November 27th
2008
1:15 AM
Man oh man. This is the worst experience of my life to this date. I'm 20 years old. An awesome person in my own opinion, but really just fell off the cliff. I just wrote an entire page of how I have been feeling lately to my mother and father with no intentions of giving it to them. Its basically explaining that if I do not wake up tomorrow that its because of this drug (doxy). It has made me so depressed that I cannot bare it any longer and I refuse to take any more of this. I can handle depression but actually sitting here and physically writing a letter is not something I would every do healthy.
I feel exhausted and I don't want to do anything. my stomach is fine but I have gotten sores on my tongue and a blister. I thought I may had picked up an STD from the only girl I have ever been with for my first time about 2 1/2 months ago but everything came back negative after I had already been taking the drug for 5 days. Now I have no clue whats wrong with me and this drug isn't curing my symptoms, its only adding on and making me feel terrible. I do not fear of doing anything to myself but I cant get over the fact that Im going to spontaneously pass in my sleep or something messed up. In fact writing this entire thing is completely unlike me. Depression is a powerful thing.
I will cause no harm to myself, but I think that anyone less educated about depression would. I really feel like if I didn't know everything was normal I would be ready for something to end my life. So I hope other people who are as severely depressed as I am will read this an know that its not the end and you just have to sort everything out.
-- By decline20 | Reply | (3) replies | Private Message me
October 19th
2008
5:27 AM
I found this site by searching for depression and any of the medications I take: synthroid, metformin, glimepiride (amaryl), and lisinopril-hctz. And here's the culprit - lisinopril! I've been taking it for only a couple of months now but it feels like my world is closing in on my and I'm bouncing off the walls in my mind. I'm considering retiring having hit 62 and I thought it would be a happy time but instead I feel locked in a prison, with walls of debt, depression, loneliness, hopelessness, etc. closing in on me. I'm even very close to losing a boyfriend because I've become so clingy and emotionally needy.
I must say that I did stop taking an anti-depressant around the same time that I started with the lisinopril. However, the anti-depressant (Lexapro) was originally prescribed to combat anger and not depression. So I cannot say for sure that Lisinopril is the culprit here. But having read everyone's stories, it is very clear.
Thank you all for telling your experiences with this drug. God bless you all.
-- By virginiak | Reply | (2) replies | Private Message me
September 1th
2008
1:27 PM
I just read the new article about Cody Miller and Dr. Douglas Briggs, who was taking Neurontin. That further confirms the work that I was doing to collect research regarding problems with GABA and suicide. How these drugs affect the brain chemicals is very complicated. I believe that the pharmaceutical companies do know that it is possible for a series of things to go wrong and create terrible adverse side effects in some people - not all.
I will be extremely disappointed if the FDA allows these companies to sweep this under the rug.
Suicide risks studied in drugs for physical ills
By RICARDO ALONSO-ZALDIVAR – 1 day ago
WASHINGTON (AP) — Cody Miller was a high school football player who was allergic to ragweed. Douglas Briggs was a doctor coping with pain from an old back injury.
Both are now dead, hanging victims driven to suicide, their families believe, when drugs prescribed to relieve physical symptoms upset their mental and emotional balance.
*******
This testimony should help strengthen our case for warnings for Singulair.
Neurologist Sought Warning for Pfizer Drug
By JEREMY SINGER-VINE
June 20, 2008; Page B10
A British neurologist who analyzed effects of the drug Neurontin told a court hearing Thursday that he advised its maker -- now a unit of Pfizer Inc. -- to include a warning on the drug's label for potential side effects of depression and aggression, but his advice wasn't followed.
The University of London neurologist, Michael R. Trimble, was testifying at a hearing to decide whether civil cases brought against Pfizer alleging suicides linked to Neurontin can proceed. The hearing was jointly held by judges for U.S. District Court in Boston and a New York state court who are hearing similar cases. In various lawsuits consolidated in the federal court, plaintiffs allege more than 100 suicides were connected to Neurontin usage.
Dr. Trimble described what he said was a "plausible biological pathway" that could lead from the compound gabapentin -- the chemical name for Neurontin -- to suicidal behavior, hostility, and aggression. Dr. Trimble said that in 1995 and 1996, he was hired to write two confidential reports for Parke-Davis -- now a unit of Pfizer -- because the company "was concerned about psychosis in relation to their drug." Dr. Trimble said he was unable to find a link to psychosis, but noted effects of depression and aggression.
Lawyers for Pfizer argued at the hearing that the evidence linking the drug to suicidal side effects wasn't scientifically sound. Under cross-examination, they challenged his description of a pathway as a patchwork of studies that didn't prove a biological connection. Neurontin and generic forms of gabapentin are approved for treating epileptic convulsions, but have also been prescribed widely "off label" for other conditions.
In five of nine patient cases he analyzed in 1996, Dr. Trimble said he saw depression and aggression in patients who had no previous symptoms of the side effects, so he said he recommended to the company that the drug "should carry some kind of warning" for susceptible patients.
Thursday's proceedings were the initial phase of a hearing requested by Pfizer to challenge the opinions of the plaintiffs' experts. Under cross-examination and a subsequent examination by the plaintiffs' attorney, Dr. Trimble said the biological pathway between Pfizer's Neurontin and suicidal events were plausible and supported by a series of peer-reviewed neurology research.
June 20th
2008
10:51 AM
This testimony should help strengthen our case for warnings for Singulair.
Neurologist Sought Warning for Pfizer Drug
By JEREMY SINGER-VINE
June 20, 2008; Page B10
A British neurologist who analyzed effects of the drug Neurontin told a court hearing Thursday that he advised its maker -- now a unit of Pfizer Inc. -- to include a warning on the drug's label for potential side effects of depression and aggression, but his advice wasn't followed.
The University of London neurologist, Michael R. Trimble, was testifying at a hearing to decide whether civil cases brought against Pfizer alleging suicides linked to Neurontin can proceed. The hearing was jointly held by judges for U.S. District Court in Boston and a New York state court who are hearing similar cases. In various lawsuits consolidated in the federal court, plaintiffs allege more than 100 suicides were connected to Neurontin usage.
Dr. Trimble described what he said was a "plausible biological pathway" that could lead from the compound gabapentin -- the chemical name for Neurontin -- to suicidal behavior, hostility, and aggression. Dr. Trimble said that in 1995 and 1996, he was hired to write two confidential reports for Parke-Davis -- now a unit of Pfizer -- because the company "was concerned about psychosis in relation to their drug." Dr. Trimble said he was unable to find a link to psychosis, but noted effects of depression and aggression.
Lawyers for Pfizer argued at the hearing that the evidence linking the drug to suicidal side effects wasn't scientifically sound. Under cross-examination, they challenged his description of a pathway as a patchwork of studies that didn't prove a biological connection. Neurontin and generic forms of gabapentin are approved for treating epileptic convulsions, but have also been prescribed widely "off label" for other conditions.
In five of nine patient cases he analyzed in 1996, Dr. Trimble said he saw depression and aggression in patients who had no previous symptoms of the side effects, so he said he recommended to the company that the drug "should carry some kind of warning" for susceptible patients.
Thursday's proceedings were the initial phase of a hearing requested by Pfizer to challenge the opinions of the plaintiffs' experts. Under cross-examination and a subsequent examination by the plaintiffs' attorney, Dr. Trimble said the biological pathway between Pfizer's Neurontin and suicidal events were plausible and supported by a series of peer-reviewed neurology research.
-- By concernedcitizen | Reply | (3) replies | Private Message me
June 13th
2008
6:19 PM
I am in the family with the 86 year old man that committed suicide because of this drug. He was my father and I will never be able to see him again. This drug caused such severe side effects for him that he did not know what he was doing and killed himself leaving his wife of 59 years, 7 children and a host of grandchildren and great-grandchildren. He had everything to live for and had no effects of depression or other problems until he started taking the medicine. The drug made him sicker instead of better. My family has asked that we received a drug screening from the Medical Examiner to determine the combination of drugs that were in my dad's system at his death. He was also prescribed prednisone, which we have since found out should that the drugs should not have been given together. I would like to take this doctor to task for his incompetence in prescribing an elderly man medication that could cause this result. I am very angry at the physician and will pursue legal actions when we receive the Medical Examiners information. No family should have to suffer the loss that we have had and no experience the void that we have in our lives. My father was a healthy, 86 year old man with a family history of living past the age of 100. We figured he had another 20 years to go. I know that my taking legal action will not bring back my father but I would like to somehow make this drug side effects public knowledge so this DOES NOT happen to another family. This weekend is Father's Day and my only way to talk to my father is standing my his graveside. I should not be doing that. I should be celebrating another Father's Day with him at his home. This drug and his doctor caused his death. DO NOT TAKE THIS DRUG....consult your doctor if he even mentions it in a course of treatment. I would like to be able to present evidence to the Food and Drug Administration of the terrible effects of this drug and the combination of drugs that are given with it. My daughter even said she would like to be the one presenting our family story to Congress during hearing concerning removing this drug from the market. That is my goal....this drug should be removed. I have contacted the Food and Drug Administration and suggest that everyone else do the same. If they get enough complaints, they will have to open a dialog on the drug and some of the families will have the opportunity to speak about the effects of the drug on their lives. I will always miss my father and love him dearly. I know that he was not in his right state of mind when he committed suicide and that the drug caused his actions. My mother found him that day in April when she came home from the store. She will never be the same nor will our family. Again, DO NOT TAKE THIS DRUG!!!!!
-- By ocrsquad | Reply | (2) replies | Private Message me
April 14th
2008
1:29 PM
Predisone is the only other alternative for antibiotic therapy. Predisone has been known for years to have a lot of side effects. Always keep in mind you must be weined from the medicine never stop without consulting your doctor and if your doctor gives you a dose that does not require weining please also consult your pharmacist and the pharmacist really knows the drug compared to your doctor. Doctor's typically only know what the medication reps tell them whereas the pharmacist has extensive medication knowledge and will also know your current medication conflicts. Be sure that your doctor is aware of all medications including all herbal supplements and other the counter medications. With predisone you really have to out weigh the symptoms verses the side effects then determine are they really worth going through to eleviate your symptons. Keep in mind Predisone is a steroid a very potent anti-flammitory and reduces the inflammation so the infection can heal.
-- By mesmerizing_k | Reply | (4) replies | Private Message me
January 31th
2008
11:54 PM
Recently i got switched from Apri (generic for Yasmin) to Balziva. My new gyno said it would be more effective with the other medications (Lamictal and Zoloft) and would help with pms symptoms. For the past few months that I've been on Balziva I've been very depressed and moody. I have two periods a month, which are very painful, breast pains, headaches, nausea, insomnia and frequent break outs, i thought all of which were normal with the switch. Then i started researching Balziva and other closely related pills and all the results found to be very similar.. all with side effects of depression. If you have depression or any similar disorder, reconsider when taking this medication, I am thinking of switching myself, it's nice to get this information from other women in the same situation.. because I sure didn't get it from my doctor. Of course I can't pin point this straight to this exact drug, but it all started once i got on Balziva, and after reading so many other womens comments it makes a lot more sense, mostly with why I have been so down. I hope this helps anyone else looking for answers
-- By sandy1678 | Reply | (3) replies | Private Message me
January 15th
2008
6:28 PM
I'm a 25 year old female. On my second packet of Yasmin. My doctor put me on it for my skin and after having 2 years of just been natural I have noticed the side effects of depression, emotional out breaks, anxiety, excessive worry, nervous, spotting blood, heavy periods, paranoid, excess gas & gastro & headaches. Excessive eating then days of not feeling hungry at all. Which is not me at all. My great relationship with my boyfriend is suffering massively. I don't feel like my happy social self at all. This has happened over a holiday period when I was quite relaxed and had no real worries in my life. I have had depression and anxiety in my history and do battle with the odd bad day from time to time but this pill has made my anxiety become serve to the point of uncontrollable crying and extreme worry over anything I could find to worry about. Just before my period while on the inactive pills I experience extreme gastro. Headaches that don't seem to let up as well. Spend my hole holiday looking for Panadol. I realize this is a fairly new age pill and that it promises hardly any weight again, good skin and so on but I highly don't think its worth it. How much has it been trailed and tested? I rather have bad skin & even carry a few kilo's taking a pill that women have been taking since the 50's- or just be natural.
-- By jemmalovesjoeystill | Reply | (1) replies | Private Message me
Singulair (2) PredniSONE (1) Yaz (1) Avelox (1) Yasmin (1) Balziva (1) Lisinopril (1) Doxycycline Hyclate (1)
January 27th
2009
11:35 PM
I am a sophomore college student who just withdrew from college because of the side effects of depression and anxiety. Yaz is a horrible medication to be on and I would not recommend it to anyone. I am still experiencing the side effects and it is the worst feeling in the world. I used to be a strong, independent person who knew what I wanted out of life and loved it. After taking yaz for about 8 months I feel like I am going crazy, I am so confused, lonely, and scared to be alone because I don’t know how bad my depression might get. There has not been a night in a long time that I have not cried, sometimes even for no reason. Like I said I have taken a semester off from college in hopes to transfer closer to home because the side effects are that serious. If you're not on yaz don't take it, if you are watch for these symptoms because this is a dangerous product.
-- By lax16cliff | Reply | (2) replies | Private Message me