Quinolone antibiotic symptoms and conditions

I took Levaquin for a sinus infection March 26th... 5 doses of 750 mg. I felt slightly better initially but that lasted only a day. I think it was prescribed wrongly, I had a virus and was getting over it... not a bacterial infection. The problems started about a week after the 5 day course ended. I ended up in the ER feeling like I was going to die, some strangeness in my breathing and feeling as if I was having a stroke... like I was going to pass out. They found nothing wrong except an elevated blood pressure and did a d-dimer to see if it could be an embolism (at my insistence, I had no idea this could be from levaquin and thought I was having a stroke. After the ER visit, I just felt like I had the flu, but I didn't... weak, extremely tired with some muscle aches ... two weeks out I had a lot of pain in both legs, like charlie horses that didn't go away... that lasted several days to a week... the weird depersonalization and the anxiety has been intense throughout. Constipation (never ever had it before this drug) started about a month out from taking it. I still feel pain in my legs from time to time and a feeling like there is a tight band across the top of my left foot... like when you tie your shoe too tight and need to loosen the shoe strings, but I am not wearing shoes.

I have been taking this Leviquin for 4 days. I have had severe cramps in my calves and feet in the middle of the night. So bad that I get up and try to step em' off but to no avail. My muscles hurt so bad in my legs arms and I have been very sick to my stomach. Do these things go away? I am not taking one more of those pills. I would rather have sinus and bronchitis problems than deal with these horrific side effects!! Any feed back?

I have had pain in my knees and legs after taking levaquin for pneumonia for 10 days. I am weak. It is hard to get up and down and very painful with steps of any kind. I am very depressed from the pain and inability to find anything that will help. I have been to an orthopedic doctor and had X-RAYS. Just given anti-inflammatory. No tendon or obvious reasons for pain. What do you do now? Who do you go to for help? In
the mean time, my breathing at night has gotten worse again.

I was hospitalized with a severe kidney infection, later to be told it was e-coli. After several days of intravenous antibiotics along with prednisone in my IV to help manage terrific arthritis pain, I came home from the hospital with a prescription of levaquin, prednisone and something for my stomach that I could have gotten over the counter. I have progressively gotten sicker on my stomach, had severe attacks 3 to 5 times a day, headaches, extreme fatigue and weakness. Worst of all were the crazy thoughts when I woke up partly due to nightmares and partly to just not feeling myself and having a feeling of loss of control of all my emotions. I told my husband I believe I was going into a depression. After stumbling onto this site, I threw the 5 remaining levaquin in the trash and thank God that I found all the information I have today on this POISON. I agree with many that the side effects far outweigh any good this antibiotic has done for me. I continue to be very sick and weak. I just hope when I wake tomorrow this mess is out of my system for good.

I am a 57 year old male, who is in very good shape and active playing sports. I had a bad cold and had just finished a 3 day "burst" of prednisone per my asthma specialist. I am supposed to keep it on hand and take it if my usual meds and "rescue" inhaler are not working, and I feel that I am going into an infection (asthmatic bronchitis). The steroid treatment did not work, so I saw a doctor who prescribed Levaquin (with a coupon for $15 off) - for 10 days. The pharmacist remarked that they had seen a LOT of these coupons and that the drug reps must be doing their jobs. I read the warnings which noted that "in rare instances, ...". after I got home. Since I was leaving town immediately and did not have time to change meds, I took the Levaquin. I have suffered leg cramps for over three weeks now and don't know when or if they will disappear. The cramps appear in my hamstrings, groin, thighs, and calf muscles. They are debilitating. Sometimes I can barely walk. I am no longer able to play racquetball. I try to stretch out and warm up thoroughly before physical activity, but the cramps still appear in one muscle group or more - then I stop immediately.

Update: I took Levaquin 2 months ago, stopping after 7 daily doses of 500mg for an upper and lower RI. I did not have the extreme reaction to it that others here suffered. I had general fatigue, brain fog, loss of appetite, dizziness and tight joints. I had always exercised regularly prior to Levaquin. I also had a sudden onset of bloating and inability to digest food. Doc said Levaquin wouldn't cause those symptoms. It's hard to tell if it was the Levaquin, but...

Now 2 months after my last Levaquin dose, my joints seem OK, I can exercise, although I don't push it too hard since that can aggravate any joint damage done by L, the brain fog is better, and the digestion is still a problem sometimes.

Levaquin symptoms can appear months after the last dose, so I am being vigilant.

God bless everyone here who has had horrible experiences with Levaquin and I hope that your bodies will heal as the months go by. I will be posting updates in the future.

I was prescribed Avelox for pneumonia, which I had a severe reaction to. I was driving in my car with my kids and suddenly didn't know where I was. I was so confused and pulled the car over and vomited. I rushed home and was launched into a full-fledged panic attack. I was then given Levaquin and I was fine with it other than some mild malaise and a little dizziness for the 7 days of 750mg, but my symptoms just came back soon after and I developed a sinus infection and was put back on the Levaquin. I took one 250mg pill yesterday and had the same thing happen, severe fatigue, weakness and numbness in my hands and arms, dizziness, confusion, panic attacks, blurred vision and severe diarrhea. I felt floaty and out of it for the rest of the day and night. I woke up this morning and I feel much better, other than some left over anxiety about taking the prescription. THE GOOD NEWS is that my symptoms are gone now that the antibiotic has been metabolized and secreted from my body. I did see some floaters in the shower today, but I believe they were because I strained my eyes when looking to far to the right. I drank 2 glasses of wine to help with the increased heart rate and insomnia that the drug caused--worked well!! I would never, ever take this antibiotic again.

Im not wanting to scare any of you, but my reaction to this family of antibiotics happened in Spring 2002. I took one dose of this quinolone antibiotic for a sinus infection and was in the ER four hours later. After taking the medication, I felt very fatigued and lay down on the couch, I woke up a few minutes later feeling like I was falling, and my heart sustained 170+ beats per minute heart palpitations for several hours. The last thing I remember was calling 911 because I was home alone and knew something awful was happening. The ENT's said that they had never seen anything like it. I experienced horrific anxiety attacks for weeks afterward. Keep in mind I had been a very healthy gal before and had never experienced any type of health problems. I now see a rheumatologist, a neurologist and a gastroenterologist. I have been diagnosed with MCTD (Multiple connective tissue disorder) a Lupus like illness. My neurologist says that my central nervous system was damaged in the reaction as well. He also says that physicians are grossly misinformed about this family of antibiotics, and in his opinion, anyone who prescribes them for anything less than a life threatening condition is committing medical malpractice. I agree wholeheartedly since my life will never be the same.

In my case, Cipro tablets were prescribed for a potential prostate infection. The first dose was taken on 12/12/07. While taking this medication, I experienced "pens and needles" and shooting pains all over my body, leg pains behind my knees, right groin swelling to the point I could barely walk, and chest discomfort just below the sternum. The chest discomfort started after the second dose. My use of this drug was discontinued on about 12/17/07 (after 6 doses). I threw it away. Read the label BEFORE you start this medication. It's quite alarming after the fact.

I let my physician know about my problems with the Cipro and he then prescribed Levaquin, 500 mg, which is the same class of antibiotic. This was confusing to me later since I told them about the problems with Cipro. The doctor knows best...right- so I took 1 Levaquin per day from 12/21/07 until 12/26/07, again about 6 doses. My symptoms re-appeared after about the third day. Pen and needle pains re-occurred although they never entirely went away from the Cipro, severe swelling and tendon pain behind knees- especially the left knee, some chest discomfort, swelling in the armpits, and groin area. Swelling sensations were most prevalent behind both knees and the armpits. Shooting pains also occurred everywhere in my body, especially in the arms and legs. Shooting pains also occurred in my head and jaw with no warning but were less severe. The bottoms of my feet also hurt at times. Sleep was difficult to come by so extreme fatigue set in. I have been off the Levaquin now since 12/26/07 (5 days) and still have some shooting pains but some of the swelling has subsided. The symptoms have reduced but not disappeared entirely. I will never take a quinolone antibiotic again. My suggestion to others is to file an Adverse Drug Reaction report with FDA on their Medwatch website.

I again saw the physician on 12/27/07 and he said that it's "possible" I could be having a rare side effect. Another physician I know said I was having some type of hypersensitivity to the medication but that he had never come across such a case in his practice. Just my luck.