Prometrium symptoms and conditions

I have taken Lurpron Depot 3.75mg June 11, 09. I am due another injection July 09,09. I had to get a prescription of prometrium 100mg from the OB/GYN because of the night sweats and hot flashes.Since the injection, I have had and currently experiencing migraine headaches in the frontal lobe and temporal lobe areas. I have slight pain in the temples. I am going to see a neurologist because I was told the lupron may cause brain bleed with people whom have pituitary cancer. I would like to know if the CoQ10 and red yeast rice interacts with Lupron.

I have PCOS, and was experiencing dysplasia of the endometrium. After some search, a doctor recommended the Mirena. This was November of 2008. The installation should have been a clue of things to come. I have never had children, and had a tipped uterus, and as a result they had to use the clamps that look like needle nose pliers to grab my cervix, and after 45 minutes of stuffing, got it in. It was excruciating. I was working out 6 days a week, 2 1/2 hours a day, and eating South Beach Phase 2- and had lost 80 lbs and had maintained for 1 year. I asked if it would in any way cause weight gain, and was told it would not. Within the first month my diet/exercise regimen failed, and despite working out 7 days a week and resuming Phase 1, I was gaining 10 lbs a month- which my Doctor would not discuss with me except to dismiss it. To make a long story short, after life threatening edema and bleeding 22 or 23 days straight and with my now discovered sensitivity to progesterone, I required a total abdominal hysterectomy to remove an enlarged, boggy, and fibroid riddled uterus. I am doing 200% better now, and I am sure there are some women the Mirena works well for, but I was not one of them, and I feel the Mirena actually endangered my life (that and the arrogant doctor who inserted it and told me to be patient. I had it in from 11/2005 to 7/2007- is that time enough?) Please, please,please. If something does not feel right, do not NO for an answer. I did not want children so I was okay with losing the ability to bear children, but having a TAH at 38 is a life change that most younger women would not want. Would I have had to have it anyway? Perhaps. But I could have been in a position to be navigator in my care rather than reactive as I was forced to be.

Thanks Ladies,
I was given the choice to have a Mirena placed this Friday
but was unsure because the Prometrium I'm taking 2 weeks on 2 weeks
off has made me dizzy, nausea,mood swings (can't stand myself) & headaches. But know after reading this, I will stick with the Prometrium and have a break every 2 weeks from the side effects, or should I say my family gets a break.

I was on Yasmin from November 2005 to February 2007. I didn't have a period until June 2007, and have only had 4 periods since then (and one was medically induced). I have been to a gynecologist and an endocrinologist. I have had a battery of blood tests done and all have come back normal. I have some more coming up.
Before going on Yasmin, my periods were relatively normal. I didn't have a "set your watch by it" kind of period, but I did have a period every single month (just different times during the month). While on Yasmin, I can't name specific side effects that I noticed. Looking back, breast tenderness increased (and continues), increased propensity to headaches and fatigue, and weight gain were all present. It is going off of it that has really messed up my system. My doctor originally thought I had PCOS, but blood tests have come back normal. I was even convinced, because since going off Yasmin, I have developed some of the classic symptoms. I am at a loss as to why my cycle has not returned to normal.
I am so frustrated, and while it is nice not to have periods, I want to know that I am okay. I am wondering if my being on Yasmin is still haunting me.
Has anyone else had difficulties for such an extended period after coming off of Yasmin?

basically, this was my experience with the paragard:
1. Dec 2004 - Paragard iud was placed post-partum after my 2nd daughter was born. i was breast-feeding, and had no noticeable symptoms until Nov 2005.
2. Nov 2005 - had my first period since my daughter was born. it was heavy and crampy, but i thought "i haven't had a period in 2 years, so this is the price i pay..."
3. Each period hence was heavy, long at 6-7 days, and cramps were intense. again, i just decided that i could manage.
By the end of 2006, my periods were so bad that my husband and i decided i had to see the doctor.
4. Jan 2007 - saw the doctor about removing the copper IUD. she said that the paragard should not be causing such bad symptoms, and since i was did not want to get pregnant, she decided we should try to control the symptoms with birth control pills and Prometrium. I did not want to try Prometrium since I was unsure of how I would react to the hormone. she believed that i might be suffering from severe pms, called PMDD. note that i loved and trusted this doctor - i had some complications during my 2 pregnancy, and some problems post-delivery, and she was attentive, personable, and caring. i was very comfortable and trusting, so i listened to her recommendations. i tried yaz, yasmin, and 2 other pills over the next 3-5 months, but was extremely nauseous and sick with all of them (plus break-thru bleeding).
5. Feb - September 2007: i started having pre-period symptoms of nausea, vomiting and/or diarrhea, abdominal cramps, severe fatigue. the first 2 months that i had these symptoms, they were so bad that i believed that i had an intestinal virus - same cramping, throwing up, and bad diarrhea, plus this was BEFORE my period. I then made the association between my symptoms, and the fact that they occurred 3-5 days before my period, and then they would subside about 3 days after my period started. my periods were still long with heavy bleeding.
6. September 2007 - was having same symptoms, but started 7-10 days before my period, and they were so bad that my husband had to take off from work to take care of our 2 girls each month (i stay home with them). i went back to the doctor during September, and was told to modify my diet (no white flour, sugar, low fat, high protein, lots of water) and to try some vitamin supplements since i didn't want more medications. she again recommended taking 100 mg Prometrium to help ease the symptoms. I asked to remove the IUD, again, and she said that "before she took out something that expensive, she wanted to make sure that something else was not wrong" - I was shocked at her statement, but agian I liked her and trusted her, so i went along for the sonogram.
7. October 2007 - In the meantime, I was desperate, so i took the vitamins and Prometrium, which sent me into what i can describe only as a psychotic episode. i had severe emotional outbursts, i was irrationally angry and irritable, and had absolutely zero patience. i am usually a smart girl, and in my normal "mental state" would have associated that the Prometrium had caused this severe reaction, but I was no where close to my normal state of mind, and i just thought that my physical symptoms were now affecting me mentally.
8. LAte Oct 2007 - BY this time I am so down and really ready to get my life back. I am still sick with nausea, diarrhea, vomiting, severe abdominal cramps, severe fatigue, and now my abdomen stays sore and tender through the whole month. FINALLY the doctor calls with the ultrasound results. she said that there were 2 small ovarian cysts - and i was relieved - i thought that FINALLY, we were getting somewhere - but in the next sentence she said that she didn;t think that they were responsible for my symptoms. i was deflated - and at such a loss of words. i listened to her tell me how she thought that i had IBS, and that she was going to refer me to a GI doctor. i know that IBS is a catch-all category of symptoms that some doctors throw on people they can;t diagnose. and remember, i was just a few days out from recovering from 1) having a severe personality reaction to a drug, and didn't know it was because of the Prometrium - i thought i was going mad, and 2) i was just getting over being sick before my period - AGAIN.
I finally called her back a few hours later and left a message with the nurse "since she doesn;t think that the cysts are causing the symptoms, could we please remove the copper IUD?" i never got a reply.
I called my niece who is an RN at a respected women's health center in NC and cried a lot and told her what was going on. she got me an appointment with a doctor there for mid nov 2007.
10. Mid Nov 2007 - tell the NC doctor my medical history, and she says "we need to get that IUD out". in less than 30seconds it is gone with minimal discomfort, 25% of the abdominal soreness and tenderness is gone within 24 hours of removal, and completely gone within a week. THIS WAS THE FIRST TIME IN MONTHS THAT MY TUMMY WAS NOT TENDER OR SORE!!!
i have a follow-up appointment for mid Jan 2008 with the NC doctor and possible placement of the Mirena
11. Nov 29, 2007 - have my first period in over a year where i am not sick etc - it is heavy and a bit crampy, but is shorter in duration.
12. mid dec 2007 - i start to suspect i may be pregnant, but think that we have been cautious, and my period is probably going to be irregular with all of the crap that has gone on
13. jan 5 2008 - yep - i'm pregnant!! but that was ok - we wanted another anyway.
14. jan 7, 2008 - catch the respiratory flu that has been going around and stay VERY sick for 4 weeks, and i just know that something is unusual - i can't eat i am so sick and am so weak that i shake whe i stand up - call a new local OB doctor and see them.
15. jan 30, 2008 - have miscarried the pregnancy
16. April 2008 - the new ob doctor places a mirena
17. first of may 2008 - my husband is asking if i feel ok, that he has seen similar but much less severe symptoms in my mood as when i was on the Prometrium. i have never had acne this severe on my face, neck and back - it actually hurts and i have some scarring even though i have not picked at it.
By the way, my new local OB told me that HE WILL NOT PLACE PARAGARD COPPER IUDS FOR HIS PATIENTS BECAUSE THEY WORK BY CAUSING INFLAMMATION IN THE UTERUS.
however, he also said that i shouldn't have any issues with the mirena, and now i am starting to wonder if i am going slightly mad...
i want my life back...
i now realize that there is a side effect to EVERYTHING that you put in your body...
i am terrified of getting pregnant right now even though a few months ago i was excited about this wonderful possibility...
i am now talking to a counselor to try to work out the events of this past year+ so i can move on...
i feel like my voice was NOT heard or even acknowledged...
the reality is that WE are ultimately responsible for our own well-being, both physical and mental, and that doctors do treat with preconceived notions about the way health should be and how medications and devices should work...they listen to pharmaceutical reps and not their patients...
i don;t know what to do about birth control now...i suspect the mirena is making me feel this way, but i am terrified of getting pregnant, i can't take birth control pills, and am hesitant to put any thing else in my body that is a chemical...however, i have no libido anymore (my poor wonderful husband) and i use to enjoy the closeness and intimacy of being with my husband...
i don't know how this affects your decision about the copper iud, but i just caution about 1) be careful with sex after the mirena is removed and 2) be mindful of anything that we eat or place in our body.
i do know that i could not find any other information from women who experienced my symptoms, but i find it very difficult to believe that i am the only one who experienced this.
lots of luck, and thank you for sharing your experience with the posting site! it has helped me make an informed decision about removing the mirena, and i hope that the information here will help you make an informed decision about the copper iud.

I made my appointment today to have my Mirena taken out in 2 days.
I have had similar symptoms, low libido, hair loss, and weight gain.
I have been on Weight Watchers since Jan. the same time I got my Mirena inserted and I am at the same weight. I am so frustrated with the weight and the other symptoms I just want it out.
But I did like not having to take a pill everyday. Is anyone considering having the Copper T inserted? It releases no hormones.
Just wondering.

Has anyone been off the ring for awhile and not able to have periods?

I still think a class action lawsuit should be filed and this product taken off of the market, i felt like i lost 3 years of my life on this medication!! Not to mention i put my husband and daughter thru hell!!

.Hi this is Sue again guest#33546. I am writing to follow up on my previous article, posted on 11/29/06. I saw my gynecologist on 12/1/06, after the prometrium he had me on failed to stop the bleeding. On December 4th I had surgery to stop extremely heavy bleeding and clots the size of a quarter that lasted 24 days. After speaking with Bristol Myers about my side effects, and them informing me this could continue until the drug was out of my system I decided a premarin injection probably would not work either, since the prometrium did not. I could not go on bleeding the way I was for several more months until this drug ran it's course and was out of my system. I was extremely tired, weak, and dizzy due to blood loss. I had a hysteroscopy, D and C , and an endometrial ablation also known as , performed to stop the bleeding. I was dehydrated and was given 5 bags of fluid in the hospital probably due to blood loss. During my pre op testing my blood pressure was elevated to 162 over 90. I have always had low blood pressure. They did an ekg and my heart rate was also elevated. Another side effect I failed to mention in my previous article was severe charley horse type cramping in my calves and feet while sleeping at night. The bleeding has lightened up to a brownish discharge now which is normal and can last for up to 2 weeks post-op. Besides informing Bristol Myers of my side effects I also contacted the FDA.

I received a kenalog injection by fluoroscopy for lower back pain at L5/S1 disc. After the injection my period was a week and a half late, once it started it hasn't stopped I have been bleeding heavily for 20 days now. I have always had normal cycles every 25 days and lasting 4 to 5 days. This is not normal for me, even after the birth of my 3 children my cycles returned to normal and I bled lighter and for less time than what I am now. I called and spoke to the nurse at the pain management clinic where I received the injection and she told me that she had never heard of that happening. She then went on to say possibly every 1 in 100 can have that side effect. My gynecologists nurse also said she had never heard of this. I started researching kenalog on line and every
article I found about this list menstrual irregularities. I had the pharmacist at my pharmacy print me the patient insert for kenalog 40 and it to lists menstrual irregularities. If I can find this information our so easily and the pharmacists are aware of the side effects then why aren't the doctors informing their patients. My gynecologist put me on 200mg. of prometrium which is a progesterone to try to stop the bleeding. Thirty pills total which I had to double up on the first week but they did not work so he told me to stop taking them. I am scheduled to see him tomorrow to possible try a
premarin injection which is estrogen to see if this stops the bleeding. I called and spoke with Bristol Myers concerning my side effects, and the nurse I spoke with told me kenalog
suppresses your adrenal system which controls cortisol and hormone production and it can take several months to get out of your system. I can not go on bleeding like this for several months it's already been 3 weeks with no end in sight. My only other option right now is a d and c. I am afraid to put any more shots or hormones in my body as it is messed up enough already. I have also been extremely week and tired, very dizzy, irritable, mood swings. no energy, sweats at night, shaky, and heart palpitations. I never had any of this before the injection. My only problem was back pain from an auto accident otherwise I've always been healthy. I know kenalog caused. I wish I would have been informed of the side effects first. It helped my back pain but it is not worth it for all the other problems that it caused. I told bristol myers when I spoke with them that they need to make sure that the medical professionals using their drug are aware of their side effects and that they inform their patients especially females, and she made a notation to follow through with my request. No one should have to go through this. I am so glad I found this website as I do not feel so alone now. I will write again and let you know how I made out at the gynecologists office. Sue

Mon. Oct. 9, 2006

I have been taking Prometrium for hyperplasia since 6-03. Before that I was taking Provera. I am also taking Synthroid ----but have seen quite a bit of thinning in my hair. Has anyone else experienced hair loss with Prometrium? I am 64 years young.

Prometrium may have been what I was given about 20 years ago. The shot for my disc herniation was injected directly into my spine. First one - an anesthesiologist shot directly in the spine above the injury and let gravity do the rest - helped a bit, but wore off quick. Last two shots - The Dr. used an x-ray m/c and dye to guide the injected fluid right there where the herniated goo lays on the sciatic nerve. It usually takes 4-5 days for the full effect - no sciatic pain - to take hold. Took care of the pain wonderfully, just "little reminders" every now and then. Those I can handle. But when I had the kenalog for allergies years ago, it was in my butt cheek. I've never had an indent and have never heard of this before! Grumpy, quick-tempered and a bit weepy would be good words to describe some side effects. Extreme tension - little things set me off that normally don't matter at all. Screaming all day - I can definitely identify with that feeling after a shot. Not having that this time - I have prayed for that not to happen this time - As far as a waiver - yes. They never describe fully what the side effects are. When I was young and taking them for allergies - my doctor said there were no side effects. Well, I fell into depression a while after and began taking Zoloft. I eventually found an article in a magazine which confirmed that corticosteroids deplete serotonin in the brain - hence - I am still taking anti-d's......Just take it easy and try not to move wrong or overdo it after the shot - I think I got to excited at feeling good and may have reinjured it. I hope this is the last one.

I am a 35 y.o. mother of two. A year and a half after having my second child, I was diagnosed with PCOS (January of 2004) after telling my doctor that I was suffering from cystic acne, very irregular periods (if i got one at all), hair developing on my chin and upper lip, etc. My doctor ordered some blood tests and a sonogram and sure enough....cysts all over the place! Since I have had problems with hormone-induced birth control methods in the past, my GYN started me on Prometrium to help get my cycle regulated and to "ease" my body into taking the pill before starting me on Yasmin. I began taking Yasmin about 6 months later as my doc raved about this being an excellent treatment for women with my condition. HE COULD NOT HAVE BEEN MORE WRONG!!!! While Yasmin did away with my acne and regulated my periods, the side effects that I suffered far outweighed any positive affects it could have had and were far worse than any side effects I'd ever experienced on other forms of the pill. I suffered with depression, uncontrolled (not to mention untimely) bouts of anger/rage/crying, severe acid reflux, ZERO libido (much to both my and my husbands dismay), vaginal dryness, dry eyes and nasal membranes, severe night sweats, respiratory problems (I was drying out which was irritating my lungs and giving me false asthma symptoms and I've never had asthma), very dry skin, "phantom" abdominal cramping, unexplained memory loss, insomnia (aye yaye yaye! the sleepness nights), anxiety, severe headaches which increased in both frequency and intensity as time went on, frequent leg and back cramping, intermittent and unexplained bloating and water retention (isn't this supposed to be a diuretic?)....you name it, and I've pretty much experienced it over the past 6 months. I even went to see my regular doctor explaining my symptoms. He ordered a series of blood tests, potassium and calcium tests, liver enzymes, etc., etc., etc....everything came back NORMAL! I though I was going crazy! After on the first 3 months taking the pill I went back to see my GYN to tell him that something just wasn't quite right and that I think he should put me on something else. His response...."Give it time. Your hormones have to level out. This is one of the most successful pills out there for your problem...." blah, blah, blah, yada, yada, yada. I listened (like an idiot) and stayed on it hoping to "level out" at some point, which never happened. My turning point was in January of this year, when in an uncontrolled bout of rage, I exited my car at a red light to confront a male driver who had been honking the horn behind me (apparently I was supposed to drive through it) and then proceeded to call me a stupid b*&%h out of his car window, at which point I ran over to his car window and dared him to get out and say it again!! He promptly rolled up his window and sped through the red light. I got back into my car, drove home and sat in my driveway and cried for nearly a half hour out of sheer exasperated frustration. I threw away the remaining pills, called my GYN and told him he was a quack and could kiss my a$$ and have never looked back. I've only been off the pill since mid-January, but I've already seen a drastic difference in the symptoms that I mentioned earlier and some have gone away all together. I'm still having problems with the anxiety and the anger/crying bouts, but not as often and not as severe in intensity. Ladies trust your bodies....if you feel that something is wrong, it is! No one knows your body like you do so don't be afraid to tell your doctor that you want something different.....they work for you, not the other way around. As far as a class action suit goes, someone please let me know as soon as one gets started and I am so there!!! This pill is a danger to women and needs to be taken off the market all together. Please feel free to email with any information on upcoming litigation or if you have any questions.