October 13th
2008
9:21 AM
husband and brother in law both diagnosed with Parkinson's disease. dear friend's husband diagnosed with Parkinson's 3 months later . all had been on lipitor for 2-4 yrs. brother in law has died--diagnosis changed prior to death from Parkinson's to Parkinson's with lewy bodies, to Lewy body dementia to frontotemporal lobe dementia (despite NO family history of this disease entity). there are SO many metabolic substrates whose pathways are interrupted by statins--pathways to isoprenoid metabolism resulting in among many other results, a decrease in glutathione reductase; a decrease in production of coenzyme Q10; decrease in dolichol, the lipid consittuting the largest % of fats making up the substantia nigra in the brain (area diseased in Parkinson's ). and lipids constitute the substance that makes up the mylein sheath surrounding nerves, and the largest % of the dry weight content of the brain.
Tremors were the first symptoms. then non swinging arm while walking, flat affect, rigidity of muscles. all symptoms of Parkinson's...
March 3th
2008
7:28 PM
I had been taking Lipitor for well over six years to help lower my Cholesterol count with no know side affects. A problem developed about two and a half years ago with nerve damage that gave me excruciating pain in my shoulder and arm. After an MRI and three cortisone shots I was referred to a neurologist for help. He had no idea what was causing the problem.
About six months after many doctors could do nothing for me, and referring me to a physical therapist, my wife showed me a story in a magazine, which I can no longer find, that talked about problems with Lipitor that had not been properly documented. The article talked about exactly the side effects I was having. The article said there was a problem with nerve damage. It had been well documented that some people had muscle problems, but it was not know there could also be a problem with nerve pain.
I contacted my doctor and stopped taking Lipitor. Two months later, the pain just disappeared. The very day the pain ceased, I had a visit from a good friend of mine who is a Radiologist and who had studied Lipitor because of a problem he was having.
He explained that Lipitor was doing the job it was supposed to do, namely keeping the liver from producing all fats. The problem I was having was that I had injured a nerve and Lipitor was keeping the liver from producing a particular fat needed to help heal that nerve. It seems that the myelin sheath around the nerve needs that fat to help the nerve heal itself, and Lipitor was preventing the production of that particular fat.
Once I quit taking Lipitor it took about two months for the healing fat production to do it's thing. Recovery of the nerves in that arm has been very slow, but they do seem to be healing now.
I thought this was such an important finding that I notified all the doctors I had seen about this problem. To my great surprise I heard from no one. Not even a thank you. I guess that since they didn't find the solution, they just were not interested.
I hope this discussion helps someone else. Thanks for listening.
-- By rtweaver | Reply | (4) replies | Private Message me
October 29th
2008
11:12 PM
I have been on 20 mg Lipitor for years, and as I also have Rheumatoid Arthritis, all my symptoms have been blamed on that. I have been diagnosed with Fibromyalgia and put on Lyrica because of the muscle aches and depression. My lower back, hurt in a car accident when I was 17 years old, had gotten so much worse that I had 12 steroid shots in my lower spine a couple of years ago. They didn't help my back at all, but my blood sugar went from normal to diabetic levels, and I am now on Byetta to try to lower it.
-- By lancbet | Reply | (5) replies | Private Message meI am a 56 year old woman who was the math specialist in a school district until last December when I had to retire early. My back pain was so severe that I could no longer go from school to school carting materials. I could barely make it from the parking lot to my office. Mentally I was not ready to retire, but physically, I was (and am) a wreck. I have severe muscle pain in my shoulders, sometimes one or the other, but always present. I have tingling in my right hand, especially in my fingertips, and have trouble gripping and drop things easily. In the last few months the pain in my right thigh and calf has gotten unbearable. I thought at first it was sciatica, but I have had sciatica before, and this isn't the same, although there is tingling, burning , but the pins and needles is so deep in the muscles I have just sat and cried, or wanted to scream. I have wished I could just cut my leg off. And...I am on some pretty heavy duty pain killers for the RA: a small dose of prednisone plus Enbrel, Methotrexate, and Vicodin, and this pain is cutting right through all these meds. I get severe headaches, I went off Lipitor for 5 days and seemed a little better, but then went back on, and it came back.
Since I no longer work, I sleep longer, am exhausted ALL the time, have terrible mental fog, am clumsy, cannot stand for more than a minute or so without wanting to scream, cannot walk more than a few yards...just getting to the car is an ordeal. I tell people that I can only shop in shoe stores and furniture stores...the only stores with places to sit down.
I no longer cook or clean, cannot play with my granddaughter, even holding a book to read can be too much, and I love reading. I feel I am just dying bit by bit as I lose parts of myself.
My doctor is really into lowering cholesterol, and has put me on Zetia in the past few months...and it has been in this time that the pain in my leg has gotten unbearable. He wants my cholesterol to be between 50-60, and has said that the Zetia along with the Lipitor will do that. Is this normal or in any way reasonable??? I am having a full blood workup done tomorrow morning, and I want to go off the Lipitor starting the day after.
I came across this web site tonight while looking up Lipitor side effects, and I am shocked. I have so many of these symptoms, and there are so many I had no knowledge of at all. I knew about the muscle aches, but that's all. I hope someone can help me with what supplements and vitamins I should be taking. I started taking CoQ10 a month or so ago. What else should I be taking for my health? I know vitamin C and fish oil, but don't know how much or anything else. Right now I am just stunned with the thought that all of these problems that have left me unhappily retired, exhausted and in constant pain can all be caused from a drug I have been taking to help me be healthier.