Lesion symptoms and conditions

Im 29 Years of age, male, the doctor gave me AVELOX 400 for chronic sinusitis 2 days of taking it it was ok. the third day is a nightmare. Begin to have bad dreams, confusion, my blood pressure started to rise up and different parts of my skin begin to swell and started to itch. the worse part is my penis started to itch and then afterwards began to swell and lesion on in. so freaking scary. Please don't take this drug. and for those who made this drug. BAYER right? Please recall Avelox. Medicines are supposed to cure people, not worsen the problem. not only BAYER but all other companies who sells drug which have serious side effect to recall your medicines. If i were only a billionaire i will buy all your medicines and burn it all. O well humans sort of Guinea Pigs. Thats the reality.

After taking remicade for appx. a year, I started having heart problems, A fib, ending up having heart surgery, a kidney has collapsed, and had a lesion appear which was squamous cell carcinoma. All these problems developed have taking remicade; I do blame it for my problems. My Dr. treated me for ankylosing spondylitis, a form of RA. After so many problems, another Dr. told me that I did NOT have AS. And it did not help my pain at all. This is a troubling experience for me, and has been the worst thing that ever happened to me.

i got my mirena IUD in last year, Ive been getting a lot of the side affects like headache,mood swings,depression,weight gain,hair lost,nausea,really bad sharp pains,insomnia,and really heavy periods and, i couldn't feel the string...so yesterday i went to the hospital with the sharp pain and they did a CT on me.....get this, they told me that the IUD is in the pelvis,however, it is outside of the uterus and adjacent to the sigmoid colon and, a low density lesion in the adnexal region probably representing an ovarian cyst which has ruptured!!!! so they sent me home with some pain killers and told me to call the doctor that put it in......ohh yeah and I forgot to tell you they said i need to have surgery to remove it.(how nice!!!) GOOD LUCK TO EVERYBODY

After reading these posts I am more confused than before, because my experience is so far very different. I was diagnosed with DVT about two weeks ago and now take Coumadin daily; the Lovenox injections have been discontinued. The reason I'm so confused is I now feel the best I have in 5 (five) years.

Before being placed on the anti-coagulants I had memory and concentration issues that were progressively getting worse and greatly affecting my job, and had daily headaches. I had joint pain that made it difficult to get up after sitting for awhile; they felt constantly inflamed. I felt fatigued all the time and my muscles hurt like I had really pushed them; I just didn't have any strength, and had muscle cramps. I was constantly yawning and found my jaws hurt from clinching my teeth, subconsciously trying not to yawn. I was extremely sensitive to physical touch, even hugs hurt. I also felt extremely depressed and cried almost daily. My lips and left cheek tingled, as well as other parts of my body. Plus I would get the feeling of sudden pressure in my head (different from a headache) like it was going to pop off, and I my eyes didn't seem to track what I looking at and had difficulty in remembering or comprehending what I just read.

About 6 (six) days after starting treatment it completely changed and these symptoms are essentially gone. I have talked with my doctor and pharmacist and they are baffled. I am concerned this change, while welcomed, may indicate an underlying condition that is not yet diagnosed. Has anyone ever heard of such an impact from starting Coumadin treatment?

Is there anyone who has taken lisinopril and had a mri of the brain that has showed white lesion on your brain that are unexplained? Also how long do you think it takes to get this drug totally out of your system?

I was taking doxycycline for a lesion on my face. I started to have tingling of my feet and fingers but did not associate it with the medication. I only used the doxycycline for two weeks. The tingling in my feet lasted for almost 5 weeks.

Several months later I went on Doxycycline because I thought I had lyme disease. After being on the Doxy for one week I started up with burning sensations of my hands and feet. Puffy, red hands...burning on different parts of my body. My Md said it was anxiety! An immunologist said it was peripheral nueropothy from drinking too much!!! I knew both diagnosis were bogis....then I started to research doxy and came upon this site...thank God. I finished the month of the Doxy. I have been off the med now for two months and the symptoms are finally starting to subside.
I can remember waking up one night and my entire chest felt like it was on fire. Wearing shoes was so painful that I wore slippers to work...I was a burning tingling mess and I am convinced it was the doxycyline.

I was on nuvaring for about 1.5 years until I quit late summer/early fall of 2008. I'm 25 and I quit because I always felt "dry" and had no sex drive. I felt like I was just pumped full of hormones and wanted to give my body a break and quit all birth control for a while. Around the time I quit, I began to bleed during sex. Not every time, just "hit and miss", not very much, but one time there was quite a bit. I ignored this for a while and then started looking things up on the net which lead me to freak and think I had cervical cancer. I rushed in for a pap test and even during the exam, I bled (pretty badly) this made my results inconclusive and I have to go back in 3 months after the cells on my cervix have re-grown and they can get a proper sample. I'm less worried after finding this forum, but wondering how many others out there have suffered from the mysterious bleeding during sex? Is anyone still suffering from this after discontinuing use?

Other side affects were weight gain, panic attacks, and major hair loss.

I had been taking bactrim for a week when one morning i woke up feeling achy, tired, and light-headed. I noticed a slight rash forming on my arms but didn't think much of it bc i had been on the Bactrim for a week already. Then the symptoms got wayyyyy worse. I started to form lesion like sores on my vagina, and I immediately saw a doctor to get tested for STD's. The gyno examined the area, and she said it did not look like herpes but that she would test for it just in case. She put me on augmentin bc she said I definitely had some sort of infection down there. After taking 4 doses of augmentin almost all the lesions went away. The STD tests (blood, culture, and urine) all came up negative, as I expected they would. Has anyone else had genital reactions to bactrim???? Because as of right now the doctors are unsure what caused this outbreak/infection.

This is my second round with Doxycycline for a Staph infection (probably MRSA - the culture isn't back yet); the first round was unpleasant, especially in terms of feelings of heat in my head, wooziness, and rather severe stomach upset and esophagitis due to reflux. I am a Chinese herbalist, and tried going that route with the first bout of the infection (which fortunately is at the skin level), but didn't get much relief so went the route of the 'big guns.' The infection cleared up, more or less, but three weeks later I began to get another new lesion. Grr. Back to Doxy. This second time I've been more proactive, however: Ginger is used in a lot of chinese formulas to help with digestive upset, so I've been taking a couple of pieces of candied ginger as soon as the stomach upset gets going, and hey it works! By the way, I am taking capsules, and I find that lying down on my LEFT side actually helps prevent the reflux pain - the exit of the stomach is on the left side, and since capsules float, lying on my left side keeps the med closer to the exit than the entrance... or so it seems. Whew - I'm glad this stuff is out there, but I'd really like to be done with it - forever....

Drug Saf. 2007;30(6):515-25. LinkOut
Statins, neuromuscular degenerative disease and an amyotrophic lateral
sclerosis-like syndrome: an analysis of individual case safety reports
from vigibase.Edwards IR, Star K, Kiuru A.
The WHO Foundation Collaborating Centre for International Drug
Monitoring, the Uppsala Monitoring Centre (UMC), Uppsala, Sweden.

BACKGROUND: The WHO Foundation Collaborating Centre for International
Drug Monitoring (Uppsala Monitoring Centre ) has received many
individual case safety reports (ICSRs) associating HMG-CoA reductase
inhibitor drug (statin) use with the occurrence of muscle damage,
including rhabdomyolysis, and also peripheral neuropathy. A new signal
has now appeared of disproportionally high reporting of upper motor
neurone lesions.

AIM AND SCOPE: The aim of this paper is to present the upper motor
neurone lesion cases, with other evidence, as a signal of a
relationship between statins and an amyotrophic lateral sclerosis
(ALS)-like syndrome. The paper also presents some arguments for
considering that a spectrum of severe neuromuscular damage may be
associated with statin use, albeit rarely. The paper does not do more
than raise the signal for further work and analysis of what must be
regarded as a potentially very serious and perhaps avoidable or
reversible adverse reaction, though it also suggests action to be
taken if an ALS-like syndrome should occur in a patient using
statins.

METHODS: The 43 reports accounting for the disproportional reports in
Vigibase (the database of the WHO Programme for International Drug
Monitoring) are summarised and analysed for the diagnosis of an ALS-
like syndrome. The issues of data quality and potential reporting bias
are considered. RESULTS: 'Upper motor neurone lesion' is a rare
adverse event reported in relationship to drugs in Vigibase (a
database containing nearly 4 million ICSRs). Of the total of 172 ICSRs
on this reported term, 43 were related to statins, of which 40 were
considered further: all but one case was reported as ALS. In 34/40
reports a statin was the sole reported suspected drug. The diagnostic
criteria were variable, and seven of the statin cases also had
features of peripheral neuropathy. Of a total of 5534 ICSRs of
peripheral neuropathy related to any drug in Vigibase, 547 were on
statins. The disproportional reporting of statins and upper motor
neurone lesion persisted after age stratification, and such
disproportionality was not seen for statins and Parkinson's disease,
Alzheimer's disease, extrapyramidal disorders, or multiple sclerosis-
like syndromes. DISCUSSION: Because the cases were sometimes atypical
we propose the use of the term 'ALS-like syndrome' and speculate
whether this is part of a spectrum of rare neuromuscular damage. The
diagnosis of ALS is often problematic, and the insidiousness and
chronicity of the disease make causality with a drug difficult to
assess.

The disproportionally high reporting makes this an important signal
nevertheless, since ALS is serious clinically and statins are so
widely used. Wide use of the statins also makes a chance finding more
probable, but is unlikely to cause disproportional reporting when
there are no obvious biases identified.

CONCLUSION: We emphasise the rarity of this possible association, and
also the need for further study to establish whether a causal
relationship exists. We do advocate that trial discontinuation of a
statin should be considered in patients with serious neuromuscular
disease such as the ALS-like syndrome, given the poor prognosis and a
possibility that progression of the disease may be halted or even
reversed.

PMID: 17536877 [PubMed - in process

My 8 yearold daughter after about 2 months of being on singulair started having muscle spasms on her right side of neck and face. Later the spasms started getting worse. She said like she felt someone was jerking her head. She also started having uncontrollable kicking spasms. We had an MRI of her brain and spine done. Nothing, she was fine. We had a biospy of a small lesion from a prior cut; nothing again. Finally, we took her off the singulair, the only drug she was taking. She is now fine. Her primary care physician, said mmmmm, possibility. It just seems too coincidental that the spasms started after she began taking singulair then stopped after we took her off. Anyone else, have similar experience??

I started lisinopril 5mg 7 months ago. Before that I tried Hctz to control my BP. At about the same time I thought I was having trouble with my tonsils (it was a tickle in the throat). I did have a lesion of some sort on a tonsil, the ENT didnt think it was a problem, but I continued to have this choking feeling and cough. So we tried antibiotics which did nothing. After so long I opted to have my tonsils out in Sep '04. No one brought up to me there are side effects on lisinipril like a cough, except a new Pharmacist that I work with. So here I am, hoping to get off this stuff, by doing some exercising, and cutting out salt.....The tonsilectomy was horrible.....(Im 39) and I sure home this feeling in my throat stops!! OH....I also have a lost of taste!! I want to swallow again without this feeling!!! Pray for me.
Connie