Massive doses symptoms and conditions

I have been on prednisone for 11+ years due to having had a heart transplant. The prednisone keeps my heart from rejecting.
I have not taken it for 2 days and I am in the process of passive suicide.
I am driving out west into the desserts to sit and die. I can no longer
be around people for I am afraid I may kill someone or at least significantly hurt them. I have been homicidal and suicidal for 11 years due to this med. I would enjoy killing everyone and everything. I hate myself and I want to die.
Prednisone made me become "Evil"; Hell incarnated. I don't want to live
in a mental institution and my doctor will only give me Seroquel thinking this will help me. I tell him it doesn't help me but he thinks it does. Stupid fucking doctor. My transplant docotrs won't even listen to me when I talk about "mental" issues. Everything pisses me off. It is raining outside and this makes me so mad and stressed.
I have been in this psychotically angry and agitated state of mind for 11 years. I have punched myself many times in the head and banged my
head against walls trying to get homicidal and suicidal thoughts out of my mind to no avail.
I would like to try ECT (electro-convulsive-therapy) but I won't even
mention this to my doctor because he will literally laugh at me and make me so god dam mad that I would enjoy killing him right then and there. I'm sick and tired of living in hell everyday.
Do not take prednisone no matter what, unless your life depends on it. And then what type of life will you have? Maybe a life full of hate, rage, anger, homicidal and suicidal thougts even when you dream.
Fuck life!
Arthur X 1968-2009

i have been on vytorin 10/10 for 2 yrs.Last year i started having multiple symptoms.Nausea,loss of appetite,virtigo,and now anxiety issues.i have been to cardiologist,ear doctor, neurologist,eye doctor, and had many tests and they all come back normal. I have concluded it is the vytorin maybe?i stopped 3 weeks ago and haven't felt this good in months.my energy is up and im starting to feel like my old self again.my doctor wants me to go 3 months on no meds to see what happens.at that time id like to try omega 3 and red yeast ice? anybody had good results with any of these? im 51 and in great health other than cholesterol of 250.

I'm 52 yr old female with high blood pressure and asthma. About 4weeks ago had bronchitis with massive doses of prednisone. Around the end of the prednisone my doctor switched me from enalapril to lisinopril to better control my BP. Well after the Prednisone my knees felt better than they've felt in 3 years NO pain. I 1st started noticing the leg cramps when in bed at night. Now the cramps are 3 to 4 times a night waking me up. 3-4 days ago my knees started hurting again, to the point I have to brace my (R) knee even at rest. I can barely walk. So I decided to look at my medications as a source of my pain. Calling my MD on Monday. Switching back to Enalapril until then

I have had so many shots of
Corticosteroids/NSAIDS/Steroids:

Triamcinolone Acetonide, Kenalog, Depo-Mardol, Lidocaine, Marvaine, Toradol, Epinephrine, Bextra, Xylocaine, Isovue.......on and on and now I do not walk hardly anymore.

I am married, no sex whatsoever! I stayed away from my husband for 3 years almost, living at my apartment. I just moved out by Eviction March 2, 2008. I did not pay rent for one year. I applied for disability since 1995. Won ALJ decision September 2006. I appealed the case being opened back to 1995. I wanted it go go back futher. Just appealed it again in 2008.

Okay, I am a simpleton out here needing a HERO to Take A Stand and Advocate for me.

I do not live with my husband. I live at his mother's home so that he comes and takes cares of us at the same time. She is 90 now. Can you imagine this? I have been reduced to a cripple.

I am a prisoner laid to rest by the BIG DRUG COMPANIES MISLEADING ME, IN NOT KNOWING ABOUT THE DISEASES THAT WOULD ATTACK ME IN THE ONLY LIFE THAT I HAVE.

I wonder if my hip bones have collasped. I have terrible bone pain.

I waddle like a duck, side to side with extreme pain until I freeze up and fall, but mostly, I live with a cane at my side when going out and about.

I now need a wheelchair.

From 1980's, 1990's and now all the way to 2008. I have all medicals.

It was not until 2003-2004 that my life took a turn for the worse.

Hips pain, arms pain, shoulders pain, pain in the Thorasic area to the tail bone area, right groin pain/pubic area pain/gentials, stomach sores/cut out, pain on the scalp, calves feel hard in side/stiff at all times, hamstrings are short,open sores have been on my face, arms and neck lasting for 4-6 mths, low back pain....all of me has been injected with the above crap.

I was doing quite well in life until 2004 when this Orthopedic doctor had shot my left shoulder 3 times.

After this June 2004 event above, and by September 2004 I had walking problems, blamed only on Fibromyalgia, DX 1989.

They took one blood test for Polyrheumatica.

I was fed 20 something meds in 2004.

By 2005 I was devestated in life, health and even wanting to be alive. For one full year I lived on the pot, using Lidocaine up the butt 3-4 times a day for the pain.

Now, looking back at this part, no wonder I had extreme skin blisters, hives, rashes, extreme sweating....this Lidocaine for rectum pain was harming me and no one took me off of it. I finally had my pharmacy tell me this was so wrong to be using 134.00 a month for over one year for pain. I stopped!!!! he seemed to say that I was being harmed.

Suddenly, at my clinic, all of my primary doctors began to do trigger point injections weekly, monthly and for 4 years for my Fibromyalgia comlaint. DX in 1989.

Many NSAIDS for one year, 2003-2004.

In 2003 I had a new denture and a few teeth extracted so that I smiled great when got married April 2003.

By August 2003 I was off the State HMO, had housing city of salem voucher for 5 years at my apartment and was planning to move out and be at my husband's home, but...by September 2003 I was already in some medical exams, new meds and was being normal to a point.

By late 2003 to mid-2004 I was feeling strange about my health. I felt as if I was being sucked dry of any fluids, weird to say, but it felt as if...hard to explain.

I was dizzy, vertigo, some balance problems and like itching, sweating and extreme fatigue. I felt like i was melting. My muscles felt like jello. I had no ability to stay upward on my spine.

I did complain to my dentist and doctors that I was feeling numb on my face and gums by may 2003.

After 2 years, leaving room for a possible lawsuit on the dentist/OS, I filed, had one deposition and my lawyer walked.

I had laughing gas for teeth extractions/numbing shots.

I thought that GAS/SHOTS was to be blamed, maybe the tools they used, or the water and I worked this case to the bitter end, sad to say, that a Lawyer Walked On Me.

By 2004 I did not know what hit me with my health issues..dentists/new meds/new marriage/new doctors involved.

I was in a drug stupor, taking almost 30 drugs from this clinic in 2004.

Prescribed and the samples of Vioxx, Mobic, Celebrex and Bextra.

I had so many Toradol shots to my spine and hips at this clinic and thought they had crippled me.

This doctor humiliated me.

Told me that I was a nut.

I now needed long term counseling with all of the body ailments they all told me. My primary doctor told me many times that NONE OF THE SPECIALIST NEEDED OR WANTED TO SEE ME FOR ANYTHING.

Nothing was hardly affecting me when I got married April 2003. I was a knock out!

The Gastro doctor had me on his 3 drugs also, including that daily Lidocaine up my butt. He did the endoscopy and colonscopy, bloodwork and he said I had Atrophic Mucosa.

He was in direct conflict with my Neurologist who did his own work and he claimed that I was Gluten sensitive, a Celiac now. He gave B12 shots and Folic Acid on top of all the other crap that I was taking.

The Hospital did a spinal tap and may tests.

The pain specialist did his epidurals 2 times.

I have had every NSAID they prescribed me.

I had sleeping pills.

I had anti-depressants.

I had Vicodin to Percacets and then they tried to get me on Methadone. One week on that crap was all.

I notice that Depo-Medrol, Marcaine, Lidocaine was mostly used thru out my life.

The pain specialist above that I used in 2006, also shot me with the epidurals 2 times before 2006, and the O.H.S.U. also shot me with all the above when they DX me with Fibromyalgia 1989.

Then many Toradol and Kenalog shots.

I live with daily diarrhea since 2005-2008.

My legs are always red every day with any walking, sleeping, sitting, balance is off, waddling gait.

My feet pain is as if I walk on glass or rocks....sharp pain now for 4 months.

Arachnoiditis fits me well. I have spoken with the doctor/expert that can test me.

I have been searching since early 2004.

I have no way to know who or what to blame.

I even thought that the MRI's Contrast Agents harmed me starting from the past to now.

I left the clinic that stole my life from me and now have a new doctor at Kaiser Permanente.

I am scared of all doctors now.

I have 4-5 meds right now.

Not one doctor or specialist will DX me. I have a thought below...

I fought the medical community WORLD WIDE back in 2002-2003 with the President Dr. Richard Willner, of Retired Association of Physcians and Surgeons. My two other sisters were in this heated debate.

I was told to expect danger at any time after this online 30 page cruel attack by the doctors on my wrongful death of my mother by her doctors/nursing home/hospital.

I proved this case.

The lawyer in Portland, Or. Judy Snyder told me I did extremely well proving this death was murder...but the Medical Consultant who did the summary of this death was hushed up!!! Later on, after another summary by Medical Consultant, she told me that we would be lucky to get $10,000 for a Nusiance Claim. I tried to get one Lawyer before the statues ran, but no luck. I heard that the Elder Abuse Statues ran for 7 years and to try for that. Oh well, I tried.

Joanie K.

I am so upset just reading these posts! I started on a regimen of 500 mg of Levaquin on Tuesday, January 15, 2008 along with an Advair inhaler for treatment of a bronchial infection. On Thursday I started feeling twinges in my knees when I went up and down steps. By Sunday, I could barely bend my knees so I called the Pharmacist. She suggested it was the Advair so I discontinued using it but still called my MD in the morning. She prescribed massive doses of ibuprofen (800 mg) which in a 32 hour period did NOTHING to relieve the pain. If anything it has gotten worse. I spoke to a friend the same evening who said her husband had severe muscle/joint pain in his hands when he took Levaquin this summer. This morning I called my MD twice in tears (she didn't respond until 3:30 PM.) She still doesn't seem to think it's the Levaquin but told me to take Benadryl (after I told her that this is what my friend's husband's MD told him to do!) I am going in to see her on Thursday morning and I will go armed with these comments from all of you brave people who are suffering from the effects of this awful drug!

Survivors Of Prednisone
Type: Common Interest - Health & Wellness
Description: Many of those with auto-immune diseases such as Crohn's Disease are forced to go on a prescribed steroid known as Prednisone. The effects of Prednisone are terrible. Prednisone creates water retention (puffiness) in your face and torso. It causes severe mood swings. It also causes your hair to fall out. And that is just going on the Prednisone. Once you get off the Prednisone, you then have to deal with the adrenal insufficiency as Prednisone can shut down your adrenal glands.

There seems to be little support for people who have been on Prednisone. They seem to be left alone to deal with the side effects and the confusion and fear that it causes.

This is what this group aims to do:
***
Provide awareness of how Prednisone can and has affected lives.

So if you are feeling down or suffering from crazy mood swings or can't handle looking in the mirror anymore then come and let it all out !

I have been on Prednisone for 27 years for Addison Disease. If you take more prednisone than needed for you system you will get the moon face, weight gain and even the shakes. My immune system is very low due to the medications, my legs cramp and make is very hard to sleep. I have found that after taking prednisone for so long, it will start to deteriate your muscles, blood vessels, bones and teeth. At this point I have no choice but to take this medicaiton as it keeps me alive. By the way, if you are on Prednisone too long your Adrenial glands will stop producing the steriods that your body needs. This medication is very hash. Please advise if any one else has Addison's disease and are taking medication other than prednisone for the illness. I feel for anyone that has to be on this medication.

I have MS and was put on this medication for an episode I was having, severe vertigo. The veritgo would hit while driving on the freeway or at any other time of the day or night; therefore, the doctor felt the best action would be to take massive doses of Prednisone in hopes it would stop the vertigo. With all the side-effects I had from taking this drug it may have been better dealing with the vertigo!

I was NOT informed to check my blood sugars, I am a Type-2 diabetic, but was instructed to eat every 4 hours with each dose I took. I ended up in the emergency room with blood sugars over 600. My vision was effected to the point I didn't need my prescription lenses to see. I had insomnia. Couldn't stop drinking water, nor going to the bathroom (not sure if that was blood suger related, the drug, or both). I was delusional (and not normally so). I had the acid/reflux so bad that it was difficult to swallow food every 4 hours which lead to early tappering off the drug. I developed acne over my face and chest. I ached everywhere and felt like I would die.

The positive experiences I got from my Prednisone was the bond I developed through sharing my side-effects with another person who had also had bad experiences with the drug. I could see the leaves on the trees yards away without my glasses. My sight returned to "normal" about 2 weeks to a month after the treatment ended. The vertigo stopped and the loss of the use in my right hand and arm (MS related) came back 100%. I appreciate the life I have been given and am greatful for my health.

I, too, have suffered side effects from Prednisone. Being severly asthmatic, have been on "bursts"...which consists of taking beginning dosage of 60 milligrams a day for three days, then tapering off.

Have also had massive doses of this blankety blank drug while hospitalized for asthma.

Before the onset of adult asthma, I weighed 105 lbs. Now I weigh 200 and have that "pregnant" look. I have warned all I know not to pay attention to me while I am on the drug...I become argumentative and overly assertive and thank god, I have not become physically agressive.

My feet and ankles swell to twice their normal size as does my fingers, face, etc.

Appetite is completely out of control...eat, but never fell full while under its' influence.

During taper-off times, I have absoulutely no energy for days...even walking to the bathroom is a chore...weak and exhausted.

I now use an steroid inhaler. Supposedly, this does not enter your system, but I question that....how can it not enter your tissues and your bloodstream, if it is entering your lungs? And the same side effects are there, though not as severe, and not as easily apparent. I have gained another 10 lbs, and find I am depressed because of more weight gain and breathing is more difficult because of the extra weight.

I suppose I should be thankful it has saved my life, but the quality of my life due to this drug has been severly affected.

Can you tell I hate the stuff?

We can send a man to the moon, but science can't or won't (for whatever reason) find an effective alternative drug...sigh...

I was prescribed Avelox on December 21, 2005 for an ear/sinus infection that would not go away despite taking other antibiotics. I took the Avelox about 9:30pm that night and 20 minutes after taking the first pill the stomach cramps started and I rushed to the bathroom, while on the toilet I started vomiting in the waste basket, then I felt (the only way to describe it is a burning) in the middle of me body and it seemed to start to spread outward. In a few minutes I was drenched in sweat (my hair was dripping wet) and I started to tremble. I made it out of the bathroom and yelled to my husband that we needed to go to the ER. By this time I was starting to have trouble breathing - my throat didn't close or anything - the feeling was in my chest, felt like my lungs wouldn't expand and I was gasping for breath. Instead of calling the Ambulance my husband drove me to the ER which is less than 10 minutes from the house. When I got to the ER all I was able to say was Antibiotic Allergy and they started giving me shots. I lost consciousness (sp?) and when I woke up some 30 minutes later I was having convulsions. The ER Doctor said I was going to be all right but I was a very lucky girl - couple more minutes and I would have died. The gave me massive doses of epinephrene and steriods to conteract the Avelox. They wanted to hospitalize me but it was 4 days before Xmas so I pleaded with them to let me go home so that Christmas wouldn't be ruined for my 3 small children. Almost was a disasterous Xmas, thanks to Avelox. Later learned that Avelox has a high incidence rate of allergic reactions --- Anaphylatic Shock -- So people beware READ the information carefully before taking any medication.

I have not read these page until this morning. I was looking specifically for advair/singular combination side effects. I became somewhat suspicious of the possible side effects of these medicines some time ago. After reading these postings, I now think I know where the conditions I have experienced come from. I would advise everyone, especially those who have life-threatening asthma or restrictive breathing disease, to see their physicians before stopping medications. As for me, I have weaned myself off of all advair/singular/broncho meds and it has made all the difference. I keep my emergency inhaler with me at all times as I live in the country with outdoor work, dogs, cats and other critters, but to me, the side effects I experience for my particular condition (not as serious as others have) were not worth the dangers (high BP, weight gain, muscle join pain, breathlessness, irritability. And to Trie, your posting could have been mine. I am now taking massive doses of CS (common sense) and E (exercise) and lots and lots of H2O. Good luck to all of you.

My 16 year old son has been on prednisone for 7 years for Hashimoto's Thyroiditis, Asthma, and Idiopathic Angio-Edema (deep tissue swelling/hives) with Chronic Uriticaria (Hives). He started on massive doses but in the last year decreased to 10mg every other day. 3 weeks ago we discovered he has developed scoliosis due to the long term use of prednisone. They tapered him off in 2 weeks. Now 1 week later he is having a type of withdrawl from it... weakness and no energy, nausea and headaches. He is never allowed to take prednisone again, and now the doctors are talking about putting him on cyclosporine. Has anyone experienced this too?

I have cusining's disease. I was on Kenalog for arthritis in nec and shoulders for almost two years. The doctor stopped the shots abruptly and put me on VIIOX till it was taken foo the market. I have been on predisone for a year now and continue to decrease my dose. I have every symptom of Cushing's from Moon face, buffalo back and neck. And weak muscles, joints and so much pain. My wuestion is my teeth. I have lost 3 molars and have 4 more indanger. Can you give me some documented information on steroids and my teeth after prolong use. I need my dentist to receive this info so the insurance company will help with the expense. Any web sites, written documents would be appreciated

Regards,
P.J.

I am 54 and have recently been diagnosed with a lung disorder known as Boop as well as hemolytic anemia both of which require massive doses of steroids. I started out on 100mm for ten days, IV. and went home on 80 two weeks later. I am now onn 50 daily and weaning off 1omm at a time to see how I am doingl. Both illnesses are life threatening if not treated so I really don't have much choice. I may even need chemo for the blood disorder as well.
I have the same miserable side effects you all mentioned. The moon face is like looking in the mirror at a monster I don't recognize. My mood swings are awful, I get so angry at my husband and son as they just don't understand what it feels like. All the aches, the insomnia, the weight, bloat and pains in back and side. I know that I have to be on this for a minimum of 6 months manybe more and I can't stand looking and feeling like this. I already had a weight problem because of meds I am still on from when I had Breast Cancer five years ago and they put weight on as well. (I used to be a size 5 and now I can't even look and see what size I wear. Of course I guess it is better to be alive and fat then dead and thin, but sometimes I don't feel that way. Why can't they find a drug that can work withougt all these other side effects.

I took Levaquin from May 1, 02 until July 19,02 for an infected hip prothesis. I developed severe pain in my fingers, knuckles, hands, shoulders and TMJ joints. The Dr. said it would go away. As of May 9, 03 I still have the problem and am seeing a rheumatologist. He, through blood test said I have ANCA Positive vasculitis which is caused from taking Levaquin. The course of treatment is steroids. I took steroids and the raised havoic with me, and only made matters worse. His next course of action is massive doses of steroids. IV therapy for three days followed by 100, yes 100 days of taking 15 mg prednisone daily. He treated his only other patient with ANCA Positive and it did not work.
I'm currently waiting to get in to Mayo Clinic, Cleveland Clinic or University of Michigan Medical Center.
My question to anyone out here is if there is a class action law suit going against the manufacturer of Levaquin.
jcoleman@shianet.org