Manifestation symptoms and conditions

I am an intensive care physician , one day we got a 75 year old male patient for acute allergic skin manifestation and general body swelling , the patient has been taking Lamictal tablets for seizures control after brain surgery few months before his presentation the patient was put on i.v steroid therapy along with antihistamine, on the second day we noticed that his skin is peeling off and his breathing got embarrassed , the case was diagnosed as( TOXIC EPIDERMAL NECROLYSIS) which is the most severe form of drug allergic reactions as a side effect of Lamictal administration , one week later the patient died due to acute respiratory failure (ARDS) however he was on mechanical ventilation support.

HI guys I was given pred at 60mg then over the next several weeks I tapered off. it is now about 3/4weeks since I took the last tablet. Whilst i was on them I developed quite bad hand tremors/shakes and since taper off to a low dose I have started with muscle twitches all over. Has anyone had experiences like these? And how long did they last?

hi guys! about four months ago my doctor switched me from ortho tri cyclen lo(which I had been on for two years) to yasmin. It was the worst experience I have ever had in my entire life. About a week into the medicine I started getting horrible headaches, terrible anxiety and suicidal thoughts. I was sooo scared from this medicine that I stopped taking it thinking that everything was going to get better! Well wasnt I wrong. I developed OCD really bad to a point where I would sit and worry that I would hurt someone I loved or that I would hurt myself. and I had disturbing thoughts in my head that made my anxiety worse. I have been off the medicine for like 4 months and I am now taking 50 mgs of zoloft for my OCD, anxiety, and depression. I am unsure that it is working yet it's only been two weeks! I hope and pray eveyday that I finally start feeling myself! It's been horrible! Has anyone had this experience from this medicine? and if so do you think that I should get a hormone test, because I am almost convinced from reading other posts that my hormones are wacky! Well thanks for reading! and I hope everyone feels better! :)

Reading all of your your sx's was both heart-breaking and eye-opening. I have been on Topamax for 4 months--just moved up to 100 mgs in the hopes that the migraines would be defeated once and for all. So far, besides a week-long doozy that I think was actually a horrible manifestation of the stomach flu, the headaches have reduced themselves to about two times a month rather than averaging about every day. An improvement. Never-the-less, I still wrestle with the choice of the depression that has followed me like a black cloud since I began this therapy, and also the rage that can blow up out of nowhere, or the headaches. Quite a choice. I often wonder how my children will remember me. I'm not normally a moody, angry person, but since starting Topamax, you wouldn't know it! Not surprisingly, my doctor simply offers me an array of more prescriptions to add to the cocktail. I've had about enough. I too get the tingles in my hands and feet--especially if I've been sitting with my feet elevated--like in an easy chair. I'm getting good at ignoring it, though. It's actually quite painful! My face quit tingling after the first month. Words can still elude me at embarassing moments. So frustrating! I lack all ambition, and I must literally force myself to do anything--housework, exercise, take care of my children! Guilt, guilt, guilt! I'm so glad that so many of you mentioned that! I've been beating myself up about that particularly, wondering what in the heck was wrong with me! I could sleep all the time! I've lost about 8 pounds, and my appetite is satisfied very easily. Carbonated beverages don't taste horrible, exactly, they just don't taste good. So I've more or less quit drinking them. No loss. We spend less that way! As I read all the entries, one thing is very clear to me. We have got to be less passive in the hands of our doctors. No one knows too much about this drug. There are alternative forms of medicine that are being more actively explored by reputable practitioners. I am starting to research it more myself. I don't want to live out the rest of my days so...sad. And angry! Good luck to all of you.

To the mother of the child for whom Neurontin acts like speed:

Neurontin takes away irritability (or nerve-firing threshold) of the involuntary muscular system, and it sounds like the physical phenomenae is just another manifestation of the seizures for which she had the drug prescribed.

Poor kid, those side-effects sound TERRIBLE, and as her mother I would immediately talk to her doctor about change of dosage, or something else -- anything else -- the effect N has on her shows it's either not the right thing for her problem, not enough dosage, or another not-yet-understood indication of inappropriate treatment. The fact that she has headaches indicates it's not just her Mom's unwillingness to deal with a hyperactive kid. Having-headaches means it's poisoning her system. Please act as her advocate and protector in this matter.

And it's NOT the last-ditch treatment for seizures: ask her medical team about surgeries. If they won't do that, then either find new doctors who will give you access to everything possible that modern medicine can provide to help seizures, or explain the trade-offs of living with medicinal side-effects and the risks of surgery.

Jan S. Kauffman, Neurontin userid, parent and grandparent, Masters in Counselling, certificate in elementary education, survivor of decades of fighting the American medical system

i began taking allegra regularly about two weeks ago and about that time an itching srea began on my right hip. now the itching hs spread to the back of the thigh, across my buttocks, the left thigh, and it has caused many sleepless hours. my new dermatologist said it was only dry skin that had to be rehydrated, so he sold me lipocream and gave me a prescription for halog. neither of these have been of much affect so far.]this the second day. he advised luke warm baths, certain soaps, etc. the rash has not diminished and is more like whelps, than eruptions. i am 74
and never had this manifestation caused by "dry skin". is it possible i am allergic to allegra? anyone can help!!!