Heart valve symptoms and conditions

PLEASE STAY AWAY FROM THIS DRUG! IT"S LETHAL> I was on Advair 500/50 for 2years to control my severe asthma, which it did and for about 6months I felt great, but at what a price?....Chronic Bronchitis, Pneumonia, Teeth Breaking, Bone Density Issues, severe hair loss, most awful leg cramps, dizziness, shortness of breath, night sweats, anxiety and chest pains. I suspected that Advair was too blame, came across this site and it all just clicked!. I immediately quit Advair cold turkey in March this year. In May during my annual physical I had an abnormal EKG and a murmur was noticed (for the 1st time in 20years). My primary care physician of 25years was as baffled as I was,.I had a perfect EKG the year before. She referred me to a cardiologist and he did a battery of tests (EKG, echocardiogram and stress test with contrast).The echocardiogram came back as abnormal with mitral valve regurgitation and tricuspid valve regurgitation. Is it coincidental that some of the side effects triggered by Advair such as Chest Pain, dizziness, heart palpitations is also the common symptoms of heart valve issues? I don't know. I'm not a doctor, but my common sense tells me that this drug is the culprit.
Before taking this drug, I was a very healthy 40 year old. I could run 10miles a day, work 10hours a day and take care of 4year old. 3months ago before quitting Advair, I felt like a 83year old with advance heart failure. I'm finding my way back to almost feeling and looking my old self again minus less hair, broken teeth and a not so perfect ticker, courtesy of GSK and Advair.

I am a 32yo male and a Paramedic and it has been a living hell for the last two years. Here are my side effects and then my story. Anxiety, anxious, Irritable, high heart rate, leg calf pain, horrible sleep, bad nightmares, depression, suicidal thoughts, thoughts of hurting people, hate being around people, fear of heights (I used to rock climb daily), dizzy- if I move my head too fast or spin around with my son, weight gain(could be unrelated) arm cramping, frequent urination, and mood swings from crying to anger in just a few minutes. Not like me at all! First few years looking back, I was just became irritable and short with people. The last year has been horrible depression and anxiety along with the other side effects. I like many of you who have written here have had many of the exact same side effects. I had a stressful job at times and worked 24 hour shifts. I have always loved people, and enjoyed meeting new people. Not any more!! Two years ago my mother who lives 3.5 hours away asked me why I was in such so anxious all the time. She said, you are not the laid back and carefree man I know. I thought it was just due to some stress about being recently married or the job. The changes took time and I did not realize them or see them. Looking back, others knew something had changed.
Knowing about medications for my job and how to research them, I looked into every possible side effect and how Singulair worked before I started taking it. Looked good in 2004 with no major side effects. A little over a year ago my father became sick. He was going to battle cancer, but before he could, he would find out he needed a heart valve replaced. He got the surgery, went into cardiac arrest at home a week later, and was given CPR by my mother. A local police officer shocked him and got the heart out of V-fib. I slept with him in the ICU almost every night. He died a week after that and my wife was 7 months pregnant. Talk about stress. The baby came and I stopped working to raise our new little boy. I became short with my wife and started to pull away from being around people. I started to have bad dreams with twisted and morbid outcomes. I had suicidal thoughts out of nowhere and would wonder, where did that come from. Just as soon as they would come, they would be gone or I would think about something else. I got dizzy all the time and started to get carsick if I wasn't driving. I used to be able to read while riding backwards or sideways in the ambulance without a problem of feeling sick. That was not like me at all. I would snap at anything and became almost OC about everything. Thinking all this time the last year that I was just depressed about loosing my father whom I was very close too. Our little boy ended up having some medical problems and the insurance company would not pay the bills. More stress! My wife an EMT-Intermediate blew out 2 disks in her back on an ambulance run, more stress again. More insurance problems. I became a basket case! More anxiety, more depression, never got a full night sleep, mind racing, calf pain soo bad I would ask my wife to rub them, arm pains and finger joint pains at night. I also had a high heart rate of 100 almost all the time. Heart palpitations and a few times it felt like my heart was empty off all the blood and would beat very hard in the middle of the night lasting only a few seconds to a minute. Weight gain, moody all the time. I thought just due to all the normal stress in life.
Two days ago I went for a hard hike and came back with a pounding headache. Excedrin always does the trick for me. Not this time! I had seen a second of a news where the anchorman was talking about Singulair. Googled "Singulair problem" and found this site. I freaked out!! Almost all of you are talking about all the problems I have had as well!! This medication is making us go completely mad!! Tried to go to bed two nights ago and my mind was just racing. It has been Singulair the whole time. The only medication I take. It has made me nuts. My head was pounding the worst I have ever felt and my heart was coming out of my chest. I was awake since 3:30am and read the story of Cody Miller. This poor boy had no chance with this drug. He brain was not fully developed like an adult at just 15 years old. He wouldn't be able to fight the suicidal thoughts like I can. I have been to a lot of hangings, suicide shootings, and drug overdoses. I have seen plenty of death.
I called his mother a few hours later and explained to her that by them going to the media and getting the story out, prompted me to look into Singulair side effects. And that they just saved my marriage and my life. I explained to her that she did nothing wrong by giving Cody the medication for his allergies. It works great for the asthma and allergy symptoms for me. But, it ruined the last year of my life! I felt like I was going to have a stroke shortly after talking to her. I had my wife check my blood pressure and it was 154/100 (normally 120/82). Got grandpa to watch the boy and went to the ER. After my lab results came back and talking with the doctor, we decided it was a panic attack and who knows what the side effects of coming off this drug will be? I had stopped taking it the night before. Thanks to all of you who posted here and thanks to Kate and David Miller for speaking up. You saved my life. This medication got worse over time for me. It got worse as the stress level went up. I have been off it for two nights and already feel much more calm and was sleeping fine, until the little boy woke up and wanted a hug, or bottle. I hated almost everyone, I was short tempered, anxious, OC, and wanted to hurt people for no reason. I want my life back. I want the old me, the care free happy go lucky guy! I already feel better and will write hear as the days and weeks go by. I will never take Singulair ever again!! Not one stupid pill!! Look to those close to you and see if they notice changes. Even those of you who have been on it for three years like me. The drug company knew what was up the whole time. Bad men and women who want money over telling the truth. Maybe not everyone taking Singulair will ever have the side effects soo many of use have been living with, but to those of you that notice changes! Throw this medication away now and never touch it again. Get your life back!!! Be the old you again. I will go back to Albuterol (the only medication I used to take). Read the stories about the two year olds and the five year olds that cry all the time and are angry all the time. Little kids tell it like it is. It's not until they get to work for large drug companies as adults due they lie about side effects and wait years to publish paperwork saying that post marketing research shows all these negative side effects. They knew all along.

In 2000, I was given a beta blocker for a heart valve problem, and after a few days developed what seemed like Cystitis. The Urethra became extremely sensitive and swollen; I felt like jumping out of my skin; and, within a few days it had turned into a real infection which ultimately migrated to the right kidney causing vomiting and high fever. I was hospitalized. I didn't connect this condition with the Lisinopril, but discontinued the medication because, besides the urinary/kidney infection, I felt very lethargic.
In February 2007, I was prescribed 40 mg of Diocesan for the heart valve problem, and within a few days I began to develop the same symptoms as the 2000 episode, and subsequently developed a kidney infection again. During this very serious infection (high fever, vomiting, couldn't eat for five days), I had discontinued the Diocesan. I lost 17 pounds in two weeks during this event.
Once well, I resumed the Diocesan, and again within a few days the urethra became inflamed and the Cystis began.
This time it occurred to me that the beta blocker and the Diocesan were causing this side effect (the doctors during these episodes were incredulous), but was told that apparently all ".....April" medications would have that effect on me.
Subsequently, I was put on Lisinopril, at a quarter of the usual dose. I've been on it for two weeks and have had no urinary symptoms except for a little throbbing in the right kidney. This worries me. I can only suspect that some by product of these medications is causing an imbalance in the renal and urinary function.

Tetracycline is directly affected to a condition known as Idiopathic Intercranial Hypertension or more commonly known as Pseudotumor Cerebri. It is a very rare neurological condition. It causes Cerebral Spinal Fluid to build up on the brain and therefore causes servere headaches and permanent loss of vision due to pressure built up on the optic nerves. I had taken Tetracycline off and on for many years as a treatment of acne and was always told that the headaches that I had were migraines until I was hosptialized and finally diagnosed correctly by a Neurologist who promptly took me off of the medication. After learning all of this I have done much research and I was already in a high-risk category for this condition and Tetracycline is directly listed on every website as a cause of this condition. I SHOULD HAVE NEVER BEEN PRESCRIBED THIS MEDICATION!!! There are no warnings on the medication to indicate that it causes this condition and my healthcare provider was not aware or she never would have prescribed it to me. Now I live with a VP shunt, blood clots in my brain and constant headaches. What a price to pay to get rid of acne!

My husband is on Paxil cr. Has been for about 8 years. (Was on Paxil and then Paxil cr. He has a plasic heart valve. He had surgery in 1988 first and then in 1996 he had an angorizim (spell?) by it. He has always been hyper and anxious, but this scared him so much. He is on coumadin, metoprolol, digoxin, and colestoral medications. He also started having siezures. He has been on dilantin for about 5 years and still had siezures. The siezures can be from just dizzy, vomiting, to a full grand mal siezure. No one can find out why...Recently he had been put on lamictal, by his nurologist. He has been very anxious, and just angry at the world and depressed. He argues over everything. Could it be that he has been on paxil for a long time and it isn't working anymore or could the lamictal cause this? He deffinelty needs help and I don't know where to turn. He also has had irregular heart beats. went to cardiologists but they say it is electrical, not circulatory and not dangerous. I took him to emergency the other night and they said the same. He is misorable. do you have any advise????