Major depressive episode symptoms and conditions

I've been on and off singulair for several years. I had a horrible bout of bronchitis that then triggered bronchial reactive disease and I now have allergic reactions to certain chemicals (some spray deodorants, etc.) Singulair worked so much better for me than advair, I was thrilled to be able to talk and breathe. As a teacher I would sometimes have to stop the lecture to get my breath again and drink some water if I inhaled the slightest amount of chalk dust or something.

After reading the comments on this website I am going to discontinue taking singulair. I used to be this skinny person and never, ever worried about my weight. At the age of 37 I had a rip-snortin' major depressive episode with insomnia that had me miss 3 days of sleep (this is on no medication of any kind) and panic attacks and suicidal thoughts and impulses that I'd never had before. Imipramine was my first prescribed med (in 1991) and worked like magic. It cheered me up, calmed me down and made me sleep. I went from 135 pounds to 155 pounds in just several months. I finally got switched to effexor and trazodone, but there's really not been much weight loss. I'd hover around 150-160, but then with singulair added in the last several years I am 170 lbs. I can't believe I am a fat person now and do not over eat. I can't go off my psychiatric medication because it runs in our family and if I taper off I am...uh...crazy. My insomnia is tenacious when I am without medication and then that makes depression and anxiety worse. I never want to have a panic attack again.

I just ran out of my singulair prescription about a week or two ago. I am breathing and speaking fairly normally and my husband and I now have to pay for our own health insurance which is exorbitant and I just didn't feel like renewing the prescription in order to save money. I was pondering my weight gain today and just decided to google singulair and weight gain and I just can't believe it.

I have also experienced hair loss, but my hair is so thick it still looks basically the same. My husband and I have noticed over the last several years that I lose lots of hair after I wash it and there is a mass of hair in the shower stall.

My memory may have been adversely affected by taking singulair. I thought it's just getting older. I am 55. It's been the last several years that I have started to have problems remembering things. I have always had to work with my husband in helping him remember things (it's been life long with him: he is an absent minded professor. He has a genius IQ, is an M.I.T. grad, is an excellent engineer and can't remember his mother's birthday, what plans we have for the week-end, no matter how major, etc. to save his life.) I feel like I am becoming more like my husband in being hopeless and helpless about remembering what's happening from one day to the next. It could very possibly be the singulair. There has been a marked difference in my memory over the last several years. It is embarrassing. I sub for the school district and once showed up on the wrong day at a school and another time didn't show up and they had to call me up and get me out of bed to go to work. I also teach piano and never used to forget who was coming when. Again, I don't know if I can blame this on singulair causing memory loss, but there would be times when someone would knock on the door and I'd be surprised to find a piano student standing there. I feel like I am getting Alzheimer's. My grandmother had it for 17 years. My mom has always been afraid of getting it but she is 80 and is just now starting to show signs of real forgetfulness. I explained to her what my lapses in memory are like and she is shocked to hear that they are similar to hers. My mind just will completely go blank. I will have this thought, get distracted, and just a moment later will struggle to remember the previous thought and there is just a void, peace, blankness, white screen in my mind. Maybe it is getting older, but maybe it's the singulair. Since I'm just recently off it I'm going to pay attention and see if my memory improves or if it is just old age.

Also, my joint problems have been nearly ruining my life the last several years. I don't know if this is exacerbated by my singulair use or not. Bursitis in the hips runs in my family like crazy. We re-sided and painted our house several years ago and my bursitis started to flare up and has been bad since then, but it's also about the time I started taking singulair. I had to quit a sales job this summer because my bursitis has become so bad. Sometimes I can hardly walk. It is nearly unbearable. I get cortisone injections every 6 months, but need it every 2 months. I wonder if my discontinuation of singulair will ease my joint pain? I'm going to track that as well.

For me: weight gain, hair loss, joint pain, some dizziness are possible side effects from singulair.

Thank you to everyone who has contributed to this site. I am never taking singulair again.

The first time I took Zoloft, it was a brand new drug with a high price tag and people were just beginning to talk about depression--openly. I had a positive experience with it. I have PTSD and severe depression due to trauma as a child and later from an abusive husband. I had a major depressive episode shortly after the birth of my 2nd child, exasperated by postpartum depression and thyroid storm. I became suicidal at a time when I seemingly had all I ever wanted. It saved my life in that regard.

I had stubborn baby weight that needed to come off. Also, I tend to be an emotional eater. Zoloft helped curb my emotional eating and I lost weight. Some people say overeating or eating disorders are akin to OCD behavior, both anxiety based, so in that way it makes sense. When Lithium was added, then changed to Depakote, I had a tremendous weight gain--I was PUFFY! At that time Bi-Polar was the flavor of the month--not that it isn't real--it just seemed that at the time, everyone was BiPolar. I later went off all meds and was OK for about 3 years when the ugly beast reared its head again.

Zoloft at one point both saved and ruined my life. The first time on Zoloft as a young wife and mother I think the verdict was still not out with all the side effects. I was unable to engage in sex. Not only did I not have any sexual urge but my body couldn't. I talked to a therapist and psychiatrist to no avail--it was MY problem--that the birth of a child brought up abuse issues--men are the only ones with sexual side effects! After being sexually NORMAL my husband and I were told that it was psychological. That didn't do a lot for our relationship. It also made me more distant and quiet. The new Me-on-Zoloft was like my repressed alter ego. The new me was all the more reason to need to stay on meds--just see how depressed and troubled I am. My husband and I divorced due to bad medicine and I didn't know any better. Had all the information been out there at the time, things could have been different.

I went back on Zoloft with mixed results. As a creative writing major at the university, it was like someone flipped a switch and all creativity left me. I found it increasingly difficult to concentrate and recall information for discussion or tests. I was however , more focused in the mundane--dinner, dishes, laundry, regular exercise, all the routine stuff. The anxiety before going back on zoloft made me want to rip my hair out and I was overwhelmed by everyday stuff. I would wash a dish and fight the urge to run around the table before washing the next one. Part of that, I think, was the pressure of being a single mom with 3 small children, going to school full-time and working part-time. Whew! and with little support from anyone, no dad in the picture.

Through the years I have been on many other things and this will probably be the pattern for the rest of my life. Paxil made me a suicidal zombie to the point that my kids cried and made me go to the hospital--they didn't know the suicidal ideation at the time. Effexor caused flabby weight gain and myalgia. Last year I went in the hospital again for depression (job loss, 2nd divorce, mother's death & all at once). The psychiatrist talked me into going on Pristiq claiming it was like Effexor but with none of its bad side effects. BS!!! Once again, I was duped and still weigh 33 pounds over what I did. I am AGAIN back on Zoloft and it seems fine. The devil you know is better than the one you don't know--I guess. I haven't been back on it long enough to know what will happen this time but it can't be worse than the other things out there. I'm tired of being the psychiatric community guinea pig. Everyone is different; my best friend gaied 25 lbs. on Zoloft and takes Paxil (I can't), my sister only does well on Welbutrin, my friend's mom has been on Effexor for years and it keeps her sane. You just have to find your fit. My problem has been from the medical community not being forthcoming with information and the reluctance to listen to a 'crazy' patient.

The medical professional is particularly unhelpful in this matter. Talking with medical personnel about fluoroquinolone poisoning is a go-nowhere exercise. In an era when Monsanto genetically-modifies our seed stock you might think medical caregivers would advise us in advance that their prescription antibiotics mess around with their patients' DNA. (IT's that deregulation thing, yes?)

I experienced painful calves and a strange dream, possibly a nightmare, immediately, e.g., on the very same night, after having injested one Levaquin dosage for a prostate condition and maybe a year after separately having taken cipro for a week to combat traveler's diarrhea. The post-Levaquin early evening dream was strange insofar as I rarely drempt, and I never recall having been roused to wakefulness by a dream shortly after having gone to bed. Early on I did NOT associate Levaquin with the really terrible symptoms that I experienced within 60 days of having injested Levaquin.

My wheels fell off when I entered a period of insomnia. I thought my sleeplessness was stress-related because my health history includes a major depressive episode 11 years ago. I presented myself for help to a psychiatrist who prescribed a small dose of an atypical antipsychotic as a sleeping aid. My drug-induced sleep felt like a coma that lasted each night for a couple of hours. There were heart palpitations, agitation, panic attacks, racing heart, racing thoughts, insomnia, depression, paranoia, poor cognition, body shuddering, muscle twitching, night sweats, and pain in both Achilles heals. The symptoms filled a note book page. I felt like Jean D'Arc who was being burned chemically at the stake from the inside out. I would rise in the morning and then minutes later fall back into bed. I could stare off into space and completely lose track of time. I could not even find the right words in mid-sentence. I could not fill-in the registration papers when I presented myself for a second opinion at Mayo Clinic. I became a full babbling idiot. My wife said that I had retreated or devolved into some kind of primate or ape who communicated solely his emotional states by means of eye contact only.

I asked my doctors if the sum of levaquin and cipro had pushed me over my peak quinolone tolerance level. Or was it the medicine that the psychiatrist had prescribed to make me sleep? . I was no stranger to depression and I knew my symptoms were not merely emotional or psychological in nature. Why did I always feel as if I had been poisoned? The psychiatrist decided my paranoia warranted higher med levels. I declined the advice and stopped taking the meds altogether. My anxiety today is lower, my sleep is improved but fitfull. My neck aches. My head feels as if it were in a vise. It's not a headache and it's not painful, but there is a tingling, crawling, scorching sensation at my forehead and behind my eyes as if someone had beat me with a pillow and then filled my head with novocaine.

I'm not sure there's a moral to the story. It might sound a tad over-the-top, but I think we're faced by a pharmaceutical plague. There's really no excuse for the absence of informed consent. There is nowhere above ground, e.g., nowhere on main street, and no-one with whom you can speak in order to take the full measure of fluoroquinolone poisoning. If you are at this URL merely to find out about the FDA's recent black box warning re: Levaquin's link to ruptured tendons, you are in for peep into hell. Read the other thousands of postings on this site, and decide for yourself who bears the ring of truth.

Please add me to the list of people with an extremely adverse reaction to Singulair. I had been taking 10 mg Singulair since 2005 after sinus surgery In June 2008 after returning from vacation I didn't get my prescription refilled in a timely manner and went without it for ~one week. In July I got a new prescription filled for Singulair and also began taking Advair Diskus 250/50 and AllegraD after an increase in asthma symptoms. I first thought the anxiety attacks were from the AllegraD as the "D" is for decongestant and contains psuedo-epinipherine. But the anxiousness continued and got worse after stopping the AllegraD. I then stopped taking the Advair (and also a nasal spray that I use called Flonase also since 2005) but was still in a major depressive episode with daily thoughts of suicide. It wasn't until I stopped taking the Singulair on August 23 that I started to return to normal. My normal does include a history of depression for which I take 10mg Paxil daily. Like the post from the psychiatrists wife noted, I am not sure if there is a direct scientific connection between these events. I do know that I never want to go back to that place I was in. I am shocked at the speed with witch I started to feel good after stopping the Singulair. I still have low grade sad feelings but I have stopped planning my own death. I always took my dose of Singulair in the morning and ~one hour later would begin to feel anxious. My evenings were tolerable with emotions slightly better. I simply stopped taking the medication without tapering and I am beginning to deal with what happened to me. Thank you all for sharing. Thank you.

On my posting the other day, I forgot to mention the sweating, day and night. I thought I was having hot flashes from hell but now am seeing from many of the other people that it is a 'normal' Paxil side effect.
For as much good as this drug can do to help you through a major depressive episode, I don't know if I can say it's worth it. I lost my ability to have normal reactions to sad events and could only cry when I saw a really sad movie. You could tell me my home burned down and I wouldn't have cried. This is some weird stuff and I think I like feeling my emotions better than having them masked.

I had a hypertensive crisis in early July. I went to the Doctor for a history and physical for pre surgery on my knee. I had been in severe pain in my knee since March.. The doctor found my blood pressure to be 200 over 108. I had been put on Toprol XL50mg, 1 & 1/2 tabs at night,(of which I was only taking one tablet) and 10-40 mg. of Vytorin the previous year by this doctor's partner, (and wife) for mildly elevated blood pressure. On May 25th, my psych, who treats me for ADHD and mild depression checked my blood pressure in her office and it was normal. 120/75. This doctor then Doubled my Toprol, Added Lisinopril and postononed my surgery. I told him that I had been in angony and felt that this may be causing my spiked blood pressure, as I tend to do this. Less than three days later I was admitted to the hospital through the ER with high blood pressure and tingling in my arms and wrists. The doctor added Norvasc to bring down my heart rate and Klonopin to control my anxiety. After many difficulty and expensive tests, he concluded that I had high blood pressure due to stress from pain, medications, and a problem with anxiety. I had my surgery and am recovering nicely from my knee pain. I saw my psych, and she put me on topomax and trileptal to control mood swings. I am now into a full blown major depressive episode that I believe is being caused by any or all of these medications. None of my doctors have time to talk to me or want to help me. They only see things from their specialty. I am so frustrated and angry. Has anyone else experienced severe depression with this lisinopril. I need to get my life back!!! This is a bad Drug!!!

I recently started Lipitor, and within two weeks had a major depressive episode. I have not had any such emotional outburst for years. My sister asked me what was different, and the only answer was Lipitor. I will not live like this. I will gladly drop dead from a heart attack before living in misery forever.

I started Lamicatal May 19th, 2005. I was warned by my doctor of dangerous rash and itching. If so, stop taking medication, call him if not too bad that I need to call 911 to go to the hospital. On my print out from the CVS pharmacy is clearly stated: Serious (sometimes fatal) skin rashes have occured while using this medicine. Immediately notify your doctor if you develop any type of rash. If this medicine is the cause of the rash, the medicine must be stopped. Even after stopping this medicine. It is still possible for the rash to cause permanent or life-threatening scarring along with other problems.

Possible Side Effects:
drowsiness, trouble sleeping, dizziness, nausea, vomiting, loss of appetite, muscle aches, double vision, blurred vision, fatigue, weakness, headache, shakiness, or clumsiness.

Symptoms of an Allergic Reaction include:
rash, itching, hives, fever, swollen glands, swelling of the lips or tongue, painful sores in the mouth or around the eyes, severe dizziness, or trouble breathing.

Symptoms of Overdose:
may include unusual dizziness, serve headache, unusual sleepiness, involuntary eye movements, and loss of consciousness.

I starting itching really bad the second day on the medication. To the point I had huge bruises allover me. I got a spurt of energy that I have not had in several years the second night but not since then. I can't go to sleep at night. Even taking 6 Tylenol PM and a Klonapin I don't get sleepy until around 9 to 100am in the morning and then I sleep all day long. I have started to have frequent headaches, suspious bumps around my mouth area. My muscles ache, too. It is Memorial day weekend so I can't call my doctor but I am going to on Tuesday. I have (MDD) Major Depression Disorder, Manic Depression, (TRD) Treatment Resistent Disorder. Nothing I have taken thus far has helped me with my depression.

Does anyone have first hand knowledge on ECT treatment? I am seriouly considering this procedure. I am desperate but I have no insurance or money because I haven't be able to work for 9 years now. This is the only thing that has kept me from getting the ECT treatments, is money! I have contacted every Talk show, hospital, clinical trials and no luck in finding free help with ECT.

Any ideas, guidance or suggestions would be most appreciated, I am dire to get help soon or I won't make it.
Sincerely,
Lost Hope