Mid 50s symptoms and conditions

I'am 45 year old female and I have been on simvastatin 40mg for at least 6 months. Here in the past 3 weeks I have had very weak legs and arms,they felt like they were wet noodles. I also was getting these week spells where it felt like I couldn't lift my arms or legs cause they was so weak.I had pain in my ear and big bad headaches that wouldn't leave. My heart feels like it skips a beat and I get very bad anxiety attacks. I have been to the ER several times and they can not find anything wrong. I even got very dizzy. The ER doctor told me that the dizziness and headaches was from a inter ear disturbance,well I think the inter ear disturbance might have come from the simvastatin after running across this web site. I'm going off the simvastatin tomorrow! Oh yeah and forgot to mention the weight gain and the tiredness and how I feel like a couch zombie. I think I'll stick to my salmon oil.

No side effects yet - coz I haven't taken it!!! I recently had my blood work done, it had been 2 years slightly elevated cholesterol so, in those 2 years leading up to latest bloodwork, I've eaten oatmeal every morning, taken Flax/Omega 3, B-complex, olive oil for all cooking, I have a glider, 20mins. 5 days wk. but had to watch myself, lost too much weight, I'm only 105lbs now, etc. etc....so, shock and horror my latest results: 232 Total Chol. 157LDL 57HDL-good number really, and best thing, 91 triglycerides, glucose 87 - so I guess some of the above improved some numbers. Dr. suggested a doppler/carotid.....a note received yesterday "some build up" and enclosed prescript. for 40mg. of this poison which seems kind of a high dose to me? So, is he not telling me the extent of "some build up?" what's "some"....I need to find that out first - but I really don't think I'm gonna be taking this stuff - there is so much info out there debunking this cholesterol thing....I'm 58, would there be natural build up in arteries, I mean your plumbing pipes don't stay pristine forever - there's bound to be build up, surely? Or am I kidding myself. Any suggestions out there, people!????

I was “poisoned” by Levaquin -- resulting in acute tendinitis in both Achilles tendons.

Background:
I am a healthy, athletic male in his mid-50s who has never had an Achilles tendon problem. In early July 2008, my doctor (general practitioner) prescribed Levaquin for an infection. I took the medication for 14 days, as prescribed.
Sudden onset of acute tendinitis in my Achilles tendons occurred near the end of the medication period. The tendinitis occurred in both Achilles tendons simultaneously. Nothing related to my lifestyle would have caused the tendinitis.

Symptoms:
Symptoms included the following at one time or another:
1. aching
2. sharp pain
3. feeling of heat/burning
4. tightness
5. pins and needles in small areas (micro tears?)
6. weakness at rear/base of each heal.
7. When I woke-up each morning my tendons and the back of my heal pads felt sore, weak and tight.
At the height of the problems, I had extreme difficultly walking and negotiating stairs, and I thought there was a risk that my tendons would detach from my heal bone.

Doctors’ Advice:

My general practitioner’s and my podiatrist’s advice was to: (a) not run, cycle, hike or otherwise exercise my legs in any manner other than easy walking and swimming, (b) gently stretch, (c) take ibuprofen, (d) ice regularly, and (e) use heal lift shoe inserts made by my podiatrist. Their advice was based on the view that the damage that was done is more like damage cause by an injury than damage caused by an insidious drug. My readings on the subject indicate that little is known about the mechanisms behind this fluoroquinolone-specific toxicity. It is believed that the tendon’s collagen fibers become disorganized and infiltrated with small blood vessels -- resulting in weakness. And there are no specific treatment plans for this problem.

After 2 months of living with these symptoms, I decided to change course.

My Approach to Healing:

Because I never believed my pain was the result of inflammation, I stopped icing and taking ibuprofen. Because stretching seemed to further weaken the tendon and set me back, I stopped stretching. Because I believe that the body heals itself best when used, I started cycling at an easy pace. I then worked-my-way-up to cycling more aggressively, and to walking in the neighborhood. That’s where I am today. Two days ago I had my first day without discomfort in 3 months. Yet, I have a long way to go. I am not yet hiking or running. It’s a slow healing process with occasional setbacks when I push my tendons a bit harder than I should, Given the progress I have made, I am hopeful for a full or nearly-full recovery in another few months.

Other things I have done in the past month:

1. Taken L-Lysine (1000mg daily), which is believed to aid collagen formation.

2. Taken Magnesium (250mg daily), which some believe may help leech the fluoroquinolone molecules from the tissues because of the affinity of these antibiotics for minerals.

3. Taken Fish oil pills (3000mg daily), which improves circulation

4. Used a heating pad, which improves circulation

5. Started regular Acupuncture (first time for me), which improves circulation

What you can do:

1, Be easy on your tendons until you get a handle on the problem. Don’t over-use tendons when they are in a weakened state.

2. “Listen” to your body and take steps you think best to help the healing process.

3. Tell your friends to beware of potential side effects from fluoroquinolones.

4. File a MedWatch report with the FDA at fda.gov.

5. Share your findings/advice on this forum.

Good Luck

My son, who is 8, has just been prescribed Lexapro. He's only been on it for 2 weeks and is taking only 5mgs. He was diagnosed with depression. The first four days were wonderful. I had my sweet, loving boy back. Since then, a lot of "crap" we have been dealing with is back, but at least the sadness/aggression/temper have not been as bad as before. He is having horrible stomach pains, but could be caused by allergy drainage or possible intestinal problems that have yet to be diagnosed. Anybody out there with a child going through the same thing?

My son was also taking Singular for 8 months last fall and that was a NIGHTMARE! Don't ever allow your child to be prescribed this medicine, especially if they already have behavior issues.

Hi! I am a 36 year old female and have been on this HORRIBLE HORRIBLE drug (prednisone) for 2 1/2 years now..... Hopkins doctors still arent sure exactly what i have. My immune system is attacking my liver so to speak. My body is basically looking at my liver like it doesnt belong and is attacking it with large multiple lesions that is eating it away... the good thing is that it hasnt interupted the functioning of it yet but is leaving horrible scar tissue. I have been in and out of the hospital 13 times, have had just about every test imangable, 12 liver biopsies and they STILL have NO clue! They are leaning towards Church Straus desease and Wegners but the weird thing is i have half symptoms of both. The first year they had me on 80 mgs of prednisone a day which had seemed to put me in remission for about 4 months and then they came back even worse so i was put back on the prednisone, 80 mgs a day AGAIN along with 100 cc's of Methotrexate, another not so nice drug... i had EVERY SINGLE BAD SIDE EFFECT OF BOTH DRUGS!! This second time around was ALOT WORSE for some reason!!! My body DID NOT LIKE IT!! Nausea, hair loss, moon face, gained 40 pounds (and i was in great shape, worked out, i am 5'4 and was 110 pds!), EVERYTHING was swollen, legs, ankles, arms, neck, face, had the camel hump, fingers and especially my belly!!! UGH!!! Have bone, muscle, and SEVERE joint pain! Kaliedescope vision, dry eyes and then had mucus discharge (kindof like pinkeye), headaches, intestinal problems.... VERY CONSTIPATED and then the opposite!!! I literally felt as if i had turned into a man in my behind!!! Sorry to be so gross but thats how bad it was!!! Jaw problems, teeth and gums as well, skin sensitivity and have little bumps all over my skin (kindof like tiny little moles), itchy, broke out with acne and pretty much NEVER had more than 1 pimple a month, had facial hair (VERY DISGUSTING!!!! HAD IT WAXED EVERY WEEK!!!!) and then on top of all of that the swelling of my liver not to mention the PAIN! I was recently in the hospital again with 12 new lesions, pneumonia, and 104 fever. My doctors said the Methotrexate was the cause and i was having a bad reaction to it so they now have me on 100mgs per day of Azathiroprine. I am now finally down to a maintenance dose of 5 mgs of prednisone cause my body was starting to reject that as well. I thank god that i am now down to that dose!!!! It as only been 2 wks and the withdrawl symptoms are horrible worse then they were but i know what is to come =) loosing all this fluid and all of the HORRIBLE side effects i listed above. I will have to be on the maintenance dose of 5mgs the rest of my life and can live with that cause when my body gets back to somewhat normal i wont even notice that im on this CRAP!! I will be on the high dose of Azathiroprine for a few years and then on a maintenance dose of that as well for the rest of my life to keep whatever this is that i have under control.... the scary thing is is that they arent even sure that all of these meds will even work...... im a guinea pig..... The only thing that i am on out of all 25 pills/meds that i take everyday that works is my pain meds. Oh and i also forgot to mention that i had to be put on some "HEAD CASE" medication (thats what i call it =) ) for depression. Its a low dose but it does seem to help... I am terrified of what the future holds but continue to be strong and have an amazing support team... my fiance and family =) I dont even want to think about how i would be without them. I go back on the 25th of this month for my MRI so please who ever reads this keep me in your prayers as for all of you are in mine. I feel for each and everyone of you that has to endure this horrible drug everyday and i hope that everything works out you. =)

Sue =)