Pharmaceuticals symptoms and conditions

UPDATE from Calybo ! ! ! ! !!!!!!!
The post below this (or a couple below ) is one that I added to this site almost a year ago!
After having Mirena removed in OCT. 08' it has been a very long uphill battle reclaiming my health. I feel I am now 90% better. I still experience some of the symptoms - just much, much,much milder than they were at first. I feel like Mirena has taken nearly a year away from my life! I've had to focus so hard on my health that I feel everything else has been put on hold. I just feel so disappointed in conventional medicine and pharmaceuticals for allowing this to be sold to women without doing more studies and not adding more warnings on adverse affects. it wasn't until I went to see a holistic doctor that I really started to make progress.

Hey there! I have been on Venlafaxine/Effexor for 5 months now and have steadily had my dosage increased (I now take 150mg in the morning and 75mg at night) and I can say that out of all the other antidepressants that I've taken (Prozac, citalopram, sertraline) this is the one for me. Yes I did have some side effects such as slight nausea in the beginning but the one that gets me is sweating, and I mean I sweat a lot! But for me it is worth it so I am not an irritable, bed ridden depressive and I actually want to go out and enjoy life with my son. Effexor is the best medication I have come across for relieving the crushing anxiety that I felt in my chest and has really helped with OCD symptoms.

It has taken me 3 years to come across this medication after numerous fails with the other meds, which in turn (on each occasion) made me doubt pharmaceuticals and my doctor, but if you are suffering on this drug then change it, there are so many slight variations to anti-depressants the one for you is out there, don't suffer in silence, just be brave and keep trying because when you find the one your quality of life will be unbelievably better.

Much love and strength to you all

Wow, who should I believe? Placebo controlled studies which suggest Avelox is a perfectly safe drug or a bunch of crazy people who like to TYPE every OTHER word IN all CAPS who are probably all middle aged women with psychological problems and/or fibromyalgia, irritable bowel syndrome, or other made up diagnoses.

Here's a hint morons: The reason why every drug in existence now lists every possible side effect is because of crazies like you. This way, the drug company can protect themselves from litigious idiots like the poster below who wants to join a class action lawsuit. This only compounds the problem, though, because then more crazies look at the side effect profile and when they see that "Oh my gosh, it says right here it causes x, y, and z" it just validates in there mind that this is somehow a dangerous drug.

I swear, if all of the pampered babies in this country were put to work in a rice field in Cambodia, there would be a lot less nonsense in the world. You would see what true pain and suffering is about.

My fiance is 27 years old and she has Mirena for about 5 months now. She had her son about 10 years ago so I don't think any of her symptoms are postpartum related. The thing I noticed most after she's had Mirena done is that she's always tired and taking naps whenever possible. She's also had tons of acne issues since she's been on Mirena. The thing that I don't like the most about the side effects is that she claims shes always "out of it" and "zoned out". She even complains that she has anxiety attacks too, where she gets pain in her chest.

A friend of ours recommended her to use some estrogen control herbal pills and that's helped her acne and her mood a lot. But I mean, she shouldn't have to take any pills to "counteract" the side effects. I guess the thing I'm upset about is that THE DOCTOR NEVER WARNED HER ABOUT ANY OF THESE SIDE EFFECTS. I personally, don't trust doctors 100% and I'd be naive to think that all doctors are advising for just your benefit. There are doctors out there for sure that have financial / relationship gains with pharmaceuticals for prescribing certain brand drugs. I'd be very vary especially for the people who wrote here saying their doctor INSISTED they kept Mirena. Something not right there...

headache,nauseous,leg cramps, pain in my left breast, around heart...now, around each period my breasts hurt, and i have terrible stomach ache, like cramps, which i never had before..i also started having acne on my back and shoulders...but the worst thing is, my room-mate, she was using Yasmin for 9months, died a week ago. she wasn't sick at all.she actually did have a few headaches, and weird stomach ache, but we didn't seem to connect the two...

i have been on prednisone for 5 years off and on and he moon face is there the hair loss the weight i really want to come off it so bad the asthma is a big issue in my life i wish they would come out with a better drug for us asthma patients the withdrawals i have been going through are the hair loss i use to have long thick beautiful hair thin face smaller body i am hoping some day i will get it all back
hopeful

Hey, maybe those ancient people who invented yoga were on to something when they say to do "your o-o-h-h-m-m-s-s-." So hum those ohms every day and increase our resistance against nasal infection.

American Journal of Respiratory and Critical Care Medicine Vol 166. pp. 144-145, (2002)
© 2002 American Thoracic Society

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Brief Communication

Humming Greatly Increases Nasal Nitric Oxide
Eddie Weitzberg and Jon O. N. Lundberg
Department of Anesthesiology and Intensive Care, Karolinska Hospital, and Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden

Correspondence and requests for reprints should be addressed to Dr. E. Weitzberg, Department of Anesthesiology and Intensive Care, Karolinska Hospital, S-171 76 Stockholm, Sweden. E-mail: ******

The paranasal sinuses are major producers of nitric oxide (NO). We hypothesized that oscillating airflow produced by humming would enhance sinus ventilation and thereby increase nasal NO levels. Ten healthy subjects took part in the study. Nasal NO was measured with a chemiluminescence technique during humming and quiet single-breath exhalations at a fixed flow rate. NO increased 15-fold during humming compared with quiet exhalation. In a two-compartment model of the nose and sinus, oscillating airflow caused a dramatic increase in gas exchange between the cavities. Obstruction of the sinus ostium is a central event in the pathogenesis of sinusitis. Nasal NO measurements during humming may be a useful noninvasive test of sinus NO production and ostial patency. In addition, any therapeutic effects of the improved sinus ventilation caused by humming should be investigated.

Key Words: exhaled • sinus • sinusitis

A series of articles published by the Boston Globe in 2001 revealed

that the number of children enrolled in clinical trials in 1997 was

16,000: by 2001, the number reached 45,000. The Globe found that children

enrolled in clinical trials had suffered and died, and that ethical

standards had been violated.

Financial incentives for parents, physicians, and researchers had undermined

children's welfare. Children are currently being recruited with Toys

'R Us gift certificates. Parents in need of money are offered as much

as $1,000 to "volunteer" their children for drug experiments that involve

risks of harm. The physicians

who are engaged in such coercion receive as much as $5,000 in kickbacks

(euphemistically called, "referral fees") for the recruitment of children.

None of these disturbing facts were brought to the attention of the

U.S. Congress when it passed the Best Pharmaceuticals for Children Act

in 2002. The evidence, however, shows that children are being deprived

of existing, more protective federal regulations under 45 CFR 46, Subpart

D, and are being subjected to foreseeable risks of harm and discomfort,

often on the basis of a presumed potential risk for which there is no

empirical evidence. The FDA

acknowledged that before FDAMA the use of children as subjects in phase

I safety drug studies "had been primarily limited to life threatening

diseases and children who had the disease" in question.

The policy prior to FDAMA protected children from harmful experiments

in accord with the 1983 federal regulations (45 CFR 46.404-409). Following

passage of FDAMA, however, federal policy broadened the criteria for

inclusion of children in research generally and for participation of

children entered in high-risk experiments. In 1999 the FDA acknowledged

that the post-FDAMA policy change "led to an increasing number of proposals

for studies of safety and pharmacokinetics, including those in children

who do not have the condition for which the drug is intended."[64

The following article in the WSJ may explain the reason for the significant number of Adverse Reactions to statin drugs.

Why You Can't Tell Where
Your Medication Was Made
April 8, 2008; Page D1- Wall Street Journal
Bananas come with those little stickers listing their country of origin. Why not pharmaceuticals?
That's what some consumers -- and even some physicians -- are asking since the Food and Drug Administration linked the deaths of 19 people to contaminated batches of the blood thinner heparin from China.
*******

I encourage every patient with a bad experience taking statins to contact the FDA (see, July 1, 2008 posting for FDA contact info).

The following article in the WSJ may explain the reason for the significant number of Adverse Reactions to statin drugs.

Why You Can't Tell Where
Your Medication Was Made
April 8, 2008; Page D1- Wall Street Journal
Bananas come with those little stickers listing their country of origin. Why not pharmaceuticals?
That's what some consumers -- and even some physicians -- are asking since the Food and Drug Administration linked the deaths of 19 people to contaminated batches of the blood thinner heparin from China.
******

I encourage every patient with a bad experience taking statins to contact the FDA (see, June 29, 2008 posting for FDA contact info).

i heard something on the television about a lawsuit involving advair and came across this site looking for information. i have been on advair for aprox 8 years. when i read some of these comments i began to cry. it so said exately what i have been feeling right down to being diagnosed with rhumetoid arthritis and fibro. i spent 6 hours in the er last week with a heart rate of 112. i went to my doctor as recommended after my visit and he blew me off because he was mad i went to the er and told me to go see a surgeon to cut into my collar bone, go down to my lungs and biopsy them. i see a different doctor next Thursday for a second opinion. i am so tired of being sick and to think, it could all be from this one thing. i am going to talk to the doctor about this on Thursday.

Hopefully this will prove to the doubters that there are genetic reasons for the variation of efficacy and adverse side effective when taking Montelukast.

I have several areas of concern (concerned citizen is concerned). One of the main areas is the reliability of Montelukast due to differences in genetics among populations. The cysLT1 (Singulair) receptor is a GENE. As I said before, it would be possible to predict those patients for which Montelukast would and would not be effective and those patients whose gene expression profile would cause them to have unwanted side effectives.

I have been looking for a way to give reasonable proof of that which could be used to convince your doctors that Montelukast is not for everybody. I happened to locate a researcher who had invented and patented methods for predicting drug sensitivity and efficacy in inflammatory disease. I have quoted below from his patent application. He intended to provide a method for determining efficacy and drug sensitivity for pharmaceuticals which include leukotriene antagonists - Montelukast.

Quoted from:

Methods for predicting drug sensitivity in patients afflicted with an inflammatory disease
US Patent Issued on December 12, 2006

Methods are disclosed for predicting the efficacy of a drug for treating an inflammatory disease in a human patient, including: obtaining a sample of cells from the patient; obtaining a gene expression profile of the sample in the absence and presence of in vitro modulation of the cells with specific cytokines and/or mediators; and comparing the gene expression profile of the sample with a reference gene expression profile, wherein similarities between the sample expression profile and the reference expression profile predicts the efficacy of the drug for treating the inflammatory disease in the patient.

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The field of pharmacogenomics measures differences in the effect of medications that are caused by genetic variations. Such differences are manifested by differences in the therapeutic effects or adverse events of drugs. For most drugs, the genetic variations that potentially characterize drug-responsive patients from non-responders remain unknown.
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In another embodiment, the invention is directed to a method for predicting the efficacy in a human asthma patient of leukotriene antagonists including, but not limited to, montelukast (a.k.a., SINGULAIR™; Merck, Whitehouse Station, N.J.), zafirlukast (a.k.a., ACCOLATE™, AstraZeneca, Wilmington, Del.), and zileuton (a.k.a., ZYFLO™; Abbott Laboratories, Chicago, Ill.), comprising: obtaining a sample of cells from the patient; obtaining a gene expression profile from the sample in the absence and presence of in vitro modulation of the cells with specific mediators; and comparing the gene expression profile of the sample with a reference gene expression profile, wherein similarity in expression profiles between the sample and reference profiles predicts the efficacy in the human asthmatic patient of leukotriene antagonists.

Many of the cells involved in causing airway inflammation are known to produce signaling molecules within the body called "leukotrienes." Leukotrienes are responsible for causing the contraction of the airway smooth muscle, increasing leakage of fluid from blood vessels in the lung, and further promoting inflammation by attracting other inflammatory cells into the airways. Oral anti-leukotriene medications have been introduced to fight the inflammatory response typical of allergic disease. These drugs are used in the treatment of chronic asthma. Recent data demonstrates that prescribed anti-leukotriene medications can be beneficial for many patients with asthma, however, a significant number of patients do not respond to anti-leukotriene drugs.

--------------------------------------------------

The genes selected are those that have been determined to be differentially expressed in either a disease, drug-responsiveness, or drug-sensitive cell relative to a normal cell and confer power to predict the response to the drug. By comparing tissue samples from patients with these reference expression profiles, the patient's susceptibility to a particular disease, drug-responsiveness, or drug-resistance can be determined.

http://www.patentstorm.us/patents/7148008-description.html

The inventor's website: Hakon Hakonarson M.D. The Children's Hospital of Philadelphia

http://stokes.chop.edu/research/profiles/?ID=251

I have been on Advair for the past three years after a severe asthma attack on Oct 2005....what a mistake..I got all the side effects possible...really! Rash, arrhythmia, tachycardia, eye problems, runny nose, shakines, depression, anxiety, sleeping problems, nausea, muscle cramps or muscle spasms, hoarseness or voice changes, sinus infections, abdominal pain, dizziness, etc, etc and it is gatting worse! I am on 100/50 once...every two days! I could not stand all of this anymore- Does anyone know about some other less dangerous medication (Albuterol gives me the worse arrhythmia) Is it sensible to note that Advair and another dangerous medication; Paxil are from the same maker: glaxosmithkline pharmaceuticals? No wonder! Any input/help will be most welcome-A very worry French guy in San Francisco-

I went back to my PCP today. Yes the one that gave me the Levaquin. He was very nice and even agreed it was the Levaquin I took back in December. He said that these types of side effects we all are describing are RARE (I would have kicked him for all of us, but my legs hurt to bad).

But he did acknowledge pain and my symptoms (listed in my December post) and prescribed me Prednisone for my ligaments and Lyrica for my nerve pain. He also said it was going to be a long haul. I know that some of you are dying to telling why these meds are bad too, but I am going to try it because I haven't really been out of my bed for two weeks.

I just wanted to let you all know, that maybe some doctors are starting to listen... and that we should keep speaking out and warning others about the HIGH risk of our side effects.

I no longer take Imitrex as it makes my migraines 100x worse, more frequent; but I was reading following side affects everyone has.... Ive dealt with the queasiness, feeling lethargic and such....

But some of the ones not listed that I had was extreme abdominal and stomach cramping where I was in fetal position (i kid you not), my back felt as if i had a warm heating pad to it (kind of a benefit on cold days!) and from the calves down, I felt as if I were walking around with 25 pound weights on both legs; I felt very weak and could barely move.

Anybody ever experience any of this!? :(

Hi, I just put the NuvaRing in about 2 weeks ago and so far I'm not exactly impressed. It's nothing real BAD but it has completely changed the dynamics of my vagina. It is dry, with a stinging feeling inside all the time - after sex is way worse, and my vagina gets so sensitive that it throbs and aches on the outside, and stings on the inside.

I thought "ok, give it a chance to adapt" but really, there is a foreign object in my body which is

A) unhygienic - it will catch all sorts that will sit in there and fester - lots of semen. The self cleansing action of the vagina (it sheds its walls very quickly, and is full of mucous membranes) is hindered. And
B) I can feel it inside, but not like you would feel a 'foreign object'. I can feel it as it an almost painful uncomfortable achy feeling that is like almost a cramp. Hormones leaching into my flesh - very unnatural I have to say.

What The Man Thinks
Last night whilst having sex, my partner came, and I moved slightly and he gasped with pain and said "I thought that felt a bit strange" - the NuvaRing had hurt his penis but he didn't realize until afterwards as it had directly and intensely stimulated him, it was only afterwards that he realized it was verging on very painful. Not good.

He can also feel it when we have sex and finds it a bit off putting - he is also having sex with the NuvaRing, not just me.

In my opinion, I'm really glad that people are thinking of new ways to administer birth control, but I don't think this one is a winner. I hate condoms with a vengeance but you know what? They get more and more appealing every stinging day.

Don't forget ladies that the greatest experiment ever performed on women was the big fat bullshit regarding oestrogen. We have been experimented on for 50 years, yet right at the beginning scientists knew that oestrogen caused cancer in rats and mice, AND WOMEN. Don't ever forget that pharmaceuticals are out to get your dollars, and will fudge results, fire people, ruin lives and make you sick. Next time you have something wrong with you, try going to naturopath for a proper solution - they actually know what is going on with your body and don't prescribe a ''one size fits all' drug answer.

That's it for me and the NuvaRing!
I tried. I failed.
: )

I have started Lamictal and I have numbness on the right side of my face.

Since posting my side effects with the Mirena a lil' while ago! I've read all of Oct. 07 entries of side effects and I am realizing that i have more... I am dealing with a strange discharge, heavier hair loss (since I was already having it postpartum), weight gain & bloating, and a downward spiral on my already improved postpartum depression.
I will be having this THING removed tomorrow... I already spoke to my Dr. over the weekend, who told me that I was obviously having a severe reaction to the chemicals in the Mirena... I feel like my skin is going to come off! If i don't scratch it off, first!!!
I feel there's a MAJOR Big Pharm/Medical Industry cover up going on... And not just with the Mirena, but with Most MEDS... EVERYBODY, Beware of PHARMACEUTICALS...!!!
Sylvia

I am currently on Levaquin because Bactrim did not completely relieve me of a UTI infection. I avoid taking pharmaceuticals at all because I suffered chemical poisoning from living near the World Trade Center and, as far as I'm concerned, ALL pharmaceuticals are poison...but necessary in some cases when diet and exercise are not enough to stay healthy. I have some minor side effects and the infection seems to be clearing. Before I started taking it I looked at this website. I just have to say that I can't believe the number of people who are depending on their doctors and pharmacists or leaflets to give them information. It is YOUR health and YOUR responsibility. Personally, I would never put something into my body without finding out myself and researching it. If someone chooses to not take responsibility for their own body and health, then don't blame your doctor for that. It is your choice to put your health in someone else's hands...and the fault is your own. Don't put your health in the hands of someone other than yourself without doing the research.

I just started taking Warfarin on December 11, 2006 due to blood clots from surgery. My protime numbers won't go over 2.0, so I'm taking 12 mg and will probably start Lovenox injections. All my life I have rejected taking pharmaceuticals of any kind, and now this. I've told my doctor to get me off these meds asap, but now I have to see a hemotologist. If he says warfarin for life, I'll tell him no thank you. I will not live the rest of my life poisoned. As for side effects, the only thing I've noticed is a fitful night's sleep. I really haven't been that tired. I do get achy, but figure that's from physical therapy from surgery.

I am so glad I have come across this website, my son recently was put on singulair 4mg for allergies, but we have definately noticed a very negative, aggressive attitude from our child who is 4 yrs. old. I looked on the makers website and it does not say anything about temperment change, aggression or anything of that nature. I will take him off immediately after reading everyone on this website's testimonies. I am also greatful for you mom's etc. out there sharing your experiences. FYI for Annabelle, I have worked in the past around pharmaceuticals, and yes DR's do get kickbacks in the form of vacations, etc. It's just not talked about openly nor openly admitted to. Terri

To redaurora:
I am completely angered by your story!! I can't believe that an OBGYN would be so ignorant to think Yasmin didn't play a role in your mild stroke when it's one of the risks listed RIGHT ON THE PACKAGE. Honestly, it seems like we all have to do our own research on these things... it's the only way we can get trusted information (which I have thankfully gained from all the women on this site).
I did some research and found that doctors claim their number one source for information on side effects are the pharmaceutical companies themselves (like they are going to admit there's a problem). Also, I have a friend involved in marketing pharmaceuticals and you wouldn't believe what kind of perks docs get from drug reps! (conflict of interest??)
It really makes you wonder....good luck with your recovery from yasmin. I am 4 months off Yasmin as well and still suffering...

Before anyone goes on another synthetic drug to balance out the side effects of Yasmin, you might want to consider herbal options. I'm trying vitamin B6 and St. John's wort for depression, kelp for thyroid balance, and parsley tea to bring on my periods when they're supposed to come. Taking herbal medicines should be done with careful consideration just like pharmaceuticals (sp?) but maybe a little less risky. If anyone else has tried this route to de-tox, please share your experiences!

After reading all the posts, it is becoming clearer to me Lipitor is a poison. I started Lipitor a year ago after heart surgery. Now, a year later, instead of feeling better, I feel worse than before surgery. My whole body aches. I take 40mg. a day of Lipitor. Not any more. I am stopping the drug and replacing it with alternative herbs and suppliments. What is the point of having a very low cholesterol and not feeling better because of side effects. The pharmaceuticals and the doctors are all in bed together. We, are the results of this on this board. A lot of trusting, good people who are being gradually killed. I am over it. No more drugs for me. I am taking charge of my life now. Right, or wrong.