Duoneb symptoms and conditions

After being treated for COPD, first with prednisone (some years ago) and with Advair subsequently, I have suffered waves of extreme fatigue and panic attacks. I don't know if it was the original prednisone treatment or the use of Advair. The dosage was reduced last year from 500/50 to 250/50, but the waves of attacks continue. I cannot attribute the condition to anything else. I am not on any other medications except Duoneb. I do not have high-blood pressure. I have developed a pad of fat on my abdomen, but am otherwise slender. Considering that I eat very little, I am probably overweight inspite of my weighing only 120 pounds. Has anyone else suffered with my problems following the use of Advair (or prednisone)?.

I have severe persistent asthma which is sometimes induced by allergies. I am on Advair, Singulair, Allegra, Veramyst, Protonix, Prednisone, and Duonebs on a daily basis. I can also add in my MDI or my epipen as needed(I have anaphylaxis also, hence the epipen). I am prescribed to use the Duonebs every 6 hours every day no matter what, and I can increase it to every 4 or every 2 hours as needed. Due to the frequent use of Albuterol my potassium and magnesium levels are very low. The potassium level being low causes me to have extremely painful cramps in my calfs and the small of my back and irritability, and the magnesium level being low can then cause my asthma to be even worse. These are the long-term side effects that I have experienced, the short-term side effects include jitters, dizziness, headache, and elevated heart rate (my heart rate almost never raises, and yet after a Duonebs treatment one time my heart rate would jump from 70 to 130 to 70 all in a 10 second period of time). I do not like using Duonebs, and if I had a choice I would not, but it is the only thing that has given me any relief from my asthma. My MDI (Metered Dose Inhaler) side effects are limited to being jittery, and this has been eliminated by using a spacer chamber which my doctor prescribed and was completely free, I just had to pick it up at the pharmacy. The spacer chamber delivers the medicine more efficiently to your lungs instead of allowing some of it to go down the back of your throat into your stomach.