Lupron symptoms and conditions

I have had two shots of Lupron, as a result I've gained almost 30lbs, had very bad joint pains and little hot flashes. I also experienced hair loss and became moody at times. However, my doctor did warn me that I would gain weight as a result of the shot and that I may experience hot flashes. December 2009 will make one year since my first shot the second shot was in April and I"m just beginning to feel normal again. It is now November 2009

I started Lupron injections 9/28/09 and I started having side effects almost right away. Headaches, mood swings, socialized anxiety, lack of appetite, no short term memory, no short term memory (LOL), confusion and extreme inability to focus, hot flashes/night sweats, tired all the time. Also, when I'm not having a hot flash/night sweats, I am chilled to the bone. This may be due to my appetite, which in turn is odd that I have cravings of chocolate. My husband has to pretty much force me to eat a meal. The chocolate craving goes beyond anything else, it's strange for me to eat like this. From what I understand is that it could be a hormonal issue due to the Lupron. Also chocolate can trigger endorphins that can help with pain, seeing how as the Lupron is doing nothing in that department!

ok, so I am 28yrs old just had my lap for endo on October 1 and my doctor has recommended lupron, and am going to be getting the med in a week to 2weeks,but after reading this I am soooooooooo scared to even get near this med. Its like you either take this with the hope of saving fertility and no pain..or not and have endo ravage your body and you will live with unbearable pain!!! I have no idea what to do,and i am so scared after reading this. Is there anyone that did not have weight gain, headaches etc...anyone that can testify that lupron actually worked for them? did any one have a baby after doing this. my bigs thing is being able to have a baby. Cause right now its my health on the line, my ability to have children, my ability to have a normal life free of endo pain or these crazy, horrible side effects...please help me!!!

ok, so I am 28yrs old just had my lap for endo on October 1 and my doctor has recommended lupron, and am going to be getting the med in a week to 2weeks,but after reading this I am soooooooooo scared to even get near this med. Its like you either take this with the hope of saving fertility and no pain..or not and have endo ravage your body and you will live with unbearable pain!!! I have no idea what to do,and i am so scared after reading this. Is there anyone that did not have weight gain, headaches etc...anyone that can testify that lupron actually worked for them? did any one have a baby after doing this. my bigs thing is being able to have a baby. Cause right now its my health on the line, my ability to have children, my ability to have a normal life free of endo pain or these crazy, horrible side effects...please help me!!!

I am 19 yrs old. I started NuvaRing about 12 days ago. I was hesitant to start with but my OB/GYN said it was the last thing to try to suppress my endometriosis. He assured me that the side effects were minimal and I'd feel like I did on the pill without having to pop a pill every day. After being on Depo Lupron for 6 months that sounded pretty good.
The first couple of days were fine, I just was a little tired but I thought that was from the surgery I had a week before. Then on the 5th or 6th day I started getting down for what seemed like no reason. Then I got this debilitating sharp pain in my lower left side. Not to mention heavy pressure. By the 7th day my depression was worse than it had been in about 6 months. My boyfriend told me that I seemed very much on edge and down. That upset me and I seem to be getting worse instead of better.. I started crying when a friend just said hi. I've only been on it for about two weeks now and I really don't think I can continue to be on NR.

I have endo and have had surgery for it and now I have not had any pain with my lupron shot but I have become VERY depressed. My husband doesn't understand! Thank God I only have to take one more shot (that lasts for 3 months) and then I should be able to have kids... if I still have a husband by then. My doc put me on an estrogen tablet to help with the hot flashes and that has helped. I feel hot but don't sweat. I am also on lexapro which helps with the depression but heaven forbid I miss one!

I took lupron for about a year or so back in 1999. I don't remember a lot, just the hot flashes, etc, that I was warned about. I began to have memory problems a little. As the years passed by, it became worse. It is 10 years later and I have no short term memory. I have searched and searched to figure out what is wrong with me. My memory is gone. Its a sad thing, that this shot is still being given.

I had a lap done last year in May and my doctor removed an adhesion that was hanging above my uterus. Also a fibroid (3 cm) was found in the muscle and is located right against my bladder. My doctor could not remove the fibroid because of its location and because of a risk that I might have scar tissue and could be a problem to get pregnant. He also said that I could have some other complications, like lose a lot of blood. I feel like he is not being straight with me. I also have ovarian cysts which is common in the women in my family. Since a teenager, I always had really bad cramps and heavy bleeding. As I got older, it became worse. Before I had the lap done, I bleed for 6 weeks straight. I was changing pads every 30 minutes. Then my stomach extended so far out that I looked pregnant. I could not sit or stand. My husband had to take me to the E.R. An ultrasound was done and found that my uterus was enlarged (9 cm). I was put on Nothridone to control the bleeding and to treat endometriosis. After taking 2 months of this drug my doctor did a vag lap and abdomen lap. Everything was good that is what he said. I believed it. I was doing better. I was working and had no pain for 8 months. Then it all changed for the worse. I started to have really heavy menstrual bleeding and lots of blood clots. I felt week all the time and sick. The bleeding went on for 8 weeks and finally my doctor said that I had to take Lupron injections. I asked my doctor if he could just do a myomectmy and he said no because that was should be the last result. I could no longer stand the pain and I asked him what kind of side effects come with this drug. He made it sound like it was not bad and that there are very little side effects. He gave me a some information about the drug and I read the information and I did a lot of research. I was terrified but I had to make a choice. I was calling in sick because I could not work with the pain and worrying about embarrassing moments when my pads failed to keep me from overflowing. So I took the 1st shot in May along with add-bak therapy which is Nothridone. The bleeding tapered off slowly and the pelvic pain decreased. I did not feel any side affects right away until the second week. I started to forget things and would just stand in the middle of a room feeling confused. I always had headaches since a child but now they are pounding headaches, which I cannot stand any noise. I also can't stand the light. I have body aches like I have the flu and have problems with my right hip all of a sudden. I had a x-ray done because my doctor thought I might have fractured my hip. There was no sign of a fracture but my pelvis id tilted. I have some arthritis in my spine which I do not understand how that happened. Sometimes I cannot walk and I have to use crutches to get around. I cry all the time because I am extremely sensitive and confused. I use to be a very strong person and now I just cry all the time. I called my doctor to tell him what I have been experiencing and he said its all normal. I have already had a total of three Lupron injections and the symptoms just get worse. I have been spotting here and there, sometimes I have a pinkish discharge, and now the pelvic pain is back. My doctor knows this and he just says its normal. I requested for another ultrasound because I am worried something is wrong and he said that I have to wait until I get the 6th injection.I feel like my doctor is insensitive but he is supposed to be the best GYN doctor where I live. I also want to say that I have gained 20 pounds in three months. My sex drive is gone. My hair is thinning. I lost my job because I ran out of FMLA. This has been a nightmare! I am losing trust in my doctor. My poor husband and family are having to put up with what I am going through. I pray all the time to help be stay focused and think positive. I just do not know what to do anymore. Is there anyone out there that can give me some advice?

Hi. I just had a laproscopy done 3 weeks ago for endometriosis. I am 26 yrs old and have been dealing with this pain for almost 2 yrs now and it is the worst pain in my entire life. My doctor is now suggesting Lupron because even after the laproscopy the endometriosis was level 4 and had bonded to my intestines and literally trapped my ovaries and uterus against the lining of my stomach. The pain was a 15 to say the least and the past 3 mos it had landed me in the E.R. Finally the docs figured it out. I started my period 2 weeks after the surgery and the pain was still pretty bad. An 8. Now I am seriously considering Lupron. My health is on the line and this pain is not right. At this point I am considering a hysterectomy if Lupron does not work. Any help suggestions please? Monday I follow up with the Dr.

lupron makes me a bad person. i easily get irritated even on very little things. mood swings is very out of this world. i'm on my day 4 of lupron and i can't control my emotion anymore. i do deep breaths to try to control it but it doesn't work for me. i really have to shout my emotion or else i feel i will burst or die of heart attack. i don't know what to do anymore. i have to be relaxed to have a successful ivf. need your advice.

I was injected with Lupron and the shot last for three months. I had the shot in order to stop my periods to increase my blood count for surgery to remove fibroids. The first two weeks, I spent having a very light cycle. I'm 2 1/2 months in and haven't had one since. I have, however, had menstrual cycles and never had them when I had my cycles before Lupron. I have a high tolerance for pain, but I was constantly popping Motrin to deal with the cramps. I experience pressure in my head during the second month, but it has gone away. My sex drive sky rocketed since I've been on the shot, but I have some vaginal dryness. My energy has also decreased since being on the shot and I don't work out like I use to. The three months is almost up so hopefully I can get back to normal once it's over.

im currently on my fourth month of treatment with lupron and would like to know if anyone that had fertility problems was able to conceive after a course of lupron...? im 32 and have 2 beautiful children, but would like one more before i undergo a hysterectomy...i have been diagnosed with endometriosis, adenomyosis and severe pelvic adhesion's. i was in so much pain that it was ruining my life...the lupron has been pretty great this time around...six years ago i did it without any add-back therapy, but this time im taking progesterone along with it and the side affects have been minimal...still have mood swings and a decreased sex drive, but no hot flashes or night sweats. its definitely worth the pain relief...for me anyways.

ok, so I am 28yrs old just had my second lap for endo and my doctor has recommended lupron, after reading this I am soooooooooo scared to even get near this med. Its like you either take this with the hope of saving fertility and no pain..or not and have endo ravage your body and you will live with unbearable pain!!! I have no idea what to do, my post-op surgery appt is this week, and i am so scared after reading this. Is there anyone that did not have weight gain, headaches etc...anyone that can testify that lupron actually worked for them? Cause right now its my health on the line, my ability to have children, my ability to have a normal life free of endo pain or these crazy, horrible side effects...please help me!!!

My doctor warned me that the pain from endometriosis would get worse before it gets better... it definitely got worse, but I'm not seeing the "better". My pain is less frequent, yes, but it's still there, and sometimes worse than it used to be. I did 2 injections, and since I'm not satisfied with the results, I won't be continuing this therapy. The mood swings that I went through almost cost me my marriage - there's only so many times crazy behavior can be blamed on this medication before people begin to blame you and not the shot... I gained maybe 3-5 pounds, my feet swell and sometimes my hands... the worst thing has to be the hot flashes and night sweats. At 27 years old, and as someone who used to be cold all the time, I can't take the constant sweating and feeling like my hands are on fire. I've only gotten my period twice this year (due to another hormone therapy before this shot), and when I had it once on Lupron, I bled for a week and spotted for an additional 2 weeks. It caused an infection, and the odor was so offensive that I couldn't stand to be near myself. That one cleared up, but then I got another infection less than 2 weeks later.

For me, this shot was not worth my time or effort. I'm going off all hormone therapies and I'm just going to deal with the symptoms I have and get on with my life.

I just went in for my second shot of Lupron (out of a series of 6) for treatment of stage IV endometriosis. The most noticeable side effect I experienced was during my first menstrual cycle after my first dose of Lupron. I had never experienced menstrual pain or cramping (even though I had advanced endometriosis) until after Lupron. I have a fairly high pain tolerance and yet the cramping for the first 2 days of my period were almost debilitating. I had extremely heavy bleeding and have had spotting daily ever since (app.18 days). I have gained about 3 pounds because I have no energy at all. I'm usually active and work out 4-5 times a week but by the time I get off work, I'm too fatigued to do so (hence the weight gain I guess). I have hot flashes and night sweats all the time. The most recent side effect is high blood pressure. I have never had high blood pressure in my life (I'm a healthy 25-year-old woman) and when I went in for my 2nd Lupron shot today, they told me I all of a sudden do. I don't seem to have mood swings but do feel depressed and sometimes more anxious than normal. I have experienced a decreased interest in sex as well.

I've been searching for answers on LONG TERM side effects of Lupron hoping that it could give me answers as to what's going on in my body now!
23 yrs ago my fertility dr. gave me Lupron to inject MYSELF EVERY DAY (experimental back then). I had SEVERE endo since the age of 16 and was fighting that as well as trying to get pregnant thru invetro. I was 26. At 29 I had an emergency hysto. Now at 48plus I have chronic tendonitis where the tendons will shred off of the joints. I have been diagnosed with C spine and T spine disease, osteoarthritis and a mystery that I'm going to have to go to the Mayo to figure out (hopefully). I have tumors that are growing in my lower back...growing around nerves, tendons and bone, They aren't sure why they are there, why they are growing, or even what they are. Surgery removed 2 of them...but pathology shows foreign matter other than tissue/bone. All they DO know is that it is not cancer. One year ago I started losing weight (25 pds) for no reason. I'm now holding my own at 112 and hoping to figure all of this out. I can't help but wonder if Lupron or any other experimental drugs I was on has something to do with this. Is there anyone out there that used this drug so long ago??

I was prescribed Lupron after a laparoscopy to diagnose endo between my freshman and sophore years in college. I was never told of any psychological side effects, even though the first page of my chart has a lot of info about my history of depression and anxiety. In addition to the night sweats and hot flashes, the depressive side effects were so bad that I dropped out of college (I was a stright-A student the year before.) It took me 2 1/2 years to get back to school, and I'll be paying off the $12,000 for a semester that I spent almost completely in bed. I'm a nursing student planning to work in women's health care, and will advise any of my patients to seriously research this medication before listening to their doctor. My pain never did go away while on the medication and was actually worse later and caused me to go back in for surgery.

I have endometriosis and chronic migraines (not related to the pill). I am taking a preventative migraine medication daily now, so we figured we would try again to help my pain from the edo with the pill. At this point, all of my doctors have suggested taking lupron, which will put me into temporary menopause, instead of the pill. I am just not ready for that option. Because I have tried so many different pills, Femcon FE is one of my last options before taking the lupron. I was concerned after reading many of the posts on this site, but figured I would give it a try and see. I started it on Sunday April 25th and so far this is what I have experienced:
Increased onset of migraine pain- (but the pharmacy didn't have my migraine medication and I had to wait two days until they ordered it, so that could be the cause of that)
Slight breakout- (but I started a new foundation, so that could be the cause of that)
Increased moodiness
I have not had any cravings like I did on Seasonale (all I could think about was chocolate)
I don't know if I have had any weight gain yet, my scale is out of batteries and I haven't had a chance to replace them! But my cloths do not feel tighter, so that is a good sign!!
I will continue to post periodically while taking Femcon FE. Hopefully it works for me and I will have nothing but great things to say! I am going to stay positive and will away the negative side effects!!!

I am 26 years old and I was diagnosed with endometriosis last year (2008). I had pain in my lower abdomen for years and doctors always told me nothing was wrong but I knew there was. Finally a doctor did an ultrasound and found a 7cm mass on my left ovary. I also had a slightly smaller mass on my right ovary. My doctor told me that he would need to do a lap to remove the masses and possibly remove my left ovary because he could hardly see any ovarian tissue on the ultrasound. Thank goodness when he did the lap I was able to keep but ovary but he told me that I had one of the worst cases of endo he had seen. My right ovary was stuck to the wall of my abdomen due to the endo and I even had endo on my bowel. He removed what he could but not all of it was removable. He suggested that I go on Lupron for 6 months to "shrink" the rest of the endo. I have been on Lupron for 3 months. I just went and got my second 3 month injection. I have had some side effects such as Headaches, Bone pain, Hot Flashes, Insomnia, Drowsiness, Increased appetite and major Mood Swings. All of which come and go. I try to stay active but I don't over do it. It seems to help with the joint pain. Most of my side effects were in the first 2 months of getting the injections. I am told all the time that everyone reacts differently to Lupron and there is a pill you can take to reduce the side effects of Lupron but it does reduce the effects of the Lupron so my doctor suggested that I not take it unless the side effects were unbearable. I don't remember what it is called but if you are one of those people having major side effects ask your doctor.

I have endometriosis and would like anyone with the disease to contact me so that I can find out more information, etc. My email address: ******

I can relate to many of these experiences. Started out in my 20's with very irregular cycles, went to my first gyn after a miscarriage - the emergency room dr referred me to a dr that was at a fertility clinic. I had no idea why until I was actual a little more "awake" I was diagnosed with polycystic ovaries. I went through at least 6 or 7 different birth control pills, depo provera shot, nuvaring, then back on another birth control pill. finally we started doing the continuous suppression as I was bleeding at least a little bit every single day... for 2 years. I would still have my full blown period every 4 weeks or so, which also included a monster migraine on day one of the menstruation. Not only was my life being altered but I was starting to get anemic. Finally after a month of the continuous suppression my bleeding stopped. As did the menstrual migraines. I continued this way for 4 years. Didn't have a single period or migraine, life was wonderful.. or so it seemed. I have been over weight for most of my adult life. Finally decided to do something about it. I joined the gym with a friend and started losing weight. I dropped 55 pounds until... the dreaded bleeding, pain and hormones got out of control. I started bleeding every single day again. Finally made an appointment with my dr. She stated that when you lose weight it releases estrogen out of your fat cells. Gee, I thought losing weight was supposed to make you feel better!! I went on with it for a while thinking it would stop eventually and it just HAD to get better. In fact, things got worse. I started having horrible abdominal pain, eventually it got to be daily. To the point where I could not stretch or even hyper extend my right leg backwards. My abdomen felt like something had a rubber band tied to it from the inside. My dr said that she suspected endometriosis. However, due to my anemia... we had to wait. So back on the iron pills and wait wait wait. Finally, October 15th I went in for my lap. Sure enough, stage 4 endo, huge cysts on both ovaries. My endo had gone all over the place and attached itself to anything it could. Including folding my bladder in half! Good grief. I thought that I was just getting the weak bladder from getting older (I am 35 by the way). For the next couple of weeks after my surgery I felt pretty good. Finally pain free (still a little bleeding but not much). But, the end of December rolls around and here it is, back with all its fury. The pain is again horrible, my migraines are back, my energy is dwindling. The good life was short lived. My doctor suggested a series of Lupron shots. One shot a month for 6 months. My first shot in January (took me a little bit of time to decide if I wanted to do it) finally bit the bullet and got the shot. First few days, fine, no problem, no relief either but no life altering experience. Then one morning I woke up and realized I was not in pain. It was a strange feeling actually. But the time I got the second shot, no more bleeding, no more pain... However, the hot flashes, night sweats and the emotions came on. Holy cow. Drama drama drama. I could find any reason on the planet to argue, with anyone. Thank god I have a very understanding family and an even more wonderful partner. I think he has the patience of a saint. I still don't know how he puts up with me. If I am not trying to find some reason to pick a fight then I am crying like a baby... for hours and hours. These hormones are so out of control. I honestly don't know what is worse, the pain or feeling like the world is going to end in the next 2 minutes if I don't get this spill picked up.. I literally cried for 2 hours Saturday because my cat knocked a stupid bottle of car wax off a shelf in the back room. Good lord, I had the most horrible feelings coming over me and just could not stop crying. I bought a new bed 2 weeks ago and let me tell you. If I am not on one of my 13 hour sleep fests then I am laying in it crying and feeling sorry for myself. Or the even better part of indegestion or my favorite part.. gas. I honestly don't know if I can go on like this. I made an appointment to see my doctorr this Friday to determine what she thinks will happen if I don't complete the other 3 shots. just give me back the pain if you have to!

I am 31 years old and I FINALLY have relief from the pain caused by endo. I have been dealing with this crap for about 14 years. I have only been on it for 1 month. The hot flashes are TERRIBLE!! But I guess it beats the pain. I have been reading some of the other people that have posted their side effects. Some of you are saying that you have been on Lupron for 1 year or even 2 years. My Dr. says you can only use if for 6 months. I guess I should've asked more questions. Any suggestions on what to do about the hot flashes - other than put a fan in my face??

I have just sat here and cried listening to your story and your side effects! Finally, I feel like someone gets what I've been going through! Hell! I had Mirena put in this past Aug. '08 for heavy periods and cramping after surgery in March for endometriosis (my 5th) and then two session of the worse drug in the world, Lupron. The Lupron had already made me gain weight and then the Mirena came along and made me gain more! I have taken 4 pregnancy test in the time I have been on it. Really convinced at times I was pregnant. I felt so bad, so tired, nausea. That was basically the whole months of Nov. and Dec. Now I have acne which I've never had, still horrible cramps, cramps in my legs, my period are back to every month, my pms is horrible. I can barely get out of the bed, I am so tired and when I do I can barely keep my eyes open. I feel like I have been hit by a truck. Cramping all the time! Headaches. I'm so swollen! I feel in a fog! People will be talking to me and I have know idea what they are saying. It drives you crazy, like you are just in another world! Insomnia. Just feel miserable especially, when I'm about to start my period. I've started spotting again. My periods are heavy again and I have huge blood clots! MY breasts are engorged! Huge! So uncomfortable. I've felt so alone. My doctor said this will be so great for you because it will eventually leave you with no periods, which will help with your endometriosis pain, but I'm really not sure that will ever happen! People don't understand how hormones can make you feel so awful! I have a 2 yr. old and I feel so guilty being so tired and feeling bad all the time! I just want to fell good for once since I've had him. It is the worse feeling when they just dismiss what ur saying to be something else and I'm smart enough to know and know my body well enough by now, with all the crap I've been through to know when it is the Mirena. Thank all of you for sharing your stories and making me feel that I'm not alone anymore!

I am so glad that I found this site and to see that there are other women out there who are having problems with the Mirena. I thought it was just all in my mind! I had the Mirena inserted in February 2008. Started having problems with high BP when pregnant with first baby and when I went back on pill after his birth BP wasn't doing any better. After having my second child, I contemplated about Mirena vs. having tubes tied. My OB said the Mirena was the perfect thing for me and was pretty much like tubal ligation, but without the surgery. I had no problems when Mirena was inserted..just bleeding (seemed like forever for me to stop bleeding) and the normal dizziness. For the first three months, I never knew when my period was going to be, but I just kept remembering what my OB said "your periods will be like nothing after the first three months." My periods did get a little better...however not the "light" or spotting periods. After the first three months, I started noticing that my hair was starting to fall out more but thought it was part of postpartum. I started feeling really tired, skin started to break out, felt depressed, my mind was racing, couldn't sleep, had problems remembering things (simple things), migraines got worse and more frequent than what they used to be before, moody, agitated, had chest pains, nausea in the morning (at one point I thought I was pregnant again!), stomach pains, diarrhea/constipation, kept having vaginal discharge (like when you are pregnant), came down with bacterial vaginosis, UTI's were somewhat common,no sexual desire and my BP was out of control. Seven months after having Mirena inserted, I started having sharp pains near right ovary. I had problems with cysts in right ovary before and had them removed so when the pains started, I had a hunch that most likely it was another cyst. My OB closed her practice so when I went to new OB for annual pap, I mentioned all the things I was experiencing including suspicion of cyst. I told her I had been experiencing all symtoms since Mirena was put in. She told me that she has never heard of the Mirena to cause symptoms like these. Told me that perhaps I was still having effects of postpartum and that my body was trying to get "back to normal" and get used to Mirena. Had all these blood test done and everything came back normal. I did have a cyst on right ovary and was told that it should go away within 2 months. Just had a follow-up ultrasound today (2 months later) and cyst is still there along with other cysts on right AND NOW left ovary. Most of the time, I am in a lot of pain especially on the right side. I was told to just take Motrin for the pain, but that nor heat packs work at all. I am really considering to have the Mirena taken out. I REALLY believe that the Mirena is the cause of my cysts. Is there anyone out there who have gotten cysts while with the Mirena? And has anyone experienced having no problems with cysts after the Mirena was taken out? Since finding out that I have multiple cysts on both sides and knowing that my doctor will probably tell me they will eventually go away on their own (first one is less than 2cm and others are smaller), I don't know if it is even worth keeping the Mirena in. I hate having all these symptoms...I just want to be "normal" again. BUT, IT IS VERY COMFORTING TO KNOW THAT THERE ARE OTHERS WHO ARE OR HAVE EXPERIENCED THE SAME. Now I can tell myself that it is not all in my mind and I am not going crazy!

I haven't been on this site since about 7/08...and I am sorry to hear of all really crazy, uncomfortable side effects that many women have experienced. I had the mirena put in 3/15/08. It was recommended by my doctor because I have stage 2 endometrosis.
Overall, I would say that I have adjusted pretty well. My symptoms were and still are: occasional dizzy spells (less than a minute), some occasional tingling in my hands when I wake up (as if I was laying on them when I was asleep but wasn't), and I have had 2 REALLY heavy periods, the first was about 3-4 months after it was inserted. I bled for 3 days straight and was using super tampons and pads and was soaking through them in less than 30 minutes. I called the doctor on the 3rd day to see if this was "normal". I was told it usually takes at least 6 months for your body to adjust. At this point, I still have breakthrough bleeding for about 3 weeks a month and need to use pantiliners about every day as a "just in case". I still get my period but it is definitely shorter and lighter than before and most noticeably, less painful cramps overall.