Irritability symptoms and conditions

I am 39 years old and work for an interventional cardiology medical device company in Tokyo, and so know the importance of controling one's cholesterol, keeping the LDL's low and the HDL's high. About two years ago, my doctor put me on 10 mg of Lipitor. Several months later I herniated a disc in my neck between C6&C7. From that point onward, I attributed all of my neck and back pain, and newly acquired total body muscle and joint pain, to the herniated disc, it made the most sense. Over the last seven months, I have really worked on my diet and began to exercise more (even though quite painful) and was able to lower my cholesterol. This resulted in my doctor lowering my Lipitor prescription from 10 mg to 5 mg. I noticed a slight alleviation of the pain I felt in my hip joints and calves. About two weeks ago I took myself off Lipitor completely and found further improvements in my total body muscle and joint pain. It's still there but greatly improved. In retrospect, I now believe the Lipitor may have been the culprit (or at least a contributing factor) to my herniated disc due to muscle degeneration in the neck, and all of the subsequent muscle pain, especially in my hips and calves. I fully understand I am not going to die from calf-pain, but may from heart disease. However, I have found my quality of life has improved tremendously over the last few weeks. Less irritability, better sleep, less pain, clearer head. I feel like I have lost two years of my life on Lipitor via personal suffering and lack of ability to do much of anything with my wife and two young daughters. We all need to take charge of our own health and therefore I encourage anyone who feels completely different after taking Lipitor to engage your physician, and make sure its the right option for you. If damage has been done to my musculature I hope I can reverse it. It is evident to me that some serious clinical studies should be done to investigate Lipitor's effect on muscle degradation and hope others will consider carefully whether or not do go on this drug. If you do, monitor yourself closely.

I am 25- been taking topamax for the last 2 weeks. I've already lost over 6lbs but have frequent diarrhea. My other side effects are: inability to concentrate and track (very bad as a therapist, poor clients...), irritability, and every carbonated drink is FLAT!!! I will see where this goes from here, if it keeps on its over and i'm done with this.

I just started my second month of Yaz, and this last week or so I have been experiencing side effects, such as; mood swings, irritability, loss of patience, sudden crying fits, and headaches. I think it is too soon to notice any weight change, but I am just not happy with myself. I have read through the posts, and I am happy that all of you have posted, but I haven't seen anyone talk about other options. I am wondering if anyone else has been given any recommendations. I have been on Yasmin in the past (high school, I am now 24), but never experienced these side effects before. The pill does clear up my mild acne, but only until I hit the last four pills. Not a concern of mine, I would rather not be so moody and irritated all of the time. Can these side effects happen so soon? I thought that it took longer for birth control to be in your system. Any comments back would be great. As of today, I am off Yaz, and have scheduled an appointment with my gynecologist to discuss further options.

I've had Mirena since Jan. 2006. This is what's going on with me.

EXTREMELY bloated all the time, diagnosed as IBS. I’ve tried everything: herbs, teas, diet changes, prescription meds (currently on anti-depressant (for the IBS, not depression) and an anti-spasmatic pill), and non-prescription meds (currently taking beano before every meal and gas-x after the beano has not worked!)

Irritability

Tired all the time

Not motivated to do anything

Forgetful

Loss of concentration, I have the attention span of a 3 year old it seems!

Heart fluttering and dizziness like a panic attack. The doctor actually said it was panic attacks but I honestly don’t feel “panicked” when they happen.

Fluttering in abdomen as if there were a baby in there

Sometimes feel a pulling or stinging sensation in my uterus

Hubby can feel the strings and we think they are irritating his manhood

A lot of these symptoms seem like depression but all praise be to God, I have a wonderful life. I have the greatest husband and kids I could ever ask for. I love our life. I’m not unhappy at all. I didn’t consider that it may be the Mirena until my husband mentioned that he thought the strings were causing the irritation on his penis. I started googling Mirena to see if anyone else had this problem and came up with so many “other” symptoms of Mirena. I thought “WOW!! Maybe THAT’S my problem!” Maybe it’s time to make that appointment to get it out.

I've had my Mirena out for nearly 2 weeks now, after 15 months of living with the side effects. I've posted before about fatigue, crankiness & irritability, low-grade depression, weight gain, poor sleep, headaches, etc -- same old story as everyone else -- that came on gradually over the months. I'm still SO grateful to this website for making it clear to me that this wasn't just typical exhaustion due to having 2 little kids (now 3yrs & 16mos) or post-natal depression. Anyway, getting the Mirena removed turned out to be an ordeal in itself -- the strings disappeared and the doctor couldn't see anything with a speculum, so I had to wait 3 weeks to get an ultrasound and it turned out to be in the right place (phew!). Then I had to wait nearly 2 months to have a hysteroscopy -- they dilate your cervix and poke a camera up inside your uterus so they can see where the coil is, then they can pull it out. The poking and prodding was a huge drag, uncomfortable but not excruciating. When they actually pulled it out it barely hurt at all. I was a bit sore for a day or two, like mild period pains but nothing serious.

So, here's the update so far: My sex drive came back the very next day after being completely gone for ages! That was such a nice feeling again, to actually want to be with my husband instead of just going along for the sake of the marriage! I haven't felt sick or achey in my joints since it came out either, and the headaches are pretty much gone after being a constant in my life. I'm sleeping easier, and generally feel healthy again -- such a relief! My energy levels are still really really low though; I sure hope they start to come back soon. I think it's going to take awhile since I'd pretty much stopped exercising due to feeling so ill and tired all the time. I'll have to build myself back up through eating better and getting back to the gym, so unfortunately I think the weight-gain and fatigue are going to take longer to 'cure'. But still, I'm so glad to have it out and know that whatever happens to my health now, at least it's not being caused by hormones that just don't belong there.

Hang in there everyone; and don't be afraid of the pain in having it removed.

My total cholesterol was 220 and LDL was 157; I started taking 40mg last week and within 2 days I just felt horrible. I felt weird and yuck in my stomach. There was a fog in my head and 2 days ago I was so dizzy I was almost falling over; I had to catch myself with the walls and doors. The next day, yesterday, I started having higher blood pressure and racing pulse with heart palpitations every 45 seconds or so, which makes me breathe deep often. I have felt pain in the back, arms, neck, and hips. I have also had weight gain and stomach irritability. Last night was the first night I did not take my medicine and even though I don't feel all that better I will see how it goes. I fought taking this medicine for over a year now and since my cholesterol went up I figured I'd try it in hopes my level would drop, but I can't handle this, I'm only 38!

This is my Mirena story. I got it inserted just over 4 months ago. Other birth controls were not working very well for me, as I had irregular bleeding with them often. So my doctor recommended Mirena. Insertino was awful. It hurt terribly. I almost passed out in the office from the pain (and I am not a wuss when it comes to pain). On the drive home I had to pull over to throw up - I was so nauseous from the pain. The extreme pain (which, to me, was worse than when I was in labor) lasted for a few days then subsided.

I bled for 30 days straight after insertion, which was awful. I also have experienced hair loss, acne, irritability and weight gain (without changing my diet and exercise levels). Over the past four months I have also had awful back pain and extreme cramps that seem to come randomly. My periods come and last 10 days.

Recently, I decided that I'd had it with the Mirena. I went to the doctor today and had it removed. After talking with her about my side effects, she was very supportive in my decision to have it removed. She believes I may be overly sensitive to the progestin in it. Removal was super-quick and easy and virtually painless. I'm looking forward to life without this thing!

I have been on Methotrexate for about 1 year to treat RA. It has worked great for pain BUT I have noticed a lot of things going on that I've simply contributed to life. I have severe headaches, dizziness, extreme fatigue and major mood swings (depression and anxiety). I've seen some things posted on the internet about these being side effects. I am going to talk to my RA doctor and see if there is something we can do. I have been so bothered by these symptoms that I would just about prefer the pain to the constant feelings of irritability and depression. What are some other medications people are finding useful of RA with out the side effects????

I was taking 20 MG of Lisinopril for approximately 1 month, getting a bp reading of about 155/95, so my doctor increased the dosage to 40 MG. About 2 weeks after that, my BP is up a lot, to about 190-200/95-110. Anyone have a similar reaction?

I have had Mirena put in Feb 09, so it has been 8 months and for 7months I have had a yeast infection that wont go away. It gets really bad the week before my period and the week after its not too bad. I have used OTC drugs and prescriptions. I have never had a YI before I had the mirena. I do believe it is the reason I have one, so I am going to get it removed. I have also been very tired and foggy feeling and never made that connection until reading all these posts.

I was taking Lamictal for 2 years. I was diagnosed with a "light" case of bi-polar. Not the highs, only the lows. I am not too sure that I wasn't just going through some really rough times in my life and had had enough. Couldn't take the stress. Anyway at first I had dry mouth, bad constipation, belching in the evenings and lots of it, some female itching and similar issues (sorry but just want to help here), couldn't handle any alcohol, loss of hair, problems sleeping, outbursts of anger towards mate and irritability, aggressiveness at time, loss of memory and loss of concentration, scatteredness, lots of hair loss and sensitivity to sun. I wanted to be a trooper and make my psychiatrist happy so stayed on it. I got lots of good things from it, like can roll with the punches of life better, can really easily speak up for myself and defend myself when I need to. Don't beat myself up like I used to. So, lost some of the sensitivity that I needed to lose but can't do without my memory. It had been so bad that friends and family would comment and I was embarrassed. Also, my mate shouldn't have had to deal with some of the rage that would show up when things were taken wrong. Oh, I had one of the strongest panic attacks that I can imagine a person living through. I had never had one before, and haven't had one since. I stopped this drug cold turkey. It felt like a few weeks of jet lag. Take multi-vitamins and minerals, also fish oils. Only the highest quality. Eat really healthy, exercise, drink lots of water and rest a lot...whatever you do, don't stress out if you are coming off of this drug. This is actually a very useful medication, however, in my opinion it needs to have more research done about it.

I've got to say that Mirena makes my hair very thick, and I have lost weight, not gained it...and I LOVE not having periods.

I have had mood swings, irritability, and stomach issues since having it installed in July'07 but no other problems what so ever, until a few months ago...ever since May'09 I have had nausea, extreme loss of appetite, and breakouts(very out of character for me). My husband had a vasectomy in May, and I plan on getting the Mirena removed next month. The ongoing irritability is definitely the biggest problem for me...it makes me very short tempered with my children.

I don't know why the new symptoms started a few months ago...maybe some kind of hormonal buildup...I am very sensitive to birth control usually, and Mirena has served its purpose well, but now I am ready to move on.

I think Mirena is like any birth control, it works well for some people and not at all well for others. I do not think it is awful, or terrible or anything like that...it just has to be the right fit, and all drugs have side effects. Good luck ladies!!

Had my mirena removed yesterday after spending the weekend in the hospital for "cardiac telemetry" (observation). This was my 2nd major event this year that made me feel as if I were in need of immediate medical attention. I have had too many days of dealing with "cloudiness", blurred vision, headaches, waking with body aches, abdominal "flutters", irritability, chest pain, numbness/weakness/tingling in arms and legs, thinning hair, and horrific weight gain! The sad thing is that I didn't realize all these things had a single culprit until the end of my 5 years. I'm just glad that it is out, and I have brighter days ahead!

Tearful within hours of inserting the ring. Since, a constant sense of dread; dark thoughts, foggy, sluggish thinking, no motivation (and I'm a go-getter in a highly competitive profession), contact lens intolerance/changes in vision, vaginal dryness (UGH!!) irritability, fatigue, flu-like aches and pains with chills from time to time. Puffy like the Michelin Man. Yuck. Just threw the damned thing in the trash and couldn't be happier. Paragard, here I come. No more synthetic hormones for me. I quit.

A constant sense of dread; dark thoughts, foggy, sluggish thinking, no motivation (and I'm a go-getter in a highly competitive profession), contact lens intolerance/changes in vision, vaginal dryness (UGH!!) irritability, fatigue, flu-like aches and pains with chills from time to time. Puffy like the Michelin Man. Yuck. Just threw the damned thing in the trash and couldn't be happier. Paragard, here I come. No more synthetic hormones for me. I quit.

I have only been taking Yaz for a week, but noticed the negative side-effects almost immediately. I am on a steady regimen of anti-depressants and couldn’t understand the sudden on set of mood-swings (extreme anger, irritability, sadness, lack of interest, flat-mood, etc.). Also, I have been very fatigued (wanting to sleep 14-16 hours a day).

I am contacting my physician in the morning, but doubt I will continue taking this medication.

I do not recommend Yaz to any woman currently taking prescription anti-depressants.

Within 12 hours of my first dose, I started experiencing irritability, racing of thoughts, rapid heart beat, shortness of breath, nausea, sweating, and then ultimately, a panic attack. I have history of successfully treated depression from several years ago, yet this med brought forth all those painful old feelings of angst. I am discontinuing doxy immediately. I wish that one of the warning labels on the Rx bottle read, "Do not take if there is a history of depression." It sounds like that would have save a lot of people a lot of grief. Best wishes to all for good health.

I was on Singulair while pregnant because my asthma got worse while pregnant. Postpartum I noticed my 2 month old breastfed baby was still sleeping way too much and very colicky. I tried cutting out dairy and other allergens but nothing made a difference. When I forgot to take my Singulair a couple days in a row, I noticed my mood was much improved and the anger/irritability went away. Finally, after noticing I was having vivid, bad dreams, I began to realize it might be all from the Singulair. I also had developed a stiff, tight neck and vision loss, which I now realize was also from being on Singulair.
I went off of it and must say, that was the worst week of my life. I never felt so horrible or out of control. Although I noticed the first few days, I was happy and feeling again (it made me emotionally numb) by the fourth day, I began having heart palpitations and bad headaches. I quickly got my thyroid levels checked and those were fine. Then I suddenly had severe panic attacks! I thought I was going crazy! This was mistakenly misdiagnosed as PPD, although I was never even depressed. I was given a script for Zoloft and took Ativan but that didn't take away the panic and the Zoloft seemed to make the panic worse!
I began researching and realized all of my symptoms were from Singulair withdrawals! Even my family noticed I became a mean and hateful person with this last pregnancy. This drug is an awful poison! I am slowly recovering and feeling better everyday. I'm using my fast acting inhaler for the time being. Instead of the therapy I thought I needed for PPD (mis dx'd obviously) I'm also using herbs to treat this homeopathically with a natural doctor since conventional ones still want to pass it off as something it is not due to ignorance that an asthma medicine can wreck this kind of havoc on a person! They just want to use more drugs to treat the side effects of another drug!
I am so angry I took this while pregnant and breastfeeding being told it was okay. It was not okay and I hope and pray there are no long term side effects to my child from this drug!

I've been on Losetrin 24 Fe for about a month and a week.
I've noticed some irritability, nausea, shortness of breath, bloating, and increase in acne. I had sex with my boyfriend after taking the pill for a little over two weeks, he didn't ejaculate inside of me, but I missed my period when it was supposed to come, and instead I just had about two days of really light spotting. I feel bloated constantly and get a little nauseous after eating. I've also had a serious lack of energy. No weight gain, or anything else. Bu the missed period thing freaks me out, and the ache just stresses me out more.

I have been on Mirena since September of 2006 (6 weeks after my youngest was born). I can't ever remember to take the pill, I've always had really heavy (super tampon and overnight maxi) periods for 7 days with really bad cramps, and I'm not sure if I want any more children. I had seen the commercials, read about it, and decided this was what I wanted. Well during the settling period (about 9 months - 1 year) I experienced the cramps, bleeding and bloatedness. However I've now had it for three years with no problems, that I thought anyways... until this month. I haven't had a real period (other than spotting for three days or so) for over two years now. Well this month I started spotting and didn't think anything of it. Then it slowly got worse. Luckily I had an appointment with my Dr. coming up (this past Monday), so I figured I'd talk to her about it then. Well, when she checked she said that it looked like the Mirena had come down a bit, as the strings were several inches longer than they were on my last visit. She has now scheduled me for an ultrasound this Friday to see if they can find out what's going on. It's been two weeks since the bleeding started, and just as I think it's gonna stop, it gets heavy again and I pass more clots. After reading everyone's posts, I'm a little scared. I start to think about how I've been over the past couple years and wonder if maybe some of my moodiness and irritability has been because of this little thing. I'm usually one of the most laid back people, but I do tend to snap at my children and boyfriend a lot. I know now that I also have the side effect of the lack of sex drive. I had trumped that up to having a little one, but that's probably not really the case. I hope I will find out more tomorrow. Just on another note, my boss also had Mirena put in. I'm not sure that she had any side effects, because she never mentioned any to me, except about the discharge because we both had that. Anyways, she had hers out in March and she just found out she is pregnant (but only a few weeks along).. but she's been bleeding, so she's going in twice a week to make sure her levels keep going up. Anyways, I wasn't aware that the way Mirena worked was just by self aborting the embryos. I don't like that idea at all, so after I figure out what's going on with me, I need to really sit down and weigh all my options because right now my side-effects aren't near as bad as anyone elses on here. Anyone know of another IUD that doesn't have the side effects like this one?

This web page is a revelation. I thought I was the only one!! Was put on Yasmin by my Gynae for slight hormone imbalance (with no symptoms). Been on this pill for 4 yrs. Never had Pre Menstrual Tension until I took this pill. During my period, I suffer horrendous migraines, nausea and irritability and waves of anxiety for 3 days and then it goes.
Went to see another Gynae who said these headaches and bizarre side effects appear to be quite common with Yasmin and has recommended me take another one and won't recommend Yasmin to any of her patients anymore!

RB UK

SINGULAIR'S LABEL HAS BEEN UPDATED:

The following has been added to the "Precautions" section of Singulair's label:

"Neuropsychiatric Events
Neuropsychiatric events have been reported in adult, adolescent, and pediatric patients taking SINGULAIR. Post-marketing reports with SINGULAIR use include agitation, aggressive behavior or hostility, anxiousness, depression, dream abnormalities, hallucinations, insomnia, irritability, restlessness, somnambulism, suicidal thinking and behavior (including suicide), and tremor. The clinical details of some post-marketing reports involving SINGULAIR appear consistent with a drug-induced effect.

Patients and prescribes should be alert for neuropsychiatric events. Patients should be instructed to notify their prescribe if these changes occur. Prescribes should carefully evaluate the risks and benefits of continuing treatment with SINGULAIR if such events occur (see ADVERSE REACTIONS, Post- Marketing Experience)."

Our son, who is now 6 was prescribed Singulair at the age of 3 due to asthma/allergies. He was prescribed this by an ENT/Allergist. I thought our sons mood swings were due to the fact that we were expecting another child. He was always so happy/loving and playful. When the baby arrived 2 months later, his behavior worsened. Again, I put it on the new baby sister in the house. His moods/anger/outbursts increased. He hit, threw things etc. I told the doc about this and he said it was due to his enlarged tonsils, and they were then removed. Well needless to say, his behavior did not change because he was still on the Singulair. I mentioned the possible side effects to his pediatrician and she said it was a possibility, but to keep him on it because he needed it. Well, 3 years later, in March of this year I took him to an allergist that I had seen years ago. He immediately took him off the singulair (and all inhalers). His moods seemed to brighten a bit, but not they are worsening again. Is it possible for the Singulair to have long term damaging effects. I understand kids have tantrums, etc. Kids are kids, I get that. But he punches, kicks, screams, cries etc. My husband are at a loss. We don't know what to do. Oh, and he is now on Veramyst as needed (march-june, Aug-Oct.). Has anyone else experienced long term effects due to Singulair?

So I'm back again to update you all since I've removed my mirena myself on Monday night and started my period this morning. So far everything seems to be going normal. I have lower back pain slight tenderness in my lower abdomen and some irritability. The bleeding is medium which I consider normal. I do have some slight joint pain, but I believe it's only from the bleeding as I didn't have it yesterday the day after removal. All on all so far so good. I hope it just continues to get better in time!!

This is the biggest relief. I am sure you can all relate finding this website. I started using the nuvaring back in February and the side effects started soon after, I just haven't tied it to the birth control until now. The first month I started using it I was planning to move from my home in boise to Orlando Florida to live with my boyfriend.. which is very stressful so needless to say my high anxiety stress irritability and anger all seemed to be pointing to the stress of moving from my home although it is what i wanted it was still scary. I have been here in Florida for 3 months now and still experience the same things adding one to the mix as living with your boyfriend should spark an instant sex drive when you haven't been living in the same city for a year. NOPE no sex drive at all. Maybe once in a blue moon i get in the mood but i literally have to talk myself into it which is pathetic. There are times when i am laying next to him and i have to tell myself if he wants i should go along with it. but though of sex just drives me away. Also the depression is unbearable I am a very happy goofy person and it is a struggle to keep my temper in check or to try and work up motivation to leave bed. I am constantly tired and have no drive to accomplish anything anymore which is out of my character.
Headaches I have always had and migraines i have had before the nuvaring about once a week now i have migraines at least 3 times a week and a headache every day in between. My breasts have been extremely sore so much that i thought maybe i was pregnant in combination with my extreme mood swings. I have thick hair and i shed a lot never thought that it may be due to the birth control. I am getting somewhat angry that this is the way we all have to find out. It is frustrating to feel like a crazy person and wonder what happened to the person i use to be. I have not experience any weight gain fortunately, but since have no motivation i am not in the shape i once was because i have no desire to go to the gym.
The itching sensation i didn't realize as a symptom before reading others stories. Now it is so clear how aggravating. One month my cramps were so bad and a couple of months in a row i felt so nauseous that i would get sick. One time i was driving to a friends house when all of the sudden i knew i was going to be sick and ended up vomiting all over myself... so embarrassing and i couldn't figure out what happened. Tomorrow morning im calling my doctor to see what we can do. This is my last day with the Nuvaring Thank god for this site and thanks to you all sharing your stories it brought me peace of mind knowing ill be myself again soon.