Genetic testing symptoms and conditions

I posted a story on January 16 about my 16 year old daughter who turned out to have Factor V Leiden. She went on Yaz and nearly died a few weeks later. Factor V Leiden really is very common. Especially if you have Scandinavian blood or red hair. But it affects all races and ethnicities at lower levels. If you want to read more, the New York Times had a good article on February 24, 2008. It was about the decision whether to get a genetic test before going on birth control. B. A.

My daughter was 16 when her GYN started her on Yaz. She was 5 ft 3 and 100 lbs. Non smoker. No risks. She went on the pill because she was having heart palpitations and extreme fatigue that correlated with her menstrual cycle. The idea was to level her hormones and see if that would level off the physical problems. Within 6 weeks she suffered from a pulmonary embolism. Because she was young, everybody though it was just pneumonia or inflammation of the lining of the lungs (pleurisy). Then her leg swelled up and turned blue from a clot (DVT). I found it fascinating that everybody at the first hospital, during the helicopter ride and at the second hospital all had EXACTLY the same reaction . . . They all said, "you just started taking the pill, didn't you? Probably one of the new ones like Yaz." Apparently, these new 'third generation' pills are worse than the old ones when it comes to clots. It turns out that my hubby's history of blood clots should have been a clue that my daughter has a common clotting disorder and YAZ triggered it into action. The clotting disorder affects up to 10% of Swedes and that is where my hubby's family comes from. Up to 5% of all Caucasians in the United States have Factor V Leiden as well. I notified the FDA and highly encourage everybody else to do so as well. The doctor are not required to file a report unless a patient dies. My daughter is doing better now. If any reporters are reading this, please contact me. B. A. ***** If you have ANY family history of problems that might be due to clots, avoid the third generation pills.

Oh My Gosh - as I sit here with abdominal cramps typing my experience - I can see the light at the end of the tunnel. I started taking Lisinopril in late April 2008. On May 2 I had severe abdominal cramps and massive vomiting for 8 hours. Finally got myself to ER after I sent my family on to our vacation (I joined 2 days later). The ER attributed it to food poisoning. Lo and behold, I had another "attack" on May 9th. Back to ER I went (my husband witnessed my attack and insisted I go). They took X-rays and MRI - found intestinal inflammation but didn't know why. My internest send me to gastro dr. Third attack hit on June 5th and gastro doctor sent me to major hospital ER. They, too, did MRI & blood work. Looked at gall bladder, pancreas, stomach, intestines, etc. They found intestinal inflammation. Gastro Dr. took more blood and did more test (CT, MRI, Colonoscopy, Endoscopy). He couldn't find anything so he sent me to rheumatologist. She did add'l blood work and genetic testing. She though I had an auto-immune disorder - like Mediterranean Familial Fever! Please...! But all her tests came back negative. She too had no answers, only treatment for symptoms - Colchicine and Prednisone. Yuk. After having my 8th debilitating attack yesterday (since May), I've had enough. I went to the Web and found this wonderful site - along with some others with helpful info. I don't have confirmation that the lisinopril is causing this - but it sure sounds like it. I am a 49 yr old female and I've had no "life changing" events in my life (except for this nastiness) and have been on no other meds. I find it interesting that out of all the doctors I've seen - and all knew of the lisinopril - that none suspected this as a side effect.

Please let me know if a class-action lawsuit is ever filed against this Pharm Co because I will file a suit to get this dangerous drug off the market. Yasmin/Yaz almost took my life in January 08. My OB/GYN put me on Yaz in Oct 07 for bad periods and cysts on my overies. Within a month my entire personality changed and I started losing my hair. I experienced a complete loss of sex drive, became depressed and was either constanting crying or raging at someone. However, my adult acne did clear up. On 1/27/08 I experienced extreme pain in my calf that moved up to my thigh within 48 hrs. I went to the ER and was told that no only did I a condition called DVT (Deep Vein Thrombisis-blood clot) in my leg but that the clot had broken off and moved into both of my lungs and I had bi-lateral pulmonary embolism. I can't even describe how incredibly painful this was. I was admitted into the hospital for 1 week and was put on powerful blood thinners, which I will be on for about a year. It's now been nearly 6 months since I was diagnosed and the DVT and it is still in my uppper thigh. But am grateful to be alive. If you would like to contact me I would be glad to answer any questions regarding this situation and my email addy is ****** PLEASE DO NOT TAKE YAZ OR YASMIN OR LET ANYONE IN YOUR FAMILY TAKE THIS MED, IT COULD KILL YOU.