms involve a change in the mast cell function, development and migration (or some combination).

I asked this question for a reason. Are allergy symptoms stopped immediatedly. My question below:

I have a question that will help me continuing looking for information. I can understand that in the case of asthma that Singulair would provide immediate relief. If it is used for seasonal allergies or other allergies without asthma, does it work right away or does it take a period of days or weeks to be effective? If it takes time, could you tell me how long it took in your situation?

My thinking was going in the right direction if the answer below is consistent of everyone or most.

about 2 hours ago on Apr 11, 2008 by catherineevans, #7045
My granddaughter was put on Singulair for allergy symptoms without asthma. Itching, red eyes, terrible congestion, etc. dark circles under her eyes all the time. When we first put her on this, we didn't see any consistent results for 2-3 weeks, then it seemed to 'kick in.' I don't know if this helps. By the way, she was 9, now she's almost 12 and was immediately taken off when this story came out 2 weeks ago.

Then after seeing one response, I gave my reason for asking.

I asked this question because I have a theory of how montelukast really works for allergies as compared to how it works for asthma.

Asthma is a hyper-sensitive state that gets going because the mast cell has a receptor (the leukotriene receptor that Singulair blocks) that sends a signal along a pathway that causes lung tissue to have that extreme response - the wheezing, the airway constriction.

On the mast cell is another receptor the histamine receptor that causes the secretions that make our noses runs and and stuff up. This is not the same immune response as the asthma response. When I saw a post that somebody's doctor said that Singulair is an anti-histamine, NO it is NOT.

So if Singulair does not block histamine immediately and your child's allergies did not go away immediately, then maybe Singulair is working through some other means such as changing normal mast cell homeostasis.
I know that this seems like "what does this mean?" I am really writing this hoping to God that there are people reading this site that know what I am talking about.

Thank you so much for responding. Your answer actually told me what I wanted to know and confirmed my hypothesis. More answers will help. I hope others respond.

PLEASE respond about the length of time that allergies disappeared if you took Singulair for allergies.

I think all of you folks with side affects are are blaming your ills on Lipitor rather than putting the blame where it belongs: on your own mental health. I am a 65 YO male and I have been on Lipitor for more than six years now. I have no side affects, I work out four days per week with cardio and weights and feel that Lipitor should be added to the public water supply. My total cholesterol has gone from the high two hundreds to under one-forty on a single daily dose of 10mg. All of you hypochondriacs get a grip.

Hello,

about a week ago I admitted myself to ER because of terrible breakout of hives (never had them before) but was covered from head to toe.

Doctor prescribed PREDNISONE 80mg for 4 days, and gave me an IV with the drug a week ago Saturday night (don't know how much was there), 12/29/07, I took my daily dose 80mg Sunday noon. I only slept about an hour or two. By new years eve 12/31, I have started getting cold chills, feeling unbearably cold, then the next day 1/1, I felt like I was 100 years old, all my joints were stiff, I couldn't get up from bed, couldn't sleep much but there is still more.

By Wednesday I have felt even more stiff and hives were not going away, I went to the doctor (my stiffness went away after couple hours in the morning) he prescribed more PREDNISONe for another week, luckily I have stopped taking the medication after 5 days of 80mg, plus whatever they gave in in an IV but I still have what I think are side effects from taking it.

Ankles are still sore, I cannot sleep because an extreme numbness sets in my left hand middle to index finger, it is no numb it hurts like an elephant is sitting on it, that is why I am still up at 4:30 in the morning. When I am up it just tingles. Not sure what to do but can't sleep at all for last 3 days and getting really tired.

If I knew what Prednisone does I would never take any of it, I'd rather deal with hives oh and they still didn't go away, I have had them for about 10 days now, they did stop itching. Honestly I felt very very sick a day after taking it, I didn't associate this with Prednisone, until I found this website. Please if you can stop taking it or see for yourself how much you should take 80mg is definitely too much, for me at least.

Did anyone have to deal with joint stiffness, and numbness how long does it take for it to go away. My wife says to to ER again because I can't sleep I am just very uncomfortable with the numbness and rattle in bed, but guess what they could shoot me up with more Prednisone.

I've been on Prednisone after and allergic reaction to penicillin (Amoxicillin) (bullous pemphigold - large blister on my arms and legs, some on the back and very little on the stomach) I've been on the medication for three days (40mg/day) I cannot standup or move my hands, my entire leg hurts and the foot is swollen (it could be from the penicillin). I'm hoping it will go away after I come off prednisone but has anyone experienced long term pain from this drug?

I'm pretty sure my pain is from the allergic reaction. Has anyone had long term pain from any type of bullous reaction?

I've been taking 1 Berocca per day for approximately 2 months in a row. I just had a thorough health exam and my physician noted that I had elevated liver values as if the liver had to work too hard and that my kidney values were strange, more than bad. The kidney values come from a urin test and one indicator is colour, which of course is different when on Berocca. He can't find any specific explanation for the liver value though (not hepatitis, not alcohol nor pharma related.)

I was on a 225mg daily dose of Effexor for about two weeks before I started to ween myself off because it was doing nothing for my situation, causing ridiculous dehydration, and possibly causing mood swings. I haven't taken any for just over a month and every day I'm still getting the same extreme light-headedness that I got the first time I missed a dose. I have no idea how long this is going to last, and I'm sick of it.

I urge anyone who is researching this medication and considering starting it to reconsider. Tell your doctor you would rather try something different first.

Has anyone noticed facial twitching, particularly of the mouth and lips? It seems to go away when I forget to take my daily dose of Singulair, and only came about after taking the drug regularly for a couple weeks.

Thanks!

I had a stroke 4 yrs. ago and in the tests given it was found that I have Vasculitis. Dr. insists that a low daily dose of 4 mgs. per day will be fine. Have gained 45 lbs. Cheeks are puffy. Itching. Have tried using 2mgs. but sed rate is not good. Have accumulated fluid around the heart. Naturally this causes shortness of breath. Have any of you had similar problems?? Does anyone know an alternative drug??? Would appreaciate hearing from you.

I was prescribed levothyroxine by my nurse practitioner for a "slightly" underactive thyroid. I have experienced at times, headaches (feeling like the top of my head is going to blow off); stomach problems, cramping, loose stools; anxiety, sleeplessness, fatigue and a lowered libido. I am prescribed .50 mcg, but I took that dose for 2 months and then lowered my daily dose, myself to .25 mcg. I felt better, but still tired. I didn't tell my NP that I lowered my dose. After a month or so, I upped it again, just because I still felt tired. I have been on the full dose, once again, for a month. I still have some of the previous symptoms, but am due for a blood test this month to see where my levels are at. If they are close to being correct, I am going to ask her to lower my dose or stop it all together and try exercising more. I don't know that this is a horrible drug, but I am sure that it is not something to mess around with, if you don't absolutely need to be taking it.