Light weights symptoms and conditions

I was diagnosed with SLE (lupus) when I was 14, I'm 21 now, and I've had to be on prednisone all this while. The dosages alternate between 60mg (the highest) and 2.5mg (the lowest), I just went for a routine check up today and found out that my protein level in my urine is at an all time high. So the doctor is pushing me back up to 30mg of prednisone. Its 2 am, and I am sitting in bed crying because I don't want to have to go through everything again; the weight gain, the moon-face, everything. I know I may sound shallow, because ultimately, the medicine is keeping me alive, but the side effects are terrible. Very few people understand that its not fat that you're gaining, and the remarks that I know I am going to get are enough to drive me insane.Is there anyway the water retention or the weight gain can be stopped or decreased?

My Dad is 75 years old has been in and out of the hospital because of exasperations brought on by COPD. He is fine when he gets out of the hospital with 40mg of Prednisone then like many others tapers to 30mg, 20mg then 10mg until he isn't taking any. Then the exasperations start he's back in the hospital and the Prednisone cycle begins again. I have notice he has mood swings as he has become very irritable. He also use to work out with light weights ever morning, he no longer has the desire. He also use to go for walks, in the park treadmill etc. he no longer does those activities either. I also notice his eyes look different. I realize this drug is keeping him alive, but he has become a different person.

An element of the side effects of Singulair that are listed here are musculo-skeletal symptoms. Quinolones such as levaquin are known to cause those issues. Singulair is a quinoline, while not the exact same category, their roots are similar. It makes the possibility that the symptoms have a common cause worth pursuing.

Here is an example of some poor rats in Tokyo that were selected to prove that the symptoms in humans were real. Maybe we should tell the levaquin board that at least some of their problems have been known since 1997.

1: Toxicol Pathol. 1997 Nov-Dec;25(6):635-43.Links
Toxic effects of quinolone antibacterial agents on the musculoskeletal system in juvenile rats.Kashida Y, Kato M.
Drug Safety Research Laboratory, Daiichi Pharmaceutical Co., Ltd., Tokyo, Japan. JDN07402@niftyserve.or.jp

Quinolone antibacterial agents have adverse effects on the musculoskeletal system in humans, consisting mainly of myalgia and arthralgia, and additionally of tendon disorders and rhabdomyolysis. The present study was conducted to examine the toxic effects of quinolones on the musculoskeletal system in juvenile rats using light microscopy, 5-bromo-2'-deoxyuridine (BrdU) immunohistochemistry and electron microscopy. Single oral administration of 900 mg/kg pefloxacin (PFLX) or levofloxacin (LVFX) was found to induce lesions in the muscle + fascia, tendon + sheath, and synovial membrane, in addition to articular cartilage in the fore- and hindlimbs. Articular cartilage lesions were not necessarily associated with changes in the muscle, tendon, and synovial membrane, or the reverse. Among all lesions, the ankle and elbow showed the highest incidence and severity. Changes were more severe in the PFLX than in the LVFX group. Lesions in the muscle + fascia, tendon + sheath, and synovial membrane were similar and characterized by edema and increased number of mononuclear cells, many of which were positively stained with BrdU, as well as vascular endothelial cells in the Achilles tendon sheath and synovial membrane in the ankle. Electron microscopic examination revealed an increased number of fibroblasts and macrophages and collagen deposition in the matrix of the synovial membrane and tendon sheath. Capillary endothelial cells were hypertrophied, increased in number, and stratified. These results suggest that quinolones have toxic potentials in the muscle, tendon, and synovial membrane in addition to articular cartilage, and that local vascular hyperpermeability may contribute to the development of these lesions.

PMID: 9437810

I have just come across this site, while looking to find out why I have been experiencing heart palpitations for the past two months - out of the blue!!! and usually "exercise" induced. I had some tests and have been told they are Premature Atrial Contractions "PACs". I started taking Yasmin in April, after having tried others over the past year (tri-cyclen lo and alesse) which did not work for me as the progestin was not strong enough. I am in my 40s and never took the pill before. Yasmin was great, it significantly reduced my "physical" pms (severe inflamation, severe bloating, severe sore breasts) which I experience for 2-3 weeks a month. However, sometime in mid to late June, I started getting palpitations/tremors out of the blue. The first episode freaked me out and lasted for about two weeks. At first I thought it was allergy medication mixed with my thyroid med, which can happen - but I cut out the allergy meds and still got them. They seem to come about 6hrs to a day after I fexercise/figure skate and they last from 2 to 5 five days. It's very irritating and nerve wracking, and I feel very agitated. I am also out of breath more than usual when walking up stairs, a little light headed and have some tightness in the chest. My legs also are weak, which makes no sense given my exercise regimen. I then lowered my thyroid replacement from .125 synthroid to .100 - too much thyroid med can cause some palpitations. Anyone who has mistakenly taken a second thyroid pill having forgotten that they already took one will understand. Even with the lower dose I am still getting the palpilations. I am totally at a loss as to why all of a sudden this is happening to me (perhaps perimenopause??). I have had the odd flutter here and there in my live, but nothing like this. It just doesn't make any sense ag ll. Can one's health just change like this overnight?. I am otherwise healthy, slim, have "lower" blood pressure (apprx 100-90/70-60)I skate 3 to 5 times a week, I have a full time job and yes I do push myself, but this is getting ridiculous. The only thing I can attribute it to is the Yasmin, ... but my symptoms only started after a few months not instantly, whereas it would seem that most of the the women here noticed the side effects faster. I hate to stop the Yasmin because I will have to return to pms "hell", but I suppose I will give it a try to see if the palpitations subside. At this point, I have been offered a low dose "beta blocker" and have refused. I am stunned to think that all of a sudden I have heart issues, especially since my Dr has always kidded me my that I will never have heart problems with my blood pressure. I will stop the Yasmin tonight and post another message in a few weeks one it is out my system. Here's hoping it is the Yasmin.
KarenSkaterGirl