Peripheral neuropathy symptoms and conditions

I am 17 years old and i got the three vaccinations of the Gardasil and ever since than i have experienced a lot of pain in my lower stomach area all the time like i have cramps. I have lower back pain all the time. Migraines run in the family and i usto to get them once in a while and now i get them at least four times a month. I dont know if this has anything to do with it... but im in pain all the time and, my mom wont talk to me because she thinks im lying and i dont know what to do.

Murdered by Levaquin.
This may be hard so bear with me. I need to give you a little background to show what an injustice (criminal you be the judge) happened to my soulmate. Her lifelong dream was a humble little spot in the wilderness and at 58 and on a disability we were able to make that happen; and she was happier than I'd seen her in years. Existing conditions included depression, anxiety, fibromyalga and chronic fatigue, and a thyroid condition that she got from over radiation for Graves disease many yrs. ago. Oct. 07 she came down with pnemonia and made a trip to ER. the Dr. saw something he didn't like so prescribed Levaquin. She left there sure she had lung cancer. Three days into a 10 day course her lower extremities became extremely painful and swollen, a call to her GP was never returned. We thought she was experiencing some effects of pneumonia or cancer. 2-3 wks. later a dr. appt. where she was in such bad shape she had to wear my shoes and be carried from car to wheelchair she could barely walk. An alternate dr. saw her. got xrays prescribed more levaquin and prescribed water pills for her swollen lower extremities. 2-3 weeks later side effects much worse has now traveled up to her midsection (peripheral neuropathy) she is now wheelchair bond going to dr. office and guess what lung hasn't cleared up yet so more levaquin with no solution or idea what is happening to her body ( she was terrified and in horrific pain. So she was prescribed 3 courses of levaquin and ignored the blatant side effects. The next several months at home were hell, the neuropathy continued up her body, she could no longer feed herself or hold anything in her hands. Every day the pain and frustration were unbearable and she cried for hours at a time. I couldn't get her to go to hospital as by now we knew what we were dealing with PN and it is irreversible and she knew she was dying and if she left she'd never see her dream home again. We finally got her to the hospital, they wouldn't accept my Achumes Razor and suggested numerous things conducted numerous tests including a Gallum scan and still no answers. She deteriated fast. She was within a week about 63 pounds and suffering severe sycosis with hallucinations. She experienced depersonalization. She had severe pain to the touch. I now know she is going to die and I'd promised her I'd never let her die in an institution but we could get no home care. They now wanted to kick her out of hospital after 3 months and suggested a hospice and although terminal she was undiagnosed so did not qualify. I have seen both parents a brother and numerous people die from a variety of ailments but this was truly a horror show esp. the psycosis and pain she was in. It scarred my heart and soul forever. No insurance so I am fighting to keep our dream home and keep her memory alive, made it a year but the future is uncertain. She died July 5 07, 2 days after she died the FDA put out a black box warning label so how come every time i insisted it was that poison they would not take me seriously. I now know what drives people over the edge to retaliate in some way. In Canada I don't think there is any class action happening, but in everybody that knew about it it would appear like gross negligence at least giving it to her 3 times after showing adverse reactions after first course. She was stolen away form me and her daughter just as she had reached peace and serenity. It breaks my heart continually and I don't know what to do with this rage I feel. It is now 13 months and no autopsy, apparently a hold up at pathology. Feel free to comment I really can't believe she's gone I haven't disposed of anything or even changed the house in any way.
M.

Ok...now I am really angry. I posted in early June. I am 7-8 weeks out from stopping the drug (only took for 2 weeks) and, while I feel better in the am, I continue to have "attacks" mostly at the end of the day after work or when going to sleep. I have minimal dry mouth/cough (keep drinking water/peeing constantly but ok because I am eating foods to dump water which is why doc wanted me on this poison to begin with). The feeling woozy and nausea has subsided. I continue to have racing heart (happens when about to fall asleep and causes anxiety/insomnia), sharp pains all over the chest and in left arm (constantly think I am having a heart attack/stroke), tingling/burning in hands/feet, and to top it off shooting warm burning pain (very annoying) up and down legs (this is new). My doc told me to get off all my supplements (because he knows nothing about them and thinks they are complicating the picture...now I think he is ignorant). I restarted my CoQ10 which is protective for the heart and the racing has stopped so far (been a few days). In my research, most of the symptoms fall under "peripheral neuropathy" which can be caused by toxicity from drugs. Natural treatments suggest making the body more alkaline and detoxing the organs by eating nutritious foods (organic when you can), exercise, drinking lots of water (with lemon and cucumber slices which make the body alkaline and purify the organs) and taking alpha lipoic acid. To treat the neuropathy make sure you are getting enough vitamin C, E, and B complex with B6, B12 and folate/folic acid (I take B100 caps). Please research these before taking anything and make sure its right for you. I used to say check with your doc but, in my experience, most don't know about natural treatments. I will post again in a week to let you guys know how its going. Best of luck to all.

I'm sorry if someone has covered this already... my grandmother is actually the one on Prednisone because she was diagnosed with peripheral neuropathy about a year and a half ago and I believe they recommended it to help her strengthen her muscles so she could walk. It has really taken a terrible toll as she is now unable to walk, and even using a walker can be stressful and difficult. Once she was put on Prednisone they continued to increase her dosage and because of it she now has terrible tremors. It kills me to watch her go through this and wish that I could fight the illness for her. I just want her to be able to eat without feeling so stressed out because her hands aren't steady. The doctor did say that the medication is causing her tremors, and we were relieved to find out that it wasn't Parkinson's, and now they are beginning to wean her off of the medication but she is still taking it at the moment. If anyone has finally tapered off from the medication, who originally had tremors, did you find that your tremors did go away once you were off the medication? How long before the shaking stopped and you felt better? I just want to give her hope that after she is off the medication there will be some relief. I feel awful knowing there is nothing I can really do but support and be there for her, and do some research. If anyone could help me with my questions it would be greatly appreciated. I'm sad to hear other people's terrible issues with this medication and as far as I know I have only heard negative responses to this drug, so it's unfortunate that in this day and age they haven't found something safer that has the same effect that doctors are looking for in a medication. I wish everyone a safe and happy recovery.

For those of you taking this drug and want to get off, please know it takes 3-4 weeks (longer in others depending on your metabolism) to be "totally" out of your system. Don't think you'll feel better in a few days. Give it a least 6 weeks to show significant change in your symptoms. I know, my husband took this and was having mental sluggishness, depression, confusion which led to many other tests. He has been off the drug now since Sept 08 and off the anti-depressant too. Guess what...no depression has returned since being of this drug. He's back to an aspirin a day, what he took before this nightmare began. Anybody taking this drug should stop immediately. It's the drug from hell!

I have been on Topamax since August 2005. This spring I began to have odd problems that I did not attribute to the drug. In April, my doctor prescribed Lasix for swelling in my legs and feet. In August I developed peripheral neuropathy in my legs and feet and began experiencing numbness in my chin and lower face. My doctor prescribed Lyrica for the peripheral neuropathy. Also in August, I began experiencing extreme fatigue and sleepiness. I became depressed and irritable. By September was falling asleep everywhere--even driving. I was exhausted because I awoke from sleep feeling totally unrested. I had a sleep study done and they told me I spent only 25% of the normal amount of time in the two deeper stages of sleep. At the beginning of November, I suddenly became plagued with excessive thoughts of suicide one Friday evening. I decided to stop all my meds, except the antidepressant. Within 48 hours I felt MUCH better. No obsessive thoughts and no more falling asleep. I felt like a giant weight had been lifted from my shoulders. By Thursday I was feeling rested when I awoke in the mornings. I looked up all my meds, including the clinical trials with ALL the side effects and recommendations on Tuesday of that week. Lasix increases the potency of the Topamax and has many of the same bad side effects as the Lyrica I was prescribed--sleep disturbance, depression, dry mouth, etc., etc. Since stopping those medications the first of November, Topamax, Lasix, and Lyrica, I have returned to normal. Even the peripheral neuropathy is MUCH better. No swelling or sleepiness or fatigue. No more irritability or deep depression. Definitely no thoughts of suicide. I can taste food again. And none of the migraines for which the Topamax was prescribed. My doctor is pleased that I am feeling so much better and concurs with the action I took. The medications were apparently interacting with one another and multiplying the intensity of the side effects. So, if you take multiple medications, please go to the clinical studies themselves and read about ALL the side effects uncovered in the studies. On the prescription information we get at the pharmacy, it lists only those discovered at "high incidence", including interactions with other medications.

I have been on zocor for over a year, about 8 months ago I began to have pain in my left arm, got and injection and it was better it started again in my left arm , this time there was pain , tingling, numbness, swelling , it got better but it moved to the right arm which is twice as bad, I am often brought to tears from the pain..I sometime describe the pain like shutting your hand in a car door. My Dr keep giving me the same meds.

I have been on lipitor about 4 yrs. I am a runner and keep tract of my times. I have been losing about 4% of my speed each year and have recently had a large amount of muscle fatigue. Today a ran a 940 pace and thought I was not going to make it home. Three years ago my average pace was 805. Could the 20mg dosage be causing this problem?

I have been taking simvastatin since June 28, 2008. I am 44 years old and have always been majorly active with my 17 year old daughter. Recently I have become chronically fatigued so much as to want to go back to bed within 2-3 hours after I get up in the morning, (definitely not me). I have felt spaced out,depressed to the point of wanting to cry all the time, have severe back, hip, knee, leg, and hand pain. I go to pain management for my back and hip problems (past surgery), but the usual pain has been intensified over the last 2 months and I wasn't sure why, until i decided to check out the Simvastatin to see if it has made me put on a few pounds, and boy have my eyes been opened!!!!!!!!! I AM STOPPING THE MEDICATION IMMEDIATELY!!!!!!!!!!!! Thanks to all who have spoken up, I wish I would of checked on this sooner!!!!! I'm calling my Dr. first thing in the morning!!!!!!!!!!!

By exhausted in Canton

My 17 yr old daughter received her first Gardasil on April 17,08 with only pain at the injection site on June 16th 08 she received the 2nd within days she started complaining of severe headaches and eye pain so I scheduled a routine eye exam thinking that her glasses may need to be updated. After her exam her optomatrist called me intot he room telling me that she had severe swelling of her optic nerve and scheduled her for an MRI before we could get that done she went to the ER for severe pain in the eye and headaches there they did the MRI and it was normal no tumors or anything that would cause such headaches. On July 3 she called me from work asking to be picked up because the pain was so bad she could not function at all she was weak, dizzy and overall just not feeling good. I took her to the ER again where they performed a spinal tap and tons of bloodwork and admitted her for pain control on July 5th she had a 2nd spinal tap and every day more bloodwork was performed so far ALL tests ran have come back normal. She was in the hospital 5 days. She seen her ophthalmologist a week after being released and we talked to her about the Gardasil and she felt there was enough "coincidence" to have my daughters pediatrician file a adverse reaction form. That has been done and my daughter has learned to live with the pain since nothing seems to help it anymore. Also the last 6 weeks she has had bad insomnia and nose bleeds.

I am a 35 yr old male and have been taking lipitor about 7 yrs. I have a genetically high cholesterol and it has been up to 275. On lipitor its around 175. Over the years I have been on this drug I went from being a normal weight and active to pretty much lethargic and sedentary due to lack of energy and gained ~50 lbs. I couldn't sleep. I got random nausea and fogginess in my brain to the point I could not remember how to perform my job. I usually had minor aches and was bloated. the past year everything has gotten much worse. For a year now, I have been getting large rashes on my body that itch severely and no medications have worked to alleviate them. I found out recently from my doctor that I have a genetic marker in my cholesterol that makes me 3 times as likely to have a heart attack. Its a portion of the cholesterol, i think its called LDL-b or something like that. Anyways, My doctor prescribed zetia to help with my cholesterol since the lipitor wasn't doing it alon. I begin feeling very sick when taking the zetia and after a week or two stopped it. The problems didn't end. As long as I remained on the lipitor, the problems seemed to continue. Its like the zetia released a dam of problems. I stopped the lipitor 4 days ago and have noticed that I feel energy coming back to me and the rash is starting to go away, but I ache severely all over. My shoulders, forearms, and legs are so sore and painful that I can't do anything about this except sleep so I don't feel the pain. I am also very weak feeling and I notice stiffness in my fingers and my grip is very weak compared to how it normally is. I have nausea and stomach cramps and constipation. I feel miserable. I notice its worse in the morning and gets a little better towards the afternoon. I typically took my lipitor in the morning. I do not know if there is a relationship here. Please advise on any help you can provide.

KMJ
07-30-08

Have been taking Zocor for a month. I am about to give it up starting tomorrow. Calling my doctor. I rather try flax seed in my diet. Have had normal cholesterol for life, however the last couple of years it has been hovering around 230-260 esp. since menopause. So, the last check up the doc put me on 20mg, I don't like how I am feeling. Very tired. Low level of energy, and my skin tone appears to be changing yellowish color. Has anyone else experience the dis-coloring of their skin? I am nervous.

I am a 39 year old man with peripheral neuropathy and migraines. When I was diagnosed 3 years ago, the pain in my right leg was horrible and headaches daily. My Dr. put me on Topamax and I was so happy, it seemed to help but one night( about three weeks into it) I went to bed and awoke in the morning legally blind. Topamax was stopped that day but it took 4 months ( and changing the prescription in my glasses 3 times) for my vision to return to 20/20. The doctors tell me I was lucky as some people have perminate lens damage from the optical pressure change.
My doctor said I could not take any thing in that class of medications as it would probably have the same effect on me. So he decided to put me on Cymbalta for the neuropathy. He said it was being tested as a possible use for neuropathy but had not been proven. It works great for the pain and oddly my migraines have gone down to about two a month.

Most of the "side effects" are die off responses (sometimes referred to as a herxheimer response similar to that which occurs when treating syphillis) from bartonella or borrelia. Levaquin is a potent intracellular antibiotic...where these and other organisms can hide. These can be subclinical infections where (at this time) you are not even aware you are infected. If your "side effects" start around the 3rd day into your prescription...rejoice...and suffer for a while, you are killing something really bad.

WOW, I am so happy to find this site. I am a 56 yr old female. I too am on Toprol. I was on 75 mg 2 x's a day for HPB and mitral valve prolapse pain. Then yesterday the Dr. increased my dose to 100 mg 2x's a day .Today my ankles and feet blew up like balloons. I have been having profuse sweating and was cold and clammy for the past year and no Dr could tell me why!! NO sex drive , depression,sleep apnea, severe insomnia, brain fog, short term memory issues, moody, irritable, my husband has threatened to leave me. NO appetite!! Floaters in my eyes started a few months ago, I have so many symptoms that I have read in all your posts. No quality of life for the past year. I have felt like I was losing my mind, gained 35 lbs in past 2 years without changing my eating habits. I gained the weight after I had lost 50 lbs. Been on Toprol about 2 1/2 years ( I think ) Every symptom I have experienced I have read in your posts!! I have type 2 diabetes and am on glucophage, I also take 10 other scripts. I have fibromyalgia and chronic fatigue, RSD in my left arm, muscle pain and joint pain. Pain in my right upper qaudrant. Nausea/ some vomiting, NO ENERGY, Loss of interest in most of life. So now after reading all your posts I have to ask myself, are all my symptoms linked to the Toprol and not syndromes or illnesses? I am calling my doctor in the morning and getting off this med!! They will just have to put me on something else!!!
So how do I post to receive replies?
Joyce47oh

I`ve been on Simvasatin for years- 10 mg. Secrist at ctcn.net The last 2 months blured vision, nausea, numb foot, hands & chin, burning feeling in legs & bladder. stopped the medicine about 4 days ago, will it ever get back to normal? Arlene

I'm 17 and I took Levaquin back in November and still have to use a wheelchair to get around. I ended up having to go to the Mayo clinic because there were so many factors to my case, and we were not getting anywhere with my doctors at children's hospital. i also have mono and west nile virus and so all that viral activity made the reaction so much worse. They discovered Levaquin caused severe tendinitis in each and every tendon, but my hips mainly affected causing them to be extremely fluid-filled. I also have a permanent peripheral neuropathy from it. They discovered an autonomic syndrome called POTS (postural orthostatic tachycardia syndrome) , however that can logically be attributed to either the mono or the reaction.
I go to physical therapy every week now for my hips and my ability to be ambulating well enough to go to college in 6 months is being questioned.

2 yrs ago I was diagnosed with peripheral neuropathy. I have been on Topamax since, because of the severe pain it causes. I have never experienced weight loss and I was on up to 400mg a night. I am now on 200mg a night. My tastes are fine and my drinking sodas were never like metal. But for the fatigue of the disease I also take Provigil in the morning. I have noticed my eyes have changed. Never gave it a thought to be Topamax. Plus I just got new glasses again 3 months ago and am seeing a change in my sight again. Also there is a noise in my ears,not ringing,but sounds like crickets. Never had that before. I was on 2 other meds but I took myself off of them because I really don't like taking so many. The others had worse side effects. Until they find a cure for this disease it looks like I'm stuck with Topamax. This is one pain I will not and can not live with.

This is a total nightmare and i need advice! I was on Lamictal for a year and about six months into my health began to slowly deteriorate. It started with shortness of breath and heart palpitations and eventually attacked every system of my body. My symptoms are muscle pain, spasms and knots to the point that i can't turn my neck sometimes, joint pain (mostly knees), stabbing floating pain everywhere, headaches, frightening tingling in my extremities and a few times my entire body, sore throat, flu-like feelings, stomach cramps, bloating and heartburn. The list goes on. I have been off of it now for two weeks. My psychiatrist has never seen this type of reaction before and is not convinced it is the Lamictal. I have been to every single type of doctor and the ER twice, had extensive lab work, CT scan and two MRIs. I have been off Lamictal now for two weeks and am not feeling much relief. I am so scared and frustrated and please need advice. Has anyone else experienced this? Does it ever go away? I feel like I am literally living a nightmare with no-one to turn to for advice because no-one seems to know ANYTHING!!!!

I was put on Levaquin for 21 days to treat chronic sinusitis and I am only 17 years old. After about the 3rd day I was having great pain in my hips and knees and we called the doctors office to say we were having some of the side effects you're supposed to notify your doctor for, and they told me to keep taking it because all medicines have side effects and not to freak out. By the fifth day I had to be rushed to the ER because of serum sickness and i finally stopped it. Now, 2 and half months later, I still walk like a 95 year old and have to use a wheelchair to get around. I've also developed hypersensitivity to cold and touch and my limbs go numb randomly.

I have pain in my left hip flexor when taking Lipitor. I was on 40mg/day and went on a daily walk with my wife after her back surgery. My left hip flexor would cramp. Sometimes it would cramp so bad, I had to quit walking and catch a ride home.

I had a month holiday off of Lipitor and could run after a week with no pain.

I started back on 10mg/day and the pain has returned, but not as bad.

I did an experiment- Laying flat on my back, I could lift my left leg one foot off of the floor. I stopped the Lipitor for seven days and could lift my left leg two feet off of the floor.
Can anyone help me?

I have just been reading the list of, what I am considering to be "possible", side effects from Dilantin . Doesn't everyone, whether on Dilantin or no drugs at all experience headaches, nausea, stomach pains or depression from time to time?
After being on this medication for over 30 years there are some things which I've experienced. Just about everyone complains of hyperplasia but it has been my experience that if I maintain a clean healthy mouth, there is no hyperplasia. If, for one day, I do not brush my teeth, hyperplasia sets in immediately & it then takes a week or so to get it under control. So, brush, brush & brush your teeth.
As far as memory loss or difficulty learning, I suppose it happens to everyone at one time or another. However I have graduared from high school with honours & became a registered nurse (top 5 in my class of 56) all while I was on Dilantin.
The only true adverse side effect from taking Dilantin for over 30 years which I experience is that whenever I am tired, my speech can easily slur. I am very aware of this & it's become habit to pay close attention to my pronounciation & correct it so I may articulate normally. Not a big deal & a very small price to pay.
I'm not one for pity trips or blaming my seizures or medications for my downfalls in life. I am so grateful to have my seizures under control & hate to think where I would be today if not for Dilatin. Remember, if you look for it , you will likely find it. So try not to look for all these adverse side effects (crutches)& see the benifits. We have enough to handle keeping this under control & educating the sometimes ignorant world.
I took control of the epilepsy that attacked my system. I would never allow it to control me. Good luck to all of you. Sincerely :)

I am a physician and have prescribed levaquin to many people. I have had some of them complain of what they thought were serious and variable side effects but mostly I attributed their problems to anxiety and hypochondiasis. I now know differently. I took levaquin, and for over a year I have had serious CNS anxiety, insomnia, joint and tendon pain, and widespread peripheral neuropathy. It has been an awful time and since realizing that the effects are often long term I have been able to identify many other patients who have developed serious long term problems with anxiety, depression, arthropathy and tendonopathy, neuropathy and possibly endocrine effects like gonadal failure and worsening of diabetes. There are no long term studies done post marketing to identify these effects and to unify all of these problems into one syndrom of fluoroquinolone toxicity. This is a big problem and I believe thousands of patients have been adversely affected by the use and misuse of levaquin and probably the other fluoroquinolone antibiotics. I have other colleagues who are beginning to recognize the long term consequences of levaquin and the fluoroquinolones. More research and study needs to be done. In the mean time I am sure that Johnson and Johnson, Ortho- Mcneil, will continue to refute that the incidence of serious adverse reactions is much higher than they report.

Lipitor reduced my Cholesterol from 280 to 140. But... after only 4 months on the drug I developed pain in my legs. After several visits to the doctor I was told to get off the drug. One month later my health had deteriorated to the point that I could hardly walk. After another doctors visit and many tests I was diagnosed with peripheral neuropathy with the symptoms of leg pain, muscle loss and nerve damage in both legs, feet and hands. Also numbness in both hands and feet. Inability to move any of my toes. Liver damage. Of course with the problems with my feet I have poor balance. Additionally I have memory loss. Because of the neuropathy I can not get health insurance without paying a much higher preminum than normal. I am taking Gabapentin 1200 ml 3x day.

My condition has improved gradually but I still have the P. Neuropathy and there is no cure for it. My balance remains poor and the numbness, pain, nerve and muscle damage remain.

This diagnois is from a family doctor as well as a neourologist.

My recommendation is stay away from the statins.

I have been on lipitor for a little over two years now. I experience extreme joint and muscle discomfort. I am also picking up weight at an alarming rate. No matter what I do to lose the weight, it's not working. I've had several blood tests, but all come back fine..but I know I don't feel well and I'm having trouble remembering things....