Musculoskeletal symptoms and conditions

I'm an 81yo Caucasian male who has been taking Lisinopril for two years ago. I have suffered through the aches and pains , dry cough lightheadedness , associated with this drug. When I first took 20mg/day, I tracked my BP as frequently as 20 times per day. Some of my symptoms were a result of my BP dropping down to s practice of medicine, MDs do not always have the time to experiment with each patient, so the patient must do some of the logical investigations independently.
Remember, no one knows your body better than you, and your PCP or Cardio MD only sees you for a short period of time. I have tried five statin drugs and cannot tolerate any of them. Alternate, naturally-occurring substances are available.

I started on Advair 250/50 6/28/07 for continued wheezing, bronchitis problems even though I quit smoking 12/25/06. In mid July I began to have Lt knee pain, the dx from the Dr was "arthritis--you are getting older you know" I was 46 yrs old. I got a cortisone shot 7/24 since the pain was so terrible, the shot gave we 1 week pain free, then 8/10 I had #2 shot, same knee, again this shot only lasted 1 week, then pain returned with a vengenance. End of August I had an MRI done on Lt knee due to continued knee pain---this showed a menescal tear. So we are in the 1st week of Sept and the pain continues to worsen, now I have pain in Rt knee also. Grasping at various straws I re-read the Side Effects and Adverse Reactions to Advair. Imagine my surprise/shock to read under Musculoskeletal: arthralgia (Severe arthritic joint pain), bone and cartilaage disorders, muscle pain, muscle stiffness. Also wt gain.
Needless to say I quit the Advair..Even tho I had been on Advair for less than 1 month before my knee problems started . Next week I go in for surgical repair on torn menesci Lt knee, and so far so good with my breathing, but tomarrow I tell my Dr that "I quit the Advair, and the reason why I quit."

I was prescribed 500mgs. levaquin x five days. On the 3rd day I developed cotton mouth, bitter taste on my lips and no matter what I eat it tastes bland at best, bitter usually. I also have a very annoying dry cough that drives me and my husband crazy especially during the nighttime. I also have been experiencing insomnia which has left me the knowledge that night time TV sucks. However, when I do fall asleep its like I'm at the movies. My dreams are vivid and long lasting. They are not fragmented as dreams should be as a result of the cyclic nature of human sleep patterns. When I dream it is literally like I'm watching a movie. I have noticed that even though I get minimal hours of sleep, whenever I wake up I feel like I am fully rested. I usually require 7-8 hours to feel this rested. Interesting how this happened. I wonder if a sleep lab might take a look at this phenomena. I have also developed pain in my rt. knee with an accompanying clicking sound which was never there before. I also have blurring of my vision which made me feel like I need a new prescription for my glasses. This seemed strange since I had a new presription only 4months ago.
So let's tally; systems involved
sensory (taste, vision), respiratory, musculoskeletal and CNS. Gee I got all of this just because I had a UTI. On the more serious side, I was never warned of potential side efffects either by my physician nor my pharmacist. This I feel is a great disservice to the public. If anyone had the bitter taste thing how long did it last? Please comment on other side effects with advice for recovery. As patients taking this drug, we should know what the half-life is, how long it takes to metabolize and how long to detox after discontinuing. Let's hope we will be ourselves again soon, Deb

Newly diagnosed 48 year old male diabetic with moderate hypertension. Was prescribed lisinopril 20mg daily and for a month & everything was fine. I had a pre-existing back problem that got much worse and I was at a loss as to why it flared up until I read carefully the package insert on lisinopril and noticed multiple musculoskeletal side-effects. Upon d/c'ing the lisinopril the symptoms abated and I was curious to see if anyone has had similar experiences. What made the causal connection so difficult was the very slow negative effects upon the back and the relative lack of info on this serious side-effect. Thanks!