Muscle weakness fatigue symptoms and conditions

July 8, 2009
I took Lisinopril for 2 months and began noticing soreness and stiffness cramping in my legs. Joint pain and general muscle weakness. Biggest indicator was my inability to ride road bikes (bicycle) nearly as much as normal. I did not have the muscle strength or stamina to ride like before. On one ride I had such sever cramping I had to get pick up, first time in 18 yrs of bicycling. It also states to not use sodium or potassium supplement while on this medicine, which I was doing for cramping. Also because I was borderline hypertension I did not notice any decrease in BP while on this. I have stopped taking this medicine. nn

I started taking REGLAN for gastropoesis 5 months ago. Since I have been tested for MS due to my side effects from REGLAN. Thousands of dollars in medical bills. Symptoms included, numbness and tingling in the extremities and face, forgetfulness, muscle weakness, fatigue, depression, anxiety, insomnia, loss of fine motor skills, confusion, muscle rigidity, etc. I quit taking REGLAN last night hoping that there is no permanent damage. Anyone have any hopeful conclusions?

When my bp, which had always been VERY low, rather suddenly skyrocketed at age 48 (possibly as a long-term effect of the preeclampsia I had 23 years ago when pregnant with my daughter), I was put on 10 mg of Lisinopril. I had diarrhea by that evening. The next day, the diarrhea thankfully disappeared, but other flu-like symptoms set in--mostly nausea and muscle weakness/fatigue. The nausea often made it hard to eat, and the muscle weakness was so bad that sometimes I'd have to stop what I was doing---even typing on the computer--and go lie down. Fortunately, these symptoms abated after one week, and I've been fine for the last two weeks. But now, as my bp is still too high, my Lisinopril is being increased to 20 mg, so I fear getting sick again.