Muscle problems symptoms and conditions

I began taking Levaquin for a kidney infection. After the first pill (500mg) I had insomnia, joint pain and a little under the weather. I thought maybe it was a combination of the pill and still having the kidney infection. I figured the infection wasn't gone because the first med, Sulfameth/trimethoprim 800/160 I had a reaction too also. That was prescribed for 10day when I only was 4days into it with that pill. So I went from Friday to Monday without any medications. I felt that the kidney infection was still there because I was still hurting, not as bad as when I went to ER but knew it wasn't gone. So Monday night I started taking the Levaquin. Felt bad after the first pill but after taking the 2nd pill I became very weak, had ringing in my ears, eyes started to swell,had sweats nausea, stomach hurt and became very bloated, neck pain so bad I could hardly turn my neck. Pain running down into my shoulder blades, jaw pain, sore throat, nausea, felt like someone was squeezing muscle in left arm and squeezing muscle on left side of neck Started to have some muscle pain in right calf. Call Dr. on call and he said STOP taking the medicine, take some Benadryl and if gets worse go to the ER. Well, I took some Benadryl which made it seem a little better, but this is the day after and my muscles by my shoulder blades are so sore and have a burning sensation. I still feel somewhat weak but not as bad as last night. Seems I tired out real quick. This medicine made me feel like I was on the way out. I was prescribed it for 7 days and only took it for 2. Now I am very hesitant about taking anything as I have had reactions now to 2 different meds. Still don't know if kidney infection is gone or not. Does anyone know of any natural ways to rid yourself of kidney infection? I would appreciate any advice anyone has. All I know this has been 2weeks of @@@@ since I was diagnosed with this kidney infection.

I have to comment..... look at how many entries there are showing side effects.. so many people have the same symptoms. does this not open the eyes of others to accept that it can be a real problem to some people, admittedly not all, but it obviously doesn't agree with all of us. I could not believe my ears the other week when the local GP said that it's rare there are side effects, then 4 hours later a DR. in a hospital emergency department stated that statin drugs are very common for muscle problems, in particular one named brand (need I say more??) Couldn't wipe the smile off my face after hearing someone finally admitting it..
Come on professional people, start listening and accepting that people do know their own bodies and can see and feel so many vast changes in their day to day activities. Maybe guide people to a better understanding of diet and lifestyle before dishing out meds. so quickly. Give us some credit......some of us exercise regularly, we want to live healthy too and all this has done is put a stop to that luxury.
I have to add, I posted earlier this month, I AM getting much better each day, clearer thinking, vast improvement in mobility, so please stay positive and take care of yourselves, obviously we all need a little patience, hard to do after some long term suffering i know, we want overnight fixes just to feel normal again.. :-)

After a sphenoidetomy, it showed that I had a staph and fungal infection that wasn't clearing up so the doctor prescribed 10 days of 500 mg. of levaquin. just 2 days taking it, I developed pains in different areas of my body. I couldn't use my arms as both shoulders were affected. Then, I had edema in my lower legs and ankles. This was 5 months ago and I still have pains all over. They move around. This medicine is deadly for the body and the head. I blacked out while driving and I am sure levaquin caused it. Also, if you are having muscle problems with this drug, ask your doctor to do blood tests to see if your muscles have been damaged. I have had creatine kinase blood test 3 times and they all showed abnormally high levels. I have read that time is the only healer. Good luck!

My dr. put me on Lipitor. I took it for 4 months. At the 4 month mark, I was SO depressed, I couldn't function. Crying constantly, no concentration..almost like I was in a trance most of the time. I had problems finding the correct words to use, was paranoid about everything and everyone. I actually thought I must be in the early stages of Alzheimer. Honestly..I didn't know what was wrong with me. I had an actual "pain" in my heart and pins and needles feelings in my fingers and hand on the right side. My forearm became terribly "achy". I went back to the dr. and she said.."oh, I think you're depressed!" Gave me a prescription for celexa (anti-depressant, and sent me on my way. I went home..decided that I WAS NOT going to take an anti-depressant and began to do a little research on the lipitor. Amazingly..I couldn't believe the info that I found with people who had the same symptoms as me! I stopped taking it immediately and within 2 days..my depression and paranoia went away. However I am left with such weakness and pain in my rt. forearm and bicep as well as both shoulders. I went back to the dr. and explained what I had done (guess I shouldn't have mentioned about what i had read on the internet) Because she wouldn't believe that the lipitor would cause that and also said that I had been off of it long enough now(4 months at that point), that any pain that i was experiencing would be all gone! She wouldn't believe me and made me feel like I was crazy!! So..now not sure what to do. Will the pain go away, I wonder? Is there a way to "detoxify" one's self to rid us of all the bad stuff or is the muscle damage permanent and does it keep on going and just keep destroying the muscles, even though we've stopped taking the stupid stuff?? I wish someone could come up with an answer, because I don't know who to go to ask. I can't believe how weak my arms have become since taking it. Will it ever improve I wonder?

This is an update. I have experienced "some" problems trying to get Doctors to believe that my muscle problems are Lipitor related. I was sent this by a nurse. It is not the full page.

"2005 Mosby's Nursing Drug Reference (pg.155)

atorvastatin
Lipitor

Uses: As an adjunct in primary hypercholesterolemia

Interactiions:
*Risk of possible rhabdomyolysis; azole antifungaals,
cycloSPORINE, erythromycin, niacin, gemfibrozil, clofibrate".

Guess what? I have been using an azole antifungal intermittently for the entire time I was on Lipitor. It is not a medication I "take". It is used topically for a fungal nail which refuses to clear up. You may have been using it for athletes foot.
Now one pharmacist says a topical application cannot cause this interaction and another pharmacist says it is almost certain that the azole antifungal gets into the blood stream and will interact with the Lipitor. I have to laugh.
Next week I start Physical Therapy on my left elbow.

I am wondering if the plantar foot pain that my husband is suffering for 6 months could be from lipitor that he is taking for several years now. Has anyone have this problem?

Yes, I have been taking Vytorin 10/40 for about 10 months, and it did reduce my cholesterol and triglycerides to 'normal', however, I slowly developed (initially) some 3 months back, problems in my left solder, diagnosed eventually as 'rotator cuff' ligament damage, however, it came on slowly and progressively worsened. I had not done anything strenuous to develop such a condition. It became so bad that I was basically redd to using my right arm. On top of this, the muscles in my lower arms became sore and felt strained even lifting a glass of water was painful. My Doctor was informed of increasing on-going muscle problems, did an emzine muscle test, which turned out to be 'clear'. And I also lost my sexual drive gradually.
I went off taking Vytorin a week ago on my own gut feeling, and my arm muscles and left shoulder have improved. I am also hoping no permanent damage. I am moving to a much higher exercise regime to 'burn' cholesterol and reduce triglycerides, and in the mean time look for 'natural' solutions as well.
I am not impressed with the medical responses I got, along with miss-diagnosed muscle / tendon supposed 'rotator cuff' serious problem that developed in my left shoulder, which I suspect may never be the same functionally. I recommend looking at other alternatives and natural remedies, this is my course of action. MM

I have been taking Simvastatin 20 mg. for about two and 1/2 months now. It really lowered my Cholesterol but I have been extremely fatigued and now I am getting really dizzy when standing up and having some nausea.

I started using lipitor from my doctor, it lowered my cholesterol all around but I started to have lower back pains. At first I thought it might be prostate cancer, but after having to MRI's done they found no cancer, thank god. But I went to an orthopedic surgeon to see what the problem was. He looked at the mri's and saw lower dics hitting my nerve endings. He also thought that it might be muscle problems so he gave me 3 epidurals and that helped for a while took away about 50% of my pain, but I still have the pain, It is hard for me to get comfortable when I sit or even when I am sleeping. I don't want to think that it is the lipitor that is doing it to me but after talking with others I feel it is time to talk to my doctor about it. My doctor said that lipitor is the safest one that will do very little harm to my liver. I am not a doctor so I would not know.. My cholesterol level was 246 at one time now it is 175. I am now facing possible spine fusion to help correct my disc problem. But will also ask doctor to prescribe something else.

Alan

I am a 54 year old, very active female. Had a UTI and was given 750 Levaquin. I have taken 10 days worth and began having a sore swollen ankle, followed by right knee pain, followed by shoulder and arm pain. I have never experienced muscle pain to this degree before. I am scheduled for a doctor appt in 3 days. I started trying to imagine what could be causing this. I took a shot and looked up Levaqin side effects this morning, after another night of no sleep and severe shoulder pain. Well guess what, from everything I just read I think I found the source. The problem now is how do I get my life back???? The one thing I am sure of is it's time to stop taking the poison!!!

I do think the drug maker should put more emphasize on the side effect! I do believe maybe 98% people who take Lipitor without side effect that is why lots of doctors just ignored this fact. I was on Lipitor for two month with daily dose 10mg. Right after one month, I started neck pain with no reason and lasted a month didn't improve at all. Luckily, I thought about the possible Lipitor side effect so that I stopped to take it. Amazingly, just one day without Lipitor, my neck pain almost went away! I tried on/off Lipitor couple times again, and the results were consistent. But, when I revisited the doctor who prescribed Lipitor for me, he just don't believe this fact! He don't believe I had Lipitor side effect at all and prescribed me some pain killer, and asked to continue on Lipitor!
Thanks to the internet technology! I found this website and knowing so many people do have Lipitor side effect! Because this experience, I realized my mother complained back pain for more than a month with no reason, and she was also on Lipitor. I called her, and just two days after stop taking Lipitor, her back pain gone, she can walk again!
Initially, I angry about the doctor! Why he don't follow drug maker directions about the side effect! Then, I realized that in fact the doctor may never encountered Lipitor side effect either patients don't know it is the side effect or most of patients who don't have the side effect at all! I could argue that a doctor is a high trained professional, who should play cautions! Second thought doctors are human too, once they used to the impression Lipitor has no side effect, they may easily miss the warning sign, even ignored the clear fact like my doctor did!
In my view, both doctors and the drug maker responsible for the people suffering Lipitor side effect, but of cause, the law sue against the drug maker is more effective for lawyers!

Can Statins Cause Chronic Low-Grade Myopathy?
Statins (hydroxymethyl glutaryl coenzyme A reductase
inhibitors) are highly effective drugs for reducing serum
cholesterol and low-density lipoprotein cholesterol levels.
Clinical trials have shown that they also reduce risk for
coronary heart disease events, coronary procedures, and
stroke by about one third (1). Millions of people in the
United States and worldwide are being treated with statins.
In clinical trials and in clinical practice, statins have proved
to be remarkably safe.
The one notable side effect of statin therapy is myopathy.
A small fraction of patients who are treated with
statins will develop severe myopathy (2). In the worst cases,
severe myoglobinuria, acute renal failure, and even death
can occur. The incidence of severe myopathy is low, perhaps
1 in 1000 patients (2). Predisposing factors for severe
myopathy appear to include advanced age, relatively low
body weight, female sex, certain medications, use of multiple
medications, multisystem disease, and acute illnesses
or major surgery (3). If statins were avoided or used in low
doses in these circumstances, it is likely that the incidence
of severe myopathy could be greatly reduced.
Less severe forms of myopathy undoubtedly occur. In
some patients, fatigue and muscle pain and weakness develop
with moderately high serum creatine kinase levels
but not acute renal failure. In these cases, the myopathy
resolves when statin therapy is discontinued.
Still more patients report various muscle symptoms—
fatigue, pain, and muscle weakness—but have normal creatine
kinase levels. These symptoms probably are unrelated
to statin therapy in many patients. In middle-aged and
older people, muscle, joint, and tendon symptoms are very
common. Naturally, if a patient takes a medication that is
believed to produce muscle problems, symptoms are often
attributed to the medication. On the other hand, the major
controlled clinical trials have not detected a higher prevalence
of muscle symptoms during statin therapy versus placebo
(1). This failure of detection has generally led clinical
trialists to conclude that statin-associated myopathy with
normal creatine kinase levels essentially does not exist or
that, if it does exist, it cannot be detected above the “background
noise” of muscle symptoms in the general clinicaltrial
population.
Many physicians in clinical practice nonetheless believe
that they can identify a subset of statin-treated patients
who have a unique set of statin-related muscle symptoms.
Some patients clearly relate the onset of muscle
symptoms to initiation of statin therapy. These symptoms
may abate after discontinuation of therapy, only to reappear
when statin therapy is restarted. The number of such
patients is not large, and thus it may have been impossible
to identify them in large clinical trials.
In this issue, Phillips and colleagues (4) report on a set
of studies in four patients who had muscle symptoms during
statin therapy that resolved during placebo use. Quantitatively
measured muscle weakness also resolved during
placebo use. Muscle biopsies were performed in three patients
during statin therapy and then during placebo use.
Several pathologic changes were seen on biopsy specimens
obtained during statin therapy: increased lipid content of
mitochondria, fibers that did not stain for cytochrome oxidase
activity, and ragged red fibers. The authors suggest
that these patients had statin-associated myopathy with
normal serum creatine kinase levels.
Despite the study’s small size, we cannot dismiss these
observations as random variation in muscle structure.
However, these highly suggestive results are clearly preliminary.
The number of patients was small, and all appropriate
controls were not used. Nonetheless, this study is novel
because it used quantitative measures of muscle strength
and muscle biopsy to address the question of myopathy
with normal creatine kinase levels during statin therapy.
To be confirmed, the current data would have to be
extended to many more patients in whom muscle symptoms
are closely correlated with statin use. Reproducibility
of symptoms during therapy and symptom resolution after
discontinuation of statin therapy would be necessary. A
definitive study would have to be carefully designed and
executed. It would need to be double-blinded and placebocontrolled
and include sufficient numbers of patients to
provide a valid statistical comparison. In addition, investigators
would have to carefully consider the appropriate
selection of patients. The development of a registry of candidate
patients at multiple sites could facilitate a multicenter
study.
Is a carefully controlled, sizable study of this type
worth the investment of time and effort? To date, no evidence
indicates that prolonged statin therapy leads to permanent
muscle damage or progressive myopathy in patients
with normal creatine kinase levels. Controlled
clinical trials attest to the general safety of statins, and
symptomatic side effects appear to be limited to a relatively
small proportion of treated patients. In addition, no therapy
prevents or treats statin-induced myopathy, short of
withholding the drug. On the other hand, statins are being
prescribed to millions of people, and are usually continued
throughout the patient’s lifetime. It is certain that statins
cause myopathy in some patients. For these reasons, a valid
argument can be made for a more extensive study of lowgrade
myopathy in patients treated with statins.
In the meantime, physicians should recognize the great
benefit of statin therapy in high-risk patients and their
documented safety for most patients. For high-risk persons,
the proven efficacy for preventing cardiovascular disease
outweighs the unlikely possibility of permanent muscle
damage. Phillips and colleagues’ preliminary results
certainly do not provide adequate information on the spec-
Editorial
www.annals.org 1 October 2002 Annals of Internal Medicine Volume 137 • Number 7 617
trum, scope, or prognosis of myopathy with normal creatine
kinase levels during statin therapy. For these reasons,
prescription of statins for eligible patients should continue
despite the current results. Moreover, before discontinuing
therapy, physicians should carefully evaluate any patient
receiving statins who reports muscle symptoms. In most
cases, the symptoms will be found not to be consistent
with chronic myopathy, and often they will not be related
temporally to statin treatment. High-risk patients in particular
should not be deprived of major cardiovascular risk
reduction just because they display symptoms not clearly
documented to be closely related to statin therapy.
Despite these comments, the actions of statin on muscle
metabolism and structure deserve further investigation
to clarify the confusing area of low-grade myopathy apparently
associated with statin use in a few patients.
Scott M. Grundy, MD, PhD
University of Texas Southwestern Medical Center at Dallas
Dallas, TX 75390-9052
Current Author Address: Scott M. Grundy, MD, PhD, Center for
Human Nutrition and the Departments of Clinical Nutrition and Internal
Medicine, University of Texas Southwestern Medical Center at Dallas,
5323 Harry Hines Boulevard, Y3.206, Dallas, TX 75390-9052.
Potential Financial Conflicts of Interest: Honoraria (from Merck &
Co.; Pfizer, Inc.; Bristol-Myers Squibb; and Bayer); Grants (from Merck
& Co. and Pfizer, Inc.)
Ann Intern Med. 2002;137:617-618.
References
1. Executive Summary of The Third Report of The National Cholesterol Education
Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment
of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA. 2001;
285:2486-97.
2. Staffa JA, Chang J, Green L. Cerivastatin and reports of fatal rhabdomyolysis
. N Engl J Med. 2002;346:539-40.
3. Pasternak RC, Smith SC, Bairey-Merz CN, Grundy SM, Cleeman JI, Lenfant
C. ACC/AHA/NHLBI clinical advisory on the use and safety of statins (1)
(2). J Am Coll Cardiol. 2002;40:567-72.
4. Phillips PS, Haas RH, Bannykh S, Hathaway S, Gray NL, Kimura BJ, et al.
Statin-associated myopathy with normal creatine kinase levels. The Scripps Mercy
Clinical Research Center. Ann Intern Med. 2002;137:581-5.
© 2002 American College of Physicians–American Society of Internal
Medicine
Editorial Statins and Low-Grade Myopathy
618 1 October 2002 Annals of Internal Medicine Volume 137 • Number 7 www.annals.org

I also have been having muscle problems in my legs. My leg muscles have
become weak, and I have difficulty walking up steps. I used to run a lot, but had to stop several times (for months) because I felt I had no energy. Muscle
soreness, as well as various radiating pains, also are a problem. I'm, 49 years old, but I don't believe these problems are due to normal wear and tear. I do know all of these symptoms began to appear after I had been taking Niaspan for at least several months. Thanks, M. Gray

i am 42, have been on simvastatin for 2.5 years, for the last 6 months, have been having really bad leg pains, outer thigh, feels like its burning, tummy troubles, but now i have looked at this site, i feel it must be the statins.am on some many other tablets, and i am always tired but thought this was the beta blockers......

I had been taking Lipitor for well over six years to help lower my Cholesterol count with no know side affects. A problem developed about two and a half years ago with nerve damage that gave me excruciating pain in my shoulder and arm. After an MRI and three cortisone shots I was referred to a neurologist for help. He had no idea what was causing the problem.

About six months after many doctors could do nothing for me, and referring me to a physical therapist, my wife showed me a story in a magazine, which I can no longer find, that talked about problems with Lipitor that had not been properly documented. The article talked about exactly the side effects I was having. The article said there was a problem with nerve damage. It had been well documented that some people had muscle problems, but it was not know there could also be a problem with nerve pain.

I contacted my doctor and stopped taking Lipitor. Two months later, the pain just disappeared. The very day the pain ceased, I had a visit from a good friend of mine who is a Radiologist and who had studied Lipitor because of a problem he was having.

He explained that Lipitor was doing the job it was supposed to do, namely keeping the liver from producing all fats. The problem I was having was that I had injured a nerve and Lipitor was keeping the liver from producing a particular fat needed to help heal that nerve. It seems that the myelin sheath around the nerve needs that fat to help the nerve heal itself, and Lipitor was preventing the production of that particular fat.

Once I quit taking Lipitor it took about two months for the healing fat production to do it's thing. Recovery of the nerves in that arm has been very slow, but they do seem to be healing now.

I thought this was such an important finding that I notified all the doctors I had seen about this problem. To my great surprise I heard from no one. Not even a thank you. I guess that since they didn't find the solution, they just were not interested.

I hope this discussion helps someone else. Thanks for listening.

Started Levaquin yesterday for Bronchitis. Today I started with episodes of Tachycardia, Tightness in the chest, and numbness and tingling in the hands,feet and face. I am a nurse and trust me I will make sure none of my patients leave the office I work at with a script for this class of medication. 1 DOSE WAS PLENTY FOR ME I'M THROWING OUT THE OTHER 9 PILLS ASAP!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

61 year old female, on Lipitor 2002-2005 10 mgs a day. Doc increased dose 2006-current to 20 mgs a day. No muscle problems BUT hair has thinned out dramatically! Doc called today and reduced dose back to 10 mgs for 6 weeks as liver enzymes up with tests last week. Also have tingling in feet. Haven't read all the posts here yet as just found site today but anyone else losing hair and taking drug? If you had hair loss and quit the drug, did your hair come back? If your liver tests were higher and you cut back on the dose, did your numbers go down?

I have been on synthroid for about 6 months now. Some of the side effects I have been experiencing are numerous.I have hair loss, sometimes I get so ill that no one can stand to be around me, my weight has gone up about 30 pounds, my cholesterol levels went sky high so now I'm taking Crestor, I'm bloated most times, I have episodes where my face flushes and gets so red that it feels like its on fire, and now I've just started experiencing burning and aching of the legs, I'm tired a lot too! My doctor said I would lose the weight but every time I go for check ups and get on the scale it just keeps going up. I would like to know if anyone else out there is experiencing the burning and achy legs because I have been tested for everything and they can't find out what is going on. They of course say it's not the medication.It seems to never be. Does anyone feel me??

I suffer from chronic gastritis, not diarrhea, just inflammation, have taken this for sinus and upper respiritary infection. 250mg four times a day. It has helped me with alleviating the constant constipation I suffer from, but it has really made my gastritis worse, to the extent that I am having throat irritation through acid reflux now! Also felt shaky and weak about an hour after each dose, and so very tired, overwhelmingly tired and weak. Have completed the course, but would not wish to take again. I can't have Penicillin drugs because of allergy. VERY IMPORTANT, I was on a statin pill (Lipitor) and was told my the pharmacist to watch for muscle problems, after first day on EM my leg muscles seized up and were cramping badly, I stopped the statin for the duration of the antibiotic. If you are on statins, beware.

I began 50 mg Toprol XL 2 years ago then reduced to 25 mg when palps and blood pressure normalized. Had trouble sleeping. Back in August, I began taking the generic version Metoprolol. One day I couldn't feel my index finger and thumb on right hand and immediate began to worry. I also began feeling depressed and was having terrible panic attacks. Sleeping was non-existent. Also, my chest felt as if it was on fire. Throat closed up and had difficulty breathing. Went to Walgreens nurse and she looked at me funny and said it was allergies to try Claritin and Flonase. DID NOT HELP! Went to the Dr. and he too chalked that up to allergies and gave me a shot. That relieved the breathing symptoms but nothing else. He told me numbness was tendonitis and gave me a "pretty brace." Numbness and tingling did not improve in fact went into other arm which caused me alarm. I went to chiropractor for help...nice massages but still numbness! Then my hands and feet started going cold...I'd had it. Went back to Dr and he put me on Xanax for panic attacks, told me I was depressed and need to see a psychiatrist for mood altering meds. I was ready to slug him! The numbness and tingling are insane! The Dr. to appease me switched me back to Toprol XL...no relief then tried Atenolol. The thing is for a few days while the insurance was figuring out what to pay for, I didn't take meds and began improving. Tried Atenolol and symptoms came right back. Called Dr and was told to just stop altogether...no weaning. Terrible tightness in chest could not breathe...miserable and scary. The next day I got a little better. Sleep improved somewhat but still having trouble with muscles tingling in feet up to knees and muscle cramping in right calve and for arms. Wondering how long this stuff stays in system. Seems to me I should be done...I have been off 17 days and am looking for relief for muscles symptoms...also looking for new Dr...anyone out there know how long this stuff hangs out in your muscles and stuff?????

I have been on Vytorin for about 2 years. Before the drug, I had not aches or pains. My cholesterol levels are good now but the quality of my life is not. I feel as if my joints have aged 30 years over the past two. Lower back pain has caused me to see chiropractors, physical therapists, and surgeons. Now, my feet are hurting so badly that I can hardly walk. I don't know if it's related, but since I've been taking vytorin, my 2nd toe on both of my feet has become crooked and it almost on top of my big toe. I've spoken to my doctor today once again with all these concerns and will be discontinuing the drug for a week to see if these horrible symptoms disappear.

I've been on Diovan for about 9 months and I have all of the side effects everyone else here has mentioned! Weight gain, bloating, fatigue, mood swings, extreme muscle aches- especially in my lower back and legs, hunger, and more! These Drs. are sooo stupid!!!! They tell us to lose weight and then give all of us medications that cause weight gain. I am also diabetic and my Dr. also has me take Humalog insulin- which also causes weight gain! I would enjoy hearing from everyone who has had side effects from Diovan, and I would like to hear about alternative remedies for hypertension. Good luck and Best Wishes to all of you....Kim Q.

I have been on lipitor for a little over two years now. I experience extreme joint and muscle discomfort. I am also picking up weight at an alarming rate. No matter what I do to lose the weight, it's not working. I've had several blood tests, but all come back fine..but I know I don't feel well and I'm having trouble remembering things....

I am totally shocked at what I have learned about Lipitor. My physician prescribed 10mg for me over 4 years ago. No major problems until recently. Severe neck/shoulder pain for about 3 months. Dr said it was a pulled muscle. Gave me Skelaxin. No help. Went to Chiropractor--yanked, cracked, beat, etc--no help. In the past 2 weeks or so I have developed pain in my hips, back and legs. Blamed it on being 52 years old. As I read some of the experiences on here I could relate to each one. I also have gained about 30 pounds in the past 4 years, short term memory is terrible. NO ENERGY> 3 years ago-Dr started me on Wellbutrin for depression, then added Zoloft. I am to the point now I want to get off of all this and see how I could really feel. Not sure about withdrawals. Any comments on stopping the meds?