Homeostasis symptoms and conditions

I know that many here would like the FDA to take a very serious took at the problem. I personally don't see how a review of their data is going to make any difference at all. But, if there are experts who can propose a model of the pathways of cell signalling that include the possibility that these symptoms can occur (and under what circumstance), then maybe the problem will look like something much more than statistics.

This is not my field. But I tried to follow the possible pathways to see if I could identify a possible area of concern. Then I looked for someone who had written in the area and read their abstract. A place to start may be to get an opinion from those who know something about "normal homeostasis of the mast cell." Singular blocks the cysteinyl leukotriene receptor 1 which is a site on the outer membrane of the mast cell (other cells also). The mast cell which is produced in the bone marrow is released in a immature state and matures after it arrives at it's destination. The mast cell does not become active unless it's receptor sites come in contact with the activating agent. So, what happens when a receptor site on the mast cell is suppressed by Singular, a receptor antagonist.

You see, I don't have a clue what the signals are that tell the bone marrow to make mast cells (or what the signals are that tell them where to go after they are made in the bone marrow). Does Singular interfere with something that tells the bone marrow what to do? If Singular does interfere with that process, then what is happening and what period of time does it take to happen? Could we wonder whether Singular is interfering with the NUMBER of mast cells that are produced over time? And, of course, maybe there is some OTHER kind of explanation for why the adverse drug reactions are happening. But, at this level, I got lost and can't go any further.

Maybe this group would be interested in the Singulair problems or could suggest somebody else?

http://www.edata-center.com/journals/2ff21abf44b19838,0a1257122f661a7e,0d8ee7116ef23452.html

I apologize if this lead doesn't produce any results but at least it could be a place to start.

I had a shot of kenalog in my knee for a problem I have when I run long distances. I was told that it would have a 50% chance of helping but it could prevent surgeries. He never mentioned side effects. After the injection- my period came a week late and lasted three days longer than normal. Four days after it ended I got another period. This one was accompanied by severe headaches(I never get headaches) This period lasted another nine days. I went for my follow up and questioned the doctor about it and he said he must have forgotten to mention it but that it can cause some hormone irregularities but that it should go away within a month. I have been so exhuasted and barely able to function. It was five days since my last period and now I got another one today! I am furiouse because I was trying to get pregnant! Now I am freaking out because I am seeing on this sight how long this can really last!

After all of us have had these same problems you think we would be able to sue the company. What can we do becuase I'm on board if you all want to have a class action law suit. How do we start it?