Painful skin symptoms and conditions

Has anyone experienced anal fissures? Since Advair has mucus forming as one of it's side effects my husband and I were curious to see if anyone else was reporting weeping around the anus which is causing very painful skin irritation and a fissure. He also has terrible leg cramps while sleeping at night, hair loss, mouth sores, thrush in his throat. He has been on advair for over two years and we are now reading of all the same side effects that have been plaguing him for some time now. The anal fissure is difficult to discuss, but I did read of a mother below that wondered if her son's soiled underwear could be related. Does anyone else have this symptom?

raised liver enzymes,nausea ,amnesia,muscle pain in legs arms and hansdsanfeet are painful, skin irritation and rash have been taking simvastatin for about nine months

hi, i started in march with the patch and after developing a painful skin irritation i switched to yasmine, (i was put on birth control to help with my terrible cramps) since i started the pill i have gained about 15 lbs. and i am moody, and depressed (mostly because of how i look) i have even gained weight in places i never have before. i am very mad about this and i wanted to know if any one else has gained weight from this pill. oh 10 of the 15 lbs were gained since may.

thanks,
Amy