Interference symptoms and conditions

Side effects seem to be different with two different brands of Lisinopril.

First maker is International Labs Inc. seems to give me the heavy chest along with more sluggish feeling. Which results in some Ed problems as well. Terrible gas.

Where as I have some Lisinopril from Mylan Pharmaceuticals Inc. which seems to be better.

I was told by someone that the makers may use different fillers to make the pills which I could be reacting too ?

Has anyone else found this to be true, Plus what brands does everyone else get ?

Either way I have been on this Lisinopril for 5 weeks now not liking it much but did get past the terrible couch scratchy throat feel by drinking some milk first to coat my throat, someone told me and it did work.

Waiting to see what troubles show up next with taking this long term. Not sure I can afford the blood work it will require when they soaked me 625 plus 222 dollars for two visits to get this 4 dollar pill.

Maybe they just prescribe this to lower our pressure for when the bills show up for us Unlucky Unemployed people without Health Insurance !!

These posts about contacting a bad viral infection while the immune system is suppressed by Singulair are particularly worrisome. This was from 2007 so it has nothing to do with the FDA investigation. Epstein Barr causes some really bad illnesses including lymphoma.

The scary part is that children are the most susceptible to viruses. They need to develop immunity at a young age that will build up over time to levels that will protect them for the rest of their lives. Why are we giving children a drug that will suppress the leukotrienes? Why do we think that it is okay to take away one of the bodies defense mechanisms? Wouldn't it be logical that a drug that suppresses the immune system is a last resort option not handed out like lollipops?

www.iddb.org/drugs/singulair/ - 243k
.
Anonymous Immune System Dysfunction September 13th, 2007

Do users of Singulair and Advair understand how these products work? In order to understand how they work, you must first know what happens in the body during an allergic attack.

Allergic response is a function of the body's immune system. When an allergen enters the body through the nose or the lungs (e.g., a bit of pollen or cat dander), it is recognized by the body as a foreign substance, and the immune system then produces histamines to fight the intruder. Singulair and Advair work by disabling the body's immune system, so that there is no allergic response.

I too thought these drugs were wonderful. I was on both Singulair and Advair to combat asthma from my new husband's cat. I took high strengths of these drugs for approximately three years.

During the time I was on these drugs, some disease entity, most likely a virus (e.g., Epstein-Barr, Herpes Simplex I, HTLV I). I have been sick with a fever for the last four and a half years. My immune system seems to have been permanently impaired, and every organ in my body is now compromised. I have a fever, night sweats, liver and spleen enlargement, digestive problems, skin infections, hypertension, rapid-onset insulin-dependent diabetes and other endocrino;ogical problems, blood cell abnormalities, and neurological problems (e.g., tremors, myoclonic seizures, muscle cramps and weakness, vertigo, incoordination).

I am about to undergo a spinal tap and other tests, looking for the causative entity. Whatever it is entered my nervous system when I had an epidural anesthetic while on these immune system depressants. I have not been the same since. I have been too sick to work. This has ruined my life.

As we have all learned from recent reports of heart damage from Vioxx, the FDA no longer has the money to fully test new drugs entering the market. The "clinical trials" are a drug's entry into the population. If it kills or sickens too many people, they withdraw it. However, the drug companies define "too many people" as a number that could potentially ruin profits through lawsuits.

MORAL OF THE STORY: Don't rely on the government to protect you. Before putting any drug into your body, do the research into how it works. Read comments from other users. I wish I had done that.

i have a few side effects with januvia i fell stress on my heart high bp high sugar and weekness sleep interference high pulse never had any before and so tired hard to get around doc. dont wont to think its the pill i know it is.mary

Very few side effects. My father was put on 30 mg of Prednisone to control an inflammation that he was having in his body. It seemed to work well. He had also lost considerable weight, had anemia and was admitted to the hospital prior. So I wasn't worried about the common side effect of Prednisone of weight gain, as post-hospital we were glad he was gaining weight. I don't know if it was a side effect, as he only slowly gained a pound or two each week and then eventually plateaued about about his old weight.

We've now started tapering it, at my recommendation, not the doctor's!, and we are not seeing any return of side effects yet. He did have a bit of the puffy face, and is a bit compulsive, but we don't know if that's because of his Alzheimer's or the Prednisone.

I wanted to let some other know, as I've done a lot of reading/research, looking at the prescribing and pharmakinetics of the drug, it seems important that the taper is most critical when you are nearing 5 mg. This is because 5 mg is about the amount that your body naturally makes, so if your adrenal glands have stopped making it, it would take some time for them to 're-awaken'.

Therefore, the typical recommended tapering schedule is something like 10 mg per week, then slowing it down at 10 mg, and then real slow at 5 mg, eventually going to like 1 mg pills, as you try to continue down to no pills.

While I think Prednisone did put an end to a life-threatening inflammation for my father, I like many others would have liked much more upfront info and options from the docs. We are now on a slow 3 month taper schedule, that nobody realized we'd have to do when we started.

BTW, my dad has mild/moderate swelling in his ankles and toes, but nothing in his hands or abdomen. We don't know if it's because of his loss of weight, muscle and weakening of his heart, and/or some interference with his adrenal-regulation from an ACE inhibitor, Lisinopril, that he is on for his hypertension, or the Prednisone.

Any advice on the swollen ankles would be appreciated.

Cognitive confusion; if I had thought something and it was wrong, I would keep remembering the wrong thing instead of the right one...like I would come up with a plan with a friend, we would decide on something else, then I would do the original plan, forget that we had changed it. Could be called "proactive interference." My doctor said it could be the depression but might be the Seroquel, so I went from 200 to 150 mg and it got mostly better. Am also on a lot of other meds so it's hard to tell but I think it was the Seroquel. It does help sleep, but I have to go to sleep when I take it or I will have racing heart, and will sometimes eat and eat until I pass out.

Hi, I've just had my Mirena taken out ( thank Heavens) and can now get my life back. The only good thing was no periods for five years. The hormones gradually ran through my system and all the side effects crept up on me.
My allergies got MUCH worse.
My skin thinned.
I felt three thousand years old , ALL the time.
It stripped a goodly amount of calcium from my body, my teeth started crumbling.
( after two months post removal, my bone and teeth density has improved out the site! WITHOUT supplements My dentist and doctor are now a lot happier)
I had NO sex drive at all.
My weight crept up with NO lifestyle change, 30 kilos! - I have lost on average half a kilo a week since removal. NO diet change, NO activity change.
I've always had slight hormonal acne on my face and nowhere else... with Mirena I had it all up my formerly crystal clear back and diarriere, bust and even scalp.
Lots of other minor crap.
Please, if you have sensitivities to the pill and other hormone treatments, DO NOT go here. I thought I was just aging rapidly- bull dust! I'm just glad that my husband gave me all the support I needed to bring this tragedy to my doctor and Gynie's attention. For so, long I thought it was just me.
Now I'm having my tubes clipped. Hormonal interference just doesn't work for me

After reading many of your experiences, I feel the urge to tell my story. I got my Mirena put in back in June 2007. My doctor had been encouraging me to try Mirena because I was having such problems with my periods while on the pill and I had tried different types and brands and nothing seemed to be helping me. So, finally after about 2 years of her telling me to try it, I did. Since I have not had children, she said I needed to have it put in while on my period so that my cervix was more open. I called her on the first day of my next period and got it put in. It was very painful to be inserted, and the horrible cramps lasted about 48 hours, but then went away. My period also got worse during that time, but then completely stopped two days later. I didn't get my period again until two weeks ago, which stunned to me. My doctor had said that I may have spotting the first couple months, but then that would stop and I would no longer get my period. Since it has been 6 months since I've had it, I thought it was very odd for me to suddenly be getting my period again. Along with the actual menstruation, I got the cramps, headache, bloating and everything else wonderful that comes along with a full blown period. I only had menstruation for 3 days (the shortest period of my life) but the cramps have continued constantly for the last 2 weeks. I decided I should look up the side effects of Mirena to make sure it wasn't abnormal. I got the same information from their website as I did from the pamphlet I'm sure we all got from our doctor - saying that only a very small percent of woman have any side effects at all. So, I thought I was making things up. But the more I thought about it, the more I realized all the things that have changed for me since I got it put in. That's when I stumbled across this site and found I'm not the only one and I'm not imagining all these things! I gained 30 lbs in the first 3 months - I blamed it on stress because we had just put our house on the market, however I had never in my life gained THAT much weight in such a short period of time. I am now over 200 lbs and I'm only 5'3". I have been desperately trying to take the weight off, but it won't budge and I'm only continuing to gain more. It is getting to the point where my weight is starting to cause other health concerns. Also, I have not had a single good night of sleep since I've had Mirena. I again blamed it on stress (but to be honest, I've lived through much more stressful times in my life without the tremendous weight gain and insomnia). After several weeks of trying OTC sleep aids, I went to my doctor and she gave me a 10 day supply of Ambien. The first 2-3 nights it helped, but then that also stopped working and I was back to sleepless nights. I found there is an herbal supplement that helps me sleep, but it only works for a few hours at a time, which obviously is better than nothing. I have also had cramps on and off throughout the last 6 months, sometimes they are very sharp stabbing pains that make me buckle over in two. I have also realized that I may be having depression - I don't feel suicidal, but I get very down very easily and stay that way for much longer than I ever have. I have actually had such horrible down days that I've called my husband at work crying and begged him to come home. I have never in my life done that until Mirena. I'm sure that I have more symptoms, but I have been able to persuade myself that they are "normal" or explained them away otherwise. I think that Mirena and the OBGYNs must be in cahoots. I was not warned about any of these problems - I was only given the small pamphlet and told it was so wonderful. I think there are a lot of other women out there experiencing all these side effects but their doctors are telling them it's normal or blaming it on something else. And they aren't realizing it is Mirena that is causing all these problems! I have an appointment for next Tuesday to get mine taken out and I cannot wait! I am finally going to be able to sleep again!