Human beings symptoms and conditions

THIS IS TO MR SINUSITIS AND HIS ARROGANT COMMENT. I am a 22 year old male United States Air Force Reservist who currently has chronic sinusitis and just completed my 7 day trial of AVELOX. I just read everyone comments on the side effects of this horrible pill, and i am thankful i am now going insane lol. I have had the nausea, headaches, very bad body pains, tendon pains and very vertigo feeling ( almost like i am no longer human, too hard to explain.) i am very angered at the person ( mrsinusitis) who had the audacity to call everyone fat and the only reason why we have these side effects is because we are lazy, unhealthy human beings. SORRY GUY... I AM VERY FIT, IN THE MILITARY, EAT VERY VERY HEALTHY AND I HAVE EXPERIENCED THESE HORRIBLE SIDE EFFECTS MYSELF. so please, before you speak, think about what you say. Just because you may not have these side effects, does not mean the thousands of others that are experiencing this are not. THANK YOU. I FEEL ALL OF YOUR GUYS PAIN. AVELOX IS THE WORST MEDICATION IVE EVER TAKEN, other than the peanut butter shot in the butt in bootcamp :)

headache, nausea, body pains, depression, vertigo feeling, cant think clearly, tendon pains, feet feel like they are swollen, back pains, blurred vision.

GOTTA LOVE IT!!!

Hello I'm a 41 year old female, and I took Lipitor 20 mgs for 6 months about two years ago. When I called my doctor's office to complain about side effects they told me it couldn't be the Lipitor because I had been taking it for a month already, and would have had problems before that. I eventually took myself off of the drug 5 months later. Here are some of the side effects I experienced:
Itchy fingertips, increased blood pressure, 30lb weight gain, shaky hand writing, acne, poor driving skills, poor memory, hair loss, "frozen joints", IBS, incontinence, low grade fever, itchy feet, numb toes, numb hands, foggy brain, joint pain, muscle pain, foot pain, plantar pain, dizzy, jaw pain, back and neck pain, week ankles and wrists, nasal allergies, skin rashes, migraines, heartburn, Increase in Astham, heart palpitations, knee pain, difficulty standing up from sitting position, difficulty climbing stairs, water retention alternating in feet, hands, arms and legs, almost constant taste of bile in my mouth.
These are only the ones I can remember. Two years down the road everything but the muscle and joint pain and weakness is gone. even those have improved a lot. I stopped taking the Lipitor and lost all 30lbs I had gained on it, without dieting, in a months time. I still have two toes on each foot that are partially numb. I have trouble climbing stairs, and getting up from a sitting position. I can do both, but I move slowly while doing them. The pain in my muscles and joints drives me crazy, but I'm grateful that the rest of the symptoms have cleared up. My doctor never believed me about my symptoms, and neither does my new doctor really. Went to the emergency room for asthma that was not responding to my inhaler, and they were about to let me go home when I mentioned to the doctor that I had been on Lipitor. Suddenly a huge battery of tests were ordered including a CT scan and a stress test. When I asked the doctor why he said that they just wanted to be sure that it wasn't something other than asthma. Why did they do that after hearing about the Lipitor? Do they know something? Are there doctors who believe that statins are killing and seriously injuring people? I'm so angry. Even as I sit here typing I know when I stand up I will have massive amounts of pain that I will have to "walk off". My quadriceps have not recovered, and remain ridiculously weak.
If I can stop one other person from going through this I will be happy. Thanks everyone for taking the time to list your symptoms. It makes me feel better to know that someone believes me, and knows what I am going through.

Wow - I had a great experience with kenalog in suppressing my allergies. They have been unbearable until getting the shot. I sat down with the doctor who went through the list of pros and cons with the drug. He said, and I agree wholeheartedly (I'm sure we all do) that no is more interested in or more responsible for my health than I am, so he said after going through the risks of meds that I should verify it for myself and if I felt comfortable with the shot he would give it. Can you imagine how much better off the world would be if we all took responsibility for ourselves - actually did our own homework? I've seen doctors before who don't really take the time to discuss side effects so I'm glad he did (but then, how many people ever read the drug information that the pharmacist gives out - can't really blame the doctor for that...). Anyways, given that I had severe symptoms that was affecting sleep and very low risk for osteoporosis I got the shot and man do I feel great!

Well folks, its coming off time and it is no fun. i have only been on l5 mg and under for a short time, but im weaning and have laid aside the entire week for that. im tired, very sleepy, headache and feel as if a spoke or two is missing.lol

I think that I can get my head around certain things and try to explain to you that medications do not work for all people or affect all people the same way. Well, that sounds simple enough to say - DUH. But, it is actually quite complicated chemically. Human beings are not chemically the same because we have variations in our genes. Would you be surprised to learn that about 60% of adverse drug reactions involve certain chemicals (in some cases enzymes) that we already know what these chemicals or enzymes are and what the variants are among populations groups? Some times we can predict who would have an adverse reaction to what medications if we knew what gene subgroup the patient was part of. We could also predict whether the patient would metabolize a drug at the same speed as others or not. Metabolize means utilize the drug and then discard the by-products--mostly the liver is the recycling center of chemical waste. Anything that the liver cannot re-use, the kidneys gets rid of in the urine. Speed of metabolism is a very important thing because people who are slow metabolizers might actually experience over-dose. There are other differences caused by genes that can cause different reactions according to the individual person.

I am interesting in following this site because I am wondering if the concept is flawed meaning that other parts of the body were ignored at the expense of controlling asthma and allergies of the nasal passages and lungs. OR - is there just a problem that relates to genetic differences in something such as enzymes and certain populations groups do just fine on Singulair with no problems and other people have some awful problems?

This isn't my area. But, sadly, if I can spend two weeks looking at this and come up with at least a road map of what I am looking for to answer some important questions then people who do this for Merck already know the answers. Why do I say that? Because, the adverse side effects (major categories) correspond to important areas of leukotriene receptor location and activity. Maybe not necessarily this receptor but part of a chemical process that involves this receptor.

The bottom line is that Singulair is the wrong medication for anyone that has adverse reactions. OR, there is a problem regarding the dosage that involves how fast the patient metabolizes the medication. Considering that there is a link to psychiatric adverse drugs reactions in Singulair and some medications for depression are linked to differences in metabolism due to enzymes, then there could be possibly something important to be learned from Singulair adverse drug reactions.

The biggest problem is that pharmaceutical companies are not properly communicating with the doctors who prescribe their medications. Why not communicate to doctors to look out for side effects and be aware that there are gene variations among people that are directly linked to how the patient might respond to the medication?

What happens if the patient belongs to the gene group that will have problems? If the pharm company does not tell the doctor to be on the alert, then the doctor tells the patient that it is not the drug that is causing the problem. Then the gene groups with the problems, go on the war path.

My opinion:

After many hours of searching scientific databases, I have so far been unable to find any research that has been done on how Singulair (montelukast) affects the brain and brain function. So far, I have also found no funding opportunities for any researchers to study montelukast and the brain. That does not mean that they don't exist, I just haven't located any as of today. I have been to many sites putting montelukast in the search area.

I personally believe that this is a consumer BEWARE situation. I personally would not take this drug after seeing for myself how little we can find out about how it interacts with brain chemicals. The FDA needs to require drug companies to study how medications affect the entire body not just one area. Human beings aren't just a nose and a pair of lungs. And we can't keep going around to different doctors to try to find a fix for a medication that is screwing up other parts of our bodies.

After learning that some researchers in other countries have found leukoteine receptors in the brain of human beings, I find it possible to believe that everyone who takes this medication that suppresses the function of those receptors are in some way being affected by Singulair whether they know it or not. I would want to know that Singulair was studied carefully to show how it affects the brain and what the long term consequences are for those who take it. Until that is done, I believe that consumers should heed the warnings regarding adverse psychiatric drug reactions and consider all of the potential options for safe and effective treatment of their conditions. If Singulair is the best option, then consumers should be told what the risk are and how to handle them.

If any one is following what research is being done, here is the description of the new study in children.

http://clinicaltrials.gov/ct2/show/NCT00540839?intr=%22Montelukast%22&rank=19

Are you aware about short and long term side effects of this Devil's drug??? Of course, everybody reacts differently while take or withdraw. But there are high number of people who react terribly bad!!! Doctors do not want to recognize and discuss this. They just keep silent... Do you know exactly how Prednisone works??? Nobody knows this for sure, even doctors!!! From my personal experience, and despite gradual withdrawal, I developed extremely high blood pressure, weakness, panic attacks, depression! Practically it ruined my normal life! Doctors have no clue how to deal with its devastating side effects. Steroids are not selective. When you take a steroid, the drug infiltrates the nucleus of every single one OF YOUR CELLS AND STARTS MONKEYING AROUND WITH GENES IT FINDS THERE!!! It probably plays with hundreds of genes. And just a small number of these genes control the pain and inflammation associated with inflammatory diseases, so steroids turn many of these genes off which is good thing. However, because steroids are not selective, they also regulate the genes that control kidney, liver, BRAIN, and HEART function - which is not good thing!!! It is likely that steroid treatment plays with other genes, too, including those we do not know about a lot right now...So, Prednisone pervades the entire body, which increases the likelihood of short-term side effects and long-term DAMAGE. My advice is: THINK TWICE BEFORE TAKING PREDNISONE!!!

To the poster above...

Human beings with lack of empathy scare me. What a sad affliction to suffer with. I hope there will be a cure for that one day

Using the Isopropyl alcohol (99%) in a long term for wiping the surface.Is there any chances of side effect to human beings with the inhalation of vapors of IPA.

My brother has been taking Lisinopril for 9 months and since he began taking this drug, he has no quality of life.
His side affects are: Tiredness, tingling in the feet and toes and at times he can't feel the ground under his feet and cannot walk properly on the street, there is dizziness, queasiness, hot flashes an hour after taking the pill, strange sensations in his head, and various other symptoms.
So he cut down the dosage enormously and still the symptoms are there.
This is a deadly drug and shouldn't be given to human beings.

Okay, I have been on Yasmin for about 3-4 months now, and the first month I had almost no side effects, I felt fine. But then by the second month I had waves of awful nausea that still have not gone away so I have decided to switch methods--I'll probably get the shot, depoprovera. However, I fear nausea with this too, since my bidy doesn't seem to like synthetic hormones. The nausea gets worse whenever I got to work because I have to stand at my job. It's a truly miserable feeling. Even after skipping today's, I still feel sick and am having night sweats. I know I am not pregnant because I just had a full period last week. This is just from my experience, but Yasmin is a horrible drug. It will make you feel miserable. It will make you feel dizzy, incredibly nauseated, and weak. I think combination pills are too much hormones to be injected into a person on a daily basis. After all, we're not lab rats! We're human beings. I hate Yasmin and after I find a new method, I will never revert back to it! Ever!

yesterday may 23rd i found myself at the emergency. I could no longer stand the pain and was terrified to see that i had lost 2 inches off my right thigh. I was desperate at this point and broke down in tears yet even at the hospital the staff didn't care...after waiting over four hours and being told it wasn't life treatening i left and returned home in tears. Nobody cares and I am so scared of finding myself in a wheelchair at 49 yrs old. I am already house bound and depression has set in for every doctor i talk to brush it off as if it's nothing. This is my life we are talking about I am a somebody and I do matter, we all do. Someone please help us I beg of you, someone has to still care about human beings instead of money!!!!! God bless you all