Prostate cancer symptoms and conditions

Toprol XL I just started a week ago as the medicals cant get my blood pressure under control. I also take Lisinopril at 40mgs. Was told at 40mgs. of Lisinopril thats the highest dose there is (which I found is a lie from a lady I know when she told me her husband takes lisinopril XL or along those lines). Meantime..on Toprol..I cant figure how to describe it other than..when the medicals decided not to deal with my medical issues and gave me 1st Zoloft then Prozac. I had such bad reactions from them I told the medicals to deal with my medical problems dont blow me off with shrink pills! Meaning...I have the same reaction with Toprol as I did with Zoloft and Prozac...emotional, cant focus or concentrate..cant sit still..I look like crap because I cant sleep more than 5 hours or so...
Im already plump from middle aged (and I use to be bone thin at one time)..Im hungry..and yet I look and smell food and I about gag...Bits and pieces at times I can get down me though..Toast, yogurt, that kind of thing. IM tired and weak too...It takes everything I have in me just to peddle my bike 3 miles around the housing area I live. After that, I flop..
I have to pee every 2 mins too...Bad enough the pressure from fibroids on the bladder..Medicals say..Dah..they will shrink when you are finally post menopausal. ( I would love to tell that line of BS to the doctors with breast cancer or prostate cancer..see how they like it).
I am trying to give the benefit of the doubt here..give it time and see if these side effects wear off in time...But as it stands...
Between this crap and the migraine medications..IM sick and tired of not being heard/taken seriously by the medical community...Getting so Im all for alternative medicine and just let the medical doctors/FNP-C and specialists kiss my backside..

My husband was diagnosed with prostate cancer in 2005
the doctor did the 8 weeks radiation treatment,,,,,,it has been a mess ever since,,,,,,,,,his numbers are still going up and his dr. gives him a shot of lupron every 3 mos.........it only brings his numbers down,,,,,,, i know if the numbers keep going up they did not get all of the cancer.....anyone else going through this.......thanks

I am a male 61 who had 2 years of lupron for prostate cancer. It has been a little over 6 years since my last treatment and I am still suffering from the side effects. I have headaches 24/7 and am very sensitive to heat. I have ended up in the hospital twice due to extreme heat. My psa is slowing coming back and I may have to have lupron again, God help me! I also suffer from depression, maybe from being ill for so long, I also have occasional bouts with nausea.

I am in month 4 of a 4 month Lupron shot that my doctor gave to prepare for surgery. I was told I might get hot flashes, loss of libido, increased urinary symptoms for a few weeks. No one said anything and there was absolutely nothing in all the drug leaflets they gave me that would have prepared me for the the horror story that my life was about to become. As if having cancer was not bad enough.Since day 2 I have suffered so many bad side effects that I have lost count. The worst is insomnia and nothing has helped including high doses of Ambien. They suggested Lunesta but my health insurance company balked and even if they had said yes, my co-payment would be unaffordable. This stuff is more expensive than gold. I am exhausted all the time. I have terrible memory problems that are so bad that I can be talking to some I know really well and not remember their name. I am unable to concentrate on anything, my mood swings are unbelievable, I feel mentally disoriented and dissociated all the time, high blood pressure, racing pulse, high blood sugar, hot flashes, raging night sweats, dizziness, bad balance. The side effects that I can handle include nausea, headaches, diarrhea, joint and muscle pain. I am supposed to be on Lupron for 2 years. The only difference I see with my Lupron experience and others here is that my gender is MALE and I have early stage prostate cancer. Being male, my other serious Lupron side effect is complete impotence which is going to go on for a long while due to the radiation. I had radioactive seed implants into my prostate gland done a week ago and I have to follow this with 5 weeks of beam radiation. Lupron seems to be an equal opportunity drug. Lupron has messed me up so badly that for the past 5 weeks I have been off work on disability status with no chance of going back for at least a month and my Dr thinks that may be optimistic. No one seems to know how long it will take to get back to some kind of normal. I just could not function at work and ended up in my doctors office having a complete emotional meltdown. I would caution anyone, male or female, to consider Lupron very carefully before having it.

Lupron is a dangerous drug. There are over 10,000 adverse events reported to the FDA about this horrible drug. It causes significant bone density loss and many, many other horrible long lasting side effects. Check out the FDA website for yourself. This drug controls the release of estrogen, which is vital for all body functions and brings your estrogen levels dangerously low. Check out the Center for Endometriosis Care in GA or The Center for Advanced Laparoscopic Surgery in NY or Dr. David B. Redwine in Bend, Oregon. This drug was originally approved in 1985 for the treatment of advanced prostate cancer. It is a highly toxic drug!!

One year after my shot of Lupron I have severe joint and muscle pain and breast tenderness and pain. I am a male who had the Lupron in concert with radiation therapy for Prostate Cancer. My MDs suggest the joint and muscle pain is a result of arthritis, and a mammogram is recommended for the breast swelling and pain. Any males out there with similar symptoms?
PB

I started using lipitor from my doctor, it lowered my cholesterol all around but I started to have lower back pains. At first I thought it might be prostate cancer, but after having to MRI's done they found no cancer, thank god. But I went to an orthopedic surgeon to see what the problem was. He looked at the mri's and saw lower dics hitting my nerve endings. He also thought that it might be muscle problems so he gave me 3 epidurals and that helped for a while took away about 50% of my pain, but I still have the pain, It is hard for me to get comfortable when I sit or even when I am sleeping. I don't want to think that it is the lipitor that is doing it to me but after talking with others I feel it is time to talk to my doctor about it. My doctor said that lipitor is the safest one that will do very little harm to my liver. I am not a doctor so I would not know.. My cholesterol level was 246 at one time now it is 175. I am now facing possible spine fusion to help correct my disc problem. But will also ask doctor to prescribe something else.

Alan

We have all been saying that our issues regard not being informed about all of the possible side effects. And, we know that Singulair works well for some people. Nobody wants to take a good drug away from those for which it probably performs miracles. People who have toxic side effects have a right to know up front.

My observations about montelukast's chemical structure are either general or not quite 100% correct or could be quite vague - so forgive me. I do not claim to be good at organic chemistry. But from doing a little work, I have come up with some observations.

1. It would seem to me that montelukast might work quite well for people who have developed mold category related asthma. I observed that chloroquinolin, a component of montelukast, is a good fungicide effective against Aspergillus, Alternaria, Cladosporium, Penicillium and Candida. Dust mites can only digest if helped by aspergillus so they go into the mold category. Molds produce millions of spores so anyone who lives in contact with mold would be chronically sick from their presence. Then people get hypersensitized to that.

I am probably wrong but I could imagine that montelukast is: 1) a ligand that binds to an empty cysLT1 receptor for a period of time 2) 7-chloroquinolin-2-yl which either acts intact or breaks down into a quinoline fungicide so that it kills the chronic mold/fungus infection and 3) a sulphur/methyl anti-inflammatory component that tells the t-cells that they are not needed so they will die. Wow, that would be great for mold asthma if it was completely non-toxic. It would be also great under controlled circumstances for many people who are mold-miserable. If I am wrong, I better go out into my garage and start inventing such a drug.

This is my visualization to try to explain the side effects of neurotoxicity. So adverse reactions could be to the quinoline component as an allergic reaction or dose related so that it just built up to a toxic level over time. There are many signs that t-cell populations are significantly reduced by montelukast. The fact that the Italians can do it in the test tube might be that it's a chemical component of montelukast designed to cause the t-cells to die.

Montelukast is a large molecule so Artie says it cannot penetrate the blood brain barrier. That would be an argument if nobody was complaining about neuro-psychiatric side effects. The neuro-psychiatric side effects are identical to quinoline and quinolones. When I read about Lariam, it just sounds like a more extreme version of Singulair side effects. Chloroquinolins were used before they invented Lariam, which is stronger. The malaria Plasmodiums became immune. Hallucinations, anxiety, depression, suicidal thoughts are completely consistent in all of the quinoline/quinolones. If montelukast breaks into sub-molecules then quinolines easily penetrate the blood brain barrier.

I find clinical evidence that montelukast may act as more than more molecule. And, that there is a rational for the existence of the chloroquinolin and evidence that it may be the source of toxicity.

I am glad to risk being called crazy. That is what the internet is for. We can present our ideas and discuss. So, just take this with a grain of salt. If I am close to the truth, this post will find it's proper home.

I am a 68 year old male with prostate cancer that has spread. My first Lupron shot kept the PSA down for more than a year, but the effects were so terrible I refused more until a bone scan showed my cancer had spread all over and my PSA went thru the roof. With 2nd and subsequent shots my doctor had me take Casodex pills for 10 days and drink soy milk to kept down hot flashes and night sweats (yes, men can have them too). With this regimen I have had absolutely no side effects. I also now take soy pills instead of drinking the milk.

Not sure about Casodex for women (I had pills left over from prostate cancer treatment) so check with your doctor. But soy pills are designed for post-menopausal women and sold at drug stores.

My husband and I found out he had Meatastic prostate cancer 13 months ago..We went to the doctor because his lymph glands were hudge.. He has been on the Lupron injections ever since.. He had really bad hot flashes for the 1st few months but that has past, but now he is very moody and angry for no reason.. He yells and gets angry over the littlest things i think he is going crazy and he is driving me nuts, he has no desire for me and is rude and acts like he don't even like me sometimes.. it is torture to me..He has depression he doesn't enjoy anything like he use to.. whenever we go try to have fun he gets all stressed and makes the fun turn into miserable..He acts as if he has no problems..He has some big rashes on his legs and crack and I am pretty sure it is from the Lupron shot also.. he has a little aches and pains. Very tired all the time..just about a week ago we found out the Lupron shot is not working very well anymore, his psa level went up to a 15..I am thankful for the shot because i know it has saved him some time to be here.. I love him so much, but the way he is now has caused me to feel like he is a grouchy roommate on his period 24/7.. There is other things like casodex to take but i heard it does not work as well as the Lupron..Hopefully one of these days they can find something that works even better then Lupron without the side affects..The lupron Shot has helped many people live longer, but what about the quality of life he is miserable but I am sure he rather be alive and miserable.. Good luck to everyone with the Lupron shot, it is a trying time when they or you go through these changes and do not understand why you feel negative and unhappy..

I started IVF and Lupron was my first injection I had to take along with birth control pills. I feel like I've experienced every side effect possible and it is making me crazy! My vision is blurred, I can't even focus long enough to read a book. Migraines, night sweats, hot flashes and I feel on edge all the time like I may freak out at any moment. Very moody thank goodness only ten more days!

55 year old male and used to be in excellent condition. I had radiation and Lupron Depot injections for prostate cancer and even though my PSA is down to .032, the hot flashes, joint pain, weakness, weight gain and atrial fibrillation caused by Lupron sucks. Now I am on medication for the a fib and it's really horrible.

I read up on Lupron and was very hesitant in taking the shot, However, my doctor convinced me that it would be helpful with my Endo which is a stage 4. My doctor said well any medicine is like a restaurant if the side effects are bad then everyone knows just like if you get bad service.
Well I got my first shot about a month ago and I think I should have listened to myself, I traded one pain for a ton of others.
I have severe depression at times and the bone pain is almost more than I can bare. I live on Advil to keep the pain under control. I can barely get out of bed in the morning b/c I hurt so bad and I can barely walk. I am losing hair and it is thinning out horribly. I too have put on weight with regular exercise and watching my diet.
I get heart palpitations to where my heart feels like it is going to jump out of my chest and this is the first month. I am afraid of what the next month will bring. I am only 35 and didn't want to get a hysterectomy.

In 10/2001 I was diagnosed with Prostate Cancer and my MD prescribed a Lupron 3 month Injection to reduce the size of my prostate prior to radiation seed therapy. l started having the following symptons immediatetly frequent hot flashes which disrupted my sleeping at night from 4 to 6 times per night and which lasted for 9 months, I was no longer able to achieve an erection, although immediately prior I was able to have sex with an orgasm. I loss muscle and gained weight. Seven years have past and during that time I developed a heart arthymia which I was hospitalised for all this despite forcing myself to stay physically active, by walking, lifting weights and doing manual labor. I have never been able to regain my strength despite my exercising. I am now suffering from an undiagnosed skin disease and low blood platelets which my doctor thinks is an auto immune problem. This drug has had a severe impact on my well being and I tell all my male friends that if they ever have prostate issues to avoid hormone therapy at all cost.

I underwent prostate cancer IMRT radiation in 2005. As part of the treatment, I was given three four month doses of Lupron Depot. Men who get this drug experience a reduction of testosterone, wright gain, hot flashes, and sometime depression. I had all of those.

Toward the end of 2005, about two months after my last injection, I noticed a tingling, sometimes burning sensation in my right fool near the toes. Over the past year or so, the sensation has spread to my other foot and sometimes up my leg.

My symptoms have all the earmarks of peripheral neuropathy. So far, my motor functions are okay, and I have been checked for diabetes, and found not to have it, which is a relief.

I did have an attack of Bell's Palsy back in 1973, and it was treated with heat and cortisone. It never came back. I see from some of the web sites that there is a connection between Bell's Palsy and peripheral neuropathy, and and also a connection with Lupron and peripheral neuropathy.

I realize there is little I can do about it, but I think the physicians who prescribe Lupron for prostate cancer should also make their patients aware of this possible side effect.

I have been taking proscar as treatment for my prostate cancer for 2 years now and side affects that come and go are extreme dry skin on my eyelids and corners of my mouth. Extreme dry skin on my testicle sac.
Some fatigue and some depression. My chest hair is pretty much gone.

I have taken Lupron for 2 months for prostate cancer and the worst side effect has been dry mouth, which has become painful and promoting unhealthy gums and teeth.

I am on Lisinopril 10mg I break the tab in half take it morn and night, also I am on Hydrochlorot 12.5mg once a day.
I have been having a cough, dizzyness, tiredness, knee pain and I have no control of wetting myself when I cough. for some time now. I have been on this stuff for a year. I went to the Doctor the 14th of Nov. only to find that my Triglycerides are out of the roof my Cholesterol is up and I have high blood sugar. My blood preasure is good though.
I watch what I eat very closley. I am a bit over weight 60#'s.
I have been on the web for 3 hours now checking out these problems well Hydrochlorot causes the Triglycerides, Cholesttrol and the blood sugar to go up. Then I find this web site stating all the problems that Lisinopril causes I am having some of the same problems as the rest of you.
I am not going to take any more of this poison. I am going to go the natural way. I found on www.rxomega3.com some information about Lowering Triglycerides the stuff is called OMACOR (omega-3-acid ethyl esters) it is FDA approved which means nothing to me. Your Doctor can prescribe it for you.
Thank you for all the information you all have shared about this drug. My husband and I do alot of the natural ways in the first place but I feel I was scared into taking these drugs.
I am just going to put my trust in the Lord from now on he is the doctor and the healer. He healed my Husband of Mastatic Prostate Cancer this year.
If you want to email me with any comments please feel free to do so my email is ******

I am using Lupron for treament of prostate cancer. I have had radiation and radioactive seeds. I get hot flashes, joint pain is almost unbearable and skips around all over my body. I am tired most of the time and today, it even settled in my hands and wrists to where I can't pick up a glass. I am supposed to be on this medication for 1 to 2 years. I don't know if it is worth it or not.

Seem to have blurred visionat times since using Flomax, doesn't seem to helpflow that much, had seed therapy for prostate cancer 2 years ago, my problem is frequency of having to urinate, also noticed muscle pains in knees etc, lack of energy etc?

I was diagnosed with prostate cancer in 2004. Began taking Lupron Depot in 3 month intervals for 13 months because of the advanced stage of the cancer before radiation treatment. Almost immediately, side effects occurred, to wit: hot flashes, insomnia, mood swings, aggitation, severe headaches, ringing in the ears, dizziness, muscle and joint pain--particular in the neck, shoulders, elbows, knees and ankles--anxiety and panic attacks, bewilderment, night and day sweats for no apparent reason, high blood pressure and incidents of weakness accompanied by unexplainable general feeling of being ill. Ceased taking the Lupron in fall of 2004. I am still experiencing most (not all) of the side effects. Blood tests have shown the presence of the drug in amounts higher than expected still in my body however continuing to diminish. Good luck! Being strong willed is a must to endure many of the side effects delineated here. I anticipate I have 2 or 3 more years of hell before the Lupron dissipates from my body. "And this will pass..."

severe chst pains -more than tingling-nocturnal; wakeups 2-3-4 times, occasionally accompanied by hot flashes - been going on for 19 months since twice injected pre-prostate cancer cryosurgery op - I'm going on 82, great physical shape Ret USAF Col, widowed, - pains occur nightly and daytime w/o warning-triggered when I lay on right side in bed - 19 months??

Injected pre-Cryosurgery for prostate cancer (twice in the butt) April '05 and STILL experience serious, hurtful pains, wakes-me-up several times nocturnally, during daytime also, pains across chest, triggered if I lay on right side in bed - more than mere tingling, pains are sharp across chest-breasts - going on 19 months?!?

Is male breast "enlargement" and tenderness a side effect of Lupron? Only the right breast has been affected. It has been about a year since the patient had taken Lupron in connection with radiation for prostate cancer.

I have been getting DEPO LUPRON 11.25 every 3 month for
prostate cancer for the last 15 months and I have swelling of my legs can this be one of it's side effects?