Potassium sparing diuretic symptoms and conditions

Two acting effects in Yasmin are:
ANTI-MINERALOCORTOID (Diasperonone)
and
ANTI-ANDROGENS (Spironolactone)

MINERALOCORTOID
(Yasmin has ANTI-mineralocortoid function/effects):
-----------
Mineralocorticoids are a class of steroid hormones characterised by their similarity to aldosterone and their influence on salt and water balance. (note Yasmin has diasperonone as an acting ingredient which acts as a potassium sparing diuretic.)

The primary endogenous mineralocorticoid is aldosterone. Yasmin has anti-aldosterone properties.

Aldosterone acts on the kidneys to provide active reabsorption of sodium and an an associated passive reabsorption of water, as well as the active secretion of potassium.
Note: Yasmin has diasperonone that is a potassium sparing diuretic. This in turn results in an increase of BLOOD PRESSURE and BLOOD VOLUME.

Aldosterone is produced in the cortex of the adrenal gland its secretion is mediated principally by angiotensin II, but also by ACTH (adrenocoritotrophic hormone) and local potassium levels.

Hyperaldosteronism (the symtpom caused by elevated aldosterone) often shows up as:
-------------------
1. Hypertension-high blood pressure. High blood pressure that is arterial in nature gives a higher risk of heart attack or stroke than any other disease. Persistent hypertension/high blood pressure is one of the risk factors for strokes, heart attacks, heart failure and arterial aneurysm, and is a leading cause of chronic renal failure (which means chronic kidney failure)

2. Accelerated excretion of potassium ions. With extreme K+ loss (note Yasmin has potassium sparing diuretic), there is muscle weakness and eventually paralysis

Underproduction, or Hypoaldosteronism:
-----------------------------
leads to the salt wasting state associated with ADDISON'S DISEASE (also known as chronic adrenal insufficiency or hypocortisolism):
is a rare endocrine disorder in the body produces insufficient amounts of adrenal steroid hormones (glucocorticoids and mineralocorticoids) (note Yasmin has anti-mineralocorticoid effect)-it is essentially the inability of the Adrenal Gland to produce adquate amounts of CORTISOL in response to stress. This is an Endocrine discorder caused by high levels of cortisol in the blood. Cortisol is released from the adrenal gland in response to ACTH being released from the pituitary gland in the brain. Or..

HYPOADRENIA/ADRENAL FATIGUE:
-----------------------------------
The adrenal glands are part of the body's mechanism for short term stress response and management. (Note Yasmin's effect on adrenal glands). They are involved in the production of the hormone adrenaline (also known as EPINEPHRINE **-the famous fight or flight chemical released in stressful situations which increases the body's metabolic energy regulation and control system-and thus control to an extent the energy available to body systems.

Theorized by alternative medical practictionerS that under conditions of long term stress, the adrenal glands can become less responsive to circumstance and cease to function optimally leading to a wide* but slightly vauge range of FATIGUE AND STRESS RELATED CONDITIONS including a greater likelihood of psychological conditions such as depression and possibly certain other mood disorders.

SYMPTOMS OF ADRENAL FATIGUE:
------------------------------------------------------
1) DEPLETION OF ENERGY
2) LOSS OF RESILIENCE
3) FATIGUE
4) NERVOUSNESS
5) ANXIETY
6) EXACERBATED PMS
7) DEPRESSION
8) BRAIN FOG
9) CARBOHYDRATE CRAVINGS
10) ALLERGIES
11) MUSCULAR PAIN
12) JOINT PAIN
13) IRRITABLE BOWEL SYNDROME

CORTICOSTEROIDS:
(Yasmin's ingredients contain anti-mineralocortoid)
----------------------------------------------
Additionally, the corticosteroids functions, produced in the adrenal cortex include that of stress response, immune response, regulation of inflammation*, carbohydrate metabolism, protein catabolism, blood electrolyte levels and behavior.

Yasmin's listing of possible side effects include trouble with:
-colds and flu
-"nervousness"-not "anxiety" but "nervousness" -insulin resistance (which is carbohydrate/sugar intolerance),

Yasmin's ANTI-ANDROGEN is Spironolactone:
Synthetic steroid which is commonly used as a diuretic or as an Anti-androgen. Potassium sparing diuretic.
-------------------
This on its own is a weak diuretic. Due to its anti-androgenic effect, it is common component in hormone therapy for male-to-female Transsexual and transgendered people and is also used for treating hair loss and acne in women.

Spironolactone inhibits the effects of aldosterone by competing for intracelluar aldosterone receptor. This increases the secretion of water and sodium, while decreasing the excretion of potassium. Spironolactone has a fairly slow onset of action, taking several days to develop and similarly the effect diminishes slowly.

ADVERSE REACTIONS TO SPIRONOLACTONE:
---------------------------------------
-menstrual irregularities and testicular atrophy
-ataxia-muscle weakness/atrophy
-erectile dysfunction
-drowsiness
and rashes*.
A carcinogenic effect has been demonstrated in rats. Carcinogen is a term that refers to any substance or radiation which is an agent directly involved in the promotion of cancer or in faciliation of its propagation.

ATAXIA:
-------------
Steady and clumsy motion of the limbs or torso due to failure of the gross coordination of muscle movements. This often occurs when parts of the nervous system that control movement are damaged. People with ataxia experience a failure of muscle control in their arms and legs.

Androgens are the precursor of all estrogens (the female sex hormones). the primary and most well known androgen is testosterone.

A subset of androgens, called adrenal androgens, includes any of 19-carbon steroids synthesized by the adrenal cortex, the outer portion of the adrenal gland that function as weak steroids or steroid precursors, including DHEA (dehydroepiandrosterone), DHEA-S (dehydroepiandrosterone), and androstenedione. Because Yasmin's ingredients have an anti-androgen effect that effect our adrenal glands-women with adrenal problems are advised not to take it.

Besides testesterone (which is responsible for sexual libido/function), other androgens include:

1) DHEA
(dehydroepiandrosterone: -a steroid hormone produced from cholesterol in the adrenal cortex which is the primary precursor of natural estrogens.

2) Androstenedione (Andro)-
an androgenic steroid, which is produced in the testes, adrenal cortex and ovaries*. While androstenediones are converted metabolically to testosterone and other androgens, they are also the parent structure of estrone. Estrone is an estrogenic hormone secreted by our ovaries. It is one of three estrogens which also include estriol and estradiol. Estrone is the least prevalent of the three hormones, estradiol being prevalent almost always in the female body, estriol being prevalent primarily during pregnancy.

3) Androstenediol:
the steroid metabolite that is thought to act as the main regulator of gonadotropin secretion-protein hormones secreted by gonadotrope cells of the pituitary gland. The two principle gonadotropins are LUTENIZING HORMONE (LH) and FOLLICLE STIMULATING HORMONE (FSH)-both of these are what are naturally release by our bodies on a monthly cycle are part of natural menstruation. The third human gonadotropin is human chorionic gonadotropin (hCG) produced by our placentas during pregnancy.

4) Androsterone:
a chemical by-product created during the breakdown of of androgens-or derived from progesterone -that also exerts minor masculnizsing effects, but with one seventh the intensity of testesterone.

5) DHT Dihydrotestosterone-
a metabolite of testosterone that is actually a more potent androgen in that it binds more strongly to androgen receptors.

FUNCTIONS OF ANDROGENS:
(keep in mind Yasmin has anti-androgenic properties):

Muscle mass:
Androgens promote the enlargement of skeletal muscle cells and probably act in a coordinated manner to enhance muscle function.

BRAIN:
Circulating levels of androgens can influence human behavior because some neurons are sensitive to steroid hormones. Androgen levels have been implicated in the regulation of human AGGRESSION and LIBIDO.
Note, Yasmin's ingredients have anti-androgenic effects. That means essentially translates as suppressing the effects that androgen has in our bodies to regulate aggression and sexual libido...

Hello-

I took Yasmin for a 1.5 years. I am now 2 years post Yasmin. In hind-sight, had I known what I would live through both while taking Yasmin as well as the 2 years following, I would never have taken it in the first place.

I am going to summarize some of those side effects below:

For the first 1.25 years, it seemed like I was living in an dream. I was that spaced out all the time. No affect, if you will. I felt like a zombie.

Exhaustion/Fatigue:
I became lethargic all the time. Previously, being very athletic, I had no energy at all. A walk made me yearn for a nap. 2 years post Yasmin, I am still trying to recover and bring back all the muscle tone I lost. Reading through alot of possible side effects, ataxia (muscle atrophy/loss) was one of them I suspect could be linked to becoming dehydrated.

Painful plugged eardrums:
Every morning after i would take Yasmin, my ears would have this "popping sensation" much like what it feels like when you are on an airplane and the pressure changes. Over time, my ears became quite painful like I had alot of pressure built up in them. I later learned from a Hearing Doctor that it could well have been the potassium sparing diuretic as the inner ears are composed of potassium/sodium and the diuretic could offset its balance. This doctor also told me that in their field they have known forever that artificial/synthetic hormones are toxic to the inner ears. No other doctor I saw coming off of Yasmin knew this...

Melasma:
I developed brown spots on my forehead, beneath my eyebrows and on both cheeks within starting Yasmin in the first month.

Constant Urination:
I urinated every 15 minutes for 1.5 years straight that I was on Yasmin. Learned later about the potassium sparing diuretic in it a little too late. My blood tests showed I was dehydrated and was deficient in Folic Acid and Vitamin B12. Both 2 common deficiencies seen with artificial/synthetic hormone use.

Chest Pain:
1.25 years into taking Yasmin, at the onset of menses, I developed this pressure in my chest and sharp stabbing pains. The next month, again at the onset of menses, the pressure occurred again, this time spreading across my chest. I went to see a Doctor at that point who discounted that Yasmin could be involved at all. (Not sure why a member of the medical community would say that given I have since read a number of articles that suggest that Yasmin and Yaz both run a higher risk for clots/pulmonary embolisms then other birth control pills). Regardless, I had a chest x-ray to ensure my heart was not enlarged and had an EKG which just showed an abnormally slow heartbeat-Sinus Bradycardia. It was recommended at that time that I have a ECG (echo-cardiogram). Tests start at $5000 each and I did not have coverage for this kind of test.

I went off of Yasmin now, almost 2 years ago. Going off I spent the last 2 years getting sick every month at the onset of menses with severe bronchitis, chest pain that still occurs at menses (I have since learned can also be brought on by low levels of oestrogen and progersterone at menses) and gained 30 lbs.

Blood tests showed I was depleted of Vitamin D, B and Folic Acid, dehydrated and also had elevated potassium (a possible risk with Yasmin's potassium sparing diuretic.

I would encourage everyone to google anti-mineralocortoid (diasperonone) and anti-androgenic effects (Spironolactone)

These are both acting ingredients in Yasmin.

This has been the toughest couple of years in my lifetime. Initially it seemed like a great pill. My skin cleared up, I lost weight and my periods were only 3 days long. On that note, it took a whole year and half for my periods to go back to 5 days from 3 days long so again, doctors telling me that Yasmin would not and could not be affecting my body after stopping, just went to show it took that long for my own body to start re-producing its own natural hormones.

Through all of this, I have met amazing women and other survivors who have offered enormous support. I would suggest to any of you that find your way here to trust yourself and your body first and foremost to what anyone else may discount or try and remedy with anti-anxiety and anti-depressant medications. There are a host of amazing authors out there as well who enlightened me enormously on the role of hormones in our bodies, and ultimately, their balance to our overall health and immune function:

Dr. Lee and Dr. Hotze. They both have websites and books which are wonderful. I would also suggest googling Yasmin Survivors online, which will take you to another resource/forum of women who are sharing side effects and healing and survival techniques coming off of Yasmin. The site is: ******

LOW POTASSIUM LEVELS,DIZZINESS,NAUSEA,VOMITING,FEELING FAINT/FAINTING,MUSCLE CRAMPS/SPASMS,FREQUENT URINATION,FLU-LIKE SYMPTOMS,TIREDNESS,WEAK,HEART PALPATATIONS; I AM ONLY 30 AND FEEL LIKE A 70 YEAR OLD WOMAN.I HAVE TO HAVE MY POTASSIUM LEVEL CHECKED ALL THE TIME BECAUSE IT KEEPS BOTTOMING OUT AND I WILL PASS OUT AND MY PRESSURE GETS TO LOW.BUT I NEED A BLOOD PRESSURE MEDICATION WITH A DIURETIC.WHAT ELSE CAN I USE I ASK YOU?

Anti Androgen and Anti-Mineralocortoid Properties of Yasmin's Ingredients:

While I continue learning about Yasmin and its "unique" properties and ingredients, wanted to share some other information that I thought could be helpful for other women here. It really is a bit of a puzzle learning about all these things, what they mean to our bodies and why we experienced some of the many side effects that we did while taking it or in the healing coming off of it.

Two acting effects in Yasmin are anti-mineralocortoid (diasperonone) and anti-androgenic effects (Spironolactone). While this is something most of us don't read about or understand about one of the many ways Yasmin works, I think it is really important in the larger picture-putting together the many ways in which the ingredients may act upon our bodies:

MINERALOCORTOID
(Yasmin has ANTI-mineralocortoid function/effects):

Mineralocorticoids are a class of steroid hormones characterised by their similarity to aldosterone and their influence on salt and water balance. (note Yasmin has diasperonone as an acting ingredient which acts as a potassium sparing diuretic.)

The primary endogenous mineralocorticoid is aldosterone. Yasmin has anti-aldosterone properties. Aldosterone acts on the kidneys to provide active reabsorption of sodium and an an associated passive reabsorption of water, as well as the active secretion of potassium. Note: Yasmin has diasperonone that is a potassium sparing diuretic. This in turn results in an increase of BLOOD PRESSURE and BLOOD VOLUME.

Aldosterone is produced in the cortex of the adrenal gland its secretion is mediated principally by angiotensin II, but also by ACTH (adrenocoritotrophic hormone) and local potassium levels.

Hyperaldosteronism (the symtpom caused by elevated aldosterone) often shows up as:

1. Hypertension-high blood pressure. High blood pressure that is arterial in nature gives a higher risk of heart attack or stroke than any other disease. Persistent hypertension/high blood pressure is one of the risk factors for strokes, heart attacks, heart failure and arterial aneurysm, and is a leading cause of chronic renal failure (which means chronic kidney failure)

2. Accelerated excretion oif potassium ions. With extreme K+ loss (note Yasmin has potassium sparing diuretic), ther is muscle weakness and eventually paralysis

Underproduction, or hypoaldosteronism, leads to the salt wasting state associated with Addison's disease (also known as chronic adrenal insufficiency or hypocortisolism) is a rare endocrine disorder in the body produces insufficient amounts of adrenal steroid hormones (glucocorticoids and mineralocorticoids) (note Yasmin has anti-mineralocorticoid effect)-it is essentially the inability of the Adrenal Gland to produce adquate amounts of CORTISOL in response to stress. This is an Endocrine discorder caused by high levels of cortisol in the blood. Cortisol is released from the adrenal gland in response to ACTH being released from the pituitary gland in the brain. Or..

HYPOADRENIA/ADRENAL FATIGUE:
The adrenal glands are part of the body's mechanism for short term stress response and management. (Note Yasmin's effect on adrenal glands). They are involved in the production of the hormone adrenaline (also known as EPINEPHRINE **-the famous fight or flight chemical released in stressful situations which increases the body's metabolic energy regulation and control system-and thus control to an extent the energy available to body systems.

Theorized by alternative medical practictionerS that under conditions of long term stress, the adrenal glands can become less responsive to circumstance and cease to function optimally leading to a wide* but slightly vauge range of FATIGUE AND STRESS RELATED CONDITIONS including a greater likelihood of psychological conditions such as depression and possibly certain other mood disorders.

SYMPTOMS OF ADRENAL FATIGUE:
1) DEPLETION OF ENERGY
2) LOSS OF RESILIENCE
3) FATIGUE
4) NERVOUSNESS
5) ANXIETY
6) EXACERBATED PMS
7) DEPRESSION
BRAIN FOG
9) CARBOHYDRATE CRAVINGS
10) ALLERGIES
11) MUSCULAR PAIN
12) JOINT PAIN
13) IRRITABLE BOWEL SYNDROME

Does this set off any bells or what ladies ? Very likely makes taking an Adrenal Function test as well as seeing an Endocrinologist.

CORTICOSTEROIDS:
Additionally, the corticosteroids functions, prodcued in the adrenal cortex include that of stress response, immune response, regulation of inflammation*, carbohydrate metabolism, protein catabolism, blood electrolyte levels and behavior. Interesting is the fact that Yasmin's side effects include trouble with colds and flu, "nervousness", insulin resistance (which is carbohydrate/sugar intolerance), -good likelihood for creating an imbalance in our electrolytes-which are minerals due to the potassium sparing diuretic. If you were like me, reading through this was unbelievable to me.

Yasmin's ANTI-ANDROGEN is Spironolactone
Synthetic steroid which is commonly used as a diuretic or as an Anti-androgen. -Potassium sparing diuretic. This on its own is a weak diuretic. Due to its anti-androgenic effect, it is common component in hormone therapy for male-to-female Transsexual and transgendered people and is also used for treating hair loss and acne in women....hmmm. Why then I wonder some women report the hair loss. It is marketed as a drug to treat acne.

Spironolactone inhibits the effects of aldosterone by competing for intracelluar aldosterone receptor. This increases the secretion of water and sodium, while decreasing the excretion of potassium. Spironolactone has a fairly slow onset of action, taking several days to develop and similarly the effect diminishes slowly.

ADVERSE REACTIONS TO SPIRONOLACTONE:
include menstrual irregularities and testicular atrophy, ataxia, erectile dysfunction , drowsiness and rashes*. A carcinogenic effect has been demonstrated in rats. Carcinogen is a term that refers to any substance or radiation which is an agent directly involved in the promotion of cancer or in faciliation of its propagation.

ATAXIA:
Steady and clumsy motion of the limbs or torso due to failure of the gross coordination of muscle movements. This often occurs when parts of the nervous system that control movement are damaged. People with ataxia experience a failure of muscle control in their arms and legs.

There is loads to consider on this front and lots of information available. I hope that this is helpful as you make your way through both understanding what some of your symptoms may be as well as informing/sharing your knowledge with a chosen medical practictioner.

Recommended for Adrenal Support:
Panthonene, B6, Zinc, magnesium and Vitamin C as they play a critical role in the optimal functioning of the adrenal gland and in the manufacture of adrenal hormones (which are suppressed taking Yasmin).

Take a look at:
Siberian and Panax Ginsengs

panthothenic acid

Ashwagandha
provides adrenal and immune support

Astralagus
in New Chapter Organic's multi and many other vitamins-used historically for strenghtening and regulating the immune system-as a tonic

Shisandra
improves immune function, increasing physical performance and endurance and for increasing resistance to disease and distress. Also possibly effective for increasing concentration due to the variety of lignans found in the fruit.

Maca-Peruvian Ginseng-
used for chronic fatigue syndrome, enhancing energy and stamina. In the female reproductive system, its use for enhancing fertility, regulating the menstrual cycle, treating common menopause symptoms and to increase libido. Its benefits have been known to the people of Peru for many generations.

Androgens are the precursor of all estrogens (the female sex hormones). the primary and most well known androgen is testosterone.

A subset of androgens, called adrenal androgens, includes any of 19-carbon steroids synthesized by the adrenal cortex, the outer portion of the adrenal gland that function as weak steroids or steroid precursors, including DHEA (dehydroepiandrosterone), DHEA-S (dehydroepiandrosterone), and androstenedione. Because Yasmin's ingredients have an anti-androgen effect that effect our adrenal glands-women with adrenal problems are advised not to take it.

Besides testesterone (which is responsible for sexual libido/function), other androgens include:

1) DHEA
(dehydroepiandrosterone: -a steroid hormone produced from cholesterol in the adrenal cortex which is the primary precursor of natural estrogens.

2) Androstenedione (Andro)-
an androgenic steroid, which is produced in the testes, adrenal cortex and ovaries*. While androstenediones are converted metabolically to testosterone and other androgens, they are also the parent structure of estrone. Estrone is an estrogenic hormone secreted by our ovaries. It is one of three estrogens which also include estriol and estradiol. Estrone is the least prevalent of the three hormones, estradiol being prevalent almost always in the female body, estriol being prevalent primarily during pregnancy.

3) Androstenediol:
the steroid metabolite that is thought to act as the main regulator of gonadotropin secretion-protein hormones secreted by gonadotrope cells of the pituitary gland. The two principle gonadotropins are LUTENIZING HORMONE (LH) and FOLLICLE STIMULATING HORMONE (FSH)-both of these are what are naturally release by our bodies on a monthly cycle are part of natural menstruation. The third human gonadotropin is human chorionic gonadotropin (hCG) produced by our placentas during pregnancy.

4) Androsterone:
a chemical by-product created during the breakdown of of androgens-or derived from progesterone -that also exerts minor masculnizsing effects, but with one seventh the intensity of testesterone.

5) DHT Dihydrotestosterone-
a metabolite of testosterone that is actually a more potent androgen in that it binds more strongly to androgen receptors.

FUNCTIONS OF ANDROGENS:
(keep in mind Yasmin has anti-androgenic properties):

Muscle mass:
Androgens promote the enlargement of skeletal muscle cells and probably act in a coordinated manner to enhance muscle function. (note: how many of us have experienced muscle fatigue and that Asthenia-was experienced by women in the Clinical Trials.

BRAIN:
Circulating levels of androgens can influence human behavior because some neurons are sensitive to steroid hormones. Androgen levels have been implicated in the regulation of human AGGRESSION and LIBIDO. Note, Yasmin's ingredients have anti-androgenic effects. That means essentially translates as suppressing the effects that androgen has in our bodies to regulate aggression and sexual libido...

Guest 36835-

Yasmin's diuretic is a potassium sparing diuretic. That's the difference. What that means is that while it flushes out fluids, it spares potassium-thus the risk of high potassium-and hyperkalemia a potentially fatal state!

To your question on research, as electrolytes get out of balance, so does muscle control. IE the number of women here who have suffered muscle twitchs from toe/feet to heart. In particular when the balance of magnesium and calcium is off-set, one experiences murmurs and muscle flacidity!

So have your magnesium, potassium and calcium levels checked pronto!

If you are experiencing palpitations, chest pain, see your Doctor or go to ER immediately. Have your potassium levels checked promptly to ensure that you have not developed Hyperkalemia (excess potassium) in your blood which is likely and happened to me becuase of the potassium sparing diuretic in Yasmin*. Hyperkalemia can be lethal and is extremely dangerous and a risk taking Yasmin.

Erykah-I haven't seen anyone whose tried/used St. john's Wort but would recommend instead having your hormone levels and your adrenal function tested? Oftentimes, after Yasmin, becuase of the diuretic flushing that occurs (constant peeing/urinating) it throws off our electrolyte and mineral balances in addition to that it suppresses our adrenal glands. I have found success with B vitamins (A B stress tab) or a whole food/bio-available Vitamin*. The whole food and bioavailability part is really important-because it is what makes it more accessible/useable by your body. Also-take a calcium and magnesium supplement if you find you are low on magnesium which is one of the minerals Yasmin's diuretic depletes*. I'm taking one that is equivalent ratios: 1:1-1000 of each because minerals compete with one another so taking a calcium that is higher will not give you the benefit of the magnesium. Low magnesium levels effects the health of all the muscles in our bodies-including the heat and if oftentimes what causes the murmurs/palps.

i have just read another article that states that potassium can interfere with b12's absorbability. for those of you that know, yasmin and yaz have a potassium sparing diuretic in them, meaning that you can get a build up of potassium....something to think about eh?........

I was only on the yasmin for 2 weeks but started having heart palpitaions and a bit of anxiety. I have been off for a week and a half now but I was in the ER 2 days ago due to the heart palpitations and maybe a small anxiety attack. My blood pressure was a little high(higher than normal for me, it was 131/97) I am usually low. They did an EKG, a chest x-ray and blood tests and the only thing they came up with was that my potassium levels were low which can cause heart palpitaions. The thing that I thought was strange was that they asked if I had been taking a diuretic. Yasmin has DRSP which is similar to Spironolatone (a potassium sparing diuretic)
They told me that if anything this would have spared the potassium but I am not convinced this seems very strange. This was the only medication I was on and I have never experienced heart palpitations or high blood pressure before.
Does anyone have any input about this?

Hello Silke and everyone
Former guest 18063 here, maybe I should call myself bitterRN? :) Anyway I hope you are all doing well. Sorry its been so long since I have written. I saw there were some questions about spironolactone what it is and if it could cause problems. Birth control pills are a combo of synthetic estrogen and progesterone. From what I have read on Yasmin the progesterone they use contains a hormone that acts like the diuretic spironolactone. Spironolactone is a potassium sparing diuretic, and Im not talking about an over the counter water pill to fight bloating, Im talking about a DRUG commonly used on patients with severe health problems like congestive heart failure and other diseases where they need a drug on a constant basis to combat swelling and water retention, which complicates the diseases they are having. (Quick example, I dont want to get too technical.) People with congestive heart failure have a weak heart that doesnt force blood through the body like a strong normal heart does. Therefore the blood does not circulate as it should causes all kinds of bad things including a lot of swelling especially in the ankles and even causes fluid in the lungs, which can quickly fill up with fluid causing respiratory distress (almost like drowning from the inside.) Drs put these patients on diuretics to keep the body constantly flushing fluids out to keep the lungs "dry" and so forth. Spironolactone is one such diuretic they use. Lasix is another. The difference between Lasix and Spiro is that Spiro holds on to the potassium in your body, while Lasix excretes it all out. So patients on Lasix frequently have to take a potassium supplement so that their potassium levels do not fall too low. My point here is not to scare you. They say the spiro level in Yasmin is very low compared to someone who is on the full drug. But I was shocked to see that they would put such a drug (I dont care how small amount it is.) In a birth control pill?!?!? Just to combat bloating? It is just my OPINION, but I dont see how this can be healthy to a normal healthy woman. I have noticed a lot of the side effects people mention in this website seem to be kinda related to dehydration. The muscle cramps you had, Silke, In my OPINION, I would think would be related to dehydration, being as that is a sign of severe dehydration, though I cannot say for sure if the spiro caused it. Probably even the drug company cant. All I know is that I was on ortho 777 for years without problems. Then all of a sudden I start taking yasmin and my whole life fell apart and I felt like I was dying...some days I wished I was dead. I looked at other birth control sites online, there is one where you can rate birth control meds on how well you liked it. I looked at yasmin and other birth control pills Yasmin had about a lot fewer people who liked it compared to the people who hated it. And while it is true, as my doctor said when someone does not like a drug or have a bad experience with it, they will write about it or post it on the site, but when someone likes the drug they do not write about it. This may be true, but I tried to find complaints about other birth control pills like ortho novum, etc. The only thing I found that people didnt like were things like, my period wasnt lighter, it didnt clear up my skin, it made me bloated, or gain weight. NOT serious things like chest pains, palpitations, severe headaches, severe depression, etc. Nor did any of the others have SO MANY symptoms!! Has anyone else found severe complaints about other bcp's? I would be curious to see them. So yes in my opinion I feel it is the spiro, because that is what is so different about this bcp compared to others, and NONE of the other bcp have this (spironolactone) component in them. I could be wrong though. As far as feeling better, I felt like I was going forward until this past week, feels two steps back again, my period is due next week too. It baffles my mind how a drug can hang in your system for soooo long, but I wonder if this bcp or just bcp pills in general have a cell binding action, so not only does it just circulate in your system and then metabolize out of the liver/kidneys as most drugs do, but binds to the cells in your body so that it takes longer (months) for your body to get rid of it? Maybe that is why my OB said it would take a few more CYLCLES to feel better. Maybe the drug is resurfacing during ovulation and we are shedding it with our cycle? I dont know Im just guessing. I will try to do more research on it, or ask my OB when I see her again. Gosh I'm so sorry I wrote too much again! I hope I kind of gave you a little more insight to spiro and why I was so PO'd when I found out it was in my bcp after 3 months of taking it and the OB didnt even bother to tell me it was in there when she put me on it. I'm so bitter! I wouldn't recommend Yasmin to my worst enemy!!!! To those of you who are on it and like it, just please be careful, if you notice a lot of the people on this website who were on it for years seemed to have symptoms come on either right away or years later and they tried to explain them away with stressful times in my life, or just tired, or some other reason other than the pill. I did it myself because I just didnt even realize it could be the birth control. My symptoms surely were not in the pamphlet. Oh and to the girl who is bulimic GUEST 18998 Yes vomiting can lessen or negate the effects of the pill. When you induce vomiting you dont know how much of the pill you have absorbed and how much you are throwing up. Chances are VERY good you are NOT getting the full dose of the birth control pill, being as that the pill takes a while to absorbed by the body, thats why they even like you to take it at the same time every day. Be careful to use another form of birth control on top of the pills (such as condoms) if you are mid pack now, and then I would explore other options for birth control (patch, IUD) something that is not ingested until and this is most important, you need to get help for your bulimia problem. This disease is not only a serious problem for your health, but I fear that if you are on Yasmin, which has the diruetic effect I have been talking about, and you are vomiting a lot, you are not only losing fluids and electrolytes from your bulimia, but also from the Yasmin, which can cause severe severe dehydration and electrolyte imbalance in your body and serious health consequences, so please seek help, and I really feel if you are on yasmin please consult your doctor and be honest with him or her about the bulemia, because I really feel its a VERY dangerous combination. Please also consider if you decide to quit a pack of yasmin before you have finished the active pills, that you must again use another form of birth control such as condoms to keep from getting pregnant. A "withdrawal" period is normal after stopping a pack of bcp suddenly, even if you recently had a period. If you need help finding a treatment center please let me know, but please get help. The lasting effects of an eating disorder are so not worth it in the end. I feel for you and hope to hear fromyou and everyone else soon! Thanks for listening. BitterRN

For all of you who are on Yasmin and think it's your miracle drug, I hope you never develop side effects because you will be in for the HUMBLING of your life. Imagine being a very successful well-respected person with no history of emotional or mental health problems developing an anxiety disorder after taking Yasmin and living each day of your life in fear. If you haven't researched it,many books refer to anxiety problems being medication-induced, particularly by
oral contraceptives and diuretics. In case you haven't figured it out, Drosperinone is a progesterone which is equivalent to the potassium sparing diuretic Sprionolactone and can cause vitamin depletion, severe electrolyte
imbalances and hence anxiety. We are simply not a bunch of women seeking a website to post our life's problems--we have friends for that! That's great if Yasmin works for you;I hope you never develop anxiety or depression...or better yet, die of a pulmonary embolus or stroke!

Oh boy. I took Yasmin for three weeks to try to shrink an endometrioma. The first day I took it I ended up in the ER with difficulty breathing - two days later I began to have tightness in my chest (I actually think it was that my already too big boobs got so big they strained my pectoral muscles) and was admitted with suspicion of a heart attack! While in the hospital they did every test imaginable on me and all the heart tests came out negative. I was without my Yasmin while in the hospital, but still felt awful and was peeing constantly even though I was clearly dehydrated (dark yellow urine). To make matters worse, they had me on the 'cardiac' diet - NO salt - which meant that my electrolytes were really getting screwed up.

From that time until /this/ week - two weeks after I stopped the Yasmin, I suffered severe dizziness, strange headaches, dilated veins in my breasts and chest, and severe anxiety. And we will not speak of the fact that the Yasmin made the spotting that was one reason I was taking the pill WORSE and, like many of the women on this list, it became dark brown and sticky. (and the fact that the Pill hadn't done its job led my gyno to send me for more invasive tests of my uterus - I don't mind ruling out things like endometrial cancer, but I had successful treatment with Provera some months ago and so I don't think I have anything /worse/ than endo, which is bad enough).

My research on this med showed that Yasmin is a potassium-sparing diuretic that flushes salt, magnesium and other important electrolytes from your system. Without adequate salt in your system, if you drink too much fluid (and many ladies here have been guzzling) you could actually get water intoxication and, if bad enough, /die/... if you drink Gatorade to help yourself, you may get too much potassium in your system (because Yasmin is potassium-sparing), which can cause palpitations and irregular heartbeat among other things. Be very very careful with this drug, ladies. I hear some of you saying you have been on it a year in spite of horrible effects - methinks maybe you should try a diaphragm? Good luck and peace!