Knuckles symptoms and conditions

Joint pain in fingers, joint pain in knuckles, wrist weakness after a week on 10 mg daily dose of Zetia. Amazing reduction in bad cholesterol and triglycerides when used with daily maximum 80 mg dose. Zetia was discontinued because of these painful side effects. 68 year old male.

On Doxycycline 100mg twice a day for 12 days then 200mg twice a day for 12 days for very-likely Lyme Dz (fever, hip rash) apparently diagnosed in the first month of infection. First few days on Doxy I had a lot of esophageal spasms (kind of a cramping in the middle of the chest), but those subsided.

About the time I was finishing the 24 day course of Doxy, got red-violet itchy rash of both hands just over the lower knuckles (where the fingers meet the hands) after a long drive - unsure of sun exposure. Just walking in the sun for a few minutes sets it off. Little improved now 6 days off the Doxy. I'm a doc and first wondered if it was a sign of dermatologists - a pretty bad disease that includes a knuckle rash and muscle breakdown and is sometimes related to Lyme or cancers! It was very reassuring to read all the patient prior reports here of very similar problems on Doxycycline. This is a great site and glad to contribute to it with my story.

I feel so relieved to have found this website. I am going to call the doctor and have my Mirena removed ASAP! I have been experiencing many different random health problems lately. Which is strange because I am an extremely healthy person. My husband was laid off from his job and we lost his health insurance, so through all my symptoms I have just been suffering through it because I couldn't afford to go to a million doctors and have a million different tests run to find out the source of my symptoms. It started with itchy hives on all of my joints, elbows, knees, knuckles, toes and fingers. Then a symptom I had gotten during my pregnancies called PUPPP which is basically ugly, little, red bumps that ooze a clear liquid and itch like the dickens on my hands, fingers and legs. Then a big knot developed under the skin on my right wrist. The pain started on top and started radiating all the way around my wrist. Then the numbness, tightness and pin-prick pain occurred in my fingertips, then my hand, then my entire arm went numb from the elbow down. I also had horrible pain in my reproductive area on two different occasions that had me doubled over in pain. It felt exactly like contractions. I also have been bleeding every day for several months. Not enough to call it a full blown period, but bleeding every day. Some days, blood streaked mucus, other days full on blood clots would drain out of me. I've has horrible back pain and have been very fatigued even when I am careful to take care of myself. I also am naturally a very optimistic person who can handle bumps in the road of life, but lately, even though I hate to admit it, I have been down-right depressed. I have lost interest in all my interests, have a hard time shaking off life's set-backs, find myself on the verge of tears a lot, and basically have just wanted to pull the covers over my head and not wake up until I can just feel like myself again. Then last night my lips started to tingle, numb and swell. Then the same thing happened again tonight. I told my husband I am just falling apart and don't know what's wrong with me! I have never had any health problems before and now it's a new symptom practically daily. He said he had been doing some research and that he thought I was allergic to my IUD. I immediately Googled "Allergic reactions + Mirena" and found this website. It is such a relief to know that I might actually have an answer to all my problems. I can hardly wait for the doctor's office to open in the morning, I want this thing out right now and I want my life and ME back!

This is the second time i'm writing on here. I posted my Mirena side effects a few months ago and thought i'd update my side effects....

before i had the mirena put in i was doing GREAT losing weight right after my 4th baby. i actually lost 15 lbs and weighed less then when i got preggo. within a 3 week period of getting the Mirena put in, i gained 11 lbs! and my dieting and exercise wasn't doing much good. my doc recommended that i watch was a eat a little more carefully and exercise MORE.... how much more do i have to watch was i eat and exercise?? anyhow, its been almost 6 1/2 months since i had it up it and im just experiencing more and more side effects. now i had what looks like a really bad case of eczema all over my body. especially on my knees, elbows and my knuckles. my scalp is really itchy, i've GAINED 30 lbs, my hair is falling out like crazy, by bones are killing me especially my lower back, ankles and shins, my mood swings are horrible i feel like im PMSing all the time and when i get my period which is still messed up and lasts for 2 weeks i get even moodier! i am always really tired, i feel like my chest is about to explode, whenever i eat i get really nauseous, i feel depressed all the time and have bouts of crying spells.... i've always had migraines but the mirena seemed to make them EVEN WORSE now. IDK, i've just about had it with the IUD. the only good thing about it is...im not pregnant!! and i don't understand why doctors keep brushing all these symptoms off as if we are all crazy when we say we are experiencing something that we know wasn't there before the IUD...

Have been on Welchol for IBS for many years. It stopped my IBS symptoms but does cause constipation. I try to eat healthier in order to help with that. About 3 months ago, I began having pain in my fingers. I thought it was probably due to carpal tunnel syndrome. In the last two weeks, the pain intensified and spread to all the knuckles on my hand; I also had swelling and redness. The pain then spread to my toes, the rest of the bones in my feet, wrists, elbows, shoulders, knees, and ankles. Next came stinging and burning and then sporadic numbness. By late afternoon, the fatigue was incredible, and I would become dizzy. I went to the doctor, and he ran every blood test available. Everything came back normal, which was great, but my doctor couldn't pinpoint what was causing my problems. He said none of my medicines would cause such symptoms.

My boss asked me if I was taking any cholesterol medication, and I told her I took Welchol for IBS. She said she had read article upon article connecting cholesterol medication to joint paint and encouraged me to check online to see if I could find any answers. This site was one of the many I found where other people mentioned symptoms very similar to my own. My boss suggested I mention this to my doctor. I was thrilled at the prospect of finding such an "easy" solution since my other medications are not easily replaced.

My doctor instantly said that there was "no way" that Welchol could cause these symptoms since -- as so many of your doctors have told you -- that it is not absorbed into the bloodstream. However, he approved my stopping Welchol as an "experiment". I noticed that many of you mentioned it took a few weeks or more for the symptoms to reduce. My doctor warned me again that this was not the solution and that in a couple days, he wants me to consider taking Neurontin or going on a sedative for stress. He thinks, since all the tests have come back negative, that stress is the real culprit.

I know that stress can cause many health problems, but it just seems too coincidental that so many of you have experienced the same symptoms I'm facing. Do you think I'm making the right decision? My symptoms are difficult to cope with at times, but they are not incapacitating. I would really like to try staying off of Welchol and see if it helps in the weeks to come instead of adding yet another medication to my list.

I would appreciate your advice and thoughts. Thank you for your posts -- they have given me real hope for a solution.

I am so glad I found this site...have been on doxycycline for about a week and spent about 30 minutes in the sun...oops! my toes and knuckles on my hands feel like they are on fire constantly. They are red and swollen. They burn just sitting here! Is there anything that can be done to help? I quit taking the medication. I was on it for acne treatment, but decided I will live with it rather than deal with the pain of sunburned feet and hands!

I was just prescribed Lisinopril 10 mg about 3 weeks ago. I now have severe pain in my muscles in my butt....yeah my butt and really bad joint pain in my knuckles..I thought it might be arthritis, but now I guess it is all due to this med. which I will be stopping as well. Does anyone have a natural/homeopathic way to decrease blood pressure? I know the Chinese and jungle people have been using nature to cure themselves for thousands of years and I am going that route now once I find it.

I'm 27 years old and finally admitted to myself that I am depressed. My doctor put me on Wellbutrin XL. 150mg for the first week then 300mg ever since. My first week on 300mg I was extremely anxious, shaky, tightness in chest, couldn't sleep for days, etc. I started to split up my does. I took one pill in the morning and one about 5pm. This helped a lot. By week three I felt wonderful and decided to go back to taking both pills at the same time. Again, I felt great. By the Friday of my 3rd week, I began having hives like crazy. I have been living on Benadryl and Ibuprofen for the pain. Today is day 3 of hives and I am once again plastered. I also have extreme pain in my feet, to the point where I can barely walk. My hands (knuckles) and my knees are also tight and sore, but no where's as bad as my feet. I believe that my body may be very sensitive to this drug now. I have experienced just about every other side effect, but I pushed through it and they went away. Wellbutrin has been amazing for my mood and I am very sad at the thought that I may have to go off of it. Are the hives something that I can just push through or is the inevitable about to happen and I will be forced to stop using this drug?

8 weeks on januvia,headaches, muscle pain weakness in thighs,flu like symptoms in sinuses and chest! Rash/raw areas on knuckles! Stopped taking medication and all symptoms improved within 3 days.

im 17 yrs old an on these tablets for depression. although it has cured my depression iv started gaining weight my appetite has changed all i want to do is eat. i don't sleep properly. i haven't had a good night sleep yet im tired all day my legs shake at times . i have some anxiety an i seem 2 be really loud all the time. i am also a kickboxer an the medication seems 2 make me really agitated and angry an im really worried someone is going to piss me off an im gonna do something really stupid and im scared of myself. my uncontoled rage makes me hit walls all the time an my knuckles r all scared im scared of hurting people an the look on there face when i get angry. i get thoughts in my head to kill at times.

My son has been on Concerta 54 for 2 years now. His grades have drastically increased and his attitude is great while he os on the meds. I do notice that he comes down from the meds in about 8 hours and his relapse is not fun. He becomes extremely emotional and violent. He will cry at the drop of a hat when things do not go his way. He also wants things to perfection. I also notices he picked up some bad ticks like popping his knuckles or clearing his throat. He is very negative when he comes down from the meds and has a hard time falling asleep.

Started a 5 day 750mg Leva-pak on Sunday after amoxicillin didn't touch my bacterial throat infection of unknown origin. My husband mentioned these boards full of complaints, but I was so miserable that I said I would be fine--never had a problem with a drug before.

Sunday brought swollen, painful knuckles. Monday had palpitations and painful sensitivity to light. Tuesday night I was wired and couldn't sleep at all, my heart was racing, and I had asthmatic wheezing and serious shortness of breath and borrowed my husband's inhaler. The pharmacy said insomnia wasn't a side-effect (which was misinformation) and I'd be fine as long as I didn't have a rash (more misinformation). I was finally feeling on the mend as the fever had broken Tue night and I attributed the symptoms to the infection. Then I took my next dose of levaquin.

Within 10 minutes of taking it, I was considering a trip to the ER. My head was splitting, I was extremely sensitive to the slightest motion, sound, or light, my heart was racing again, and I felt violently ill to my stomach all within 30 minutes. My throat swelled to the point I could hardly breathe or swallow my spit. My temp that had been normal since the early morning hours also shot up to 101. It was so drastic and sudden that there is no possibility the symptoms came from anything but the medicine. Short of contracting anthrax, I won't ever take this again.

AND my throat is worse! They put me on augmenting now. Wish I'd gone on it in the first place.

took Levaquin 500mg x 5 days end of March ,2008- no problems except still with bronchitis sx.Saw Allergist who said not enough,long enough-put on 750mg x 21 days, again no side effects and got better. after 5 days off, started productive cough so placed on another 16 days of 750mg. On day 13, awoke with terrible pain in knuckles, knee. Completed med as drug book only listed tendon pain not joint pain. Now 4 days after completing, pain in elbows as well as knees, less in knuckles. None of joint pain sx listed on Pharmacy info either.

I have been taking Doxycycline for 10 days. I noticed on about the 4th day that any sun exposure was painful and also the hands tingling and even burning. But the weirdest of all is the effect water has on my hands. It will cause them to burn and will even turn red on the knuckles. This is painful.This scared me as the doctor didn't go over this with me and I am new to Doxycycline. Thank God today is my last day.

My beautiful 11 year old daughter was on Adderall XR 20 mg per day for 4 years. After about 2 years she started to develop some minor facial tics. After 3 years the facial tics were worse along with severe head shaking and she also started to develop trichotillomania (obsessive compulsive hair pulling). The hair pulling continued until she was almost bald. Her grades began to drop and she withdrew herself from her friends and family. Finally, we took her off the medication in October 2007 at age 12 and she immediately stopped the tics and hair pulling. We have found 3 other families whose daughters have developed these same symptoms after being on this medication for at least 2 years. We have filed a report with the FDA as our own doctor had no idea that this medication was causing the hair pulling. Now 5 months later her hair is growing and the tics are approximately 97% gone. We have taken her to a homeopathic doctor and she is doing absolutely great now. Marks have gone up and she is smiling and socializing. I am so happy we have our daughter back. The side effects of this drug was definitely not work it.

I started taking Levaquin last Friday ( the 11th) for a severe sinus infection. I was prescribed 750 mg for 5 days. I finished that but my sinus infection didn't improve so I was prescribed another 5 days of 750 mg. I took the pill yesterday and today ( totally 7 pills) I noticed on about day 2 or 3 that my legs felt tight, but thought it was a normal side effect. Then my lower back. I wasn't in serious pain at all so I ignored it. Today my knees, knuckles, shoulders, elbows, are extremely sore and i get sharp pains every now and then. It also hurts to sit for too long. I started researching the drug and now am so terrified after reading all these horror stories. Has anyone had this only last while taking it and not for months afterwards? Or am I pretty much in this for the long haul. And to the people who say that it lasts for months or years is it pain that disables you from working and doing daily things? I'm only 23 and I live a very active life and I'm totally freaked out now. PLEASE HELP

After using Osteo Bi-Flex with MSM for only 2 days and not changing anything else in my life, I broke out with a rash and persistent itching around my knuckles, wrists, elbows, knees, and feet. A spot on my right wrist swelled to the size of a siler dollar.

I am having tingling burning sensation in my feet, legs and hands and arms. My blood pressure was not improving on 5 mg so I upped it to 10 and those symptoms are much worse. The tingling sensation goes all the way up my left arm and up above my knees on my legs.

I have tried to take the Lisinipril before and stopped for these same reasons. My doctor does not seem to think that it is due to the Lisinipril. so I tried it again and the burning, burning sensation is driving me crazy and keeping me awake. I have to get up and stand in cold water for a while to get some relief.

I have not read about anyone with the same symptoms. Does anyone out there have these symptoms??

I was on it for about two months and experienced a little of the upset stomach. The worst was the sunburn on my nose, hands, knuckles and tops of my toes. And the tingling sensation on my hands was so weird! My nose and hands have healed, but the tops of my toes are still bad (one month later!!) I'm really scared, but one of my docs say that toes take a really long time to heal because of poor circulation. Anyone have this problem with their toes?? Another doc suspects discoid lupus. yikes!

My dermatologist put me on Doxycycline for an acne problem. By the first or second day of taking the medication I was overwhelmed with nausea and experienced blurred vision that affected me so much I actually had to pull over when driving (around day three) until I regained my vision. The only way I could dull the nausea was by eating a moderately large meal before taking a pill, but it would still take about an hour to an hour and a half for the feeling to pass. I also had trouble breathing and swallowing for the first few days, and a persistent loss of appetite during the entire period I was on the pills. During the time I was taking Doxycycline, I also experienced a groggy, confused feeling that is uncharacteristic of me. I had trouble focusing, which caused me a great deal of stress at work and in school, and couldn't think clearly at all. I also experienced tingling sensations and my skin burned/itched after hardly 15-20 minutes in the sun. After returning inside the redness gradually went away but tingling in my hands (especially my knuckles and fingers) and lips was persistent. Also, after being off of the pills for a few days I experienced extreme irritability and depression. In my opinion, this pill should NOT be prescribed lightly!!! Be warned!

I have been on Wellbutrin for two weeks. About four days ago I began having joint pain and swelling in just my left hand, middle and ring finger knuckles. It is swollen and getting worse, not better. Has anyone experienced joint pain in just a specific area and not all over with Wellbutrin?

I took doxycyline for 18 days, 100mg 2x/day for a skin infection. Immediately I realized how rough the drug was on my stomach, but I was able to overcome the nausea, etc. by how much I ate before I took the dose. My infection began healing very soon after starting the drug, and I was happy about that.

The side affects took a while to become apparent. Things started to get strange, little by little. I've never had heartburn until taking this drug. The sun sensitivity was not to be taken lightly. I even got a sunburn on my hands and knuckles. After the burn healed, I thought my hands were tingling as a result, but it seemed odd that they didn't stop. I was irregular and kept thinking that I had gained weight, though the scale showed no gain. All the weight gain issues turned out to be (gas) bloating that ended up being pretty extreme. The dr. said the drug probably attacked the "friendly flora" in my digestive tract. The yeast infection confirmed that theory. I also had moments of complete idiocy - really weird ones unlike anything I could attribute to lack of sleep or other normal causes of confusion. I also felt depressed during the last week on the drug. Because the side effects seemed unrelated to each other and all happened gradually, it took a while to attribute them to the antibiotic.
I finally stopped taking the drug when the syptoms sort of peaked.

I've been off the drug for 5 days, and my digestion is 75% back to normal, with huge doses of simethicon and acidophilous. My yeast infection is gone (post-treatment), and my hands are back to normal. But I am still depressed. The depression seems to have deepened since stopping the drug.

Did any of you have to be treated for your doxycycline-related depression, or did it just pass like the other side effects?

I started taking Dox. because I lost my baby.. and my doc. prescribed it to me so i wouldn't get an infection. Im only supposed to take it for ten days.. its day seven and I have this burning sensation that is on my hands.. My hands are all red where its burning me.. The odd thing is it started with my knuckles.. and now it has spread. The weird part is that Its only on the tops of my hands..
I talked to my Pharmasist.. and he said that it was a rare side effect..
I have never heard of an ANTIBODIC that would make your hands burn..
I stopped taking it because my hands are litterally on fire..
If anyone else has gone through this please tell me what you have done to get them to stop burning..
I tried Aloe.. and it worked for ten minutes.. cold water makes it worse along with hot water.. putting pressure helps for a few seconds.. the only releif that I have found is blowing cool air on them..

I've been on Topamax twice now for migraines. I went off of it the first time b/c I didn't think the side effects were worth it. As soon as I stopped taking it... my migraines came back. Now I'm on Topamaz again... and I can't decide what's worse.. the medicine or the migraines... especially after reading all of this. And what's really interesting... is that the second time around my side effects are different and I'm taking the same dose! I can drink carbonated beverages this time (which I couldn't do before), but I'm experiencing a lot of neck pain. And I have very sore, swollen knuckles this time. Mine are red and have strange bumps on them. Has anyone else had this???

I was on 10 mg. of lisinopril for about 2 months when I noticed that my left foot and my left hand frequently felt heavy, as if they had fallen asleep. My PCP checked me out and confirmed that I was not having heart problems. Then, I also experienced the "buzzing" sensation in my left hand and left foot. This happened frequently while I was taking the drug. I also experienced a burning sensation in the fingertips on my left hand and the muscles in my left arm ached.

Finally, I stopped taking the medication about four weeks ago and the sensations in my hand and foot greatly subsided, athough they did not go away completely. Ironically, a week after stopping the medication, I developed the achy joints (hand, knees and elbows) that many of you have complained about. Now, four weeks later, all symptoms have lessend substantially. I occasionally get a transient achiness in my knuckles and occasionally I feel some of the strange sensations in my left hand that I have listed above.

I just wanted to let those of you that are experiencing strange neurological reactions to this drug know that you are not alone; I went through what you are going through and possibly more and endured some of the worst weeks that I have ever experienced in my whole life; For weeks I was gripped by the fear that I was developing lupus or MS.

So, if you are struggling with some of these problems, be brave and stand up to your PCP and tell her that you WILL NOT take this drug anymore. I'm sure that you will find as I have that quitting lisinopril will restore your sanity and hope of having a happy, healthy future.