Potassium levels symptoms and conditions

I am 38 years old and was on Yasmin for 3 years to control ovarian cysts that kept bursting. It kept good control of my acne, but I had no sex drive, horrible facial hair, no vaginal lubrication, and extreme pain during sex especially climax. Finally, 2.5 years ago, I suffered from right-side paralysis which ended up sending me to the hospital. My potassium levels were so low that my I was suffering from neuorlogical problems that they initially thought I was having a stroke at the hospital. Taking potassium did not keep my potassium levels up while still taking Yasmin, so I finally went off it. The literature does mention that one may suffer from low potassium, but even taking supplements did not allow me to keep my potassium levels up enough. I am getting an IUD put in place on Thursday and hopefully this will take its place well enough!

Yaz increases your potassium levels, SO DO NOT eat anything with Potassium or take any medications that will increase your potassium. You will over load your system and make it even worse on you. You really need to read the enclosed brochure that came with Yaz from front to back to ensure you are fully aware of what you are taking and all the risks and side effects you will get. I had the same issues with my calves and it was not normal at all. Since I have stopped taking Yaz all my symptoms are gone and physically I feel normal again. I have not gotten my period yet, which I thought would come when I stopped taking Yaz, but nothing yet. I experienced anxiety attacks whenever I tried to climax so I understand what you are talking about. Yaz lowers your testosterone levels which drives your sex lfe, so there may be no hope for it to be normal again as long as you are on Yaz.

Am in my second month of taking Metoprolol to control atrial fibrillation. Have been increasingly dealing with disturbingly vivid dream, headaches, slight nausea, abdominal discomfort and overall achiness. What is an alternative med to treat atrial fibrillation? I have glaucoma and a cardiac pacemaker for complete heart block. All suggestions welcomed. I'd like to dump the Metroprolol but appreciate that since starting to take it, I've had no problems with fibrillation (which my pacemaker isn't designed to control).

I'm 22 years old and I have been on Yasmin for 3 years. The first year it was fine, but the next year I began getting panic attacks which I never even believed in until I had one myself. I've had severe anxiety that is uncontrollable and doesn't allow me to sleep at night. Let's not even talk about the emotional mood swings during my period. My boyfriend knows when it's that time of the month because I'm not myself. I will cry over things that would never make me cry in a million years. I'm mean and moody and then 20 minutes later I feel bad, but then I'm crabby again. Weight gain has not been a problem for me only about 3-5 pounds, but my breasts did go from a large B to a D. My boobs definitely do not fit my body. I have noticed a lot of hair fall but I just thought it was normal. I too have had problems with my potassium levels as I would get leg cramps in the middle of the night so I began drinking Gatorade and eating bananas every morning which has helped. I love being on birth control because it helps me plan accordingly, but I just don't feel like myself anymore. I am always hungry and am never full. I literally have to tell myself out loud that I'm done eating because it doesn't trigger for me. I have had a stomach ache nearly everyday of being on the pill. I became addicted to TUMS which only made it worse. I thought it was stress related which it might be, but I literally do not go to the bathroom for 4 or 5 days and it is soooo painful. Another thing is that I have no sex drive. I really have to prepare myself for it otherwise sex does not even occur to me. My boyfriend thinks I'm not attracted to him, but I AM! We just moved in together and you would think it was "freedom" but I'm just motivated to have sex. This is not normal for a 22 year old healthy female with an extremely hot man.

Anyway, I just went to the doctor and told her I was interested in Yaz. She gave me a few sample packs which I will begin next week. I'm hoping for the best and I truly do believe that birth control is a trial and error process. Everyone's bodies are different and you need to find the one that works best for you! I will write again once I know how Yaz works out.

-MCL

Two acting effects in Yasmin are:
ANTI-MINERALOCORTOID (Diasperonone)
and
ANTI-ANDROGENS (Spironolactone)

MINERALOCORTOID
(Yasmin has ANTI-mineralocortoid function/effects):
-----------
Mineralocorticoids are a class of steroid hormones characterised by their similarity to aldosterone and their influence on salt and water balance. (note Yasmin has diasperonone as an acting ingredient which acts as a potassium sparing diuretic.)

The primary endogenous mineralocorticoid is aldosterone. Yasmin has anti-aldosterone properties.

Aldosterone acts on the kidneys to provide active reabsorption of sodium and an an associated passive reabsorption of water, as well as the active secretion of potassium.
Note: Yasmin has diasperonone that is a potassium sparing diuretic. This in turn results in an increase of BLOOD PRESSURE and BLOOD VOLUME.

Aldosterone is produced in the cortex of the adrenal gland its secretion is mediated principally by angiotensin II, but also by ACTH (adrenocoritotrophic hormone) and local potassium levels.

Hyperaldosteronism (the symtpom caused by elevated aldosterone) often shows up as:
-------------------
1. Hypertension-high blood pressure. High blood pressure that is arterial in nature gives a higher risk of heart attack or stroke than any other disease. Persistent hypertension/high blood pressure is one of the risk factors for strokes, heart attacks, heart failure and arterial aneurysm, and is a leading cause of chronic renal failure (which means chronic kidney failure)

2. Accelerated excretion of potassium ions. With extreme K+ loss (note Yasmin has potassium sparing diuretic), there is muscle weakness and eventually paralysis

Underproduction, or Hypoaldosteronism:
-----------------------------
leads to the salt wasting state associated with ADDISON'S DISEASE (also known as chronic adrenal insufficiency or hypocortisolism):
is a rare endocrine disorder in the body produces insufficient amounts of adrenal steroid hormones (glucocorticoids and mineralocorticoids) (note Yasmin has anti-mineralocorticoid effect)-it is essentially the inability of the Adrenal Gland to produce adquate amounts of CORTISOL in response to stress. This is an Endocrine discorder caused by high levels of cortisol in the blood. Cortisol is released from the adrenal gland in response to ACTH being released from the pituitary gland in the brain. Or..

HYPOADRENIA/ADRENAL FATIGUE:
-----------------------------------
The adrenal glands are part of the body's mechanism for short term stress response and management. (Note Yasmin's effect on adrenal glands). They are involved in the production of the hormone adrenaline (also known as EPINEPHRINE **-the famous fight or flight chemical released in stressful situations which increases the body's metabolic energy regulation and control system-and thus control to an extent the energy available to body systems.

Theorized by alternative medical practictionerS that under conditions of long term stress, the adrenal glands can become less responsive to circumstance and cease to function optimally leading to a wide* but slightly vauge range of FATIGUE AND STRESS RELATED CONDITIONS including a greater likelihood of psychological conditions such as depression and possibly certain other mood disorders.

SYMPTOMS OF ADRENAL FATIGUE:
------------------------------------------------------
1) DEPLETION OF ENERGY
2) LOSS OF RESILIENCE
3) FATIGUE
4) NERVOUSNESS
5) ANXIETY
6) EXACERBATED PMS
7) DEPRESSION
8) BRAIN FOG
9) CARBOHYDRATE CRAVINGS
10) ALLERGIES
11) MUSCULAR PAIN
12) JOINT PAIN
13) IRRITABLE BOWEL SYNDROME

CORTICOSTEROIDS:
(Yasmin's ingredients contain anti-mineralocortoid)
----------------------------------------------
Additionally, the corticosteroids functions, produced in the adrenal cortex include that of stress response, immune response, regulation of inflammation*, carbohydrate metabolism, protein catabolism, blood electrolyte levels and behavior.

Yasmin's listing of possible side effects include trouble with:
-colds and flu
-"nervousness"-not "anxiety" but "nervousness" -insulin resistance (which is carbohydrate/sugar intolerance),

Yasmin's ANTI-ANDROGEN is Spironolactone:
Synthetic steroid which is commonly used as a diuretic or as an Anti-androgen. Potassium sparing diuretic.
-------------------
This on its own is a weak diuretic. Due to its anti-androgenic effect, it is common component in hormone therapy for male-to-female Transsexual and transgendered people and is also used for treating hair loss and acne in women.

Spironolactone inhibits the effects of aldosterone by competing for intracelluar aldosterone receptor. This increases the secretion of water and sodium, while decreasing the excretion of potassium. Spironolactone has a fairly slow onset of action, taking several days to develop and similarly the effect diminishes slowly.

ADVERSE REACTIONS TO SPIRONOLACTONE:
---------------------------------------
-menstrual irregularities and testicular atrophy
-ataxia-muscle weakness/atrophy
-erectile dysfunction
-drowsiness
and rashes*.
A carcinogenic effect has been demonstrated in rats. Carcinogen is a term that refers to any substance or radiation which is an agent directly involved in the promotion of cancer or in faciliation of its propagation.

ATAXIA:
-------------
Steady and clumsy motion of the limbs or torso due to failure of the gross coordination of muscle movements. This often occurs when parts of the nervous system that control movement are damaged. People with ataxia experience a failure of muscle control in their arms and legs.

Androgens are the precursor of all estrogens (the female sex hormones). the primary and most well known androgen is testosterone.

A subset of androgens, called adrenal androgens, includes any of 19-carbon steroids synthesized by the adrenal cortex, the outer portion of the adrenal gland that function as weak steroids or steroid precursors, including DHEA (dehydroepiandrosterone), DHEA-S (dehydroepiandrosterone), and androstenedione. Because Yasmin's ingredients have an anti-androgen effect that effect our adrenal glands-women with adrenal problems are advised not to take it.

Besides testesterone (which is responsible for sexual libido/function), other androgens include:

1) DHEA
(dehydroepiandrosterone: -a steroid hormone produced from cholesterol in the adrenal cortex which is the primary precursor of natural estrogens.

2) Androstenedione (Andro)-
an androgenic steroid, which is produced in the testes, adrenal cortex and ovaries*. While androstenediones are converted metabolically to testosterone and other androgens, they are also the parent structure of estrone. Estrone is an estrogenic hormone secreted by our ovaries. It is one of three estrogens which also include estriol and estradiol. Estrone is the least prevalent of the three hormones, estradiol being prevalent almost always in the female body, estriol being prevalent primarily during pregnancy.

3) Androstenediol:
the steroid metabolite that is thought to act as the main regulator of gonadotropin secretion-protein hormones secreted by gonadotrope cells of the pituitary gland. The two principle gonadotropins are LUTENIZING HORMONE (LH) and FOLLICLE STIMULATING HORMONE (FSH)-both of these are what are naturally release by our bodies on a monthly cycle are part of natural menstruation. The third human gonadotropin is human chorionic gonadotropin (hCG) produced by our placentas during pregnancy.

4) Androsterone:
a chemical by-product created during the breakdown of of androgens-or derived from progesterone -that also exerts minor masculnizsing effects, but with one seventh the intensity of testesterone.

5) DHT Dihydrotestosterone-
a metabolite of testosterone that is actually a more potent androgen in that it binds more strongly to androgen receptors.

FUNCTIONS OF ANDROGENS:
(keep in mind Yasmin has anti-androgenic properties):

Muscle mass:
Androgens promote the enlargement of skeletal muscle cells and probably act in a coordinated manner to enhance muscle function.

BRAIN:
Circulating levels of androgens can influence human behavior because some neurons are sensitive to steroid hormones. Androgen levels have been implicated in the regulation of human AGGRESSION and LIBIDO.
Note, Yasmin's ingredients have anti-androgenic effects. That means essentially translates as suppressing the effects that androgen has in our bodies to regulate aggression and sexual libido...

i started taking Yasmin after i had my 5th child in July 2002. i was about 70 pounds over weight and my gyno said i would lose weight on this new wonder pill. i did, i lost 30 pounds and felt better than i ever had.
My skin was clear, my period light and i just consistently lost weight. i did notice that i was urinating quite a bit but didn't think much about it. About 3 years into taking the pill, my pharmacist mentioned to me that i should be having potassium levels drawn with this pill. I was a bit confused because i had read the literature that came with Yasmin when i started taking it(im a nurse and i just always research new meds i take) and it never once mentioned blood work. i had to harass my gyno because he thought it was useless but to appease me and because i mentioned to him i take a lot of ibuprofen for back pain he humored me and did the test. It was a little high but nothing crazy so i let it go even tho i mentioned that i was getting horrible muscle spasms all the time. he said my calcium was probably low. i accepted that because i had had 5 kids and figured i had depleted my supply. he mentioned that i could take Yasmin continuously without taking a sugar pill to keep me from having a period, said it was completely safe. so for the next 3 years i only had periods about 4 times a year. i raved to everyone how wonderful this pill was. i was still having muscle cramps but it was a small price to pay for no zits, no periods, no water weight, and i could eat whatever i wanted and had lost 30 pounds after one year of being on it though i never lost any after that.i didn't notice my hair was greasier than normal but i never connected it to the pill. i wanted to take the pill forever! that didn't work out thought when i lost my insurance and was forced to go off it because i just couldn't afford 70 a month. within the first couple of weeks i noticed acne appearing all over my face especially my nose and chin. i was 36 years old! far past the acne stage! i also noticed i felt bloated and my first period that came was like someone had released a flood gate. i went through 2 boxes of super tampons and a bag of pads in 3 days. thats about the time i noticed the weight gain. slowly over a period of 3 months i put on 3 or 4 pounds a week to now a whopping total of 30 pounds in 3 months. i was devastated. i knew that there were side effects of any medication and you assume those risks while taking it but not from not being on it anymore! the only good thing to come from getting off of it was those annoying muscle spasms completely stopped. i had been to the point that i couldn't even flex my toes or they would charley horse i had even gotten them in my jaw from yawning! now they were gone and replaced by fatigue, extreme weight gain and horrible acne and periods. i started blowing up and it didn't seem to be mainly weight, it seemed like fluid. i didn't urinate half as much as i used to it was like my body forgot how to make its own diuretic hormone. i could take a water pill and lose 10 pounds in 4 hours of fluid i knew that was not a good thing. i was scared as well as baffled. i went to my internist and he was shocked when he saw me my lungs were full of fluid, i had put on 30 pounds and was short of breath he ordered thyroid function tests and guess what? out of the blue my perfectly functioning thyroid (i had levels drawn the year before in routine tests) had stopped working when i got off Yasmin! so now i have to take diuretics because i don't seem to make enough of my own which i believe is thanks to Yasmin and i also feel it damaged my thyroid since its mechanism of action is inhibiting your adrenal system and thats what controls your thyroid. i am seriously considering filing a class action law suit based on the fact that for 3 years i never had my potassium levels checked because it wasn't advised by the manufacturer and i have experienced damage from this pill that i was not warned about in the package insert or by my doctor. i had the right to be informed and if they didn't know then the fda should have never approved it. i feel like ive been a guinea pig, and if anyone feels the same my number is ****** if we stand together maybe we can make them take this off the market and find out what has happened to those of us hurt already

After about 8 weeks of taking the 500mg dose, I have experienced some skin crawling, maybe a little itch on occasion.

Tonight I took an aspirin at 8:30, and niaspon at 9:00. Went to bed at 10:00. At 1:30 am I woke up and I was on fire! Head to Toe, itching all over..Pure misery and hell, it was intolerable. I immediately an another aspirin, took a shower, scratched myself with a towel, rubbed myself with cortisone, and took another aspirin.. After about an hour the itching has subsided with an occasional skin crawl.

I wanted to see if anyone else has had these symptoms so I googled 'niaspin extreme itch' and it brought me here.

I am supposed to up my dose to 1000mg a day, but now I am really worried about this itch. I see that I am not alone.

I started taking Yasmin on Monday April 21st, and by Wednesday morning I wanted off of it. I started getting really bad leg cramps all the time, I feel dizzy all the time, I have trouble concentrating, and I have trouble breathing. The worst part is that I have heart palpitations now. My heart feels all butterfly-like or it feels like it's beating really slowly really hard. I just spoke with my doctor, and she says to stop taking it immediately.

After reading this website I see I'm not the only one affected by horrible side-effects from Yasmin.

After I had a heart attack 3 years ago I had stents inserted I was put on Atenol, butemide, lisinopril, amoplodine, spirolactate and metroformin for my diabetes. Since taking these tablets I have suffered from some horrible side effects my weight has increased I cannot stand for long I get so out of breath I can only walk about 8 steps before I feel like I am going to colapse and my breathing gets really bad. I also suffer now from Lymphodema which is caused by excess water being made by the tablets lisinopril and the amoplodine my legs from the knees down to my toes are so swollen even though I take water tablets my legs feel like leads weights I have now become virtually house bound because I can hardly walk to get out of my house II get so out of breath now. I also cough up a lot of mucus all night which is clear and frofey my GP asked if I had ever suffered from asthma I said I have never had asthma in my life before, christmas I felt so bad my husband called a local GP in and he said that I had fluid on my lungs and an Xray revealed that I had fluid around my heart also I am convinced that these tablets were the cause of this I have to sleep sitting up I can't lay down now. I saw my GP and told her that I had read about the side effects of these drugs on the internet and I was sure these were causing my condition I asked if I could come off lisinopril, amoplodine and spirolactate and since I have come off these tablets although all my symptons have not completely disappeared yet I do feel a lot better this was five weeks ago that I stopped taking them. I asked my GP if there were any other tablets that I could take that were more suitable. I have suffered pain in my back in the kidney area as well and my potassium levels were very high. I have had diabetes for 52 years and my old GP told me that I would not live to see 40 years, the way that I was feeling I thought my god my times up.

HEART PALPITATIONS
After a year on Yasmin, I developed heart palpitations. They first began occurring at night, while lying in bed, then progressed to the point that my heart no longer had normal beats. My heart was fluttering constantly. My OBGYN said that arrhythmia due to Yasmin is "impossible", and a $1,200 work-up by a noted cardiologist ruled that my problem was due to "emotions". Just 10 days after quitting Yasmin, my heart beat returned to normal, and I have not had one heart palpitation since.

my symptoms were with Prevacid, I believe that these drugs all have the same dangerous side effect. It started with extreme weakness, numbness and pins and needles in my legs and arm. Now after 9 weeks of stopping the Prevacid I feel shaky and tremors. I take b-12 injections because it seemed to have depleted me of my normal b-12 levels. I am hoping this is the problem and will improve . until than my doctor has me going to a neurologist to assure it is nothing else . mri of brain is normal and thyroid is normal. HOW LONG UNTIL THESE SYMPTOMS SUBSIDE , PLEASE TELL ME THEY WILL GO AWAY.

I am 49 and my bad acne started to return and I started getting a receeding hairline. My OB put me on Yaz. The hair has continued to reced at an alarming rate - so it did not help with that. I still am breaking out alot, but I have since discovered a device called the ZitZapper which works really well (I wish it had been invented 30 years ago when I was at my worst). My skin has dried out alot which I really like. It's still oily in comparison to other peoples, but at least my eyeliner is not melting in 4 hours like it used to. I have no experienced any of the moodiness others complain of.

But I have gotten a yeast infection every other month and I am very dry. And my sex drive has never been lower. In fact, I have no sensation in the exterior tissues; I cannot acheive an orgasm, which I have never had problems with at all. The drospirenone in Yaz is derived from a "water pill" that gives men erectile disfunction, so the lowered libido is not a surprise.

I have lost weight (about 5 lbs); the pill makes your appetite diminish, especially if you drink alot of water. My breasts seem fuller but are not sore. In general I like the effect it has has on my body.

The first week of every month, I feel very tired but this only lasts the first week.

The package insert fot YAZ is clear that you should get tested for Potassium levels your first month. Your kidneys cannot process the minerals and be trying to clear other substances. The itching all over that I was feeling and others complain of - this is limited kidney function. A blood test will confirm this.The first month I was on Yaz I could not eat any high potassium foods without feeling sick. I ate a can of tuna and was sick for 2 days. I had a weird metallic taste in my mouth for the first 6 weeks. I can pretty much eat anything now without feeling sick.

I take fish oil daily to thin the blood to try to stave off clots.

I am going to try something else though to try to stop the hair loss.

I have just come across this site, while looking to find out why I have been experiencing heart palpitations for the past two months - out of the blue!!! and usually "exercise" induced. I had some tests and have been told they are Premature Atrial Contractions "PACs". I started taking Yasmin in April, after having tried others over the past year (tri-cyclen lo and alesse) which did not work for me as the progestin was not strong enough. I am in my 40s and never took the pill before. Yasmin was great, it significantly reduced my "physical" pms (severe inflamation, severe bloating, severe sore breasts) which I experience for 2-3 weeks a month. However, sometime in mid to late June, I started getting palpitations/tremors out of the blue. The first episode freaked me out and lasted for about two weeks. At first I thought it was allergy medication mixed with my thyroid med, which can happen - but I cut out the allergy meds and still got them. They seem to come about 6hrs to a day after I fexercise/figure skate and they last from 2 to 5 five days. It's very irritating and nerve wracking, and I feel very agitated. I am also out of breath more than usual when walking up stairs, a little light headed and have some tightness in the chest. My legs also are weak, which makes no sense given my exercise regimen. I then lowered my thyroid replacement from .125 synthroid to .100 - too much thyroid med can cause some palpitations. Anyone who has mistakenly taken a second thyroid pill having forgotten that they already took one will understand. Even with the lower dose I am still getting the palpilations. I am totally at a loss as to why all of a sudden this is happening to me (perhaps perimenopause??). I have had the odd flutter here and there in my live, but nothing like this. It just doesn't make any sense ag ll. Can one's health just change like this overnight?. I am otherwise healthy, slim, have "lower" blood pressure (apprx 100-90/70-60)I skate 3 to 5 times a week, I have a full time job and yes I do push myself, but this is getting ridiculous. The only thing I can attribute it to is the Yasmin, ... but my symptoms only started after a few months not instantly, whereas it would seem that most of the the women here noticed the side effects faster. I hate to stop the Yasmin because I will have to return to pms "hell", but I suppose I will give it a try to see if the palpitations subside. At this point, I have been offered a low dose "beta blocker" and have refused. I am stunned to think that all of a sudden I have heart issues, especially since my Dr has always kidded me my that I will never have heart problems with my blood pressure. I will stop the Yasmin tonight and post another message in a few weeks one it is out my system. Here's hoping it is the Yasmin.
KarenSkaterGirl

I have only been on Toporal for about a month, 50mg/day. My B/P is now stable, but I am having intermittant chest pain that travels down my arm and into my jaw. I am a 50 yr old female in good shape. I can say that I feel some anxiety daily and that is not normal for me. I have not noticed a weight gain, yet my doctor called today to tell me my potassium levels are too high. Has anyone else experienced this from this drug?

My doctor has taken me off Lisinipril because of elevated calcium and potassium levels, not to mention the terrible side effects of this drug, like fatigue, weakness, anxiety, etc. The doctor is hoping to wean me off high blood pressure drugs and trying to achieve a normal pressure by diet and exercise. I have been off the Lisinipril for two weeks. I am still feeling some of the side effects, however, I am wondering if anyone out there has been taken off Lisinipril and been able to bring down their blood pressure without drugs....anyone out there?

I never saw much effect of taking the generic version of Maxide. Perhaps less blurred vision while taking it. This last year I gained weight and my heartbeats have gotten worse in regularity. So I stopped it currently to see what happens, and am monitoring blood pressure, as well as dieting and excercise. just tring to see if calcium and potassium levels are out of balance.

Anti Androgen and Anti-Mineralocortoid Properties of Yasmin's Ingredients:

While I continue learning about Yasmin and its "unique" properties and ingredients, wanted to share some other information that I thought could be helpful for other women here. It really is a bit of a puzzle learning about all these things, what they mean to our bodies and why we experienced some of the many side effects that we did while taking it or in the healing coming off of it.

Two acting effects in Yasmin are anti-mineralocortoid (diasperonone) and anti-androgenic effects (Spironolactone). While this is something most of us don't read about or understand about one of the many ways Yasmin works, I think it is really important in the larger picture-putting together the many ways in which the ingredients may act upon our bodies:

MINERALOCORTOID
(Yasmin has ANTI-mineralocortoid function/effects):

Mineralocorticoids are a class of steroid hormones characterised by their similarity to aldosterone and their influence on salt and water balance. (note Yasmin has diasperonone as an acting ingredient which acts as a potassium sparing diuretic.)

The primary endogenous mineralocorticoid is aldosterone. Yasmin has anti-aldosterone properties. Aldosterone acts on the kidneys to provide active reabsorption of sodium and an an associated passive reabsorption of water, as well as the active secretion of potassium. Note: Yasmin has diasperonone that is a potassium sparing diuretic. This in turn results in an increase of BLOOD PRESSURE and BLOOD VOLUME.

Aldosterone is produced in the cortex of the adrenal gland its secretion is mediated principally by angiotensin II, but also by ACTH (adrenocoritotrophic hormone) and local potassium levels.

Hyperaldosteronism (the symtpom caused by elevated aldosterone) often shows up as:

1. Hypertension-high blood pressure. High blood pressure that is arterial in nature gives a higher risk of heart attack or stroke than any other disease. Persistent hypertension/high blood pressure is one of the risk factors for strokes, heart attacks, heart failure and arterial aneurysm, and is a leading cause of chronic renal failure (which means chronic kidney failure)

2. Accelerated excretion oif potassium ions. With extreme K+ loss (note Yasmin has potassium sparing diuretic), ther is muscle weakness and eventually paralysis

Underproduction, or hypoaldosteronism, leads to the salt wasting state associated with Addison's disease (also known as chronic adrenal insufficiency or hypocortisolism) is a rare endocrine disorder in the body produces insufficient amounts of adrenal steroid hormones (glucocorticoids and mineralocorticoids) (note Yasmin has anti-mineralocorticoid effect)-it is essentially the inability of the Adrenal Gland to produce adquate amounts of CORTISOL in response to stress. This is an Endocrine discorder caused by high levels of cortisol in the blood. Cortisol is released from the adrenal gland in response to ACTH being released from the pituitary gland in the brain. Or..

HYPOADRENIA/ADRENAL FATIGUE:
The adrenal glands are part of the body's mechanism for short term stress response and management. (Note Yasmin's effect on adrenal glands). They are involved in the production of the hormone adrenaline (also known as EPINEPHRINE **-the famous fight or flight chemical released in stressful situations which increases the body's metabolic energy regulation and control system-and thus control to an extent the energy available to body systems.

Theorized by alternative medical practictionerS that under conditions of long term stress, the adrenal glands can become less responsive to circumstance and cease to function optimally leading to a wide* but slightly vauge range of FATIGUE AND STRESS RELATED CONDITIONS including a greater likelihood of psychological conditions such as depression and possibly certain other mood disorders.

SYMPTOMS OF ADRENAL FATIGUE:
1) DEPLETION OF ENERGY
2) LOSS OF RESILIENCE
3) FATIGUE
4) NERVOUSNESS
5) ANXIETY
6) EXACERBATED PMS
7) DEPRESSION
BRAIN FOG
9) CARBOHYDRATE CRAVINGS
10) ALLERGIES
11) MUSCULAR PAIN
12) JOINT PAIN
13) IRRITABLE BOWEL SYNDROME

Does this set off any bells or what ladies ? Very likely makes taking an Adrenal Function test as well as seeing an Endocrinologist.

CORTICOSTEROIDS:
Additionally, the corticosteroids functions, prodcued in the adrenal cortex include that of stress response, immune response, regulation of inflammation*, carbohydrate metabolism, protein catabolism, blood electrolyte levels and behavior. Interesting is the fact that Yasmin's side effects include trouble with colds and flu, "nervousness", insulin resistance (which is carbohydrate/sugar intolerance), -good likelihood for creating an imbalance in our electrolytes-which are minerals due to the potassium sparing diuretic. If you were like me, reading through this was unbelievable to me.

Yasmin's ANTI-ANDROGEN is Spironolactone
Synthetic steroid which is commonly used as a diuretic or as an Anti-androgen. -Potassium sparing diuretic. This on its own is a weak diuretic. Due to its anti-androgenic effect, it is common component in hormone therapy for male-to-female Transsexual and transgendered people and is also used for treating hair loss and acne in women....hmmm. Why then I wonder some women report the hair loss. It is marketed as a drug to treat acne.

Spironolactone inhibits the effects of aldosterone by competing for intracelluar aldosterone receptor. This increases the secretion of water and sodium, while decreasing the excretion of potassium. Spironolactone has a fairly slow onset of action, taking several days to develop and similarly the effect diminishes slowly.

ADVERSE REACTIONS TO SPIRONOLACTONE:
include menstrual irregularities and testicular atrophy, ataxia, erectile dysfunction , drowsiness and rashes*. A carcinogenic effect has been demonstrated in rats. Carcinogen is a term that refers to any substance or radiation which is an agent directly involved in the promotion of cancer or in faciliation of its propagation.

ATAXIA:
Steady and clumsy motion of the limbs or torso due to failure of the gross coordination of muscle movements. This often occurs when parts of the nervous system that control movement are damaged. People with ataxia experience a failure of muscle control in their arms and legs.

There is loads to consider on this front and lots of information available. I hope that this is helpful as you make your way through both understanding what some of your symptoms may be as well as informing/sharing your knowledge with a chosen medical practictioner.

Recommended for Adrenal Support:
Panthonene, B6, Zinc, magnesium and Vitamin C as they play a critical role in the optimal functioning of the adrenal gland and in the manufacture of adrenal hormones (which are suppressed taking Yasmin).

Take a look at:
Siberian and Panax Ginsengs

panthothenic acid

Ashwagandha
provides adrenal and immune support

Astralagus
in New Chapter Organic's multi and many other vitamins-used historically for strenghtening and regulating the immune system-as a tonic

Shisandra
improves immune function, increasing physical performance and endurance and for increasing resistance to disease and distress. Also possibly effective for increasing concentration due to the variety of lignans found in the fruit.

Maca-Peruvian Ginseng-
used for chronic fatigue syndrome, enhancing energy and stamina. In the female reproductive system, its use for enhancing fertility, regulating the menstrual cycle, treating common menopause symptoms and to increase libido. Its benefits have been known to the people of Peru for many generations.

Androgens are the precursor of all estrogens (the female sex hormones). the primary and most well known androgen is testosterone.

A subset of androgens, called adrenal androgens, includes any of 19-carbon steroids synthesized by the adrenal cortex, the outer portion of the adrenal gland that function as weak steroids or steroid precursors, including DHEA (dehydroepiandrosterone), DHEA-S (dehydroepiandrosterone), and androstenedione. Because Yasmin's ingredients have an anti-androgen effect that effect our adrenal glands-women with adrenal problems are advised not to take it.

Besides testesterone (which is responsible for sexual libido/function), other androgens include:

1) DHEA
(dehydroepiandrosterone: -a steroid hormone produced from cholesterol in the adrenal cortex which is the primary precursor of natural estrogens.

2) Androstenedione (Andro)-
an androgenic steroid, which is produced in the testes, adrenal cortex and ovaries*. While androstenediones are converted metabolically to testosterone and other androgens, they are also the parent structure of estrone. Estrone is an estrogenic hormone secreted by our ovaries. It is one of three estrogens which also include estriol and estradiol. Estrone is the least prevalent of the three hormones, estradiol being prevalent almost always in the female body, estriol being prevalent primarily during pregnancy.

3) Androstenediol:
the steroid metabolite that is thought to act as the main regulator of gonadotropin secretion-protein hormones secreted by gonadotrope cells of the pituitary gland. The two principle gonadotropins are LUTENIZING HORMONE (LH) and FOLLICLE STIMULATING HORMONE (FSH)-both of these are what are naturally release by our bodies on a monthly cycle are part of natural menstruation. The third human gonadotropin is human chorionic gonadotropin (hCG) produced by our placentas during pregnancy.

4) Androsterone:
a chemical by-product created during the breakdown of of androgens-or derived from progesterone -that also exerts minor masculnizsing effects, but with one seventh the intensity of testesterone.

5) DHT Dihydrotestosterone-
a metabolite of testosterone that is actually a more potent androgen in that it binds more strongly to androgen receptors.

FUNCTIONS OF ANDROGENS:
(keep in mind Yasmin has anti-androgenic properties):

Muscle mass:
Androgens promote the enlargement of skeletal muscle cells and probably act in a coordinated manner to enhance muscle function. (note: how many of us have experienced muscle fatigue and that Asthenia-was experienced by women in the Clinical Trials.

BRAIN:
Circulating levels of androgens can influence human behavior because some neurons are sensitive to steroid hormones. Androgen levels have been implicated in the regulation of human AGGRESSION and LIBIDO. Note, Yasmin's ingredients have anti-androgenic effects. That means essentially translates as suppressing the effects that androgen has in our bodies to regulate aggression and sexual libido...

the mood swing side effect is very real. I'm currently taking a very small dose of prozac to counteract it. it doesn't effect everyone that way, and from what I understand, it can be just a temporary side effect due to the titration. once you stablize on a dose, it should lessen I'm told. after I nearly bit the head off a produce guy at nearby market for no reason at all, I knew I didn't want to wait and see, lol.

i've been on it for about 10 months now and i've had plummeting potassium levels, so much so the doc prescribed prescription potassium supplements and a excellent quality multivitamin plus minerals. that seems to be doing the trick.

I am showing hair loss and extreme weight loss too (so far over 30lbs), problems with gums. I can treat the gum problem with biotene, but the hair loss is a problem and the weight loss, well, i can stand to lose a few lbs.

I also have night sweats which are just weird and have problems with body temperature regulation.

all this on a whopping 45 mg a day!

still, I love my topamax. it's the only thing that's eliminated most of my every other day migraines.

Guest 38149-

good for you! We are delighted needless to say. If you haven't checked out the UK forum-see the link in emails below-highly recommend you do so. Sarah/flowerbabies set this up and its grown alot.

Yes-I did experience trouble sleeping and suspect it was from low magnesium levels/elevated potassium levels-now after 2 months on a 1200/1200 calcium/magnesium supplement by Rainbow Light-with enzymes that aid digestion-has mostly subsided.

J

If you are experiencing palpitations, chest pain, see your Doctor or go to ER immediately. Have your potassium levels checked promptly to ensure that you have not developed Hyperkalemia (excess potassium) in your blood which is likely and happened to me becuase of the potassium sparing diuretic in Yasmin*. Hyperkalemia can be lethal and is extremely dangerous and a risk taking Yasmin.

Erykah-I haven't seen anyone whose tried/used St. john's Wort but would recommend instead having your hormone levels and your adrenal function tested? Oftentimes, after Yasmin, becuase of the diuretic flushing that occurs (constant peeing/urinating) it throws off our electrolyte and mineral balances in addition to that it suppresses our adrenal glands. I have found success with B vitamins (A B stress tab) or a whole food/bio-available Vitamin*. The whole food and bioavailability part is really important-because it is what makes it more accessible/useable by your body. Also-take a calcium and magnesium supplement if you find you are low on magnesium which is one of the minerals Yasmin's diuretic depletes*. I'm taking one that is equivalent ratios: 1:1-1000 of each because minerals compete with one another so taking a calcium that is higher will not give you the benefit of the magnesium. Low magnesium levels effects the health of all the muscles in our bodies-including the heat and if oftentimes what causes the murmurs/palps.

Okay, so I think I may have stumbled on something more.....for all of you out there who have expeirenced the irregular heart rhythms....here's more on what I found in research about potassium. I learned that this was one of the greatest risks of Yasmin...but had no idea I was at 5.7 in blood tests just confirmed this morning after 3 months of being off of Yasmin and just last Dec. 2005-it was 4.7? So now, I am starting to wonder if my Adrenal Glands may not be doing their job as noted below to the release of adolsterone?

Why is the Test Performed?

Potassium (K+) is the major positive ion within cells and is particularly important for maintaining the electric charge on the cell membrane. This charge allows nerves and muscles to communicate and is necessary for transporting nutrients into cells and waste products out of the cell. The concentration of potassium inside cells is about 30 times that in the blood and other fluids outside of cells.

Potassium levels are mainly controlled by the steroid hormone aldosterone. (For more information see the aldosterone test.) Aldosterone is secreted from the adrenal gland when levels of potassium increase. Aldosterone, in turn, causes the body to rid itself of the excess potassium.

Metabolic acidosis (for example, caused by uncontrolled diabetes) or alkalosis (for example, caused by excess vomiting) can affect blood potassium.

Small changes in the potassium concentration outside cells can have substantial effects on the activity of nerves and muscles. This is particularly true of heart muscle. Low levels of potassium cause increased activity (which can lead to an irregular heartbeat), whereas high levels cause decreased activity. Either situation can lead to cardiac arrest in some circumstances.

In normal people, taking potassium supplements or potassium-containing drugs is of no consequences, because the kidneys efficiently dispose of excess potassium.

SARAH: syberlib, #35391

HOW DID YOU KNOW YOU HAD A MINI-STROKE? WHAT WERE YOUR SYMPTOMS PRIOR, DURING AND FOLLOWING? Were you diagnosed and if so what were the tests they conducted?

I feel so sorry that you were on this pill since it came out. 2001 is when it was approved in the U.S. and now it is being sold like crazy-heavily advertised.

I started Yasmin in January 2004. I went off in September 2006 so I was on it for 2.5 years. It was originally prescribed for me for anxiety interestingly enough because so many women here reported problems with anxiety while on it and then getting off of it.

I got off following 4 months of increasing chest pain. Started on the left side and then a month later, traveled across my chest and another month later primarily on my left side. This occurred usually the week just prior to my menstrual cycle so I expect that it has something to do with the hormone level changes just prior to the menses.

While on Yasmin, it made me so exhausted, I would shower and feel ready to go right back to bed. The Doctor recommended I take it at night so I did and it made getting up in the morning that much more difficult.

I went to the bathroom excessively due to the diuretic in Yasmin. no matter how much water I consumed, I constantly felt de-hydrated.

I had incredible fatigue while on Yasmin. My ears stopped up to the point of being painful and noticed right after I would take it that my ears would "pop" like they do on an airplane. This would last for 1-2 hours following taking it. I saw a hearing doc who told me that they've known for years that Ortho-contraceptives are odo-toxic meaning that they are toxic to the fluid levels of the inner ear. The inner ear consists of potassium and sodium fluid, so due to this pill's naturally increasing potassium levels, it made sense although a pharmacist, the prescribing Doctor and RN I saw to have an EKG done did not know this.

I've been off now for 3 plus months. However, to ease symptoms, I went onto Orthocept from September through December. Although some of the symptoms got better, the chest pains still continued to come the week before my period. What I want to know is how one knows if they are suceptible to a heart attack or stroke. The RN told me the EKG was normal but confirmed a returning heart murmur I had had years prior. When I was originally told I had this murmur back in 1999, a Naturopathic doctor said it was due to having low progesterone and said that it would likely go away on something like Orthocept. It did. However, after 2.5 years on Yasmin, it came back.

FOR EVERYONE WHO HAS POSTED OR IS NOT POSTING ON THIS SITE-I HIGHLY RECOMMEND KEVIN TRUDEAU'S BOOK ON NATURAL CURES. I'VE BEEN READING SECTIONS OF THIS FOR MONTHS UNTIL MY BROTHER GAVE IT TO ME FOR MY BIRTHDAY THIS MONTH. HE BASICALLY TAKES THE POSITION THAT ALL PRESCRIPTION DRUGS AS WELL AS NON-PRESCRIPTION CAUSE ILLNESS. DEPRESSION. ANXIETY. YEAST INFECTIONS. FATIGUE. MUSCLE SOARNESS. YOU NAME IT. EVERYTHING I'VE READ TO DATE I'VE KNOWN AT AN INTUITIVE LEVEL. THAT BASICALLY, MUCH TO ALL OF SCIENTIFIC MEDICINE-THAT IS PRESCRIPTION AND NON-PRESCRIPTION TREATS SYMPTOMS AND NOT NOT CAUSE AND CREATES AN IMBALANCE IN HEALTH THAT LEADS TO OTHER HEALTH PROBLEMS. I THINK THAT THIS IS BASICALLY TRUE AND I WOULD HEED WARNING TO ALL WOMEN SEEKING RELIEF FROM ANTI-DEPRESSANTS OR ANTI-ANXIETY MEDS. THEY ARE DEADLY.

IN ADDITION-EVERY WOMAN I KNOW HAS INCREASED ENERGY AND IRRITABILITY JUST PRIOR TO HER PERIOD. IT IS A NORMAL RESPONSE TO THE CHANGE IN HORMONE LEVELS IN YOUR BODY DURING THIS TIME. I USUALLY FIND THAT INCREASING ACTIVITY LEVEL, LOTS OF EXERCISE, AVOIDING CAFFEINE AND SUGAR ARE CRITICAL AND RELIEVE MOST TO ALL OF THESE SYMPTOMS.

The other thing I would like to mention is that sensations of feeling "blue" or "sad" are just as normal as feelings of bliss and happiness. We're raised to think that we are supposed to be these jolly all smile faces and if you aren't' "happy", that something is wrong. So, I'd just say, that while some diagnosis about imbalances may be very real, I'd recommend doing alot of reading and research prior to putting anything else into your body or taking any other medications. They all likely cause other problems.

I am, after all this time, quite disturbed by this and what I expect are millions of other responses by people taking an array of medications that cause such severe symptoms and sometimes death. After 6 years on the market, how its still being pushed so heavily. If you read Kevin Trudeau's book, you'll see that much of the pharmaceutical and medical industry isn't concerned with treating the cause of your symptoms, but instead recommending medication after medication to treat the symptom.

Exercise and stress relief as critical as a healthy diet which today has become more and more difficult to create and make a discipline with lifestyle but it is absolutely critical. All these pills, I believe are wreaking havoc and hell on people all over the world.

I tried Yaz (lower dose form of Yasmin) for two months and it made me give up on birth conrol completely. I had many ear aches/problems but no infection.I also had some un explained chest pains. My main complaint though is when I was on the reminder pills and when I stopped the pill I got severe dry skin. I have been very oily all my life. I am also having nervousness and problems sleeping. I think it has affected my potassium levels or adrenal glands (as another member posted) because I feel like I did when I was ill before I had my gall bladder out a few years ago. I have not taken any mediceines or changed any routines during this time. I have been on 4 different birth controls for the last 8 years and this was the worst. I hope I will feel normal again.

to Murph70,

Are you serious that you were almost blind? Strange how the more I think about all of this and the things that occurred during those 2.5 years, the more realize how much was linked to taking Yasmin. This is crazy. I read through so many of these emails and I too was advised by both the prescribing doctor as well as an RN that Yasmin could not be responsible for the symptoms I was experiencing. Makes me absolutely nuts that this is happening to so many women, being advertised so heavily and that people in the medical field prescribing it are unaware and discounting.

Can anyone advise what treatment has been the most effective for coming off of Yasmin? Ive been off now for two month. I still have alot of pressure in both ears and interestingly noticed several people who advised they had colds coming off of it. I got really sick immediately following coming off it with someone that took me two months to get rid of. Then, after two weeks, I just got another cold. I've never been sick like this!

It occurred to me that it could well likely be due to how the increased potassium levels or changes to the electrolytes have effected the immune system? Anyone else had this experience?

While I can't say I noticed a change in sexual drive (except I will likely notice that more as I am off of it for longer), did notice I was exhausted all the time. ALL THE TIME. I would shower in the morning and then want to go right to bed. It depleted me and all my energy. And like some other people, lost interest in everything I enjoyed.

I've never been able to find vitamins that I could take that didn't make me feel kinda sick. How much magnesium is recommended? Any particular type of vitamin recommended?