Hefty dose symptoms and conditions

During the three weeks I was using 150 mg. Wellbutrin, ringing in the ears gradually increased, mild headaches on top of my head, occasional light spasms around my mouth, constipation, and bladder problems. My sleep was unaffected, and my depression did not lift. My dose was increased to 300 mg, and by the fourth day, I was having serious facial spasms, intense headaches, louder and constant ringing in the ears, almost 'round-the-clock wakefulness, anxiety, difficulty thinking and completing sentences, pounding heart, amplification of sounds, jitters and quaking. I felt like a car, perpetually idling so roughly that all my parts were about to rattle right off the chassis. On the fifth day I took nothing. I've had some chills, a little nausea, headache, neck-ache (Isn't that weird?!) and some ringing, but at a lower volume that's hardly noticeable. This is the fourth day with no Wellbutrin, and I haven't had facial spasms at all in the past couple of days, have less nausea, and the very funky smell produced in my urine from the second week I was on the meds has calmed down. If I'm still in a depression it's been overshadowed by the most awful side effects I could have imagined. It felt like the spector of death was overtaking my body by day four of that 300 mg. dose. I had been on a hefty dose of Zoloft daily for almost ten years and never experienced anything unpleasant other than weight gain, my reason for trying to switch meds because I couldn't quit putting on weight no matter what. I am going to try SAM-e, and suggest that anyone looking for a natural alternative, with the prospect of few and insignificant side effects, do an online search. Whether I find success with the SAM-e, or if it falls short of what I need, I'll post here to let you know what happens. A month ago I thought the depression was the end of the world; I think the cure was worse than the disease.

I am a 34 y/o male who started taking 10mg/day of lisinopril on May 15th. My blood pressure at the time was 140/118, pretty high I guess! I was feeling it too in the form of headaches. The doc wrote the script for me and I filled it that night. I should also mention that this is not the first time I have taken Lisinopril. I stopped taking it back in March because the script ran out. I don't seem to recall any kind of side-effects the first time, but I could be wrong. Anyway, I also take Levoxyl for my hypothyroidism, and it is a pretty hefty dose, 225mcg a day.

So, for the first week, I was doing pretty good on it. No coughing, or any of the listed side effects listed for the med. Then, about a week into it, I started having numbness in the right three toes on my right foot. When I say numb, I don't mean I could not feel anything, it was like touching your skin with a t-shirt over it. I could feel it, just kind of topically numb. I had a 'patch' of this numb skin right behind those same three toes and several other areas up the front and back of my right calve. I delt with this for a few days, thinking it was my shoes I was wearing at work. They were pretty worn out on the outer edges. I got new shoes on Monday, June 2nd. I wore them to work on the next day. At the end of the day, my calves felt kind of tired. The next day, they felt kind of tired still. I found this sort of weird. From that point on, my high anxiety really kicked in. I don't want to mention the thoughts I am having about what it could be that is causing this. I forgot to mention that I have not been sleeping well lately either since I started taking the Lisinppril again. I guess overall, I feel exhausted and weak. More so in my legs. To add to it, my lower back hurts like mad. I have two herniated discs and mild arthritis in it from damage from years ago. Also, for the past week, a pain has been developing in my left shoulder blade in my back. It is worse in the morning, and had gradually been getting worse for about a week. Today, it was awful.

I have ready a lot of the messages about the side effects different people are having. My question is, has anyone ever been on the lisinopril, gone off of it for whatever reason, having had no bad side effects, then gone back on it only to start having these bad side effects that you did not have before?

I have stopped taking the lisinopril on the 5th and have a doctor's appointment on the 9th to find out what is going on. I don't feel good at all. Can anyone relate?