April 10th
2008
10:29 AM
My four year old son was put on Singulair about a month and a half ago for allergies/very light asthma. I was told that it would help him to possibly outgrow those conditions, and that we would re-evaluate in six months. At first I wasn't very consistent with giving it to him, but for the last two weeks or so he has had it every night before bed. For the last week he has not been himself. Whining a lot, upset about very little things, much more aggressive towards his sister, hitting, kicking, throwing fits. Twice this week his day care center staff pulled me aside and said he has been acting horribly. Upset about little things, angry, kicking, not listening, being very defiant...in short not acting like himself. Same as what we are seeing at home. It's like his behavior has regressed back to a two year old or worse.
I made an appointment for him today because of these behavior problems, plus he seems to be suffering a possible ear infection and bronchitis again anyway, which is what we started on the meds for in the first place. A co-worker remembered that we had recently started medication, and inquired about whether or not I thought that could be causing the behavioral issues. I did a search on google and came to this site. Reading these stories is like a light bulb switched on in my head! I feel horrible, why didn't I think to ask about side effects, why didn't I think about the meds being a possible cause of his behavior? No matter what the doctor says today, I am taking him off the Singular immediately. I will be in search of natural remedies to treat his allergies.
-- By adschimek | Reply | (1) replies | Private Message me
April 9th
2008
3:31 PM
I wrote about Singulair and depression at
http://www.huffingtonpost.com/doug-bremner/if-prescription-meds-dont_b_95868.html
Doug Bremner MD
-- By jamesdouglasbremner | Reply | (2) replies | Private Message me
April 8th
2008
9:53 AM
Hi everyone. I have posted about my son's bad experience with Singulair. After reading about Dr. Bremner, on this web site I contacted him about how to report my son's symptoms. This was his reply:
I am interested in acquiring information about side effects of this drug. In addition to reporting to the FDA you can report your details to me and I can write about it in the medical literature since this is something that seems to be new. Others can send their information to me as well--you are welcome to post this message at medications.com or other web sites and give this email address and I can follow up with them.
Doug Bremner MD
His website address is : http://www.beforeyoutakethatpill.com
Sounds like someone is listening.
April 7th
2008
8:44 AM
I read these posts and regarding my being quoted as saying that it is unclear whether there are leukotriene receptors in the brain, that isn't true, there are leukotriene receptors in the brain and the relationship between neural systems involved in inflammation and mood is well established. I don't think the misquote was deliberate, I wasnt that definitive when I commented to the reporter on the 'breaking' story (she called me because I had just blogged about it and I updated the blog after I got off the phone). There are a number of parallels with other drugs used to treat medical conditions that have been associated with psychiatric side effects, you can follow the links from the March 27 post "If they dont kill us they will drive us crazy" at
http://www.beforeyoutakethatpill.com/blog.html
Doug Bremner MD
-- By jamesdouglasbremner | Reply | (2) replies | Private Message me
April 6th
2008
11:17 PM
I just want to tell you another thing.
There are leukotriene receptors in the brain" That is the real quote from Dr. Bremner.
When I read that he said "unclear", I said, what?, are these Chinese researchers that have been saying since 2002 or maybe before just "cuckoo"?
So the media deliberately misquoted.
April 6th
2008
10:23 PM
J. Douglas Bremner, M.D., I hope that you google your name and will give us your opinion. We are going in the right direction. We need expert help.
-- By concernedcitizen | Reply | (2) replies | Private Message me
September 19th
2008
10:50 AM
I just came across an article on the online "Huffington Post" by Dr. Doug Bremner, who researched the connection between accutane and depression, called "If Prescription Meds Don't Kill You They Might Drive You Crazy" He explains the link between Singulair, Leukotrienes in the brain and depression. There are numerous articles by him as well that are definitely worth reading.
Jenna M.
-- By zsmom | Reply | (1) replies | Private Message meParents United for Pharmaceutical Safety and Accountability