Night mares symptoms and conditions

My name is Heather I am now 32 years old I took levaquin when i was 29. After i took levaquin I went on a roller coaster ride I have yet to be able to get off of. First when i took it I had the worst night mares i have ever had only to wake up to a splitting headache and a very sore body. took another one the next day same reaction.I figured it was the bronchitis that was causing the problem. on the third day i was worse still I could hardly move. I stopped taking the drug. after another two days i felt better. two weeks later I was out with my father and he noticed a rash on my legs. I was also starting to get little blood blisters. I started to become concerned and the next day after going to the zoo with my family i came home and my legs were swollen three times there normal size and very sore. I put them up just to find the felt like play dough had been stuffed in to them and I had blood blisters the size of pencil erasers. I made an appointment to see the doctor. he said and i Quote " Heather I have No idea what the Hell you have" he sent me to a specialist. between the time of my first appointment and the appointment with the specialist my legs stopped working from the hips down i was 90% paralyzed (not spelled right ) they just wouldn't work right. My ten year old daughter was helping me get to the bathroom. I was soooo sick i had a headache all the time couldn't eat or sleep and when i did it was only for a few hours I couldn't move very well and to get up out of bed hurt so bad i almost fell every morning. by the time i had gotten to the specialist I had gone to the E.R. three times for the pain.and the last time was because my toes stopped moving altogether. at the appointment the doctor ran all kinds of tests checking me for everything from S.T.D.s (which i have been happily married for years) to Lupus. I felt Like and 80 year old Lady And like i said i was only 29. after the extensive tests and everything coming back normal the doctor put me on a steriod. for 4 months i was told i had to take prednisone After the first dose i could move again I still hurt but i could move.But now i had the side effect from that. i was gaining weight like it was going out of style, but at least i could move. after the 4 months things seemed normal kinda. I could move but if i sit still to long my legs go numb not fall sleep go completely numb even if i am standing to long. I am still afraid that i will wake up again feeling like i did that Fall three years ago. I still have problems but im not sure they are tied in but it wouldn't surprise me in the least. I only took three Pills of Levaquin three years ago!!!! How long does this stuff hang on really??????

No energy,aches,pain confusion,deep deep sleep,can't wake up forgetful,bad memory,voices,headaches,night mares,metabolism meaning none,weight gain,

I notice vivid dreams/night mares the first night. The second day I notice thoughts of running of to very far places. The third night severe chest pains, extreme anxiety, irritability, and thoughts of suicide. Now I have been treated for depression in the past but never attempted suicide. After the third day of singulair i wanted to take a gun to my jugular vain in my neck and pull the trigger. Oh the joy of a panic attack.

I have been on Loesterin 24 since Dec 2007 so far it has given me slight discoloration spots two under the breast, two on the shoulder blade and two on my arm, Mild to extreme moods swing, depression, nausea, headache, acne and speratic periods, ranging from a week before the period is suppose to start to two days after the period stops just to start all over again. Night mares and restless sleep patterns have been a usual.
I really do not recommend this birth control to any one but can’t stop taking it for fear of getting pregnant again.

Get well soon! I had mirena for almost 8 weeks. Thank GOD i had it removed 2 days ago. I couldn't take it anymore i want this thing out in my v !!! and I did!! I feel great!!

I wasn't also comfortable making love, i feel like messy all the time, coz im bleeding, i was thinking that the IUD might misplace or something, go swim in my uterus, get bored and go somewhere..huh@!# its not a good feeling and i had night mares too, so its was time...its not worthy to keep it!!

I had surgery to have an errant IUD removed from my abdomen on 8/6. Now, I still feel extreme fatigue but better. I want to start BC pills to maybe help my body. Has anyone done this?

Hi all, I was amazed to find this site. I too have had a rough life for the past eight years! I am going to be 39 in a few days but this story starts back in August 21, 2000. The day that put me in HELL for the next eight years and still going through it. Prior to this day, I had a lot of UTI's and Pneumonia and several times prescribed both Levaquin and Cipro. I did develop Achillies tendinitis but I thought this was due to my active life style, see I was an LPN and a firefighter. So I went for treatment to fix the Achillies tendinitis. This was a foot Dr that of course gave me a cortizone shot in it. I cant remember how much earlier this was that this took place and I am still not sure if this is what did it but as I am thinking back these are the things that come to mind. On August 21, 2000 I was on a fire call and my right Achillies tendon popped off the bone! They took me away by ambulance. The Dr in the ER said to go home with an air cast on, eat or drink nothing and come back in at 10:00am and they would possibly do surgery. Well, I did just that. The orthopedic Doc said oh yeah it is achillies rupture will have to go in and tie back all the little fibers. So away to the operating room I went. They gave me a spinal and just knocked me out. I was awakened suddenly by my Dr. voice loudly saying " Holy shit it peeled off the bone!" And another nurse saying let me see! I came up on my hands and they grabbed me put me back down and knocked me back out! (I still have night mares over that!) Anyway, I spent the next 3 months in a cast. During this time, I was told from over usuage of my left foot, I now was developing tendinitis in my achillies tendon in the left foot! Which this sent me to a wheel chair. They took the cast off in 3 months then I was still no weight bearing for another month. Then i had physical therapy for about 6-8 months with little improvement. I complained to the Dr about the left achillies tendon and he said he would not do anything about it unless it too popped! So now many Dr later, and many many medications tried and many surgeries later, and now diagnosed with Lupus, Sjogrens, and Fibromyalgia, the most my rheumatoligist says is I have a connective tissue disorder, and taking cancer medication (Methotrexate) I am now disabled at 39! My life taken from me. I have situational depression, panic attacks, sleep trouble, Suffer from post traumatic stress, nightmares, basically my life is a mess and it is over. On July 1, 2008 I had to go to the ER cause I was sick. I had been run down and feeling bad and sleeping a lot, disoriented, couldn't stay awake. They found I had another UTI and a sinus infection. The Dr Says we will put you on Levaquin and that should take care of both problems. So he left, it took me a while for it to sink in that I should stay away from that drug, so I caught him and told him, he said to me that this was only found to be in kids while they are young and developing that it causes tendon rupture, and besides he said, one dose will not hurt you. I took 5 pills, one a day. Since then I have been in so much pain all over my body it is unreal! It still took me days to figure out that it was the Levaquin doing this to me! I feel like at random someone is sticking a knife in different muscles in my body! I felt like I had done Tie bo for 24 hours straight! Even my butt muscles hurt so bad to sit here and write this email! I have days when I cant even use my hands! Write my name with a pen. I am not sure if this is all due to these drugs, but I am most miserable and not a bit better. I may have just made it worse by taking this last round of them. Has anyone else had this kinf of symptoms?

In September of 2007 my then 13 year old daughter was put on Singular for mild asthma. At the time she was a straight A student, vice president of our school and a popular girl who's guidance counselor described as "the glue of her grade" because she was so well liked. In November she told me that she was struggling with advanced Latin and Science. She asked to drop down to on grade Latin so we did. In December her science teacher notified us that she had a C average. She told me that she thought she had ADD/ADHD and she couldn't keep up. At the same time she was having a lot of problems with friends at school and we just attributed it to being 14. 3 weeks ago we discovered that she is significantly behind in English and it was then that she told me that she is been having horrific night mares. She said that they usually involve someone killing her or her killing herself. She said that they were so graphic that she couldn't repeat it out loud. She also said that she would feel waves of anxiety that would come over her at school and she would act "witchy" to the kids in her class for no real reason. She said that sometimes when she is trying to do her homework she will read the same passage for 2 hours and still have no idea what it's about. She also said that the suicidal thoughts from her sleep happened during they day and that she had thoughts of her harming herself. Fortunately her pulminologist told us that this may be caused by singular and we immediately took her off of it which was 2 weeks ago. She has only had 1 "bad dream" not even a nightmare since. She had one anxiety attack 3 days after she was off it and she describes her moods as the "cloud lifting....slowly". Now, we have to pick up the pieces. Her grades have suffered, her friendships have suffered and most of all her self esteem is very low. I'm grateful that we found out the cause but I feel as if my daughter lost a year of her life and I worry that because Merck won't admit there are side effects we can't find out how long it remains in their system. Is anyone else concerned about the long term affect and has anyone pursued a class action suit to try to get this drug tested properly?

My four old son has been on singulair for about two weeks. The change from wheezing/coughing attacks at night and terrible allergies during the day has been amazing. They are almost non-existent to this point a great plus. However, a i stress however his behavior and speech has been VERY INAPPROPRIATE and quite frankly it concerns me. He now states "im a bad boy" and "i dont listen" and his mornings are very testy to say the least. Granted these sound like normal 4 yr. old sayings that he would pick up from other children on the playground but how do you explain them happening almost simultaneously with his taking singulair. I find it very hard to believe that it is a coincidence and that these are normal things for a 4 yr old to say/do when all other things have remained the same. My advice is to diligently watch your child for these warning signs and find other remedies if you have reservations. Im not promoting natural cures but i am leaning toward a diet change for the whole family and consulting my doctor for food allergen testing. I hope this helps. Be Well.

Quinolinic acid and neurotoxicity:

Montelukast contains a quinoline radical. Quinolinic acid, a well known damaging neurotoxin that kills neurons, can be produced from a quinoline and hydrogen peroxide. The body produces hydrogen peroxide for a numbers of reasons. White blood cells produce hydrogen peroxide when activated by antigens such as bacteria, virus, fungus etc. It is also produced under conditions when the body is stressed. It is also produced in the gastrointestinal track.

If we knew how montelukast could break up to free the quinoline radical, then we might be able to define a number of different scenarios under which hydrogen peroxide could cause montelukast to generate the neurotoxin quinolinic acid.

If we could prove that montelukast is capable of produce quinolinic acid under unusual circumstances (doesn't happen to everybody), then we would have a very good explanation for all of the psychiatric adverse drug reactions that are mentioned here which include hallucinations, anxiety, depression, suicidal ideations, night mares, etc. etc.

Anyone looking for answers should try to pursue the possibility that quinolinic acid is causing bad side effects. I wish that I was much better at chemistry. I am stuck here at the moment. I keep hoping that somebody else with more expertise will come here to tell us how it happens.

Can Statins Cause Chronic Low-Grade Myopathy?
Statins (hydroxymethyl glutaryl coenzyme A reductase
inhibitors) are highly effective drugs for reducing serum
cholesterol and low-density lipoprotein cholesterol levels.
Clinical trials have shown that they also reduce risk for
coronary heart disease events, coronary procedures, and
stroke by about one third (1). Millions of people in the
United States and worldwide are being treated with statins.
In clinical trials and in clinical practice, statins have proved
to be remarkably safe.
The one notable side effect of statin therapy is myopathy.
A small fraction of patients who are treated with
statins will develop severe myopathy (2). In the worst cases,
severe myoglobinuria, acute renal failure, and even death
can occur. The incidence of severe myopathy is low, perhaps
1 in 1000 patients (2). Predisposing factors for severe
myopathy appear to include advanced age, relatively low
body weight, female sex, certain medications, use of multiple
medications, multisystem disease, and acute illnesses
or major surgery (3). If statins were avoided or used in low
doses in these circumstances, it is likely that the incidence
of severe myopathy could be greatly reduced.
Less severe forms of myopathy undoubtedly occur. In
some patients, fatigue and muscle pain and weakness develop
with moderately high serum creatine kinase levels
but not acute renal failure. In these cases, the myopathy
resolves when statin therapy is discontinued.
Still more patients report various muscle symptoms—
fatigue, pain, and muscle weakness—but have normal creatine
kinase levels. These symptoms probably are unrelated
to statin therapy in many patients. In middle-aged and
older people, muscle, joint, and tendon symptoms are very
common. Naturally, if a patient takes a medication that is
believed to produce muscle problems, symptoms are often
attributed to the medication. On the other hand, the major
controlled clinical trials have not detected a higher prevalence
of muscle symptoms during statin therapy versus placebo
(1). This failure of detection has generally led clinical
trialists to conclude that statin-associated myopathy with
normal creatine kinase levels essentially does not exist or
that, if it does exist, it cannot be detected above the “background
noise” of muscle symptoms in the general clinicaltrial
population.
Many physicians in clinical practice nonetheless believe
that they can identify a subset of statin-treated patients
who have a unique set of statin-related muscle symptoms.
Some patients clearly relate the onset of muscle
symptoms to initiation of statin therapy. These symptoms
may abate after discontinuation of therapy, only to reappear
when statin therapy is restarted. The number of such
patients is not large, and thus it may have been impossible
to identify them in large clinical trials.
In this issue, Phillips and colleagues (4) report on a set
of studies in four patients who had muscle symptoms during
statin therapy that resolved during placebo use. Quantitatively
measured muscle weakness also resolved during
placebo use. Muscle biopsies were performed in three patients
during statin therapy and then during placebo use.
Several pathologic changes were seen on biopsy specimens
obtained during statin therapy: increased lipid content of
mitochondria, fibers that did not stain for cytochrome oxidase
activity, and ragged red fibers. The authors suggest
that these patients had statin-associated myopathy with
normal serum creatine kinase levels.
Despite the study’s small size, we cannot dismiss these
observations as random variation in muscle structure.
However, these highly suggestive results are clearly preliminary.
The number of patients was small, and all appropriate
controls were not used. Nonetheless, this study is novel
because it used quantitative measures of muscle strength
and muscle biopsy to address the question of myopathy
with normal creatine kinase levels during statin therapy.
To be confirmed, the current data would have to be
extended to many more patients in whom muscle symptoms
are closely correlated with statin use. Reproducibility
of symptoms during therapy and symptom resolution after
discontinuation of statin therapy would be necessary. A
definitive study would have to be carefully designed and
executed. It would need to be double-blinded and placebocontrolled
and include sufficient numbers of patients to
provide a valid statistical comparison. In addition, investigators
would have to carefully consider the appropriate
selection of patients. The development of a registry of candidate
patients at multiple sites could facilitate a multicenter
study.
Is a carefully controlled, sizable study of this type
worth the investment of time and effort? To date, no evidence
indicates that prolonged statin therapy leads to permanent
muscle damage or progressive myopathy in patients
with normal creatine kinase levels. Controlled
clinical trials attest to the general safety of statins, and
symptomatic side effects appear to be limited to a relatively
small proportion of treated patients. In addition, no therapy
prevents or treats statin-induced myopathy, short of
withholding the drug. On the other hand, statins are being
prescribed to millions of people, and are usually continued
throughout the patient’s lifetime. It is certain that statins
cause myopathy in some patients. For these reasons, a valid
argument can be made for a more extensive study of lowgrade
myopathy in patients treated with statins.
In the meantime, physicians should recognize the great
benefit of statin therapy in high-risk patients and their
documented safety for most patients. For high-risk persons,
the proven efficacy for preventing cardiovascular disease
outweighs the unlikely possibility of permanent muscle
damage. Phillips and colleagues’ preliminary results
certainly do not provide adequate information on the spec-
Editorial
www.annals.org 1 October 2002 Annals of Internal Medicine Volume 137 • Number 7 617
trum, scope, or prognosis of myopathy with normal creatine
kinase levels during statin therapy. For these reasons,
prescription of statins for eligible patients should continue
despite the current results. Moreover, before discontinuing
therapy, physicians should carefully evaluate any patient
receiving statins who reports muscle symptoms. In most
cases, the symptoms will be found not to be consistent
with chronic myopathy, and often they will not be related
temporally to statin treatment. High-risk patients in particular
should not be deprived of major cardiovascular risk
reduction just because they display symptoms not clearly
documented to be closely related to statin therapy.
Despite these comments, the actions of statin on muscle
metabolism and structure deserve further investigation
to clarify the confusing area of low-grade myopathy apparently
associated with statin use in a few patients.
Scott M. Grundy, MD, PhD
University of Texas Southwestern Medical Center at Dallas
Dallas, TX 75390-9052
Current Author Address: Scott M. Grundy, MD, PhD, Center for
Human Nutrition and the Departments of Clinical Nutrition and Internal
Medicine, University of Texas Southwestern Medical Center at Dallas,
5323 Harry Hines Boulevard, Y3.206, Dallas, TX 75390-9052.
Potential Financial Conflicts of Interest: Honoraria (from Merck &
Co.; Pfizer, Inc.; Bristol-Myers Squibb; and Bayer); Grants (from Merck
& Co. and Pfizer, Inc.)
Ann Intern Med. 2002;137:617-618.
References
1. Executive Summary of The Third Report of The National Cholesterol Education
Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment
of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA. 2001;
285:2486-97.
2. Staffa JA, Chang J, Green L. Cerivastatin and reports of fatal rhabdomyolysis
. N Engl J Med. 2002;346:539-40.
3. Pasternak RC, Smith SC, Bairey-Merz CN, Grundy SM, Cleeman JI, Lenfant
C. ACC/AHA/NHLBI clinical advisory on the use and safety of statins (1)
(2). J Am Coll Cardiol. 2002;40:567-72.
4. Phillips PS, Haas RH, Bannykh S, Hathaway S, Gray NL, Kimura BJ, et al.
Statin-associated myopathy with normal creatine kinase levels. The Scripps Mercy
Clinical Research Center. Ann Intern Med. 2002;137:581-5.
© 2002 American College of Physicians–American Society of Internal
Medicine
Editorial Statins and Low-Grade Myopathy
618 1 October 2002 Annals of Internal Medicine Volume 137 • Number 7 www.annals.org

Update: I have spent hours searching scientific data bases for articles on Singulair. So far this is the most direct reference to adverse drug reactions and Singular.

For anyone who wanted to print the article from the Swedish researchers that stated that their study suggested that montelukast (singulair) should be investigated for adverse psychiatric drug reactions, I was able to find a link with open access to the public. So far, this is the only article that I have found. I am still searching through databases. This link should work if you cut and past. I am sure that all doctors would appreciate the opportunity to read it for themselves to see what they think.

http://www.biomedcentral.com/1472-6904/8/1

Individual case safety reports in children in commonly used drug groups – signal detection Gertrud Brunlöf , Carina Tukukino and Susanna M Wallerstedt Department of Clinical Pharmacology and Regional Pharmacovigilance Centre, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden author email corresponding author email BMC Clinical Pharmacology 2008, 8:1doi:10.1186/1472-6904-8-1 Conclusion In conclusion, the present study indicates that ADRs are reported for commonly used drugs in children. The number of ICSRs varies in different groups of drugs. A possible signal for montelukast and psychiatric adverse drug reactions was found, which should be further explored.

Please don't forget to print the Tables which open on a separate page. Table 2 lists the specific side effects that they found which include anxiety, aggression, night mares, pain, and several others.

I would also like to point out a table that was in the Swedish study that showed what the adverse drug reactions were. It lists that children had night mares, aggressiveness, sleep disorder, abdominal pain, increased appetite, anxiety, fatique and several others. All of these symptoms are similar to what we are reading on this board.

This study was done in a foreign country before anything was ever announced in the American media. If you take this article to your doctor, please don't forget to print the tables. There is a link on the page.

See this link for the article.
http://www.biomedcentral.com/1472-6904/8/1

Individual case safety reports in children in commonly used drug groups – signal detection
Gertrud Brunlöf , Carina Tukukino and Susanna M Wallerstedt
Department of Clinical Pharmacology and Regional Pharmacovigilance Centre, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden
author email corresponding author email
BMC Clinical Pharmacology 2008, 8:1doi:10.1186/1472-6904-8-1

Conclusion
In conclusion, the present study indicates that ADRs are reported for commonly used drugs in children. The number of ICSRs varies in different groups of drugs. A possible signal for montelukast and psychiatric adverse drug reactions was found, which should be further explored.

Table 2
Description of ICSRs for children in the ATC code R03DC. All ICSRs concerned the substance montelukast.

Age (years)
Dose (mg/day)
Treatment duration (when known)
ADR
SPC (Yes/No)

ADR, adverse drug reaction; ICSR, individual case safety report; SPC, summary of product characteristics
Brunlöf et al. BMC Clinical Pharmacology 2008 8:1 doi:10.1186/1472-6904-8-1

Oh my god!!!! My poor daughter. My daughter Karilynn has been taking this drug for about 8 months now. She is 2 1/2 years old now. All of the sudden she had a drastic change in behavior, sleep and eating patterns. She began with sleep problems. She would wake up in the middle of the night screaming that the green monsters were after her. I chocked it up to night terrors that weren't explained. Then she started waking up screaming that her "bottom" hurt but would point to her stomach. She quit eating, cried all the time, started acting out randomly. My little girl who had never had discipline problems started randomly hitting and biting me. It wasn't even when I would discipline her for something. She would literally come up and bite me out of no where. She throws huge tantrums now. The daycare lady even asked me if something was going on at home because she was doing strange things there also. Not knowing what was wrong (but trusting my mother instinct that there was SOMETHING wrong) I started to think that maybe she was being abused. The night mares, the random pain.... I even had a breif moment where I thought my grandmother was hurting her. I want to throw up thinking about that now. I took her to the pediatrician, who ran every test imaginable to "rule out any physical reason" that could be causing all of these symptoms at once. Test after test came back negative. I actually have the number to the psychologist that does "play therapy" sitting in front of me because we were seriously terrified that someone was hurting her. Little did I know it was us!!!! I called tha asthma dr. yesterday after seeing the news story and he told me that my concerns weren't really valid and that it sounded like she was being a "typical" two year old. That really made me angry. After reading all of these accounts there is very little doubt in my mind that it is the medicine. It all makes sense now. Halleluah if it is such a simple fix!!! I was worried my daughter was being ABUSED!!!! What an unimaginable feeling for any parent!! I quit the singulair last night against the asthma doctors "urging" and gave the daycare lady a heads up. Its sad to say but I pray this is all that is wrong with my little girl!!! If someone files a class action suit please let me know. Also if there is anything more I can do to make sure someone else doesn't go through this let me know!!!!!

I have a seven year old Daughter that has been on singular for 6 years. The first 3 years she only took it occasionally but the last 3 years she as taken it every day. Also in the last 3 years she has had trouble sleeping all the way through the night she would wake up because of night mares and was afraid of sleeping alone and having mood swings that you would not believe she would go into rages that would leave me in tears because of not being able to help her and after about a year of that i took her to a Psychologist she was given a sleeping pill and was tested for learning disabilities. when they test a child they also ask the parent and the teacher a lot of questions about different situations the results of that test made it sound as if all of this behaviorally problems with my daughter was my fault be cause i did not have a good support family i think that was because i am a single mother but they also said there was nothing essentially wrong with my daughter. all of the things that i have read tonight sound just like the problems that i have had with my daughter and my daughter will not be taking Singular i know that they say that we should not be stopping the medication without talking to our doctor but if singular is the reason my daughter is acting this way then i can handle a runny nose better than a scratching bighting hitting whirlwind that she becomes in her rages

My 9 year old daughter has been on Singulair for almost 6 months. Her asthma symptoms have completely gone away. She no longer has her night time cough, post nasal drip, and frequent colds due to allergies. However, she has gained almost 10 pounds, has been tired and has complained of sore muscles. She has had night mares and leg cramps at night. She has also had frequent mood swings. I thought this was just due to her age. She used to be a sweet, kind, patient girl most of the time, and she has been quick to have temper tantrums, cry and/or yell at us over the silliest things. She is a very active girl- dance, soccer, swimming, etc. and she eats healthy foods for the most part. I could not understand why her face was looking so bloated and her pants were all getting too tight all in such a short amount of time. We are taking her off of this medication immediately!

My four year old son has been taking Singulair for Astma and allergies for three monthes now. He has always been very bright, so when he could not answer simple questions, and started getting in trouble in K4 class, we wondered what was happening. We talked to teachers and were about remove him from the program. He has aggresive behavior, problems thinking or remembering, and generally crabby. He is complaining about night mares every night, and is tired. After reading all these comments, I think we are going to take him off and see how he acts in school. We will let you all know how things work out. Thanks for letting us know about Zyrtec, we will avoid this as well.

somehow since ive been taking this pill ive had the worst nightmares (like its 5:30 in the morning i cant sleep night mares) ive been a total b*tch, for no reason at all.
my face looks like crap, ive never had acne or an oily face.. i now have both

My daughter is 5 years old and has been on singulair for 1 week. i have already noticed a dramatic change in her behavior. she has become irritable, mean, nasty, and emotional. she has had me in tears on a daily basis. she has turned into a monster. we will be calling the doctor in the morning!

I took singulair for 5 years while I was in college. From ages 18-23. I had violent mood swings and anxiety (which I attributed to the stress of school, but very uncharacteristic for me), I had vivid night mares, hyperactivity, and worst of all extreme joint pain with tingling in extremities. I am now 26 and I still suffer from joint pain, tingling extremities and night mares, my mood swings and anxieties are lessened but are still present and I make a concious effort to quell them. My hands, knees, wrists, fingers, spine and hip make me feel like and octegenarian (an 80 year old). The pain is so great that I must eat 800mg or more of ibuprofen a day. I am too young to have these issues and I have cared for my joints well with lots of low impact excercising and glucosamine chondroiten. I am glad that I found this site, it explains my severe pain for the past 7 years. I am going to talk to my doctor first and then my lawyer. Class action law suit here I come!!

My Daughter has been taking Singulair for 4 weeks and has demonstrated many of the sideffects listed in these here pages.
Before Treatment she was a well adjusted little girl who cared and loved her younger sister of about 1 year 8 months and was very easy to care for now she actsa like she is possesed by some freakin monster she is calm one second and just explodes in a fury of rage kicking screaming .
She also has night mares shuddering boddy itchy skin and has scratched it that bad it bleeds extreme irritibility fatigue tantrums that last an hour or so i stoped treatment today all of the information i have read on www with google searches have all but 3 percent reported good treatment with no apparent unwanted effects.

i was on topamax for back and knee pain my doctors took me off it when i stopped going to the pain clinic my phych. thought it would be good for anxiety and depression so she started me back on it and 100mg it shocked my system and now my hair is falling out. i will keep losing hair for up to 2 months most people only lose 50-100 hairs i can lose up to 50% of my hair. so i will never take topamax again....besides i hated all the tingles in you hands, face, and feet, the night mares ect....

i have been takig ambien for almost 2 months now, its awsome, i can sleep when i want and i can control regular sleep. however; since i have been taking it i feel the next day very unaware of my surroundings, very confused,. its really hard for me to tell reality from the really bad night mares. i am completely confused. i cannot sleep with out something, this medicine is not right for someone like me who have insomnia every day. it is definetly for short- term use. and plus, after you use it for too long of a period, you become amuned to it, and it no longer works. my doctor told me to try and take it only every 3 dayes, so that way it would work.

I repeat what I've seen here in so many posts. I can't believe it took so long, how did I not realize, my poor child has suffered etc... etc... His side effects were: restless sleep, night mares, NEVER slept through the night. Less and less willing to go to bed at all. Combative, aggressive, began biting, short tempered. Extreme and rapid mood swings, physical, throwing toys and household items. Disinterested in socializing with other children, afraid to be with anyone other than immediately family. Poor self image ("I'm a bad boy"). Plus others.
I have a similar story to many. My 3 year old has been on Singulair for over a year. He had sleep disturbances early on, but the doctor changed the time to administer the dose and it improved... at first. The unfortunate thing I have realized with this medication is that the side effects are gradual and varied. This makes it difficult to make a connection especially in small children. It wasn't until he had a frightening 4 hour night terror episode last week that something clicked, I did a web search, found this website and realized it was probably the singulair. I stopped giving it to him immediately. Within days his behavior improved. Within 2 nights he began sleeping through the night, his personality is completely opposite of what I've dealt with for the last year. He is evolving each day and while I feel guilty for not catching it sooner, I am so elated to watch him shine. I thank all of you for sharing this information, without it I may not have yet realized that my son was suffering.

I contacted the company and they said that all these things have been reported "after marketing" what this means to me is that salespeople can market this to the medical community and not mention theses side effects because they did not occur (or were not documented) during the trial period. I suggest that you share your story with your friends and get the word out. If this medication works for a patient that's great, but I think patients/consumers have the right to know what they may be getting themselves into.

I'm a 45 year old female , I have been taking singulair for the past two years along with sevreral other medication percribed by my family dr. over a year ago. I have had several proublems with leg and feet cramps that have sent me to the E.R. several times I just thought there was something elese going on. than after reading some of your statements it makes every thing quite clear maybe this is the answere to my proublem is to stop taking this medication for a while and see if thats what it is . I have trouble sleeping as well like one of you said the night mares are awful .
and the mood swings as well I never really conected it , my childreen will say mom whats the proublem are you made and for no reason at all I will just snap at them or any one for that matter that just happens to cross my path at that time .
thank for the input maybe some one will help with all these side effects and stop giving out this medicen.