Entire system symptoms and conditions

I took the drug for 2 days for a sinus infection. Midway thru the first day, I started to feel numbness 2 front teeth, palate, upper lip and nose. Thought it was the sinus. Took one more pill.

The shoulder and elbow pain was exacerbated by the pill as I already have tendinitis.

The sinus infection is gone, at least for now. I hope it doesn't come back to bite me!

I started taking Avelox 9 days ago. I was prescribed 14 days of Avelox after a round of Ceftin failed to clear up a sinus infection.
I am an avid tennis player, playing 3-5 times a week. My first bad experience happened yesterday when I went out to play and as soon as I walked outside I had a head to toe tingling feeling. This felt like I had chills but no goosebumps were showing. Over an hour or so later, the goosebumps showed up. This was in 90 degree heat!! I first thought it was dehydration, which it may have been, since I didn't seem to be able to get enough water/Gatorade no matter how much I would drink. This is even at night when I am not in the heat!!
I didn't take the medicine today. Played again this morning. I had the same tingling feeling head to toe, but no chills this time. To explain the tingling, I told a friend my skin felt like it was creepy crawly! It was a horrible feeling again in extreme heat!
I, also, have a hamstring that feels a lil tinge to it. I never have these problems and I am guessing this is due to the medicine, too.
If I walk outside, my body temperature feels like it shoots up! Even though I do not have a fever.
I went to my doctor's office and he is out of town! I asked to see another Dr. and he was "too busy to see me" since he was trying to get to the hospital! I was told to call my family Dr.which I did, only to be told he was also booked and I couldn't be seen. So, I gave up! And, not taking the medicine anymore!! Never again. This will be on my list of 'Allergic to.'
I usually have no side effects from medicines.

Hi, I have been taking lisinopril 2.5 mg for a little over a year now. I am 20 years old and had high blood pressure for my age so my doctor prescribed me to a low dose (2.5 mg) of lisnopril. I didn't think much of it at first because I figured my doctor had prescribed it and knew what was best for me, so I have been taking it over a year now.
The past couple days, I've started to think more about things and am wondering if the lisinopril has anything to do with it. I have definitely noticed that my hairline is receding faster and my hair, especially in the front of my head, is thinning. I have also gained weight over the past year and cannot seem to get any weight off. I never had these problems of losing hair or gaining weight before I started lisinopril.
My question is could the lisinopril, even with the low dose of 2.5 mg that I'm taking, actually cause these types of things to happen?
If anyone reading this could please reply to me and let me know, I would appreciate it so much because I am really worrying about this. Thanks.

Welcome a board singulairsurvivor. I received back an email from the woman at the lung association,she was of course sorry for our experiancr,and went on to say the scientist that reviewed the data were some of the best,and the association has no ties to any product.then as i am watching the updates on the hurricanes,i am inendated with singulair commercials as once again it is allergy season,so what a windfall for Merck that this article came out this month and not next....Coincidense i think not shame shame shame on you.To all those unsuspecting people about to get their prescription .i am sorry

We have all been saying that our issues regard not being informed about all of the possible side effects. And, we know that Singulair works well for some people. Nobody wants to take a good drug away from those for which it probably performs miracles. People who have toxic side effects have a right to know up front.

My observations about montelukast's chemical structure are either general or not quite 100% correct or could be quite vague - so forgive me. I do not claim to be good at organic chemistry. But from doing a little work, I have come up with some observations.

1. It would seem to me that montelukast might work quite well for people who have developed mold category related asthma. I observed that chloroquinolin, a component of montelukast, is a good fungicide effective against Aspergillus, Alternaria, Cladosporium, Penicillium and Candida. Dust mites can only digest if helped by aspergillus so they go into the mold category. Molds produce millions of spores so anyone who lives in contact with mold would be chronically sick from their presence. Then people get hypersensitized to that.

I am probably wrong but I could imagine that montelukast is: 1) a ligand that binds to an empty cysLT1 receptor for a period of time 2) 7-chloroquinolin-2-yl which either acts intact or breaks down into a quinoline fungicide so that it kills the chronic mold/fungus infection and 3) a sulphur/methyl anti-inflammatory component that tells the t-cells that they are not needed so they will die. Wow, that would be great for mold asthma if it was completely non-toxic. It would be also great under controlled circumstances for many people who are mold-miserable. If I am wrong, I better go out into my garage and start inventing such a drug.

This is my visualization to try to explain the side effects of neurotoxicity. So adverse reactions could be to the quinoline component as an allergic reaction or dose related so that it just built up to a toxic level over time. There are many signs that t-cell populations are significantly reduced by montelukast. The fact that the Italians can do it in the test tube might be that it's a chemical component of montelukast designed to cause the t-cells to die.

Montelukast is a large molecule so Artie says it cannot penetrate the blood brain barrier. That would be an argument if nobody was complaining about neuro-psychiatric side effects. The neuro-psychiatric side effects are identical to quinoline and quinolones. When I read about Lariam, it just sounds like a more extreme version of Singulair side effects. Chloroquinolins were used before they invented Lariam, which is stronger. The malaria Plasmodiums became immune. Hallucinations, anxiety, depression, suicidal thoughts are completely consistent in all of the quinoline/quinolones. If montelukast breaks into sub-molecules then quinolines easily penetrate the blood brain barrier.

I find clinical evidence that montelukast may act as more than more molecule. And, that there is a rational for the existence of the chloroquinolin and evidence that it may be the source of toxicity.

I am glad to risk being called crazy. That is what the internet is for. We can present our ideas and discuss. So, just take this with a grain of salt. If I am close to the truth, this post will find it's proper home.

I don't think I will find much more to research. If you have allergies or asthma, the immune system has become hyper sensitive. But, we cannot allow medications to suppress our immune system in general for the sake of controlling certain symptoms that we are having. Everything in the immune system has a purpose. So good sense would tell us to use as little intervention as possible to keep the entire system running. How to do that is very individual.

If you have a hyper allergic children, read about the immune system first so that you can ask your doctor the questions that you need to ask. Try going to a site that is written for the public.

http://www.howstuffworks.com/immune-system.htm

If your doctor cannot explain how a medication works and only knows that it's FDA approved for asthma or allergies, then on to the next. Any doctor should be able to explain if one part of the immune system is suppressed what happens to the other parts. If you ask the question, what happens to the nasal passages if the receptors are suppressed and the neutrophils don't know that there is an infection? Will my child be more inclined to get sinus and upper respiratory infections? That is just one example.

After I switched to Metoprolol Succinate ER, the generic form of Toprol XL, which I had used for 4 years with no noticeable side effects, I began having the experience of everything moving faster - heart beat, pulse, intestinal peristalsis was highly accelerated. Daily bowel movements increased from one or two normal a day to three or four. After a few weeks this condition was punctuated by brief bouts of diarrhea(not something I am prone to) approximately weekly.

Since nothing else changed in my food, supplement or prescription drug intake, my digestive system has always worked extremely well, without problems; and because I had a colonoscopy showing no abnormalities in recently years and no occult blood in the stool in a recent doctor's visit, I am wondering if the Metoprolol is the cause. My entire system feels like it is on some type of "speed' drug, sort of a mania experience.

Have there been other reports of this with people who switched from Toprol Xl to the generic?

Dec. 26, 2006 - I was prescribed Levaquin for severe sinus infection on Dec. 5. The first night I had severe leg pain. Then I had fatigue and severe arthritis reactions., ie., pains in hands, fingers, arms, feet. I felt like I just let it go too long and some infection was entered into my entire system. The sinus infection was not cleared up so I was prescribed another dose on Dec. 22. I just had to painful days of cooking for the family. I feel like a need to move from the cold weather of WI because I hurt everywhere. I get on the internet (curious as to whether the Levaquin could have this side effect) and find this web site. I'm stopping the drugs immediately.

Lipitor has caused me serious colon problems. I was having severe cramping and bowel movements. The colon contractions were so severe that I would begin vomiting, even though I was not nauseated. After 2 or 3 hours of these bouts, occurring every 1 to 3 days, I would be so weak I would have to go to bed. Then severe weakness overtook my entire system. I have no appetite and have lost 19 pounds since January. Food has no taste and after forcing eating, I don't want anything else to eat after 3 bites. CT scan showed severe edema in the cecum and descending colon plus diffuse inflammation of remainder of the colon. Quit taking Lipitor and cramping subsided almost immediately, but now have almost constant diarrhea. I WILL NEVER TAKE STATINS AGAIN!!!