Private hospital symptoms and conditions

I found this site as I want to read on the side effect of this Kenalog which was injected to my face by the doctor to reduce the size of two liquid cists (apparently only one injections). After the injection, I had my period which is only 15 days after my last period, which never happened to me as my cycle is always longer than 30 days and is very regular. Per the doctor, I thought the "cist" would be gone in few days. It did not and instead, I experienced rashes on my entire body and after one week, my ankle and knee was swollen and it was rather painful and I can hardly walk around for two days. Together with the swollen on the leg, the injection on my face is also swollen up and my face looked really in bad shape. I went back to the doctor and I was given one week of antibiotics to drain away the "infection".
Since the cist is still on my face and it really bother me as it is red and very itchy, though my face is not that swollen / puffy anymore. I came back and see the doctor again to have him cheked up on my face. He just gave me one month of antibiotic. I have no idea that having that injection would cause me so much troubles.
It is now more than a month after the injection, my face has a hole as that was injected with kenalog and the other cis on the face is still there. The worse thing is that the cist is is getting very itchy and it was not so before the injection. I am still patiently taking the antibiotic and promised to comeback and see the doctor after one month.
I still having pain on my join and reading your comments, I realized the pain is definitely associated with Kenalog.
I'd love to hear more from you on how things turn out. Thank you.

Singulair/Quinolinic acid - skin conditions and myalgia caused by eosinophils

Dear friends for this one I feel like Gomer Pyle "well g-o-o-l-l-l-y." I have been trying to solve the riddle as to whether Singulair might possibly cause skin conditions and myalgia. I found where a researcher actually injected himself with quinolinic acid to see if it caused a reaction from eosoniphils. So hypothetically if there were less than ideal metabolic or genetic conditions that cause the montelukast molecule to break up into a quinolinic acid by-product before it reached the liver then eosinophils will go to where-ever the quinolinic acid is. In the case of this researcher, the quinolinic acid caused skin inflamation conditions because he injected it into his arm.

This study could apply to any quinoline type drug that could break down into quinolinic acid. Now, we don't have proof whether Singulair can break down into quinolinic acid so the doctors won't buy this one as a fact. It is good, however, for a WHAT IF argument for those who would like to do a wait and see if Singulair caused the problem. This researchers eosinophil count took five weeks to drop back down to normal levels.

Clin Exp Med. 2006 Jun ;6 (2):60-4 16820992 (P,S,E,B) Is the L-tryptophan metabolite quinolinic acid responsible for eosinophilic fasciitis?

R Noakes, L Spelman, R Williamson
Qld Skin and Cancer Foundation, Greenslopes Private Hospital, Newdegate St, Greenslopes 4120, Qld, Australia. rnoakes@lagunacom.com.au
The eosinophilia-myalgia syndrome is accompanied by alterations in L-tryptophan metabolism with elevated levels of L-kynurenine and quinolinic acid having been recorded. It has been suggested that this is due to activation of indoleamine 2,3-dioxygenase by interferon-gamma. It is unknown whether these products of tryptophan metabolism play a role in the pathogenesis of this syndrome and the closely related condition of eosinophilic fasciitis. To explore this possibility, the principal author (RN) received a series of subcutaneous injections of quinolinic acid. A total of 1200 mg was administered over a 1-month period. Peripheral blood eosinophil counts were monitored and biopsies taken for H&E and immunohistochemical stains. Over the 1-month period the eosinophil count rose from 0.3x10(9)/l to 0.8x10(9)/l before falling to 0.4x10(9)/l approximately 5 weeks later. H&E sections showed a mixed infiltrate of eosinophils and neutrophils extending through the reticular dermis and septa of the panniculus. No deep fascia was obtained on biopsy. The immunohistochemical stain for transforming growth factor beta 1 showed staining of endothelial cells and dendritic cells. The interleukin-5 stain was negative. Our results suggest that quinolinic acid may play a role in cutaneous eosinophilic disorders.