Ldl symptoms and conditions

I am 39 years old and work for an interventional cardiology medical device company in Tokyo, and so know the importance of controling one's cholesterol, keeping the LDL's low and the HDL's high. About two years ago, my doctor put me on 10 mg of Lipitor. Several months later I herniated a disc in my neck between C6&C7. From that point onward, I attributed all of my neck and back pain, and newly acquired total body muscle and joint pain, to the herniated disc, it made the most sense. Over the last seven months, I have really worked on my diet and began to exercise more (even though quite painful) and was able to lower my cholesterol. This resulted in my doctor lowering my Lipitor prescription from 10 mg to 5 mg. I noticed a slight alleviation of the pain I felt in my hip joints and calves. About two weeks ago I took myself off Lipitor completely and found further improvements in my total body muscle and joint pain. It's still there but greatly imporved. In retrospect, I now believe the Lipitor may have been the culprit (or at least a contributing factor) to my herniated disc due to muscle degeneration in the neck, and all of the subsequent muscle pain, especially in my hips and calves. I fully understand I am not going to die from calf-pain, but may from heart disease. However, I have found my quality of life has improved tremendously over the last few weeks. Less irritability, better sleep, less pain, clearer head. I feel like I have lost two years of my life on Lipitor via personal suffering and lack of ability to do much of anything with my wife and two young daughters. We all need to take charge of our own health and therefore I encourage anyone who feels completely different after taking Lipitor to engage your physician, and make sure its the right option for you. If damage has been done to my musculature I hope I can reverse it. It is evident to me that some serious clinical studies should be done to investigate Lipitor's effect on muscle degredation and hope others will consider carefully whether or not do go on this drug. If you do, monitor yourself closely.

My total cholesterol was 220 and LDL was 157; I started taking 40mg last week and within 2 days I just felt horrible. I felt weird and yuck in my stomach. There was a fog in my head and 2 days ago I was so dizzy I was almost falling over; I had to catch myself with the walls and doors. The next day, yesterday, I started having higher blood pressure and racing pulse with heart palpitations every 45 seconds or so, which makes me breathe deep often. I have felt pain in the back, arms, neck, and hips. I have also had weight gain and stomach irritability. Last night was the first night I did not take my medicine and even though I don't feel all that better I will see how it goes. I fought taking this medicine for over a year now and since my cholesterol went up I figured I'd try it in hopes my level would drop, but I can't handle this, I'm only 38!

I am 50 years old. Two years ago was diagnosed with very high LDL and low HDL. I told my doctor then that I did not want to go on statin drugs, but 3 months of Niaspan didn't help the cholesterol, and I hated the hot flashes and flushing that could come at any time after taking a dose. So my doc put my on Zocor.

Two years later I my bad cholesterol is within normal limits but my good cholesterol is still too low, even with fish oil and borage oil taken regularly. Almost immediately after starting the Zocor I started experiencing light-headedness and dizziness that would last for up to a minute--even lying down in bed! My doctor prescribed Meclizine for the dizzy spells--more stinking drugs! I get migraines at least twice a month. For the last six months now I have been experiencing increasing muscle pain, joint pains in the knees, elbows and fingers, and now have been having stabbing pains in lower back around the kidneys. I would wake up in the middle of the night with shooting pains and stiffness in my left knee and cramps in my calf muscles. The first joint of my middle finger had become extremely soar so that I could not make a fist or grip tightly. I have had a recurring stabbing pain in my chest under the left pectorals muscle. My feet and toes are soar--especially my left foot. When I exercise even the slightest or do some long walking or outside work, my muscles in the arms and legs get very soar and tender, then stiffen up. I had to see a massage therapist to loosen up my legs last week! Six months ago I would be up at the crack of dawn, ready to start my day, but recently I have become very lethargic and tired with little zeal for any physical activity. I have had intermittent pain in my left testicle. We recently moved and I started seeing a different doctor. After a physical exam, he brushes off these symptoms.

Well, I stopped taking the Zocor a week ago, and already my fingers are much better, although my knees and elbows are still soar. The dizziness has gotten worse but I'm hoping that after my body re-adjusts and flushes the simvistatin that that will subside, too. I have drastically changed my diet to drop 15 to 20 pounds and lower the cholesterol with better eating habits and swimming exercise; hopefully that will help alleviate the pain, too.

I took Zocor for 9 months after I had a heart attack. After about 8 months I began having sever muscle spasm in my legs. I had a couple of episodes where when walking I couldn't pick up my feet and thought I was having a stroke and had to sit down and rest before walking on. I had to do this several times to get where I was going. I told my cardiologist and he had me stop the Zocor. The spasms stopped but I never regained the strength in my legs. Today I have had to put ramps in at home cannot climb steps. The ramp is difficult because of the incline but it is better than crawling up my steps to get in the house. I can only walk about 50 steps before my legs give out on me. I cannot walk on uneven ground without holding on to something or someone. I have now had 2 back surgeries because I have been told over and over it is my back with no relief for the legs. This last surgery my left foot drags and my big toe hangs down and I cannot pull it up. Now I fall a lot because of that and have to wear an AFO to keep my foot and toe up so it doesn't drag and trip me. The back doctor thinks it another pinched nerve and wants to open back up again. I am so tired of them trying to convenience me it is my back when I know it was the Zocor and the damage apparently is irreversible but no one wants to agree with me. I am sick of it and just wish they would say yes it was the Zocor and get you a scooter and live the best you can. I know I am headed for that road I use a walker and cane when I don't have someone with me to hold on to. Because I am so unstable on my legs.

Except for having high cholesterol (310), I'm a 29 yr old healthy active female, very petite and weigh 98lbs. My mother has had a quadruple bypass and 4 stents at the age of 54, high cholesterol is just hereditary in my family. My doctor put me on 40 mg of zocor. The first week taking zocor I started feeling strange, a little soar here and there and very tired at times, also I have become very forgetful. It's been almost 2 months now and I have severe pain in my legs. First it was the right leg and now both legs, the pain starts at my lower back all the way down to my cav. I have a burning painful feeling sometimes numbing feeling, its driving me crazy!!!! I can't stand for too long cause I feel tons of pressure on my lower back pushing down my legs, It feels like my sciatic nerve. I went to my doctor and he said he is 95% sure that this is from the zocor medication, he told me to stop it right away. This is my first day without it, I know I need to do something to prevent what happen to my mother, I'm on a strict healthy diet, staying away from all fatty cholesterol filled foods, but there has to be a better way then taking statin drugs! If anyone has some ideas of what kind of alternative meds I can take, please help.

I am 20 year old female and have a bad family history of high cholesterol, iv been taking 40mg/day of lipitor for nearly 2 months.

I was put on Lipitor 10mg 2 weeks ago after my bloodwork from my yearly physical came back that my cholesterol went up again. Levels are HDL 61 LDL 176. After the first week I called my MD to advise that I was having chest pain and muscle pain in my legs and forearm. He said to cut the dose in half which I did last Thursday. Yesterday all of a sudden I had heart flutters the entire day! I am a 43 female who goes to the gym 3 times a week doing 30 minutes of cardio and weights. I eat right and overall I am in great shape except having high cholesterol. My blood pressure is great, had a stress test and echo last year both negative for any problems. I called my doctor today and advise that I was still having fluttering in my chest and that I am stopping the Lipitor. What good is being on a medicine that helps with one problem but then causes others that you may need more medication for???
I have been feeling like crap ever since being put on Lipitor and I believe that it is the medication that is giving me the problems. Last year my MD put me on Zocor and I stopped that after having the muscle pains. I am now hoping that things will get back to normal and I plan on telling my doctor that these "statin' medicines are not for me and there has to be something else.

I have been taking 1,000 mg for about 6 month to lower my LDL to 70 mg from 107 mg. I also take 81 mg aspirin about 30 min. before I take my 1,000 mg Niaspan. My HDL and triglycerides are fine. Lipitor did not lower my LDL and Vitorin caused the tingling in my right arm. After discontinuing Vitorin, I was put on Niaspan. The flushing is OK but the itching on my back was horrible not to mention insomnia. Itching comes and goes but what worries me that recently I have developed the pain in my toes, (excluding the big toe) and when I get out of my bed my feet do not want to support me for at least 5-6 steps. I have been always able to walk for miles! I realized that one of the side effects of Niaspan is elevated concentration of uric acid (gout) or glucose (diabetic condition).
Any similar side effects?

The only thing that I have experienced with Tricor is passing gas. And I don't mean now and then, I am talking about the competitive level for some farting contest.
But does it do what it is supposed to? So far, nope.....But then beside the 145mg Tricor I am also on Zocor 40 mg and even with that combo, I am still over 300 Cholesterol, Triglycerides at 1200+.
This is kind of a last ditch effort as I have been on all of the strong Cholesterol drugs. Doctors have been alarmed at my 535 cholesterol level and the 3265 triglycerides - as for HDL/LDL who knows where thats at.
Now, everyone say WOW! then I tell you I have been like this for over 15 years. From Omega3, to extreme high doses of Niacin (the kind that makes you flushed badly), Lipitor, Crestor, and others with some that I took multiple pills - Nothing touches me. (Now 9 different drugs and nothing)
Sugar levels under 120 avg., BP 120/72 or less. As for Muscles, no problem. My only real complaint is the farts 24/7. Yes, even in my sleep.

I had been on simvastatin a couple months when the debilitating fatigue started. Since I have hypothyroidism I blamed it on that. The fatigue got worse along with severe depression, brain fog. Numbness in my hands and feet and kidney pain kept me up at night. And then the shoulder pain started. It was excruciating. While pulling a dress over my head, my shoulder literally blew up. Turns out my biceps tendon rupture and filled my shoulder joint with chunks of cartilage. After looking at my MRI the orthopedic surgeon said if I didn't have surgery, the excruciating pain would only get worse and I'd lose the use of my arm.
Now, after stopping simvastatin my LDL has gone up to 300. Dr. wants me to start Welchol. After reading the side effects on this site....um...I don't know.

After my heart attack 1 1/2 years ago, my cardiologist prescribed a statin. This dramatically reduced LDL from 125 to 72 within 2 months. But, after no improvement to the HDL, we switched to Crestor + Niacin. At first, I used a non prescription niacin (Slo-Niacin by Upsher Smith). Over the course of 1 year my HDL increased from 40 to 48. We decided that this improvement was too slow, so we substituted Niaspan ER (2000 mg) 6 months ago.
I was very disappointed to see my new lab report this week with the HDL back down to 42. (LDL continues to be no problem and is now 59.) My Doctor reports that I am her only patient who follows her recommendations including daily cardio exercise of 1 hour, good diet, and following medication regimen who demonstrates reduction of HDL with niaspan. We are going to try for 6 more months.
One theory (of mine) is that I have been taking 1000 mg of Niaspan at breakfast and 1000 mg at dinner, and perhaps, I should take all 2000 before bed. I started taking niaspan at meal routine to reduce side effects, and have had very little flushing. But, I will now try to take all 2000 mg at bedtime after a small snack and 1/2 hr after the aspirin. I'll report again after my next lab report, but am curious to know if anyone else has these disappointing results.

Hi, I am a 45 year old male with high cholesterol. prescribed 20mg. of Lipitor to control it. Am having a strange twitching muscle in my right calf since I started the meds. Forearms hurt, trouble sleeping, twitching in my sleep, apparently, tiredness. I'm worried about going off it. My dad died of a heart attack. Would it hurt to try going off it for about 3 months?

I posted several months ago on this string and wanted to update. I had bloodwork done for the 1st time since I quit the 20mg of Lipitor in August. LDL went from 123 to 210. Total Chol went from 191 to 285. HOWEVER all shooting pains I had been experiencing in legs, feet, and chst are GONE! Went back to my Dr. today, told her that same result and my serious objection to taking any kind of statin and she prescribed CRESTOR while telling me it was more potent than Lipitor! WTF!!!

I refuse this course, am drinking 30 - 40 ozs. of water each day now like I should have been, doubled my CoQ10 to 200mg/day, finally getting back into the gym to lose weight and get the HDL up from the level of 36 it is now. also started to drink the new yogurt type "shot" of Promise for cholesterol that provides 2 grams of plant sterols per day.

I will not take statins ever. I WILL find a natural way to keep my Chol under control. I've also been convinced that you don't have to be at or under the 200mlg of total chol to be healthy. Look at your C Reactive Protein and Homosiytes (sp?) If they are in range you should be good.

I know Lipitor was the cause of my rupturing each of my Achiller tendons a year apart while playing tennis in my late 40's Muscle pain soon followed.

60 year old male on zocor for approximately 10 years. taking 80 mg daily.
only recently (within the last 18 months) i noticed some changes going on.
first i had joint pain in my feet, both feet, same areas. the foot pain went away but then the pain traveled up to the back of my legs, behind the knee,
when the muscle or tendons attach. every time i sat for awhile, then got up, the pain was brutal. that lasted about 3 months. later the pain shot up to the joints in my hands. both hands, same place on both hands. when i rotate my thumb or move it, the knuckle area of the thumbs, same place,
hurt bad. i will confront my health care provided at the va on these issues.
she disregarded my previous remarks and said arthritis, hands and feet and perhaps i overextended something at the gym on my behind the knee issue.
i think she is wrong. recently i had a severe cold and did not take the zocor for two days. the thumb pain subsided substantially. i resumed and the pain came back. now it feels as if the pain will travel back down to behind my knees again as i am beginning to feel a pull. any others out there with these issues???

About eight years ago I felt heaviness in my chest along with some pain/discomfort when doing hard physical labor and occasionally in the hot-tub. Following my doctor’s advice and an angiogram, a stint was placed and medication administered – Lipitor and plavix I also went through a 6-month program for cardiac recovery including dietary changes and a proper exercise program. About six month following that I gradually just stopped taking my Lipitor and plavix and returned to my old eating routine and other life-style. I don’t smoke (never did) and don’t drink or otherwise indulge in any recreational drugs. I’ve never been hypertensive with blood pressures typically at 115/68. I maintain a trim and healthy appearing body just naturally or genetically. I eat lots of red meat, not a lot of vegetables, drink gallons of orange juice, and eat much more junk-food than I should. About six years after that (near heart attack) event I was given a “stress test” by my physician… I was then 61 and tested at the level of a 38 year old! Two years after that I had a significant heart attack out in the middle of nowhere! It took almost 6 hours to get me to an emergency room in Spokane, Washington (that’s a story of its own). That was on a Thursday – I was back to work full-time the following Monday (four days later). This time around with more drugs than I could swallow in one gulp! Lipitor, Plavix, Coumadin, aspirin, and carvedilol. The combination or amount was more than I could tolerate and I was weaned off all but the Lipitor and aspirin within a year. My heart has returned to nearly full-function and I have no physician imposed restrictions. All that said, I’ve been gradually developing muscle soreness (pain, actually) in my fore-arms and legs. I’ve been growing more lethargic and tired with each passing month. I’m now 65 and feel that the Lipitor is inhibiting my health… I want to get off it and be “normal” again. Or is it just being sixty five? Can I just quit taking the drug? Leaving only aspirin for blood thinning and the hope of a better diet for cholesterol control.

Went off simvastatin in March, all pain went away within a couple of months, but muscle weakness in legs remained. In October, found out my cholesterol is sky high, over 325. So Dr. wanted to try Crestor 5 mg. Within 1 week, I had overwhelming fatigue, could hardly stay awake during the day and the weakness in my legs was getting worse. So I just went off Crestor. Frustrating!!

PLEASE HELP! My father, age 74, was on lipitor for a year or so and then was switched to zocor a few weeks ago to help control his cholestorol. In the past week, the tightening he experienced in his leg, while on lipitor, has become debilitating leg pain now while he is on Zocor. Ultrasounds have ruled out a blood clot. He has no pain when he sits, but he describes the pain has his calf wanting to explode when he stands and he cannot walk with out the help of a cain. The pain radiates from his leg up to his hip.

His cardiologist has taken him off the zocor for a few weeks to see if there is an improvement. It has been 3 days and he feels a bit of relief. SO here is the million dollar question: His labs indicate his cholestorol is normal now, most likely thanks to the statins.....can anyone suggest another form of meds that will help regulate his cholestorol....say COeq10 and fish oil? Any help is SO appreciated!!! Thanks to each of you for your posts. It is so comforting for my dad to know he isn't developing a new issue and that it can be resolved with the removal of zocor!

I am asking a question on behalf of my brother. He had a stent inserted about 5 years ago due to blockage in one artery. The doctor put him on 20mg Lipitor and Plavix. Ever since then he has been getting Afib. Twice he has had to go to the hospital to get his heart back in rythm and other times he's able to get it back on his own. He has cut back to 10mg Lipitor and takes 100 mg COQ10. Has anyone else had Afib with Lipitor? He seems to think it's the stent causing it and I'm convinced it's the Lipitor. By the way, his cholesterol was not high, only his triglycerides. Thanks for any input.

Just started taking it 2 days ago, already, headache, watery eyes, acid reflux. Couldn't take statins either, Lipitor=terrible foot pain, Zocar= major stomach upset, High Dose Niacin=terrible itching, Crestor=immediate memory lose and now this. Think I need to tell the Dr.'s to leave me alone and let the LDL's role. From reading these post I think there is a group of us that are not supposed to take this crap....

my cholesterol went up 50 points to 245 in
just 1 year. My ldl was always good until
this year. my sister who is also on Effexor XR noticed her cholesterol also increased.
as a result I am being weaned off it.
I also have had sweating problems - my
sister's is worse & I heard on the news
that Effexor XR eliminates REM sleep,
which is why I am always tired. I have been
on Effexor XR for 3 years.

I'm a 38 y/o woman. For 7 yrs I knew my cholesterol has been high. I refused to take cholesterol medication and decided to diet and exercise but that didn't work. I've had 2 children in the past 3 yrs. In May of this year I started having chest pains and palpitations. I had blood tests done. I was given Inderal and also prescribed Zocor 20mg for my cholesterol. It was 243 with and LDL of 178. I took Zocor for a week. I felt so awful. I was weak, I lost my appetite. I was constantly tired. I couldn't even carry my 10 month old son, yet alone care for him. I informed my physician and she changed it to Lipitor 20mg. I thought I was doing fine. I checked my levels again after a month. My cholesterol was 113 and LDL 58. I trusted the doctor knew what she was doing. At the same time I also was taking Omega 3's. I asked my doc to lower the dosage to 10mg. From the time I was taking Zocor and the start of Lipitor. I was feeling tingling and numbness in my arms, hands, fingers, toes, feet and legs. I also was having muscle pain. I asked my doctor about that. She mentioned because of my heart palpitations, it could be symptoms of anxiety and panic. I had feeling of pins and needles throughout my body, not knowing when it would occur. I had muscle pain in my arms and legs and neck pain. I went online to see the side effects of Lipitor and came across this website. I decided to do an experiment. I stopped taking Lipitor 9 days ago. I was on statins for almost 4 months. I don't have the feeling of tingling and numbness, but I still have pins and needles and muscle pain. I have to say, I feel so much better. I hope to get better. I 'd really like to know, how long does the medication stay in your system? What are the effects of getting off it so suddenly. I'd love to feel myself again.

I had 95% occlusion of the major artery in my heart July 2007 with no symptoms except slight shoulder pain on 3 occasions. They did a cath and inserted 2 stents. Started with Lipitor 10 mg. and my LDL dropped from 75 to 112. The MD wanted to double the dose, but I refused because of intermittent nocturnal nausea. MD switched me to another statin and I had immediate muscle involvement and severe nausea at night. She wanted me to try another statin drug and I refused. After a 2 month period of no statins, she put me back on Lipitor 10 mg. daily. I decided to cut the pill in half and take it twice a week, then move to every other day and gradually go to 10 mg. daily. Immediately, the nocturnal nausea started again. Last night I awoke at 2 a.m. with nausea, sweating, sore muscles around my rib cage. Still no sleep at 4:30 a.m., so I got up and tried to eat something. This has been the pattern every night since I went on Lipitor.

I don't know if I can take this any more.

CK

I am a 35 yr old male and have been taking lipitor about 7 yrs. I have a genetically high cholesterol and it has been up to 275. On lipitor its around 175. Over the years I have been on this drug I went from being a normal weight and active to pretty much lethargic and sedentary due to lack of energy and gained ~50 lbs. I couldn't sleep. I got random nausea and fogginess in my brain to the point I could not remember how to perform my job. I usually had minor aches and was bloated. the past year everything has gotten much worse. For a year now, I have been getting large rashes on my body that itch severely and no medications have worked to alleviate them. I found out recently from my doctor that I have a genetic marker in my cholesterol that makes me 3 times as likely to have a heart attack. Its a portion of the cholesterol, i think its called LDL-b or something like that. Anyways, My doctor prescribed zetia to help with my cholesterol since the lipitor wasn't doing it alon. I begin feeling very sick when taking the zetia and after a week or two stopped it. The problems didn't end. As long as I remained on the lipitor, the problems seemed to continue. Its like the zetia released a dam of problems. I stopped the lipitor 4 days ago and have noticed that I feel energy coming back to me and the rash is starting to go away, but I ache severely all over. My shoulders, forearms, and legs are so sore and painful that I can't do anything about this except sleep so I don't feel the pain. I am also very weak feeling and I notice stiffness in my fingers and my grip is very weak compared to how it normally is. I have nausea and stomach cramps and constipation. I feel miserable. I notice its worse in the morning and gets a little better towards the afternoon. I typically took my lipitor in the morning. I do not know if there is a relationship here. Please advise on any help you can provide.

KMJ
07-30-08

I have experienced burning in my arms, legs and feet. If you have how long did it take to stop after stopping Zocor? I have been off for 3 weeks and no relief.

I have been on Lipitor for about 4 years. Now I have an arthritic right knee and the left knee has a little bit of arthritis. My arthritis started getting really bad in both legs my left leg was just as bad as my right leg. Muscle pain was tremendous and getting up and down stairs. furniture, and the car. Then the day before Memorial Day I could hardly move, I thought I was losing both my legs. I could only walk a little bit. No energy. I too had blurred vision with this drug but the doctor said that it probably was just my diabetes. I hurt from the shoulders all the way down to the ankles..It felt like every muscle group was involved. Earlier this year the doctor put my Lipitor up to 40 mg from 20 mg even through my ldl was only 93. My last ldl was 67. The doctors say your cholesterol cannot go to low but I am wondering with all the side affedts I had. I took myself off Lipitor on Memorial Day this year and I feel better. The pain is gone except for the arithritic pain but it is not as bad as what it was on Lipitor. Soo I am done with statins I will lose weight and exercise.