Medicine studies symptoms and conditions

I am a 54 year old male who started taking Lipitor about 4 years ago. It seemed OK at first, but over the next several years I began to have increasing amounts of joint pain after exercise. Nor muscle pain, joint pain. And it seemed to be a result of exercise. By the time I stopped it, I was hurting after everything, not just exercise. I felt better within the first two weeks, but it took about 4 months for me to be able to exercise vigorously again. Over the years I seemed to have forgotten how much vitality I used to have. I am a physician, and because of the long lag time until I felt better, I wondered whether improvement might have related to other factors, so after about 5 months I decided to restart Lipitor. It surprised me that after just one dose, I got back all of the joint pain and fatigue when I was at my worst on Lipitor. I was really hurting. Needless to say, I didn't take any more.

Coincidentally, a physician friend of mine who had statin induced polyneuropathy had a similar experience. After his symptoms went away he found that after only one dose the entire polyneuropathy came back.

Stopping and restarting the drug is a way to test the correlation between the drug and the side effect. For such a large spectrum of side effects to recur after only a single dose, it argues that the problems that my friend and I had was due to some sort of immune memory response. I have not seen this in the medical literature.

I am off it now for about 8 months and am able to comfortably play singles tennis and jog - much more energy (and I took 200 mg of CoQ10 a day with the Lipitor).

On lipitor for 1 1/2 years.... starting taking yoga a month ago. Had ache in knee and leg which then went to toe on other leg. Thought it was overstretching from yoga. Pain moved to hips and lower back. All very painful but worst was yet to come. Pain moved to neck and shoulders. Could not move head. Excruciating SOBBING pain. I was in so much pain for weekend. Everyone wanted me to go to emergency room but I wanted to stick it out til Monday.

PS... went on web. Saw this is lipitor side effect. never would have expected that after 1 1/2 yrs on a 10 mg dose.

Went to pain management doctor ... got Soma (muscle relaxant), an oral steroid and Percoset. Relief was almost instant.

Called my cardiologist. He says it is the Lipitor.

No more statins for me.
And back to yoga.