Myopathy symptoms and conditions

i have never taken lipitor and i never will but here's a warning for everyone- there is actually a company that sells reports for stock investors and they are advising people to invest in the company that makes the one of the only drugs used in the management of ALS. they predict that the ALS patient population (code for customers) will grow as a result of all the people on lipitor.

ok, aside from the fact that it made me sick to my stomach that wall street views the potential suffering and death of ALS victims as a business opportunity (what else is new?), this is a pretty good indication that there is a link. it will probably take years for "science" to conclusively state the connection and for the FDA to take lipitor off the market

in the meantime, save your own life. if you're not taking it, don't start. if you are, stop NOW! cholesterol is not the enemy

My dr. put me on Lipitor. I took it for 4 months. At the 4 month mark, I was SO depressed, I couldn't function. Crying constantly, no concentration..almost like I was in a trance most of the time. I had problems finding the correct words to use, was paranoid about everything and everyone. I actually thought I must be in the early stages of Alzheimer. Honestly..I didn't know what was wrong with me. I had an actual "pain" in my heart and pins and needles feelings in my fingers and hand on the right side. My forearm became terribly "achy". I went back to the dr. and she said.."oh, I think you're depressed!" Gave me a prescription for celexa (anti-depressant, and sent me on my way. I went home..decided that I WAS NOT going to take an anti-depressant and began to do a little research on the lipitor. Amazingly..I couldn't believe the info that I found with people who had the same symptoms as me! I stopped taking it immediately and within 2 days..my depression and paranoia went away. However I am left with such weakness and pain in my rt. forearm and bicep as well as both shoulders. I went back to the dr. and explained what I had done (guess I shouldn't have mentioned about what i had read on the internet) Because she wouldn't believe that the lipitor would cause that and also said that I had been off of it long enough now(4 months at that point), that any pain that i was experiencing would be all gone! She wouldn't believe me and made me feel like I was crazy!! So..now not sure what to do. Will the pain go away, I wonder? Is there a way to "detoxify" one's self to rid us of all the bad stuff or is the muscle damage permanent and does it keep on going and just keep destroying the muscles, even though we've stopped taking the stupid stuff?? I wish someone could come up with an answer, because I don't know who to go to ask. I can't believe how weak my arms have become since taking it. Will it ever improve I wonder?

I'm 55 year old female and was put on Simvastatin 3 months ago with a cholesterol reading of 6.8. I've been experiencing severe lower back pain, a burning pain in the right side of the groin and severe pain in my right hip and leg. It has become so bad that I'm finding walking difficult. I also have severe itching all over, especially on one part of my arm. I can't take anti-histimes because I am alreading taking beta-histine for vertigo. After reading the postings here I am seeing my doctor this week to have my medication changed. Since I live in the Uk cost is not a problem

4 months ago started on preastatin 20mg increased within 1 month to 40mg; could not stand up without help; stopped statins at that time. CPK done 157, this was done to show me I wasn't in danger of rhabdomylysis, I continue to suffer with swelling R leg and severe pain. Leg is still swollen 4 months later.....I am professional RN in ICU ,,can't really do my job as necessary...Should I file for disability; or does someone have an answer to provide relief for this malady???

I recently lost about 25 lbs and decided after about 8 years of 10 mg of lipitor, to go off of it, cold turkey. I consulted both my MD and my pharmacist about whether or not I should wean, and both declined.

I now feel that my sweats, hot flashes are out of control. I am so hot and tired. I feel as though I cannot do the daily functions that I am responsible for.

I truly had NO side effects that I know of ON the drug. I just figured I'd see how I do now that I lost some weight. I wonder if going OFF lipitor is dangerous?

If anyone knows, please reply!

Thank you!

Yes, I have been taking Vytorin 10/40 for about 10 months, and it did reduce my cholesterol and triglycerides to 'normal', however, I slowly developed (initially) some 3 months back, problems in my left solder, diagnosed eventually as 'rotator cuff' ligament damage, however, it came on slowly and progressively worsened. I had not done anything strenuous to develop such a condition. It became so bad that I was basically redd to using my right arm. On top of this, the muscles in my lower arms became sore and felt strained even lifting a glass of water was painful. My Doctor was informed of increasing on-going muscle problems, did an emzine muscle test, which turned out to be 'clear'. And I also lost my sexual drive gradually.
I went off taking Vytorin a week ago on my own gut feeling, and my arm muscles and left shoulder have improved. I am also hoping no permanent damage. I am moving to a much higher exercise regime to 'burn' cholesterol and reduce triglycerides, and in the mean time look for 'natural' solutions as well.
I am not impressed with the medical responses I got, along with miss-diagnosed muscle / tendon supposed 'rotator cuff' serious problem that developed in my left shoulder, which I suspect may never be the same functionally. I recommend looking at other alternatives and natural remedies, this is my course of action. MM

I was a competitive runner with a number of sub 3 hour marathons under my belt before I was prescribed statins for elevated cholesterol 2 years ago. The first go round was 40mg zocor but muscle soreness and loss of strength started within 2 months. Switched to NIASPAN but couldn't tolerate it. The last 7 months have been on 10mg of Lipitor and now have intense pain in my legs, soreness in my wrist and thumb and swollen feet. I can still run but much less than before and much slower. I regularly go to the gym but have seen a steady decrease in the amount of weight I am able to lift. I have a blood test in a couple of days and will be looking for myalgia again. I have discontinued the statin and don't plan to start again. I was healthier before the DR decided to "help" me with my cholesterol problem.

I was just placed on Cellecept last week- 500 Mg 4 times a day-
for my autoimmune muscular myopathy- I was a body builder 6 months ago- now I can barely make it across the Target parking lot.
I am sure the myopathy is Statin induced as I was on Lipitor-)rather than Prednisone as my doctor said less side effects.
He said I should see improvement in about 6 weeks- is any body taking Cellcept for autoimmune disease?
Thank you.
PS; So far- side effects seem to be weakness- more shakiness-

This is a great site for learning more on this subject where we can get the real facts from real experiences.( Vs. the deception from drug companies who are in the business for profit.)

Lipitor is pure poison, and Dr.'s hand it out like candy. All cholesterol reducing drugs that contain statins can trigger dangerous side effects. Not many of us are informed about the real danger of statins when we are handed the perscription. Inappropriate prescribing of medications will continue to be one of the leading causes of death. And we, the patients,do not always receive enough info. from our Dr.'s about the dangers and side effects from prescription drugs.

I'm 48 yrs. young. Female, small build, (was) healthy and active, happy, and an empty nester! My husband and I had moved to another province and hence had to find a new Dr.

I was prescribed lipitor 10 mg. daily after a routine check up by my Dr. because my cholesterol was a little high.

I started taking it in the winter 2005. I stopped taking it in mid June 2007... My side effects were progressive , drug induced, and it escalated to near disabling.

I knew something was terribly wrong. Was it A.L.S., M.S., West Nile, Lupis, Alzhiemers Disease, or a new designer disease? I did not suspect that the drug lipitor was the cause until much later.

At first, my Dr. said it was menopause. I should mention; since I've quit taking the drug 3 months ago, I have no symptoms of menopause !
At least my Dr. has acknowledged and diagnosed the cause of these profound symptoms." Myopathy as a result of statins."

Signs & symptoms I experienced are as follows;

Severe stomach pain.
Muscle pain, aching , weakness, stiffness, tenderness esp.to the lower extremities. Eventually, I could only shuffle to walk.
Pain in the palms of hands.
Stiff neck, shoulders, arms and lower back.
Trouble getting up from a seated position, and climbing stairs.
Extreme fatigue.
Hot and cold sweats
Night sweats
Fevers. High and low grade fevers.
Ringing in the ears.
Difficulty swallowing, and fear of choking.
Pain in the esophagus.
Memory loss, difficulty concentrating, forgetfulness.
NO appetite, yet a lot of weight gained around the abdomen area.Bloated.
NO taste buds.
Speech affected, slurring words and mispronouncing. Tongue felt swollen.
Trouble breathing at night, would wake up coughing ( and I was not smoking then).
Trouble sleeping.
Loss of balance and coordination.
Blurred vision esp. in the morning.
Sharp shooting pains in the Rt. thigh.

Most of the symptoms have now subsided. I still have some foot pain and leg cramps and muscle stiffness... and poor concentration. Putting this together has been done with great difficulty, as I seem to pause a great deal and forget what I was trying to say. The recovery process is slow but at least it's progress. My Dr. has not prescribed any more medication. I've done my own research, after the fact, and started taking coQ10. and I've noticed a big difference!

Quality of life? Well, I'd rather have high cholesterol and die from that, than be poisoned again by statins. What quality is there, to live an extremely painful, useless and unfulfilling life? We were all guinea pigs, and we paid a terrible price for this! I hope we all can recover from this with no long term side effects.
If you are considering taking cholesterol lowering drugs do some careful research on statin drugs before you take them, and read the testimonies from those effected by them.
sj.

I'm a 28yo male. I have already shared my experiences as guest #31827. This is an update of my condition.

It has been over four months now since I've stopped taking Zocor(which I only was on for one week at 10mg), and there has been little change in my condition. My neurologist said that I have drug induced myopathy and It can take six months to recover from, with 100% recovery, and there is nothing they can do as far as treatment for it right now. I found out that my muscle enzymes were up to almost 6000 when I was on the Zocor. I'm still very fatigued, weak, muscle tightness, bad tension headache, neck stiffness/pain, vivid dreams every night, very out of it mentally(brain dead). I'm a firefighter/paramedic for a living, and have been unable to work because of this. I'm really hoping and praying that I recover very soon and get my life and job back.

Does anyone out there know about any class action lawsutes going on? Has any of you been in my condition and fully recovered, and how long did it take you? I'm young and healthy otherwise. This shows you how powerful and dangerous statins are! If you have any insight for me and others about recovery write back.

I took Lipitor for a number of years until I started having pains in my thighs. I was switched to Provacol and 2 month later I had rabdomialisis (sp) I was paralyzed from the waist down for about 3 months and it gave me neuropathy, myopathy, carpal tunnel in both hands, hypothyroidism and increased my sleep apnea (according to my neurologist) This has been going on for almost 2 years. I am just waiting to see what else could happen. It is the gift that keeps on giving.

Started Zocor in May 2005, took for approx. three weeks. Had been given samples by GP. Stopped June 10, 2005 due to problems. Following is a list of symptoms as they occurred. Head shake, thinking and speaking problems, difficulty swallowing, weakness, low back pain, muscle spasms, pain in legs (especially left leg) Kidney pain, dark urine for one day only, and especially extreme fatigue. GP said was Myopathy. didnt seem to know cause. Continued to get worse untill approx. July 15, 2005. Started phy therapy. This helped to build back the muscles lost but would only build to a certain point. Presently, april 2006, Most of the symptoms have abated but I still have difficulty walking and standing very long. Had to quit working, could not handle. I will keep updating as I progress. This has been some nightmare.

i have a rare form of asthma and am often on high doses of intravenous steroids in the hospital. i get every symptom anyone has noted but I actually steroid induced psychosis (i have no mental health problems generally). I have horrifying visual and auditory hallucinatins.

at National Jewish Hospital they treated this with 1o mg valium with each dose of steroids and Depacote. I can't take Depacote any more because of pancreatic symptoms and the valiun alone helps but doesn't resolve the problem.

Plus I lose my vision almost completely. All the other typical symptoms seem more severe (accordinf to my MD's) than usually experienced so apparently you can be extra sensitive to steroids, i have been tried on Prednisone, Mthylprednisone and Dekadron,

Plus, I have had steroid induced myopathy (where the muscles are eaten away) to the pint of not being able to sit or walk.

I have lost 2 inches of height in 2 years.

and worse of all, my brain seems to just take a vacation - i have amnesia for almost everything that happens.

But breathe first - deal with the rest as it comes.

As far as weight - i have gained 28 lbs in 24 hours (the hospital nurse checked me with three scales) and have lost 39 lbs in 2 weeks -trust me - that is not a pretty sight.

I have had insomnia from November through Feb with psychiatrist doing everything they could to put me under.

If I didn't have a lung disease and was not prohibited from doing almost everything there is to do, I could while on Prednisone clean my entire house cleaner than it has ever been, and then probably achieve world peace because I have never felt so capable of accomplishing tasks (ones that are rote mostly) my family has to watch me to keep me from getting up in the middle of the night and doing something stupid.

And I am a health care professional who usually has excellent judgement. I am a nice person who never loses my temper or says an ugly word but while on steroids I am not only totally unreasonable but verbally abusive at times (many times)

the psychosis thought is the one thing that is really terrifying.

There may be light at the end of the tunnel
I am a 65 yr. old male taking 10 mg. Lipitor for 5 1/2 yrs. In early June,2004
the pain was so intense in my hamstrings, that when I stood up, I would freeze
for seconds in acute pain. On June 26, 2004, I hobbled into my GP's
office telling him of the severe pain in my hamstrings.
At my suggestion, due to reading this website, he pulled me off Lipitor.
On July 4, I started using a cane because of the unsteady gait in my walk.

EMG tests determined that I was 50% weaker in my lower extremities and 10%
weaker in my upper extremities. Started taking 200 mg. COenzymeQ10 ( daily
recommended 100 mg. ) and Cholesterol Essentials ( for my Cholesterol ).
The COQ10 ( a vitamin ) is leached out by statin products and is essential to muscle
building. Went for 5 sessions of rehab to strengthen lower extremities.
Released today Oct. 14, 2004 because they did all they could for me.
Suggested followup with gym program or aqua program for more strengthening.
Today, I walk with no pain and no cane, much stronger than before, still not perfect.
Half my doctors suggest a herniated disc and the other half believe
Lipitor is the culprit. No numbers on Cholesterol level , yet. I will never use
a statin product again. It appears that being off Lipitor for 4 months, and introducing
COQ10 plus some rehab, that my muscle myopathy has lessened considerably.

Those of you who are suffering from muscle achiness should tell your doctors that this is now a recognized side-effect of statins. An article published in the October 1, 2002 issue of the Annals of Internal Medicine concluded "Some patients who develop muscle symptoms while receiving statin therapy have demonstrable weakness and histopathologic findings of myopathy despite normal serum creatine kinase levels." Similar problems are recognized by the American College of Cardiology, the American Heart Association adn the National Heart, Lung and Blood Institute. Their findings are cited in Jane Brody's column in the New York Times (December 10, 2002).
I experienced intense muscle achiness in my legs while on generic lovastatin. Interestingly, for me, this disappeared when I switched to Lipitor.