Drug interaction symptoms and conditions

I had a injection of Kenalog on11/25/2008 since then I bleed for 19 days straight, I notice a white spot and a small indentation with a red spot at the injection site. My doctor refused to listen to my cry for medical needs and even told me his materials to pre form a procedure was expired. I became upset with this and started investigating my drug interaction to learn I had an allergic reaction. I went to him and demanded a MRI. IT was then I learned I had muscle atrophy from a injection of some nature my doctor would get the results and go over them with me. When i asked and basically told him I figured out what happened he became very angry with and such issue and told me I had a mental issue that was incurable and proceeded to call the law on me. I promise since the I have a very large indentation in my right elbow very little muscle left very sensitive very limited use and suffering from major depression over how horrible it looks. And it now is starting to spread to my lower fore arm as well, what can we do. I filed a complaint through the FDA AGAINST THE DOCTOR... ALSO a lawyer here in thr grand rapids area, and my contact the news station to help find answers to WHY SO MANY ARE BEING PHYSICALLY HARMED BY A DOCTOR WE TRUSTED. AND NO REASONS OR EVEN A I'M SORRY!!!!!!!!!!!!!!!!!!!!!!!!!!!!

I have a history of sinus infections. After two rounds of Augmentin did not clear up my latest one, my doctor finally gave me the steroid pack and Avelox. He had tried to avoid the steroids. I have had them so many times. I finished my steroids 5 days ago and my Avelox yesterday. I read the side effects and did as it suggested. Since it mentions low potassium would not be good I ate a banana every day and had some orange juice to keep my potassium levels up. The drug warms against taking any pain killers such as Aleve, Advil, etc. One earlier reviewer admitted taking Aleve and had a bad reaction... well.... bad move.... I have had no real side effects that I can say for sure are Avelox related. I did feel a little less focused at times, but was not obviously groggy or woosey. I did have a little abdominal discomfort that I usually do not have with drugs, but it was short-lived and only occurred 3 of the 10 days. Many people have bad effects because they do not follow the warnings against anti-acids, pain killers, low potassium, etc. Some people are more likely to react to any medicine, while others like me rarely have a side effect. My tendons did not hurt... nothing.... People who are out of shape, have a poor physical life style, etc. sometimes help contribute to the drugs reactions by being in basically poor physical health to begin with. America is one of the fattest, out of shape nations out there due to our abundance of everything. The majority of persons can take Avelox with no real issues. I will take it again. I truly feel concern for those who had problems, but sometimes we are partly guilty by how we don't take care of ourselves when we are well...... As with any drug, some persons will react no matter what... It's often just a matter of inherited genetics...... Be safe everyone, and take time to evaluate how you take care of your body and really decide to do better. For the record I am almost 58, 5-9 158 pounds and work out semi-regularly.... Take care of that temple God gave you. Its the only one we get on this Earth,,,,,,

I am just in shock. I have been on Avelox for 7 days now, and I can tell you that the side effects are not worth it. I still feel sick and have the bad cough. Now, I also have Thrush. But the weirdest and most upsetting part of this was that I didn't notice any of the other symptoms. So I went all week, talking a mile a minute, sweating, dry mouth, hallucinations, etc. Then on Saturday, a few of my friends staged an intervention. They actually believed that I was taking Crystal Meth - ICE. I was heartbroken, confused, and mad. I knew I had not done any illegal drugs, but several of my friends were convinced.

I went to the doctor today and found out that it was the Avelox. However, I had already taken today's dose. I even told the doctor about the situation with my friends and asked if this drug could be related. He said no, it must be the steroids and sent me on my way. As luck would have it, the pharmacist saw me in the store and approached. I asked him if Avelox could make me feel the way I was feeling. He told me that I should have never been prescribed Avelox and Effexor as they had drug interaction issues. He also told me that my symptoms were disclosed on the pamplet. The problem was that I got the Avelox as samples after the Augmenton didn't work.

So, I came home took the meds for the Thrush and watched tv. I haven't slept since Thursday, nor have I eaten since Saturday. I am hearing and seeing things. Now I am scared to go to sleep because I may not wake up. My heart is beating fast, I can't stop talking, dizzy, blurred vision, disoriented but extremely happy given the circumstances, paranoid, jittery, extremely thirsty even though unable to pee.

This is just horrible. I am not a drug adict and do not do Meth/Ice or any drug like that, but now my best friends are doubting me. They don't understand or believe that an antibiotic could do this and how am I supposed to prove it to them? It looks like, just because I got sick, I may lose some of my closest friends... Remember, most drug adicts and alcoholics DENY it first. Great, huh. Now everyone is going to be watching me to see if I am on drugs. I feel violated because evidently I got all high on this antibiotic, didn't enjoy it, and now am suffering the consequences.

What makes it worse is that people I love now don't trust me, and I didn't even know what was going on

I've been taking Niaspan for about six weeks now; I started out at 500mg for the first three and I'm now on week three of 1000mg. I hadn't had any side effects and I was thrilled because I can't take statins (though I do take Lovaza with success). My doctor mentioned -- but did not stress -- the "take an aspirin ahead of time" or "eat something with it) thing, so I haven't been. Three nights ago I work up from a very weird dream about my house being on fire and couldn't go back to sleep, partly because I felt hot. I got up and looked in the mirror, and as others have described, I was beet red on my neck, chest, and arms, and very itchy and hot. The "rash" was mottled at the edges. It reminded me of sun poisoning. I wasn't sure what to do; it was 5 am and I knew my partner had a bad night with sleeping already, so I didn't want to wake her. I took a Benadryl. I was wide awake, so I got onto the computer to do some stuff (never thinking I should research the damn thing!), but about 20 minutes later, I felt itchy on my stomach. I went into the bathroom and looked again. My stomach and lower back were now getting it! Interesting. I went back to what I was doing, then about 10 minutes later, my stomach was hot, so I looked again. Now my stomach and all of my back were covered, and I noticed that my neck wasn't as red. Hmmmm... 20 minutes later I looked again, and now my neck and chest were pretty clear (but still itchy) and my butt and upper thighs were getting it (stomach and back still had it). I could actually feel it breaking out on my legs! 20 minutes later, my stomach and back were clear, and my legs were covered. about a half hour later, it was completely gone. I wracked by brain trying to figure out if it was something I ate, a new detergent, a drug interaction gone wrong, but I could think of nothing. I never associated it with the "flush" my doctor told me I could get. This was so much more than a flush. The next night I was so tired that I took a half an Ambien and slept through with no problems (and remember, I had no issues before this, at least that I could remember). I thought it was a fluke. I then spoke to my father yesterday about The Rash, and he asked if it could the the Niaspan, as he had taken it before (but the flushing had been too much and he stopped). I did some research and through that I found this page. Bingo! I had already taken the Niaspan, so I couldn't try the aspirin first. Last night, I woke up at 3 feeling hot and looked, and sure enough, it was starting on my face and neck. I took a Benadryl and went back to bed. I finally fell back to sleep. I'm still a little itchy, though nothing unbearable. Tonight I will try the aspirin a half hour before and eating something non-fatty with the Niaspan. I'll give it a week to help, then I'll call my doctor. I hate to give it up if it works because I am just about out of other options to lower my cholesterol.

I was giving prednisone for only 5 days (not sure about dose, but it tapered to one pill on the last day) for a bronchitis induced severe asthma attack. I have only had asthma twice in my 50 years, both times associated with a bad case of bronchitis. The "doc in the box" reduced his original dosage due to the 3 corisone injections I recently had in my spine. After reading these posts I feel grateful I wasn't on a higher, longer term dose. I have some of the same side effects listed here including uncontrollable appetite, fat gain around the middle, water weight gain, constantly having to urinate, superhuman energy, heart palpitations, and approximately two weeks after finishing, I began to get a mustache (hairs that were previously white became brown over a two week period). I have read on the internet and been told by my pharmacist that this is temporary. I have also read and been told that the 2mg estradiol I take every day since my hysterectomy causes the body to retain and not rid itself of the steroids as it normally would (estrogen is actually listed as drug interaction with prednisone). The doctor in the box apparently just ignored this interaction and prescribed it anyway. However the main reason I am posting is a very strange possible side effect that occurred approximately 1 week after my final dose. I was awakened in the middle of the night with SEVERE pain (felt like bone pain, not muscle) in my right knee that lasted until morning. By mid morning it was gone. The next night I had the same experience but in both knees. It lasted about 5 more days, gradually tapering in intensity, and then just went away. I do have severe arthritis in my lumbar and cervical spine, having had surgeries to repair injuries from a snowmobiling accident. I have normal arthritis elsewhere for a 50 year old, but have NEVER had issues with my knees. Has anyone had this strange symptom? None of my doctors (internist, rheumatologist, physiatrist - who gave me the injections and prescribed physical therapy for my spine) had any explanation. The only explanation I have is the prednisone because I had taken the Z-pac (antibiotic) with no side effects several times in the past. Weird!

Incidentally, I am off the prednisone for about 5 weeks, am still hungry all the time, still fat, still bloated. Unfortunately the extra energy is gone. Best of luck to everyone on this strange drug. My heart sincerely goes out to all of you on long term therapy. God bless.

I am 39 years old. I have been taking Lisinopril for nine months now, for my High BP. For the first 7 months I had not really had any annoying side-effects other than a mild dry cough. But for about the last 2 months I am having a really odd sensation in my heart. It seems like a flutter and it goes across my upper chest area and into my throat. At times they are mild and other times, during a lot of moving around, I have more aggressive sensations. One night while in bed. My wife got her stethoscope out, (she has a medical background) and listened to my heart. She told me not to tell her when I get the sensation, but to let her try and determine when I have the feeling. this nailed it as soon as I had one. She said that it seems that my heart if pumping too quickly. Meaning that I may have a Premature Ventricular Contraction. This has really scared me. I am scheduled to see my Doctor tomorrow. In my last visit which was about 3 weeks ago, I had brought this up to him. He didn't really try to hear my heart on his own. He just listened to what me and wife were explaining about the sensation. I had hurt my leg about the same time this started happening, and I was taking large amounts of Ibuprofen. So he partly chalked up to Ibuprofen and maybe a drug interaction and stated that I lay off the Ibu and see if they go away in 2 weeks. And if not, he wants to do a Holter Monitor on me to see what may be happening. Well they haven't stopped! I am thinking maybe I should ask for a different BP med. I still want to do the Holter to make sure, but I think it may be time for a change. I have only heard of this fluttering feeling happening to one other person. Has anyone else out there had this same scary sensation? if so please let me know what you have done or have found out. Thank you!

I have been taking Lotrel 5/10 for a while now. I don't really remember how long because I have symptoms of Alzheimer's. But I also take about 15 others meds. It did lower my blood pressure. A couple of months ago my chest started hurting so bad my wife took me to the emergency room. I spent 3 days in the hospital with numerous tests to find out my heart is fine. I am still exhausted all the time, I have noticed when I stand up for a while my legs and feet turn purple in large spots. If I stand up from being bent over I get dizzy, chest and throat tighten, and I feel like my shoulders and arms get very heavy. I can't really do any activity, even walking out to the mailbox is hard. It finally came to me that it is probably the Lotrel. My wife called my doctor today but he hasn't called back yet. Has anybody quit cold turkey? I don't want any more of this.
Has anybody had these sort of effects and been switched to something with less side effects? Let me know please.

I have been on Levoxyl for about 9 years and have felt awful. I have had weight loss, dry hair, thinning hair,dry skin, muscle aches, migraines and the list goes on. I just got out of the hospital Monday after 4 days of testing of my heart and lungs. I was admitted for racing heart. The doctor's conclusion was anxiety! They said that Levoxyl has nothing to do with my rapid heart rate. The endocrinologist prescribed taking levoxyl .050 on day and .075 the next also a beta blocker, Xanax and Zoloft. I can not take any of these meds b/c they make it almost worse. I KNOW it is not Anxiety and it from the Levoxyl but what do I do?? I am a mess right now can not be in this condition with four young kids and a husband. None of the doctors would say it was the Levoxyl and instead prescribed more and told me to check up with blood work in 6 weeks. I took the .050 yesterday around noon and by 7:30pm my heart rate picked up again and continued until 4:30 this morning. I can not sleep more then 2 hours at a time and wakeup feeling like I am crawling out of my skin. PLEASE let me know of any solutions.

Below is the latest ADR report on Singulair from the United Kingdom. I deleted side effects reports by very small numbers of patients in order to keep the post briefer. This shows the total number of reports since Singulair was approved in the UK.

I don't know the total number of prescriptions for Singulair in the UK. It is considered expensive.

Drug Analysis Print
Drug name: MONTELUKAST
Drug name: MONTELUKAST Report type: Spontaneous
Report run date: 13-May-2008 Report origin: UNITED KINGDOM
Data lock date: 09-May-2008 08:00:02 PM Route of admin: ALL
Period covered: 01-Jul-1963 to 09-May-2008 Reporter type: ALL
Earliest reaction date: 01-Jan-1997 Reaction: ALL

Cardiac disorders-TOTAL 64
Palpitations 29
Myocardial infarction 6
Tachycardia 6
Diarrhoea 84
Dyspepsia 24
Abdominal pain 98
Abdominal pain upper 22
Nausea 84
Vomiting 52
Dry mouth 15
Asthenia 13
Fatigue 45
Malaise 32
Sudden death 1
Pyrexia 10
Chest discomfort 12
Feeling abnormal 16
Influenza like illness 17
Irritability 18
Drug interaction 13
Chest pain 13
Arthralgia 59
Myalgia 38
Muscle spasms 24
Pain in extremity 14
Balance disorder 10
Lethargy 16
Somnolence 23
Psychomotor hyperactivity 25
Headache 221
Dizziness 68
Neuropathy peripheral 7
Convulsion 6
Epilepsy 7
Dysgeusia 7
Hypoaesthesia 6
Tremor 18
Nervous system disorders TOTAL 526
Abnormal behaviour 13
Agitation 12
Anxiety 18
Aggression 30
Depression 23
Insomnia 58
Abnormal dreams 12
Nightmare 49
Hallucination 21
Sleep disorder 15
Psychiatric disorders TOTAL 364
Asthma 36
Allergic granulomatous angiitis 43
Angioedema 12
Swelling face 12
Erythema 13
Pruritus 32
Rash pruritic 17
Rash 55
Urticaria 33

TOTAL NUMBER OF REACTIONS 2841
TOTAL NUMBER OF FATAL ADR REPORTS* 19
TOTAL NUMBER OF ADR REPORTS* 1489

Hello To All,

I too am on this med, I have been on it for 1 year as of July 2008-

35 pounds, brain fog, headaches, eye sight for reading, chest pain and fluttering heart beat. My doctor who is my friend has told me that he will up my dose... "Dear God" any more and I will go nuts. Does anyone know of any study done in a medical journal that theu could forward to me so I can show my doctor.

Please email me at ****** I would be so very thankful.

Thanks to all and be healthy.

My grandfather at 86-years-old was prescribed Avelox for bronchitis. The warning on the medication listed by Bayer, the company that makes the drug, states that extreme caution should be used when administering to the elderly. He was also prescribed prednisone, which is a drug that is listed that should NEVER be mixed with Avelox. My grandfather took his own life on April 22, 2008, with no warning signs. He was fine when my grandmother left to go to the store and when she returned, she found him. No other family should have to go through what ours has been through in the past nine days!!!! Do not take AVELOX!!!! We just want to prevent one family from going through what we have been through by warning people about this horrible drug. Doctors need to pay more attention to warning labels and drug interaction- someone needs to stand-up and take some responsibility for medications that harm rather then help!

I was prescribed Levaquin for a sinus infection. Shortly after taking the drug, I noticed a heavy metallic taste in my mouth. After two doses, I did notice the sinus infection was getting much better and decided I was well enough to go out to dinner with my husband (who prescribed the Levaquin). We arrived at the restaurant and within seconds of being seated at our table, I felt an explosion in my head. The pain, slamming through the whole left side of my head, was beating along with my heart! I have never felt head pain such as this. Thank God my husband is a doctor and I quietly told him there was no way I was going to make it through the dinner because my head was EXPLODING! In a our state of fear and embarrassment, he took me home and put me in a hot shower, gave me Advil, steroids, Ativan and Vicodin. I'd never had that many drugs on board in my life! The pain receded from about a level 9 to a 3 within two hours, then completely disappeared after 5 hours. I woke up fine this morning and my husband and I decided Levaquin probably is not a good drug for me, though it does help many other people.

I was in the hospital for a bowel re-section. On the third day, they switched me to Levaquin because I spiked a fever. I was released four days later (after 2 doses of I.V. Levaquin per day) and sent home with three days worth of pills. Ever since I've taken the Levaquin, I've had horrible shoulder and back pain and feel somewhat neurotic. The doctor said that it's a side effect from Levaquin. I have one day left of the medication and will continue to take it, but I'm curious if anyone else has had mental side effects. All I've read about is the joint and muscle soreness. Please help! It's affecting my sleep and daily routine. I don't recommend this and will not take it in the future (not to mention the cost of the medication!)
thanks

I have Asmatic Bronchitis... nothing helped... Azithromyicin was my 1st. antibiotic....... didn't help... then the doctor put me on a 5 day Levaquin 750 mg no refills.... I took them faithfully along with 6 days od methylprednisolone..... All this started New Years eve... today. 1/14,2007 I am feeling a lot better and taking breathing treatments too..... there is not much medicines I can take so I was glad this one helped

Ehemm, haha. umm I started taking Zoloft exactly a week ago. so 7 days. umm it has been fin so far. I think i have been a little happier. oh I have OCD, Depression, and Anxiety disorders, nervousness etc. I am 16..17 this year in September. everything has been fine but, the first like 4 days when I would lie down I started tripping out..it wasn't bad like or scary!! It was real cool! ahha. everything was like molding and moving into one! ahha. anyway. I was also wondering about what happens if you snort Zoloft. I have a few lines in front of me. although I did see one thing of a guy who I assume, has snorted it because there was a question"what happens if you snort Zoloft"..Answer.. don't do it, no good ..makes you feel crappy, etc"..

I've been on Biaxin for bronchitis for four days now, following a trip to the ER for breathing problems. I thought it was allergies. The first two days weren't too bad except for the extreme thirst and not being able to sleep (and the gas). If I happened to go to sleep I would have weird dreams and wake up again. I don't know if was the Biaxin or the hydrocodone cough syrup. With the third day, I couldn't think straight and I couldn't remember words. Could be lack of sleep, I guess. Conversations were difficult. I felt spacey. At the same time, I felt like I was on fast-forward: hurry up, hurry up, gotta go, gotta go, gotta get it done, faster, faster! This is the fourth day. I'm still on fast-forward and still dizzy and spacey. My blood pressure is up and my heart rate is down. My pulse is 55. It's time for another dose, but I'm not taking it. In fact, I'm going off all my meds except the blood pressure pills in case it's a drug interaction that's not mentioned. I'll call my own doctor in the morning and talk to him. I trust him more than the anonymous ER doc.

In Sept, I was given a script for Vytorin as my triglycerides were high while rest of cholesterol was in the good zone. I have taken Zocor for years with no problems at all. I am also hypertensive and type 2 diabetic. I take a lot of medications. I was told that there might be a possible problem and to stop the medication if it did come about, by my primary care dr. The chief pharmasist also talked to me about drug interaction that could take place due to one of my BP drugs. I had trouble from day 1, starting with severe HA. It got worse as the days went on and by day 5 I was a wreck, pains from top of head to bottom of feet and depression issues as well. I was unable to reach my PCP as he was in the Arctic Circle on training exercise. I stopped the medication and it took about 10 days for me to come back to what for me is normal. I then called in a request to go back to the zocor as it had not bothered me in the past. Happy to say that I have only the old problems that I have been living with for years and doing fairly well. I have since been tested for any possible damage and thank heavens there was nothing new. It will be a long time before I accept a change or addition in my medications. I guess if it sounds too good to be true it must be so.

MY SON WAS ON DOXYCYCLONE FOR ALMOST TWO WEEKS FOR TREATMENT OF LYMES DISEASE WITH NO SIDE EFFECTS AT ALL. THEN WE WENT ON VACATION TO THE BEACH AND EVEN THOUGH HE HAD SUN BLOCK, HE STILL GOT BURNED MOSTLY JUST ON HIS FACE. THE NEXT TWO DAYS HIS FINGERS WERE SLIGHTLY TINGLY AND HIS HANDS FELT LIKE THEY WERE ON FIRE. I ASKED HIM WHAT WAS DIFFERENT AND HE TOLD ME SINCE WE HAD BEEN ON VACATION, HIS ALLERGIES HAD BEEN ACTING UP SO HE HAD BEEN TAKING HIS ALLEGRA. I TOLD HIM TO STOP THE ALLEGRA AND IN 24 HOURS, THE BURNING SENSATION WAS GONE. I HAVE BEEN READING THAT OTHER PEOPLE HAVE HAD THE HEAT AND BURNING SENSATION IN THEIR EXTREMETIES. HAVE ANY OF YOU ALSO BEEN ON ALLEGRA OR OTHER ANTI-HISTAMINES? COULD THIS BE A POSSIBLE DRUG INTERACTION? MY SON IS ALMOST DONE WITH HIS 4 WEEK TREATMENT FOR LYMES DISEASE AND HAS NO OTHER PROBLEMS.

This was the worst experience! I started taking Doxy to rid myself of infection that might be caused due to a vaginal procedure. I started taking the med on Monday afternoon, by Thursday night my legs and arms were on fire it seemed. The tingly feeling you are talking about. I completely lost my appetite. I was tired, weak, lightheaded, nauseated. Here it is five days after I have stopped the med and I still feel the burning, tingly skin. Also, I had muscle pain that caused my skin to be sore to even touch. I cringed at the thought of someone touching me for two days. NEVER AGAIN will I take this. I mean, after all, it's strong enough to be used for ANTHRAX, how strong does that have to be?

Due to renal transplant (Kidney) I have to be real careful of what types of antibiotics I take. I took my prescription to the pharmacy. The pharmacist at Walgreens stated it had a major drug interaction with my anti-rejection medication. After working with the doctor they prescribed Sulfameth. It worked wonders. I did feel some sadness and was alittle irritable but that outwayed taking the chance that the upper respirtory infection damaged my kidneys and increased my creatnine to where I would be back on dialysis. so a little discomfort for me helped maintain my way of life and that is living my life to fullest and not becoming or behaving like a victim.

Dear guest 36868, you have been poisoned by levaquin. Your dr is an idiot. There is a drug interaction listed with this poison. This is last resort medicine and it's being given out like candy and turning this country into a "country of cripples". Please send a medwatch report in by going to www.fda.gov and please go to www.fqresearch.org and find some help there for your pain. I was poisoned by this "medicine" two years ago and I'm still suffering the tendon pain. It's gotten worse

I was prescribed Levaquin,by a dermatologist, 500MG for 10 days for a skin infection. I began to have severe muscle/tendon pain within a few days. I took it for 9 days. I stopped taking it 8 days ago, and still have severe arm pain. I feel like I've been doing more than 100 pull-ups. I find it difficult to carry a bag, as it adds to the pain. I've tried Naproxen, but it doesn't seem to help. The pain is worse earlier in the day. I talked to my primary Dr. 2 days ago. He thinks it is from the leaquin in combination with Crestor", a cholesterol lowing drug I take. I also take Femara and effexor. I'm wondering ifanyone has had drug interaction problems when taking levaquin, or if this pain is just from the one drug.I am also experiencing unusual (for me) fatigue, and wonder if this is related to Levaquin also.

For GUEST 30924. I posted two days ago (Guest 30900),
but after I read your post I wanted to add this information for you.

My mouth, throat, and all the way down had been burning
terrible for sometime before I complained about it to my Dr. and learned that it was the Advair. I also told him, "I've done everything, rinsed my mouth with Peroxide, used Listerine and everything I know (including a vinegar solution) which somebody else suggested." His answer was, ""Never
use Peroxide or Listerine after using the medicine, this could cause a drug interaction." He did NOT say it WOULD, only
that it COULD and I should NOT do that. I thought I would pass this information along in the event others might try the same thing.

I wrote the post below this one. I should also mention that I take 600 mg. of Advil for a herniated disc to relieve inflammation, and have read in the meantime, as did another person who posted here, that the excitability and rapid heartbeat was probably due to a negative drug interaction between the two! My doctor knew I took the Advil, and didn't know that this was an effect.

there is a drug interaction between advil and levaquin. please stop taking both drugs and see your doctor. get on www.fqvictims.org