Discontinuation symptoms and conditions

My daughter is about to turn 5, she was prescribed SMZ-TMP a few days ago in order to prevent another ear infection.
She has been having terrible diarrhea, which is obviously normal, but along with that she started vomiting, she is now vomiting every time after taking the medication. She has a loss of appetite and has barely ate anything in the past 3 days! The poor thing has been battling diarrhea while throwing up at the same time along with terrible stomach pain/cramps. I am calling the doctor first thing tomorrow morning to discuss discontinuation of medication etc.

Damn reading up on all these side effects shared here is really scaring.
Well I must admit that I certainly can relate to quite a few of them.
Well I took Yasmin for over a year,and my initial experience (say 6 months) was ok.
During that times my skin became flawless,to clear&radiant the best I'd ever had.
However beyond the 6 months things changed and I developed mad constant thrush
Really it was horrid,was put on fluconazole countless times,and I had never been one prone to thrush.
Furthermore every month during my period I'd get this mad headache coupled with dizziness and serious fatigue.
I was even convinced that I was anemic,because I'd actually go pale!Due to these headaches I decided to stop the Yasmin as I
Felt that really my life was at stake.In fact it was so bad I couldn't complete the that months pack.
Discontinuing Yasmin,opened yet another can of worms,perhaps due to me stopping suddenly.I developed severe acne,I was never one skin issues.
Well perhaps it could be attributed to the abrupt discontinuation of the pill.Sadly even 6 months of being off the pill my skin has not gotten any better.
As a result I have stupidly found myself having no choice but to go back to Yasmin.I have been taking it for just over a week,my skin has improved profoundly but I'm scared.
Moreso after reading everybody else comments,I'm really scared.If I'm to discontinue would yoi advice that I complete the cycle and not not stop suddenly?
Right now I'm ok just have slight nausea and occasional dull aching head.
Please can somebody give me advice.

I believe that my friable cervix is from the hormones so close to my cervix that are constantly being released from my NuvaRing. All tests for STDs and abnormalities came back clear. Other than that, I do not have any noticeable side effects.

I'm a 45 y/o female with PCOS, T2 Diabetes, IR, and a history of infertility. Back before I knew I had PCOS, I was prescribed clomid,and was finally able to get pregnant. Anyway, after my 3 girls were born ( the last 2 were twins), I went on Nuvaring. LOVE It. I have none of the symptoms anyone else here describes. It keeps me regular, and helps me avoid perimenopause hot flashes and sweats. Once I tried experimenting with going off of the nuvaring (so that I could use supplemental progesterone cream), and I gained weight!! Like, 18 POUNDS! My periods stopped and I was a mess. My endo had me go back on the nuvaring, and I resumed normal periods, and life. But now, I am being asked to give it up again, because it was noted during a recent colposcopy (exam with a magnifying scope as part of a follow up to an abnormal pap), that I have vaginal inflammation. I was told to go off the nuvaring. Well, I didn't even know I had vaginal inflammation. Now I'm off the ring, and .... guess what? My weight is going UP again. Has anyone else experienced weight GAIN with DISCONTINUATION of their NuvaRing? It was explained to me that since I have PCOS, the nuvaring might have helped to keep my weight down as it was suppressing my excess testosterone. GADS! What to do?

I was on Diovan HCTZ for a number of years for my high blood pressure. It worked pretty well, keeping my b/p to around 130/80, it had been 158/90. The Diovan, since no generic is available, is expensive but I did have a prescription plan at the time. I recently retired and asked my doctor to switch me over to a generic medication to cut my cost. He put me on lisinopril hctz 20/12.5mg. I took it once a day and had great results with lowering my blood pressure. No side effects until the third month, I then began to notice a great deal of hair loss. Since I am 58, 15 years post menopausal, dye my hair, I thought maybe it was the dye (unusual since I have been using the same product for years). I started washing my hair every other day instead of daily. This did not help, I still had to vacumm my bathroom floor daily. At this point I looked up on the internet and found this site about the connection of lisinopril and hair loss. Being an RN I decided to cut the pills in half for a week and see what happened. Sure enough, my hair loss stopped. I then went to my doctor equipt with this information. I am now on HCTZ 25mg daily and taking my blood pressure 2x/day. My b/p stays around 140/80. I know I have to go back to the doctor next week to discuss what to do next because this is not working. Luckily I HAD very thick hair otherwise I would be bald. Does the hair grow back? Does anyone have any other medication they can suggest that does not have this side effect? Too bad, I was doing so good on the lisinopril with my b/p and it did not make me tired like the diovan did.

I have been weaning off Prednisone for sometime, from 50mg down to 5mg in two week steps, 5mg at a time. I've had quite a few of the physical side effects of Prednisone, though none so severe that I would have considered not taking the drug, as it is helping the neuropathy that it was described for. When I hit the 5mg dose, I really seemed to be having trouble with my mental state. I seemed to switch back and forth from knowing what was going on to wondering if I was starting to go insane or losing touch with reality. Hard one to explain. It seems to occur later in the day when I am fairly tired. Back on 10 mg for the last three days and seem to be tired but not so mentally confused. Don't know if this is all from the Prednisone, though. Has anyone out there had any seemingly similar mental things happen on this drug. Thanks in advance for answering if you have had these experiences, they are scary and am hoping that it is the drug and not something else.

Hello everyone. My name is Michael, and my experiences with Advair were so horrific, I thought I would post here as a both a cautionary to those who would use this product, and to validate those who thought "they were crazy" while using it.

I was diagnosed with "World Trade cough" as a result of my four month exposure from that disaster. It finally culminated in frequent walking pneumonias and a sinus-drip initiated cough, which is really part of a complicated process from GERD, also World Trade related. Finally, the pulmonologist diagnosed the obvious "RADS", Reactive Airway Disease.

I was prescribed Aidvair Diskus inhaler 500/250 twice a day, along with Nasonex and Nexium. The first two months seemed uneventful. As my cough cleared, I saw no reason to take the medication anymore and slowly titrated its discontinuation.

Then everything went awfully wrong and my nightmare started. First, panic and anxiety attacks, which I hadn't suffered since World Trade overtook me at different times of the day. Only the Toprol for my high blood pressure kept me under control and out of the E/R with uncontrollable tachycardia. Next, the Depression which also was overwhelming, and the compounded fears from physical symptoms. Then the "TRUSH" came in my mouth and a concomitant fungal infection in my groin. Swollen glands in my neck. Fever, fatigue, listlessness joined the symptoms.

Though a committed heterosexual, a bachelor party a month ago raised spectre's too awful to contemplate and I insisted on the most ultra-sensitive diagnostic blood tests to rule out dreaded disease ( I did responsibly use a condom ). The 24 hours from yesterday to today were like sitting on death row, awaiting an answer. ALL NEGATIVE, including Diabetes.

Then I saw this site and had to enroll to tell this story. All of it was here from the THRUSH, which scared me the most, to the Depression and anxiety attacks, which made my fears really get out of control. The Advair had nearly destroyed my immune system.

I am taking "CLORIMAZOLE" for the fungus, which is no bargain...liver toxicity and nausea. Still, far preferable to the feared diseases.

I learned that so-called "modern medicine" is little advanced from the witch doctor. If you read the Pharmacology inserts, half the time they don't even know why something works, and they can't isolate the good effect from the bad. Then, they assault your body with another extreme ( anti-fungal ) to combat what they caused from the first medicine.

My new girlfriend is Chinese. Next time I am sick, I am trying alternative medicine. In the meantime, for anyone prescribed or handed a sample by their doctor, AVOID THIS MEDICATION IF YOU CAN!

I have been on Zoloft for about 8 months. I began taking it for anxiety, depression, panic attacks, and eating issues. Since I have been on it, my eating issues have gotten a lot worse. I began binging, something I've never done before. I have racing thoughts and feel like I am just floating through life. My weight has gone from about 120 to 155. I am not happy, and am considering coming off of the medication. Has anyone else noticed they have not been able to control their eating while on Zoloft? However, my anxiety did subside.

I posted the following information belolw under Simvastatin, the generic equivalent of Zocor, which may apply to the brand name as well:

"In follow-up to my posting 3-days ago, regarding an adverse reaction to Simvastatin 80mg, I would encourage patients/consumers to directly send their complaint to the web sites listed at the very bottom, if you are either a U.S. (FDA Form 3500) or Canadian resident. Also, if your physician is unresponsive to your negative experience with generic Simvastatin, inform him/her that you refuse to continue with this drug, and that you have sent an adverse reaction complaint to the FDA/Canadian equivalent. Provide both your doctor and pharmacy with a copy of the FDA Form 3500 if your a U.S. resident, so they know you're serious. Lastly, I'm back to feeling normal, after I "demanded" my physician switch me to generic Pravastatin 40mg (2 tabs a day - 80mg), manufactured by Teva Pharmaceutical - corporate HQ Israel with manufacturing facility in Pennsylvania. By the way, a 90-day supply of this quality controlled drug is available at Walmart Pharmacy for $10. I hope this helps, especially seniors on a fixed income. -

U.S.A.
http://www.fda.gov/opacom/backgrounders/problem.html

CANADA (http://www.hc-sc.gc.ca/dhp-mps/alt_formats/hpfb-dgpsa/pdf/compli-conform/gui-44_consumer_complaint-plainte_consommateur-eng.pdf). Contact Name: Drug Compliance Verification and Investigation Unit Tel: (613) 952-9906 Fax: (613) 954-0941 E-Mail: DCVIU_UVCEM@hc-sc.gc.ca "

In closing, I would encourage discontinuation of your statin, if it's made by a company based in India or China (call your pharmacist, they can tell you the country of origin).

I have been taking Lisinopril 10mg every morning for about 1 1/2 months. I have been developing many different side effects, but primarily they consist of muscle cramps (painful!) in the legs/calves, numbness of feet with pain when walking, severe itching (it feels almost like ants walking all over my body), and horrible belching and flatulence. I did not connect it to the Lisinopril until I had ruled out all the other medications I have been taking and then coming across a web site that outlined the symptoms I have been experiencing. Why the symptoms occurred gradually and not all at the same time is bewildering, but it is definitely an allergic reaction of some type. I have discontinued the medication as of today and will call my Dr. in the morning and discuss (Yeah, like he'll really come to the phone!) The constellation of symptoms only highlights the strong and potentially life-threatening symptoms that could have occurred. A major anaphylactic reaction could have led to difficulty breathing, atrial fibrillation and probably death. The doctors who prescribe medications are not always aware of the potential harm that could result from the side effects of the meds they prescribe. It is vitally important that we report all symptoms to our doctors and/or pharmacists, nurses, etc. This drug may need to be further investigated. (An FDA approved drug which results in severe side effects can be pulled from the market and doctors told not to prescribe it while a further investigation is completed. Reading the previous posts, it is apparent that many individuals are having similar problems.
The itching is the WORST!!
My advice to anyone having even the slightest symptoms or if you are experiencing more severe reactions to report this to anyone who will listen. If your individual MD finds nothing wrong, invite him/her to imagine how devastating the symptoms can be and literally demand discontinuation of the drug and a prescription for a safer, effective drug.
The advertising campaigns for the drug companies constitute a very massive push to prescribe any and/or all of the meds brought to the marketplace with little regard for those of us who are suffering. This must not be allowed to continue. The unfortunate aspect of discontinuing this med is that the high blood pressure I currently have was fairly controlled by the Lisinopril, but the side effects are impossible and either a new med will be prescribed by my doctor (if he won't listen and/or try to understand, it is time to find a more enlightened physician!) Our fates rest on the combined efforts of all of us to bring the dangers of this med to the forefront. Our hypertension may not be controlled for a few days (until a doctor can prescribe a new one), but the alternative of continuing the med and ignoring or making light of the side effects is far worse.!

Here I go again, unable to fathom my son's suicide, I'm wondering about things again. Could it be possible that maybe some of the side effects do NOT go away with the discontinuation of Singulair? Can certain effects stay with you and do permanent damage? That is if you're on it long enough. A.J. was on it and off of it, (on it more than off) for 9 years. I never caught on. Now that it's too late, and I've learned about this stupid drug, I've got to ask every question that comes to mind. I, too, have asthma and I am tempted to go to my own doctor and request to be put on it just to see what happens to me. Right now I take Advair and I see where it causes problems that are equally as bad for some people as Singulair. I'm one of the lucky ones. It does me well. My depression comes from the death of my son.

P03.16
Idiosyncratic Reaction to Mirena IUS A Cause for Early Removal - Case Report
Sivarajan, S; Aung, SN; Haloob, R
Basildon University Hospital, UK
Background: The discontinuation rate for mirena IUS was around 40%. The common
causes for premature removal were excessive bleeding, spotting, infection and pain.
We all are aware of less systemic effects compared to other progestational agents, We
would like to highlight the importance of exaggerated minerolocorticoid activity in the
form of increased fluid retention and electrolyte changes with spontaneous changes in
weight and generalized edema following mirena IUS which result in early removal.
In our two cases, we highlight the exacerbation of well documented side effects of
progesterone which leads to premature removal of MIRENA IUS.
In my first case,Twenty four hours after insertion of mirena IUS she noticed ankle
swelling, 48 hours later swelling involved the whole lower limb and worse over the
following few days.In addition to heavy vaginal bleeding.At the end of the first week,
she put on weight three quarters of a stone (10.5 lb).Mirena was removed at surgery
after 8 days of insertion and she developed continuous diuresis and profuse sweating
within 24hrs of removal her weight went down by 7lbs.
In the second case ,following mirena IUS insertion Three months later her periods
improved a lot , but she suffered considerable weight gain(7lb) and mood swings. So
she decided to have her mirena removed and opted for Novasure ablation.
Conclusion: Although abdominal pain,peripheral oedema,nervousness are well
documented side effects of Mirena,we couldn’t find in literature of fulminant oedema
and water retention after 24 hours of Mirena insertion. This profound acute side effects
might be due to acute idiosyncratic immune reaction of to progesterone

(extracted from:
******
)

Thank you, Mo, for finding this info on the net!

Claudia

Hi all! I have recently started to have a very strange feeling and thought I would post here to see if anyone else can elaborate on it.

I switched from private healthcare to the VA system in March 2008 and the MD at the VA immediately switched me from Toprol XL 100mg per day to Norvasc ( Amlodipine Besylate) 5mg, a generic version and from Zetia 10mg to Zocor. This is mainly due to the fact that the VA does not have the Toprol XL or the Zetia in their pharmacy.

I am a very active person, work out 3 times per week, play tournament level racquetball and generally stay very active. I was feeling fine on this medication for almost 3 years with the only side effect being a little light-headed feeling with hard physical activity. Approximately 2-3 weeks after changing meds I started to get this lumpy feeling in my chest and then it started to progress into an air hunger feeling which felt like my breath was being taken away for a split second. I called the MD at the VA and requested to go back on metoprolol tartrate, which is what the VA has in place of the metoprolol succinate (Toprol XL). The air gasp feeling has only gotten worse and with any excertion I become tired now and start to get the gaspy feeling. Very scary. When it started to get real bad one evening I called 911 and went to the emergency room. Tests came back "ridiculously normal" the ER MD stated. Went back to the VA and the same MD, who doesn't listen, says I am under stress and prescribed me Paxil. I am completely lost as to what to do. I am going in to have another EKG and a holter monitor put on as well as a stress test.

Does anyone have any advice for me? I am desperate to get this resolved as fast as I can. Feel terrible lately and the MD doesn't seem to be listening to me.

Help!

My son is 9 years old and been on Adderall XR for about 3 weeks and says he hears voices and they tell him they are going to hurt someone... He also has become very aggressive with his siblings... Has anyone else ever had this happen.. Please Help

I have read everyone's symptoms that have written their concerns on this website and I want to recommend that you contact the U.S. Food and Drug Administration website at: www.fda.gov and it will give you all the information you need on the side effects of this drug.

Believe me, many of the symptoms you have all described are on their list under the section that I browsed through when I looked up Lisinopril/HCTZ or ZESTORETIC (the generic kind of this drug).

This what I found:

ADVERSE REACTIONS

ZESTORETIC has been evaluated for safety in 930 patients including 100 patients treated for 50 weeks or more.

In clinical trials with ZESTORETIC no adverse experiences peculiar to this combination drug have been observed. Adverse experiences that have occurred have been limited to those that have been previously reported with lisinopril or hydrochlorothiazide.

The most frequent clinical adverse experiences in controlled trials (including open label extensions) with any combination of lisinopril and hydrochlorothiazide were: dizziness (7.5%), headache (5.2%), cough (3.9%), fatigue (3.7%) and orthostatic effects (3.2%) all of which were more common than in placebo-treated patients. Generally, adverse experiences were mild and transient in nature, but see WARNINGS regarding angioedema and excessive hypotension or syncope. Discontinuation of therapy due to adverse effects was required in 4.4% of patients principally because of dizziness, cough, fatigue and muscle cramps.

Adverse experiences occurring in greater than one percent of patients treated with lisinopril plus hydrochlorothiazide in controlled clinical trials are shown below.

Table Percent of Patients in Controlled Studies

(For a more detailed breakdown of this chart, pls. check the fda website)

Incidence (discontinuation)

Dizziness 7.5
Headache 5.2
Cough 3.9
Fatigue 3.7
Orthostatic Effects 3.2
Diarrhea 2.5
Nausea 2.2
Upper Respiratory Infection 2.2
Muscle Cramps 2.0
Asthenia 1.8
Paresthesia 1.5
Hypotension 1.4
Vomiting 1.4
Dyspepsia 1.3
Rash 1.2
Impotence 1.2

Clinical adverse experiences occurring in 0.3% to 1.0% of patients in controlled trials and rarer, serious, possibly drug-related events reported in marketing experience are listed below:

Body as a Whole: Chest pain, abdominal pain, syncope, chest discomfort, fever, trauma, virus infection. Cardiovascular: Palpitation, orthostatic hypotension. Digestive: Gastrointestinal cramps, dry mouth, constipation, heartburn. Musculoskeletal: Back pain, shoulder pain, knee pain, back strain, myalgia, foot pain. Nervous/Psychiatric: Decreased libido, vertigo,
depression, somnolence. Respiratory: Common cold, nasal congestion, influenza, bronchitis, pharyngeal pain, dyspnea, pulmonary congestion, chronic sinusitis, allergic rhinitis, pharyngeal discomfort. Skin: Flushing, pruritus, skin inflammation, diaphoresis, cutaneous pseudolymphoma. Special Senses: Blurred vision, tinnitus, otalgia. Urogenital: Urinary tract infection.

Angioedema: Angioedema of the face, extremities, lips, tongue, glottis and/or larynx has been reported rarely. (See WARNINGS.)
In rare cases, intestinal angioedema has been reported in post marketing experience.

Hypotension: In clinical trials, adverse effects relating to hypotension occurred as follows: hypotension (1.4%), orthostatic hypotension (0.5%), other orthostatic effects (3.2%). In addition syncope occurred in 0.8% of patients. (See WARNINGS.)

Cough: See PRECAUTIONS - Cough.

I found this website to be helpful information in trying to find out more about the side effects I have been experiencing after taking this drug. I also wrote in to the U.S. Food and Drug Adminstration with my concerns to see what we can do to get it off the market or have it improved.

There is alot more information about the drug and its generic brand as well, but I thought this was important to put on this website. Hope this helps!

Martha

I hav ebeen taking Prozac now about a month, and for a few days now, my hands and feet have started to itch like crazy, I don't know for sure yet if it is the meds, but when I take it tomorrow and it makes me itch I am going to stop taking it. It only seems to bother me in the mornings, I know sulfer makes me break out in hives, I'm wondering if this drug has sulfer in it. just my hands and feet itch.