Metformin symptoms and conditions

I have been taking Januvia for the last 2 years. Now, I have lesions on both feet and legs. My feet are now going numb. On 11-9-2009 my Dr. took me off Januvia. Said the lesions were a side effect of Januvia. Also, I can't stay in bed past 3:00 A.M. I am still taking Metformin.

I just started taking this drug three days ago, and I am already having such bad side effects that I don't want to take it anymore. I am only 29, but have a family history of high BP, and went to the doctor last week to find out my bp was 175/90. Since starting the drug, I've been getting dizziness, but last night took the cake. I woke up around 4:30 with horrible nausea. I ran to the bathroom where I fainted while sitting on the toilet lid, wanting nothing more than to vomit. I remember waking up and looking in the mirror, and my face was as white as a sheet, as were my lips. I looked dead, and it scared the hell out of me. As I came to, I suddenly had diarrhea hit me, and once that was over, I felt better. My husband thinks my body is trying to get rid of the drug. In addition to all this, I am having palpitations and feel that my heart is beating too fast. I know that part of this is nerves, because I'm scared of taking this medication, but the fainting and nausea ARE because of the drug. I called my doctor today, and she wants me to come in to get my BP taken again. I am so scared that she won't lower the dose or (better yet) switch me to something else, because my bp always goes up at the doctor's office when I get nervous, every time. Oh, and I also started metformin last week because the doctor tested my blood sugar and it came back 250. Could it be the combination? I don't know. I just know I have only been on this stuff for a few days and already hate it and feel that it's bad for my body! It's very scary.

I have been on Metformin for 6-7 months 500mg 2 x daily, and have puffed up like a balloon with significant weight gain of at least 45lbs., no desire to do anything physical as I have no energy,stomach upset and increased bowel movements, flatulence and absolutely no sex drive. I am going to discuss this with my doctor but before I do in their any other medications other then Glipizide for type 2 diabetes? I keep putting on weight like I am my blood sugar will be way out of control.

I am a 43 yr. young lady and have been diabetic for about 7 years now. I take Metformin, Glipizide, Biata 5, and recently(2 weeks) Januvia.I have been having RAPID heartbeats when I go to bed at night. Also, My chest all the way up to my throat is tight and feels like it is closing up.I have had the worst headache ever, I thought my head was going to explode! I am stopping this medicine. I thought I was going crazy but after reading all these other peoples side effects I am done with it before it gets worse!

I am a 50 yr. old female diagnosed with diabetes 10 months ago. Tried Metformin for a couple of weeks and feet started swelling significantly. Have been on Januvia and Starlix since March '09. Just spent 9 days in the hospital with PNEUMONIA in my right lung only. Drs. are considering the fact that I have a very ENLARGED LIVER (19 cm. avg. is 12 cm) to be the cause of my pneumonia and having 3 liters of fluid removed from right lung cavity as the cause for my pneumonia. Liver function tests show liver is working fine. Anyone else have enlarged liver problems or pneumonia while on Januvia? I'm off it now and dreading what will happen to my sugar level. I also take ENBREL for my psoriatic arthritis and stopped it when my pneumonia developed.

I'm a 65 year old type 2 diabetic with low-functioning thyroid. I was put on lisinopril over a year ago to prevent kidney problems. I have been on 10 mg tablets. Even before I was diagnosed with diabetes I had low blood pressure so that was not a problem.

My main side effects are hair loss, coughing, insomnia and leg cramps, joint pain. I think the lisinopril is pulling nutrients from my body. I told my family doctor about the side effects I had found but he seemed more concerned about the possibility of kidney problems than any of the side effects. I know my hair loss is not age related as both of my parents had full heads of hair when they died and my mother was also a type 2 diabetic.

My blood sugar is under control, tests usually 85-90 twice a day, last A1c was 5.5 which is quite good. I take Byetta and metformin twice a day, levothyroxine, enablex. I recently started taking magnesium as it was besides calcium plus D, a multivitamin all ordered by the doctor. I also take crestor. Feels like all I do is take pills!

My weight is 166 but I'm short, 4' 10", so still heavier than I should be for my height. I try to get exercise but have degenerative arthritis in lower spine. Funny that I developed bursitis in my right hip recently, I just thought the arthritis was spreading. Now I'm not so sure it might not be due to the lisinopril also. I stopped using it yesterday so we'll see how long it takes my body to recover from this drug.

Does anyone have any experience with how long it takes to stop coughing or for the hair to regrow after quitting lisinopril?

I am 56 years old and was diagnosed with type 2 diabetes a year and half ago. It was in the borderline stage but I was experiencing severe symptoms such as: intense hunger, blurred vision, and fainting spells. After a lot of begging, my doctor finally put me on Metformin.

Unfortunately, my diabetes went coo-coo on me last April and I got very sick. My glucose was at 465. I could not drink enough water, could not sleep, bad taste in my mouth, I thought that I was going blind, and I was urinating every 2, 3 minutes. I lost 31 pounds just in that short time. But thank God I started to recover end of June.

The most strange thing happened to my vision though. I had been wearing glasses for the last 20 years and now my vision is crispy clear. I do not wear glasses anymore.

I have depression, digestive problems, very bad constipation. For 2 long weeks, the Metformin could not bring my glucose down from 465, and therefore, my doctor gave me some samples of Januvia. Since I started taking the Januvia I noticed my constipation was getting worse so much that I had to take Mylanta to make me go. My stomach is engulfed with air/gas, and gaining the weight back.

I just picked up a complete new prescription of Januvia yesterday. I started this new prescription yesterday in addition to the Metformin and took one pill this morning. As I am typing this message, I am about to throw up, my stomach is so bloated and heavy I can barely move. I only have between 2 to 3 hours of sleep if I'm lucky.

And my question is, why does this medication is still on the market if it is so bad? Simple, there are many of these doctors on the payrol of these drug companies to push these drugs down their patient's throats. Keep in mind that Januvia is a very expensive drug so these doctors do get big cuts from the drug companies.

Only a few doctors who are still really abiding by the code of ethics by looking after the best interest of patients while for many other doctors it's all about the bottom line.

I'm so glad that discovered this site. Thanks to all of you. From this moment forward, no more Januvia for me.

Hi I have just been given metformin 500 starting of with a quarter of a pill twice daily working up to one pill twice a day (supposed to work up to 2 pills twice daily) thats as far as I've got but will not be going any further in fact have stopped taking them as I'm fed up with feeling as though I'm tired all day no energy can't remember names of close relatives and mood swings and feeling depressed my lips feel swollen and tingling.

I am 33 yrs old. One night I was sleeping and about 12am, I woke up with my heart racing and I was having a squeezing feeling in my chest. I went to the ER and my blood pressure was extremely high. However, when they were running tests on me, they found that I hadn't had a heart attack and I was diabetic. The doctor gave me a stack of prescriptions to start taking. A few months later I went to see a different doctor, one that accepts my discount plan, and he took me off everything but metformin and 5 mg/day lisinopril. Since that night, the beginning of March, I am not the same person. I am keeping my diabetes under control, and my blood glucose is always in normal range. My last A1C test was 5.8. However, I am to the point of paranoia concerning the dead tingling feeling that I have in my feet. It is very on and off. There one minute then gone the next. It's not a feeling of numbness, because I can feel the slightest touch. Now from very little research I have already come to a conclusion that its the lisinopril. THE COUGH is enough to make me depressed and moody on its own, but now I'm thinking that my major mood swings are also coming from this drug. I cry all the time because I am worried that the diabetes is effecting my feet and that is what the doctors tell most people. My doctor said that I haven't been diabetic long enough to worry about neuropathy and that the sensation in my feet could be from a million things. Then almost every website I've looked at so far has hardly anything good to say about Lisinopril. I want to stop taking it, but don't have the money to afford an expensive medicine. what should I do? My blood pressure is usually around 102/68-70

I have been taking Januvia for a year now and my blood sugars have been great. However I came to this site to see if anyone else has experienced extreme hair loss with Januvia. Since being on the drug I have lost more than half my hair. I had lost over 40 pounds a several months back and been very ill with a bowel infection and the Doc thought the hair loss was due to that. Now I think the bowel infection, the weight loss from that and the hair loss were all due to the Januvia. I was on both Metformin and Januvia until about 3 months ago when the Doc took me off of Metformin due to the fact I had lost so much weight and my sugars were so good. I believe now I will go off the Januvia and try just the Metformin! Calling Doc tomorrow!

I was on Januvia for 15 months, along with Metformin and medications for my heart. I have had a skin rash on my face since I started taking Januvia. I did not make the connection between the Januvia and the rash.I stopped taking the Januvia in Feb. 2009 after I was told that the Januvia may have been the cause (or helped to promote) my prostrate cancer. In March 2009 I had my prostrate removed. It has been approx. 2.5 months since I stopped taking the Januvia. My Internist agreed that I needed to stop taking Januvia immediately. I believe that my rash, which I still have, was also because of the Januvia.

Hi, I've been diagnosed PCOS at the beginning of 2007. Since then I'm on Yasmin and Metformin, but I've been reading so many terrible side effects... they say PCOS is a genetic disease and there is no cure for it, so I find it quite frustrating the idea of being under medicaments until menopause... I'm only 28, I would like to have a child or two and I am quite concerned about the risks of cervix and breast cancer. I am living in Italy and they seem to have the same view of doctors in the UK and US about PCOS. I have never had any particular problems before being diagnosed PCOS, no big pain before period, no acne, I just gained weight during university studies in the UK, but I do not think it is the only cause of this illness. I had also a lot of trouble at the beginning and I cannot tell if it was the combination of Yasmin and Metformin: I had nausea, vomiting, diarrhea, etc... It's my 3rd year under this treatment, I think I will do it till the end of 2009, then I might stop. Anyone knows of any alternative method, such as acupuncture, or homeopathy or something natural?
You can contact me for anything at: ******.it, as I'm not often on this website.

I'm a 45 y/o female with PCOS, T2 Diabetes, IR, and a history of infertility. Back before I knew I had PCOS, I was prescribed clomid,and was finally able to get pregnant. Anyway, after my 3 girls were born ( the last 2 were twins), I went on Nuvaring. LOVE It. I have none of the symptoms anyone else here describes. It keeps me regular, and helps me avoid perimenopause hot flashes and sweats. Once I tried experimenting with going off of the nuvaring (so that I could use supplemental progesterone cream), and I gained weight!! Like, 18 POUNDS! My periods stopped and I was a mess. My endo had me go back on the nuvaring, and I resumed normal periods, and life. But now, I am being asked to give it up again, because it was noted during a recent colposcopy (exam with a magnifying scope as part of a follow up to an abnormal pap), that I have vaginal inflammation. I was told to go off the nuvaring. Well, I didn't even know I had vaginal inflammation. Now I'm off the ring, and .... guess what? My weight is going UP again. Has anyone else experienced weight GAIN with DISCONTINUATION of their NuvaRing? It was explained to me that since I have PCOS, the nuvaring might have helped to keep my weight down as it was suppressing my excess testosterone. GADS! What to do?

Not sure but didn't have a problem with sugar until a month after starting Lipitor 80mg. Leg muscles feel like they are going to cramp when I move quickly and I now have much fatigue both muscles and general. AND, I now have to start Metformin for diabetes. No history of diabetes in my family and I am not much overweight and get loads of exercise. I am wondering if the Lipitor could have contributed to the diabetes?

52, BP 150's/100. Taking Metformin twice a day for Type II diabetes. Was prescribed Lisinopril 20mg once a day about 3 weeks ago. After about a week and a half developed constipation, plus a neck ache on the right side - like a muscle strain. ****** lists diarrhea as a side effect - I had to hunt pretty far to find constipation as a possible problem.

Wow, after reading everyone's side effects I don't feel so alone. I've been taking Metformin HCL 1000 mg/day for a few weeks now for PCOS. First it was the severe diarrhea, which has sort of subsided. However, my other symptoms have been getting worse. Such as: extreme fatigue for no reason, weird sweating like on my palms and chest, and severe thirst/frequent urination. I wake up at least 3 times a night to pee, but then I'm so incredibly thirsty I could drink a gallon of juice or water, but then of course I have to pee again. It's a never-ending cycle and I just want to know, do these symptoms go away after awhile? If not, I really don't want to take this anymore. I'm also bipolar and it's been affecting my moods making me very irritable and depressed.

I'm sorry for everyone's troubles with this med. First of all, my blood sugar has been HIGHER than on regular metformin. I'm taking Janumet which is Januvia combined with metformin- dosage: 50/1000 twice a day. I have noticed a FAST heartbeat, irritability / sadness, higher levels in BS. After reading these posts, I AM GOING OFF JANUMET. Most noticeable side effect is the increased heart rate- it feels like my heart is going to beat out of my chest. Scary.

In Feb 2005 I was prescribed biaxin for an ear infection. It was a 14 day supply. I started to take it and with in 24 hrs I felt worst than I did before I went to the dr.
Over the next 14 days I called the Dr. 4 times and each time I was told that if I just take the biaxin I will get better. I did as I was told.
In 30 days I lost 31 pounds from vomiting. Over 60 days I lost 51 pounds. My Dr. finally did blood work and my triglycerides were at 7700. No that is not a miss print. My sugar went to 395. My blood pressure was off the scale.
My Dr. got the results of my blood test and told me I was a diabetic and put me on Metformin and set an appointment for 30 days later. This was the same day I was told my triglycerides were 7700. I was not hospitalized. I was not even to be seen again for 30 days.
I now know what that meant. I was within minutes of dying and my Dr. tried to hide it. He could not have cared wheither I died or got better as long as no one else found out what happened.
Now, after 3 yrs of living a life similar to what I think hell would be like and after seeing specialist and different Dr. they tell me I have pancreas damage and I will be on prescriptions for the rest of my life.
The Dr.'s know what Biaxin does to your body. They don't care! I was ignored for 2 weeks when I called them. Now I will pay for the rest of My life. THANK YOU FAMILY PRACTICE.

Side effects seem to be different with two different brands of Lisinopril.

First maker is International Labs Inc. seems to give me the heavy chest along with more sluggish feeling. Which results in some Ed problems as well. Terrible gas.

Where as I have some Lisinopril from Mylan Pharmaceuticals Inc. which seems to be better.

I was told by someone that the makers may use different fillers to make the pills which I could be reacting too ?

Has anyone else found this to be true, Plus what brands does everyone else get ?

Either way I have been on this Lisinopril for 5 weeks now not liking it much but did get past the terrible couch scratchy throat feel by drinking some milk first to coat my throat, someone told me and it did work.

Waiting to see what troubles show up next with taking this long term. Not sure I can afford the blood work it will require when they soaked me 625 plus 222 dollars for two visits to get this 4 dollar pill.

Maybe they just prescribe this to lower our pressure for when the bills show up for us Unlucky Unemployed people without Health Insurance !!

I've been taking Januvia for about 2 months and have experienced sever constipation. I don’t seem to have an urge to have a BM. I have increased my fiber and water intake with no success. I’m also taking Metformin, so I was used to having diarrhea. Since taking the Januvia, I need to take meds to have a BM. I’m also experiencing numbness down the outside of my thighs. I have trouble sleeping throughout the night and I’m very anxious. I don’t know if my problem in the Januvia, but I do know that I did not have these problems until I started taking the Januvia. I’m planning to stop taking the drug for a few days and see how I feel.

I am a twenty-nine-year-old man who was recently diagnosed with Type 2 diabetes. I also have had a diagnosis of hypertension for nearly seven years, but have not been on any medications for the condition in as long. I was prescribed Metformin for the diabetes; Pravastatin to raise my HDL; and Lisinopril for the hypertension. I took myself off the statin after I read all the nasty things it can do to your body long-term a month ago. Since then I have been feeling crappy nearly every day; finding it hard to sleep, and when I do, get restful sleep; and I am overcome with attacks of weakness and fatigue while I am out and about each day. At first, I attributed these symptoms to weakness from the diabetes or withdrawal from the statin, but after reading the posts here I am beginning to wonder if its the Lisinopril instead. I take five mgs a day, and it has helped level out the blood pressure, but I experience palpitations and a higher systolic pressure sometimes. Especially when I don't take the drug at the same time. Any thoughts?

I was given a shot in I think January of 2008, not knowing exactly what it was, because I had a fever and the doctor said it would jump start my recovery. At first there seemed to be no problem with the injection site and I felt great just days after.

A couple of months later, when I was working out and losing weight and keeping a very close eye on my body because of it. Suddenly, I noticed that I had a deep indentation and discoloration on the left side of my lower back - right where they gave me the shot. It seemed like it appeared over night. It got deeper, and darker as time passed.. I was scared to press my finger in it because when I did, it just kept going in..as if there was no fat OR muscle in that spot.. I was FREAKED out. I'm a model so this fact that there was a bottomless whole in my lower back was devastating. I also feared that there may be something life threatening going on. I mean, a chunk of you just doesn't disappear overnight..Unless someone stole your kidney, but, I didn't wake up in a bath tub full of ice.

I typed in "Injection that causes Indentation in the lower back" and I found this board. Everyone here suffered the same exact symptoms from this shot and worse. I was certain that it had to be Kenalog. It seemed to cause death of all tissue at the injection site, depression, lethargy, moodiness, insomnia, pain and all sorts of other symptoms after this shot. I started to suffer from all of them soon after the shot and I didn't really know why or where it came from. I was in so much pain and was so tired.. I stopped doing everything I loved and I could barely sleep because of the pain.

I don't know what to do about this. I'm extremely broke and I don't have health insurance(and they wouldn't fix anything considered to them as "cosmetic" anyways).. My parents are in no position to help me anymore and I could never afford an attorney to try to claim against this.

How can I go about fixing this with no money? Is there any way to fix this to begin with?

Any advice, insight or experiences would be GREATLY appreciated!

hives, redness and severe itching on hands, fingers, and forearms. Pain in shoulder which I can only describe as feeling like I slept on it wrong. Nerve-like pain in lower legs/shins (not muscular) which comes and goes and is not associated with movement or exercise - sort of like if you had a back problem, but intermittent.

My doctor decided to switch my medication from Actos (15mg. daily) to Januvia (50 mg. daily) to try to get better blood sugar levels (120-130 mornings). Took Januvia for about three weeks. After two weeks, started experiencing sleep disturbance (waking every few hours), chest pain, digestive distress (could barely eat toast and eggs), anxiety, and flu-like symptoms (muscle aches, headache) which I thought was my fibromyalgia flaring. Went online yesterday and found this website which described many of my symptoms. Never associated them with Januvia. Did not take medication yesterday and feel 95% better today. I will not take this medication again. Also, Januvia did not lower my blood sugars. In fact, morning readings were higher (140-165).

I AM PREDIABETIC...TYPE 2 - FASTING GLUCOSE OF 112-120 OVER THE LAST 10 YEARS. I HAVE WORKED NIGHTS FOR THE LAST 35 YEARS SO MY EATING HABITS ARE OUT OF WACK. MY HEALTH CARE PROVIDED PUT ME ON METFORMIN 850 MG 2X DAILY AS A PRECAUTION TO KEEP MY GLUCOSE LEVELS THE SAME OR LOWER. I DO NOT HAVE ANY SIDE EFFECTS PER SAY, BUT IS THIS MED SAFE FOR ME??? HAVE NOT FELT ANY SIDE EFFECTS BUT WOULD LIKE TO KNOW, ARE THEIR ALTERNATIVES FOR ME??
THANKS