Left ankle symptoms and conditions

About 2 hours after taking my 18th day of generic Wellbutrin XL 150mg. (Sun)the palms of my hands started itching like crazy! No bumps or anything, just intense itching. I immediately applied 1% Hydrocortisone cream to them and after about 10 minutes that pretty much made all the itching go away. I didn't want a replay of that, so I kept applying the HC about every 4 hours all day long, or after washing my hands. That evening everything was okay. Then the next morning, my hands started itching again...so again I applied the HC cream again, and headed off for work...they itched SO bad, and this time it took about half an hour for the HC cream to even begin to work. Then about 20 minutes into the hand itching, the soles of my feet started itching..too wierd! I was driving, so I couldn't apply it to my right foot b/c it was on the gas pedal, but I applied the HC cream to my left foot, ahhhh! Then as soon as I could, I applied it to my right foot. It took about 10 minutes, but it was soon itch free. When it came time to retake my med, I decided not to risk it. I called my prescribing doctor and she was off, and some other doc just said to take Benadryl. Duh, I was at work and #1 didn't have any and #2 it makes me so sleepy, I can't function. Then later on in the day, my wrists got welts on them, then my left elbow got a huge set of welts on it, and itched like crazy...then a few hours later, my left ankle got a huge welt on it and it looked like my ankle was swollen and both my feet and ankles had pin pricking sensations....a few hours after that, my right leg started itching behind my knee...I could feel a welt through my slacks...so again, I went into the ladies room and applied HC cream and it helped. By now I've used 1/2 the new tube of HC cream! When I finally got home, I pulled off my clothes and I had huge welts (hives) all over the back of my right leg. Plus, a big long skinny (horizontal) welt where my bra and wrapped around me. Since I was home, I could take Benadryl...so I took 4 tsp. and jumped into a warm (not hot) bath (they say to use cool water but I couldn't do it) with a cup of baking soda. Felt SOOOO good! By the time I got out they felt much better. I kept taking the Benadryl every 3-4 hours all evening but by the time I went to bed, I had welts on the back of my left leg also and on my buttocks and hips. My head kind of itched here and there in weird places, more like pin pricks but I have really thick hair, so I can't tell if I have any welts there or not. I stayed home from work today to continue on the Benadryl and making sure it doesn't get any worse. It hurts to sit here typing as my panty line is in the middle of a big 3" welt. The Wellbutrin XL seemed to be helping my depression and anger issues, but I assume the MD will put me on something else. I really liked it. It did suppress my appetite during the day but not much at night. Oh well! I'm glad I'm not the only one with these symptoms.

Been on Wellbutrin for almost 6 weeks now. Last week I started having a really itchy scalp, no flakes, just itchy and then bumps would appear where I had itched. My vaginal area was also itchy and I treated myself for a yeast infection unknowingly. This past weekend I broke out in what I now know was hives (urticaria angioedema). First my left ankle swelled (3 inches) and looked like it was sprained, but instead it was super itchy and then became achy and painful. Within 24 hours that ankle went down but the other side swelled up so badly that I had pitting edema in my ankle and could leave dents in it. The third day, still with constant scalp and ear itching, i developed hives and large welts on my inner thighs as well as a large welt on my shoulder. I have been taking benadryl, which seems to help the itching for a little, but not for long enough. Yesterday I was at work and my butt started to itch so badly I had to leave. I had developed huge welts in the creases between my leg and butt right were one sits on a chair! Huge 3-4 inches. I was so uncomfortable. My thumb also had swelled up and I could not move my left hand without burning itch and pain. I finally called the doctor and set up an appointment.
I was told to take benadryl 25-50mg, zantac 150mg twice a day, and Zyrtec once a day to control the hives. This has helped a bit.
When I saw the doctor today and we went over everything, the ONLY change in months has been the addition of the Wellbutrin. I am going to stop taking it today and since my story sounds much like the ones below hopefully this will improve before my eyes or throat swell! Thanks for all your posts.

I'm so glad I found this site. I was prescribed doxy for a rash I got in the Dominican that they thought lead to some sort of infection. The first couple days were fine but one night I took the medication before bed and was up all night with the worst chest pains. I have been nervous ever since that when ever I take the pills I'm going to get the same reaction. I have had chest pains the past couple days and I've been really careful with what I take them with and have been making sure I drink at least two bottles of water with each pill. But today I feel so weak. The last week on the medication I've been so tired I want to take naps when I get home from work which is unusual for me. Today my head feels heavy and my leg feels like it's about to twitch but it doesn't. I've felt some tingling in my left leg and my left arm. I thought this was from whatever infection I had since the rash was on my left ankle, but I think it's from the doxy instead. I've also been feeling a dull pain in my thigh every once in a while. I normally have some anxiety but a couple days after I started the doxy I put myself into a panic and spent the entire day at work researching tropical diseases on the internet because I thought I had one from the rash. I've also had some shortness of breath. I have asthma but it feels nothing like that. Also the doxy made my birth control stop working and I started my period. I thought I just had bad cramps but I'm starting to think they were more stomach aches from the doxy. I've had diarrhea also. And I feel so light headed that I'm going to pass out but I don't. I'm definitely calling my doctor today to get a different antibiotic. Thanks everyone for your posts!

I had Implanon inserted in June 2008, I just had it removed Sept 17 2008. The first side effect was that I gained weight. My appetite increased and I felt like I was constantly hungry. Within the first month I got an Urinary Tract Infection, the infection was so bad that it transferred to my boyfriend through sex.. After a month I started bleeding and it lasted 4 weeks, not spotting just bleeding. I lost my drive for sex, I felt bloated and was too tired ALL THE TIME!!! I was crying over everything, I felt depressed and stressed about everything, my head hurt all the time. My whole body just felt off. I wasn't myself at all. One morning I woke up with a horrible sore throat. I went in for strep test and tested negative. They said it was just a viral infection. A few days after that my muscles started to hurt. My left knee and hip joint began hurting so bad that it was hard to walk and get up out of bed in the morning.(The Implanon was inserted in my LEFT arm). Occasionally I felt tingling in my left arm and fingers. I then notice my left ankle was getting swollen and at that point my whole body felt like it was shutting down.I started to run fevers and thats when I looked up the "possible side effects of Implanon" online. As I read I realized that I had every single side effect even the uncommon more severe ones, but it seemed like my symptoms were multiplied by 100. I called my doctor and she immediately had me come in to have the implanon removed. Today is Sept 22. I have been on bed rest since the implanon was removed. It turns out that my body had rejected the Implanon, treated it like was a foreign object.

I can't believe what I am reading! I have been a competitive runner for over 25 years, and in the past two years I started running mainly trail ultras - races up to 70 miles. This March my husband noticed a huge dent in my left glute muscle that over the course of four races got worse and led to a secondary dent in my hip area. I just assumed I had injured my muscle somehow, but no amount of rest, PT, or stretching has helped.(it's been 6 months now) I developed hip bursitis, medium to severe pain in all my joints, including both knees, my left ankle, and extreme spinal stiffness.

None of the experienced PTs I've been to have seen anything like my dent, and they are baffled by my worsening condition. I'm so scared I'll have to give up running altogether, as my joints are failing me. My PT has advised me to go to my regular doctor to get bloodwork, X-rays, an MRI & all tests done to see if something is wrong with me that is beyond muscle-skeletal. Before all of this, I had low back issues but no joint issues at all.

I found this web site by chance, and suddenly I remembered that several months before noticing the dent, I received 2 steroid injections in my butt, as well as pills & cream for a super severe case of poison oak that covered my whole body and face. Do you think my doctor will tell me if it was Kenalog if I ask?

I, too, am very very interested in any other stories of severe joint pain and inability to run especially after receiving these shots. I hope we can help each other figure this out & get answers.

I STARTED TAKING YAZ IN NOV.07. I AM 49 YRS. OLD AND MY OBGYN GAVE ME 2 SAMPLE PACKS IN HIS OFFICE AND SAID THEY WERE SAFE FOR ME TO TAKE AS LONG AS I NOT A SMOKER(WHICH I AM NOT)THESE PILLS WERE TO HELP ME GO THROUGH THE CHANGE WHICH I WAS STARTING TO GO THROUGH.WELL IN JAN 25 08 I WAS RUSHED TO ER. WITH PAIN SO BAD I COULDN'T WALK IN MY LEFT THIGH. I WAS TOLD I HAD A LARGE BLOOD CLOT AFTER THEY DID A ULTRA SOUND.THEN THEY DID A CATSCAN AND FOUND PARTS OF THE CLOT HAD GONE TO MY LUNGS! THEY KEPT ME IN ICU FOR 6 DAYS GIVING ME HEPRIN AND SHOTS IN MY STOMACH AND STARTING ME ON WARFIN.AND GOT MY BLOOD THINNED TO A 2.5. THEY LET ME GO HOME AND TOLD ME TO FOLLOW UP WITH A DOCTOR IN A WEEK! WELL WHEN I GOT AN APPT. HE SENT ME FOR ANOTHER ULTRASOUND AND FOUND OUT THE CLOT HAD INTENED TO MY GROWING SO HE PUT ME BACK IN THE HOSPITAL FOR 5 MORE DAYS AND MORE SHOTS IN THE STOMACH. AFTER I GOT OUT IN WENT BACK TO HIM FOR A FOLLOW UP AND MY LEG AND FOOT WAS SWOLLEN UP WORSE SO HE CALLED A SURGEON AND HE DID SURGERY TO REMOVE THE CLOT FEB.27 08. WELL A WEEK LATER AFTER THE SURGERY ANOTHER ULTRASOUND SHOWED I HAD CLOTTED BACK UP AGAIN. SO THIS SURGEON SENT ME TO ANOTHER SURGEON IN DALLAS,TEX. AND THEY DID AN EXPERMENTAL SURGERY ON ME THE 19-20-21-22 DAYS OF MAY!!! JUNE THE 27TH HE DID ANOTHER ULTRASOUND TO SEE WHAT I LOOKED LIKE AND I HAD CLOTTED BACK UP TO MY FILTER (WHICH WAS PUT IN MY FIRST SURGERY) SO NOW I HAVE A CLOT FROM MY FILTER(WHICH IS BELOW MY LUNGS) ALL THE WAY TO MY LEFT ANKLE. AND THE DOCTOR SAID HE CANT DO ANY MORE SURGERIES FOR AT LEAST A YR. AND FOR ME TO STAY ON MY WARFIN AND WEAR A COMPRESSION HOSE ON MY LEFT LEG FOR THE REST OF MY LIFE!!! I HAVE TALKED TO 3 LAWYERS AND THEY ALL TURNED DOWN THIS CASE . I GUESS THEY ARE AFRAID OF BAYER. I UNDERSTAND THAT ONE OF THE SIDE EFFECTS IS BLOOD CLOTS . BUT THIS IS NOT NO PLAIN OLD BLOOD CLOT. THIS HAS AFFECTED MY WHOLE LIFE! I HAVEN'T BEEN ABLE TO WORK IN 6 MO.AND I HAVE HOSPITAL BILLS I CANT PAY. THESE PILLS HAS DONE SOMETHING TO MY BLOOD!!!

I took CIPRO for an inflamed gall bladder for two weeks. Two days after I stopped I started to get pain in my left ankle, both elbows, neck and shoulders. I could hardly sleep at night as the pain would not leave. I never knew that CIPRO did this much damage to your body.
J.Nunez
Violet, LA

I took Levaquin for five days, beginning on June 5th. My doctor gave them to me in the individual "blister packs", not in the box or with any pamphlet. I had/have horrible joint pain in my ankles, knees, and hips. The pain in my hands and wrists is almost gone, but the rest is still there and, in some areas, getting worse. I called the doc. and told them about my problem, they said all the side effects should go away after about 72 hours from the last dose. Has not happened, its been over a month and my left ankle and hip are worse. Does anyone have any advice? I'm ******

I am diagnosed with COPD. On March14, 2008, I visited my pulmonologist due to having a bacterial infection in the lungs and nose. I was given a script for Levaguin 750 mg for 7 days. After my first dose, my feet felt like they were on fire. I spoke with the pharmacist and he said it could be a side effect. I finished the meds with a lot of trepidation, feeling uneasy and anxious. However my large toes began to have a tingling sensation, which I reported to my PCP and he said to keep a check on it. I just came from my PCP today, July 8,2008 and now, in addition to my lung problem, I have peripheral neurophathy, involving all my toes and also my hands. This medicine is dangerous, as looking back at the time after I took this medicine, I was seriously considering ending it all! I will never take any medication in the future until I research it thoroughly. I trust my PCP and I trusted my pulmonologist, but I feel the pulmonologist should have informed me of the possible bad sich effects. Be careful out there!!!

Hi! I have started the NuvaRing almost three weeks ago, and I have been feeling sooo tired that I have lost all my interest in everything-except sleep.Also-I have had these weird, charley-horse type cramps in my calfs which swing down and around the arch of my feet. The cramps started exclusively on my right side; but recently I have started feeling them on my left. I would wake up in the morning, get up and I could hardly walk until sometime in the early afternoon. Today, fed up with this crap, I took the damn thing out-and almost immediately the charley horse tightness and pain dropped off. I also knew it would not be long before I would start to gain weight, as I have slacked off my exercise program due to major fatigue. It has been only a day, but I am feeling great,knowing I made the right decision. I have varicose veins in my thigh and calf area-and I fear the blood clots that the ring would predispose me to. I don't need birth control as my husband is infertile; this was prescribed to clear up a cyst.

My 2 yr old was prescribed Singulair yesterday for nasal allergies. He has taken Claritin and Zyrtec in the past with no side effects but they were not very effective on the allergies. I gave him his first dose of the Singulair last night at bedtime just as prescribed. He had a fitfully night, but I thought it might just be that it was keeping him awake. I didn't think about reading the side effects before I gave it to him. This morning he was irritable and did not want to stand up to get out of his crib. I left him with my husband while I went out for a short while and when I returned home found that he was still not standing or walking. We could tell that it was his left leg and then realized it was his left ankle specifically that was bothering him. I then decided to read the side effects in the packet and realized that muscle/joint pain is a serious side effect. His doctor told us to not give him any more and to come in to see them this afternoon. He is very irritable and lethargic some and just not himself - all of this after one pill. I'm just glad we realized it so soon. I will certainly not allow any of my kids to take this drug or any like it.

I took Levaquin 500 mg for 6 days. After about 3 days my left ankle, knee, and the back side of my left thigh became so sore I had difficulty walking. I was extremely tired and slept later than I normally do, which is rare for me. This morning, in bed, my left thigh became so hot it felt like it was wrapped in a heating pad with the temperature turned up extremely high. Later, while getting a shower, I noticed the back of my left thigh had a "hivey" type of red rash on it. I did an internet search and found this page. I'm very concerned because in September 2007 I had a triple heart bypass. I threw the remainder of the Levaquin down the toilet. NEVER AGAIN....

WOW, OKAY I WAS PUT ON LEVAQUIN FOR A RESP. INFECTION. I HAVE ASTHMA THAT IS SET OFF BY ALLERGYS AND INFECTIONS. I COULD NOT BREATH AND WENT TO THE DR. THEY SAID I HAD AN INFECTION GAVE ME 5 DAYS OF LEVAQUIN.. BY THE SECOND DAY I COULD NOT SLEEP, MY BODY WAS HURTING. BUT I JUST PUT IT OFF AS THE INFECTION. COUPLE DAYS LATER MY KNEES STARTED HURTING AGAIN I PUT IT OFF AS JUST DOING TO MUCH AND NOT SLEEPING. I CALLED THE DR TO LET THEM NO I WAS STILL NOT FEELING WELL SO THEY GAVE ME ANOTHER ROUND OF LEVAQUIN. I TOOK THE 6TH DOSE WHILE I WAS AT WORK WITH IN 3 HOURS I COULD NOT EVEN WALK UP THE STAIRS TO THE 2ND FL SOMETHING I DO EVERYDAY. SO I THOUGHT I WOULD LOOK UP THE SIDE EFFECTS I THOUGHT I HAD SAW SOMETHING ABOUT PAIN. THATS WHEN I READ A LOT OF SIDE EFFECTS.. I HAD SWELLING IN MY ANKLES .. MY HANDS, WRITST, ARMS, SHOULDER, LEGS, ANKLE, AND KNEES HURT SO BAD. THERE WAS NOT A MUSCLE IN MY BODY THAT DID NOT HURT. I CALLED THE DR THEY SAID TO STOP TAKEN THE LEVAQUIN, WELL IT HAS BEEN A MONTH. I HAVE SLOWLY FELT BETTER, BUT I HAVE SPENT THE LAST FEW WEEKS FEELING LIKE I HAD SOME KINDA JOINT DECEASE. AND YESTERDAY MY LEGS STARTED HURTING AGAIN AND MY LEFT ANKLE IS SWALLEN. IT SEEMS LIKE EVERY TIME IT RAINS MY LEGS HURT. LIKE I HAVE ARTHRITIS OR SOMETHING. PLEASE IF YOU ARE STILL HAVING PROBLEMS LET ME KNOW...

I have been on Lisinopril for about 30 days, I have developed a pain in my left side that I have not determined the cause. I realized last night that the pain started about the time I started taking this drug. I am taking myself off the drug today to see if the pain subsides, I am calling the Doc this morning. Has anyone else experienced these symptons?

I was given Levaquil after takin Cipro to get rid of a UTI. Shortly after taking a five day prescription of levaquin I started to notice pain in my right foot and knee. My doc told me to take advil and to come back in a week. A week later I still have pain, now it is in both feet, my right knee and my left ankle. It has now been six weeks. I wanted to know how long these side effects are going to last. Any info would be greatly appreciated.

I've been taking Triamtrn/HCTZ Tab 75-50 for HBP, approx 4 years. During that time I have had three occasions when my left ankle became so inflamed, swollen, and painful to touch that I could not walk. On the first two occasions this problem was diagnosis as Tendinitis. On the third occasions I have been told that the problem may be a form of gout that can be brought on by my medication. Is it true that Maxide and its generic will produce uric acid which could ultimately lead to developing gout.

My doctor added Maxide to lower my blood pressure. He said
it could cause some muscle cramps, if it did, just take half the pill.
I have had hair loss. I have numbness and tingling in my hands , legs and feet usually in the morning, when I wake up.
A couple of days ago, I noticed a red rash on my left ankle. It looks like I have been bitten by something, but it doesn't itch.

Started Zocor in May 2005, took for approx. three weeks. Had been given samples by GP. Stopped June 10, 2005 due to problems. Following is a list of symptoms as they occurred. Head shake, thinking and speaking problems, difficulty swallowing, weakness, low back pain, muscle spasms, pain in legs (especially left leg) Kidney pain, dark urine for one day only, and especially extreme fatigue. GP said was Myopathy. didnt seem to know cause. Continued to get worse untill approx. July 15, 2005. Started phy therapy. This helped to build back the muscles lost but would only build to a certain point. Presently, april 2006, Most of the symptoms have abated but I still have difficulty walking and standing very long. Had to quit working, could not handle. I will keep updating as I progress. This has been some nightmare.

Irregular heart beat.
Pain in left side of chest, back, neck, shoulder and left arm.
Swollen, painfull left ankle.
General aches.
Only 3 hours sleep a night.

I had a stubborn sinus infection and received a prescription for Levaquin after two other antibiotics failed. In my doctor's defense, she used it as a 3rd line defense.

Still, after taking 7 days of a a 10-day, 500 mg course, I woke up with severe pain in my left ankle, as if I had turned it and sprained it playing basketball or soccer or something. The topside of my foot just under the ankle was swollen. I could hardly walk from the pain. I also had a duller, non-specific pain in my lower back. I had not been particularly active for about a week, so I could not imagine what was wrong.

Because of the lingering sinus infection, I decided to see the doctor, who identified the possibility that Levaquin might have caused the pain. He recommended I stop taking the Levaquin and treat the ankle like a sprain. He also said that if the pain continued for more than a few days, I should get an MRI to investigate the possibility of tendon or ligament damage.

This is the most bizarre medical thing that has ever happened to me. I usually investigate the drugs I am prescribed, but I could not have imagined the prevalence of side effects to Levaquin. The main web sites just include "joint pain" as a possible side effect, but that doesn't come close to describing what has happened to me. I just hope the symptoms do not linger as they have for so many others.

WED, 29 JUL BY BETTY
63 YRS OLD - HAVE BEEN ON MED SINCE THE 60'S. FIRST WAS EUTHROID THEN SYNTHROID BOTH WORKED VERY WELL. SINCE MAR '05 DR CHANGED ME OVER TO LEVOTHYROXINE (BAD IDEA). HAVE THE FOLLOWING SYMPTOMS: FATIGUE, TINGLING IN THE LEGS, NUMBNESS IN HANDS BUT THE MOST UNBEARABLE WAS THE CRAMPS IN MY LEFT ANKLE & CALF. THOUGHT I HAD A PINCHED NERVE. WENT TO A CHIROPRACTOR WITH NO PAIN RELIEF, THEN A ACUPUNCTURIST (SOME RELIEF) THEN IT HIT ME...SIDE EFFECTS FROM THIS DRUG. QUIT TAKING IT & WILL SEE MY DR TOMORROW AFTERNOON AND INSIST ON GOING BACK TO SYNTHROID. I HAVE A HARD TIME COPING WITH THIS PAIN AND WILL NOT LIVE THIS WAY. EVERY STEP I TOOK WAS EXCRUCIATING ESP WHEN I HAD TO WALK FR THE PARKING LOT TO MY JOB. I EVEN HAD TO SIT IN THE BATHTUB TO TAKE A BATH MY LEG HURT SO MUCH. I THREW AWAY THE POISON (PILLS) THAT CAUSED ME SO MUCH PAIN.
THE CRAMPING COMES AND THEN SUBSIDES BUT NOT FOR LONG. TRIED USING THE HEATING PAD, MASSAGES BUT IT KEPT RETURNING. HOPE THIS HELPS ALL THAT READS THIS.
WOULD LIKE TO HEAR MORE FEEDBACK ON OTHERS EXPERIENCES. THOSE THAT HAD THE LEG CRAMPS CAN YOU RELATE HOW IT AFFECTED YOU AND TO WHAT EXTENT.
THANKS TO ALL OF YOU FOR SHARING YOUR STORIES , WHICH CONFIRMED MY SUSPICION ABOUT THIS HORRIBLE DRUG.

Started on Vytorin (Zocor 20 mg/Zetia 10mg) on 12-23-04. I had previously been on 40 mg of Pravochol with 10 mg of Zetia with little side effects. However after 6 months on Vytorin my sex drive has diminished and my left ankle swells and aches after my daily 30 minute jog (have been jogging for over 25 year without any ankle problems). 3 days ago I began splitting my Vytorin 10/20 pill and have noticed the ankle pain has subsided greatly. The ankle pain has persisted for the last 6 months while on the Vytorin. My cholesterol has plummeted to 133 (which I personally think is too low). I am planning to have my doctor put me back on a lower dose (20mg) of Pravachol and Zetia as before. Anyone esle have this problem with Vytorin?

My left ankle has swelled and the pain in the arch of my foot is sometimes very acute. I began taking Lipitor a little over a week ago and my ankle starting swelling about 3 days ago. I am a 53 year old woman. The swelling will not go down unless I keep the foot elevated for a long period of time, but it is constantly sore.

I have been taking Advair since July 9 2004; almost immediately I begin to have heart palpations and anxiety attacks at night. My left side is numb from head to toe. I have headaches all the time. My left arm has tighteness as if I am having a heart attack and my left leg feels as if the blood is pooling in the calf and ankle. My left ankle swells up often and when I attempt to walk for exercise, my right leg literally gets so tight I have to stop and rub it to relieve the pain. My lower back hurts and while attempting to find the problems I had a spinal tap which has created a permanent pain in my back. I have chest pains and the constant fear of having a heart attack. My quality of life went from the best to the possible worst. I have had C-span, MRi, Cartoid Artery test, chest xrays, Spinal Tap and every test came back with good readings. I have been checked for Lupus, MS and my Thyroid and every other test there is. One doctor even told me "maybe you need an exorcist" because all the test where good. I has been horrible and I am beginning to get the fatigue that I have read about on the website. In the middle of exercising I just want to lay down on the floor and go to sleep. I have gain 25 pounds since September. How crazy is that. Before I was diagnoised with Asthma I worked out 4 time a day, even after being treated for Asthma I was able to work out when I was only using the OVAR/Singular. Once I started the Advair everything change. When I use the disk I have an immediate reaction. At first I kept questioning myself and wonder if it was something else. I informed my doctor on 2/11/2005 that I had a problem with the Advair, he instructed me to use it once a day and continue with my emergencies inhaler when needed. I am schedule for a major test tomorrow on the nervous system, after reading these testomonials this morning, I called the office and told them I was taking myself off of the Advair and that someone needed to advice me from that point. I have never felt worst in my life, but I think I am about to feel better.

Left ankle and knee ache and are very swollen. Other joints hurt as well. Left leg has pitting edema. Upper back pain. All since starting Toprol. Spent 5 hours in ER to rule out DVT only to be told. "You must have done too much exercise". I've been exercising for 35 years and never had this problem.