Sinulair symptoms and conditions

I am 44 years old and have been taking singulair for about 4 years. 3 months ago I started experiencing crushing chest pain, tingling in my lower limbs, and felt very stressed out. I went to the ER last Thursday and was checked out for angina - the ER doctor told me I was suffering from chronic severe anxiety. I took Ativan for 4 days and felt better, but now the drigs are gone and I again having constant chest pain. In doing some research I found that anxiety can be caused by imbalance in adrenaline, and so started looking online to see if any of the allergy/asthma meds I am taking (adviar, singulair, allegra) can affect adrenaline. That';s when I found this website. Although i find the testimony compelling, I wish more folks would have poted about how their symptoms improved (or didn't) AFTER discontinuing singulair. Also I've noticed many of the stories are about children not adults; many people are taking more than one med for asthma, and most people's symptoms seem to come on right away whereas I have been taking sinulair for years and only recently have anxiety. I will stop singulair tonight and see what happens, but am wondering if anyone has come across further research that correlates singiulair with anxiety? My job life is really peaceful, I am otherwise happy, work can get hectic but that's true of any job, and I am out of ideas as to why suddenly at age 44, when I eat right and exercise - why get anxiety? Thanks for the posts, I'll try to remember to follow up after I am off Singulair for a few weeks.

My son, Wilson, is a bright, easy-going, athletic 12 year old who has a history of asthma and allergies. After several asthmatic episodes from age one year to about four, he was prescribed Singulair. The asthma triggers seemed to be change of season or congestion from a cold, but not from exercise or physical exertion. As I recall, his asthmatic episodes seemed to decrease after he was on 5-10 mg of Singulair, and even more so with each passing year. Over the years, of my three sons, Wilson was the one to catch any virus that came around and missed more school time than both of his brothers combined. Often, he was the only one to get sick from a virus, which never passed to anyone else in the family.
About five years ago, Wilson started complaining of stomach aches. He was tested and was prescribed Prevacid on and off since then with varying success. In the last couple of years, headaches would come and go. He was re-tested for allergies and blood work with no conclusive results. About 2-3 years ago he would complain that he “felt funny…like he needed to do something.” Further conversations revealed that he was expressing anxiety. He’s a good student, has lots of friends at school, and is popular among his sports team mates. Occasionally, a teacher here and there over the last couple of years would note that he did not participate enough in class, or did not appear to be attentive. We thought perhaps he is shy. Still his good behavior, agreeable personality and diligence otherwise earned him good grades overall. He loves school and was very unhappy having to stay home when he was sick.
This past winter, he seemed to catch a virus about once every month and a half which caused him to miss 2-3 days of school. Headaches and stomach aches were common with each illness (sometimes nausea), and sometimes these same symptoms when he was not ill. He would only complain when they were prolonged or significant. Trips to the doctor did not result in anything conclusive. Again, Wilson was only too happy once he returned to school.
He claims that sometimes in school he feels like he’s in a fog and has difficulty concentrating. He gets plenty of sleep and sometimes sleeps up to ten hours during the weekend. We attributed it to adolescence and a busy schedule. He claims that this year is the easiest for him at school, and his social life with his friends is very active. His friends’ parents like him and find him to be an agreeable child. Other adults mistake his sometime mumbling answers and lack of eye contact rude. We concluded that he is just shy. He is the most hyper of his brothers, and has difficulty sitting still and constantly exclaims that he’s bored. We chalked it up to being an active boy. His grades are good in school and we never get complaints about bad behavior.
The last illness started a week ago, and he’s still out of school. The doctor said he had no significant allergy symptoms, other bacterial infections, and his blood work all returned with normal results for white blood counts, liver and kidney functioning and anemia. He can’t return to school because of his constant headaches (which cause pain in different parts of his head), nausea, constant stomach aches, no matter what he eats, and feelings of anxiety, mostly in the evening hours. He’s also complaining of dizziness, leg cramps and other muscle soreness. The notable difference in this illness is the anxiety. My husband and I take turns staying home with him, but if we left him alone for a half an hour at a time while the other was in route picking up a sibling, he became very anxious. In the past, he seemed to enjoy some alone time at home so he could play his computer games. He also becomes easily dizzy with shooting pains in his muscles. The doctor said that viruses can manifest themselves in later stages in the form of sore muscles. However, he was concerned about Wilson’s feelings of anxiety. The anxiety had not been as prevalent in prior illnesses. I finally signed onto the internet reading all the stories about other parent’s observations of their children on Singulair. My husband cautioned me about “internet diagnosing” with symptoms and stories that can be easily taken out of context in hope of self-diagnosis. I’ve always thought that Wilson’s doctors have had good judgment. Both my primary physician and allergist don’t think that Singulair has caused these symptoms, but agreed to take him off as long as we monitored any effect on his asthma.
I don’t know what to think. I want the cause of these problems to be the Singulair, because it’s an easy answer. Today will be the first day he’s off the medication. He probably won’t go to school again tomorrow. We’ll wait and see what happens…

Alright. After observing my daughter for two full weeks after discontinuing Singulair, I have decided to share our story.

Our daughter started taking Singulair last August (2007) to relieve her allergy symptoms. I'd like to add she is an identical twin, whose sister did not need to take the medication, for she had mild allergy symptoms that were easily relieved by taking Allegra. So we clearly have a side-by-side case study where one twin took the Singulair and the other did not. About two weeks later we noticed changes in her behavior and thought it was due to the new school routine and changes, etc. Then she started not eating, and when she did eat, she ate very little. Both girls are in a select soccer league are physically active 4-5 times a week.

Long story short - she stopped eating, lost weight, stopped growing and is now 2.5 inches shorter and 15 lbs. lighter than her identical twin. They are fifth graders, I might add, so 15 lbs is ALOT of weight at their age. She was withdrawn, known to have deep depressive episodes, reacted adversely to everything and, in general, wasn't acting herself since last August. She was not enjoying life at all.

She is usually a quick-witted child, one with a sunny disposition and who interacts with others very well. She is joy packaged in a colorful bottle, ready to share her thoughts with you.

We took her to her pediatrician, a nutritionist, a psychologist and all said she was clearly depressed and that is what led to her changes in eating. No kidding, I thought. But why? What has happened that could have changed her so drastically?

I had never felt so far away from my child as I had with her during this time period. We are a close family and we pride ourselves on being able to freely express how we feel.

My dear mother-in-law saw that the FDA was probing the side-effects of Singulair with children and she mentioned it to me, because she knew that is what my daughter was taking was taking. I never thought about the connection, because I take Singulair. I will add I also take an antidepressant and have made an appointment with my doctor to discuss all of this.

After talking with our pharmacist and getting an exact date as to when she started taking it, I called her pediatrician and discussed it with him. We had not been to him since October, because we took her to everyone else (psychologist, etc), so he had not known exactly what was going on with her mental health. He did, however write in his notes (and told me when I called), "Discontinue Singulair if symptoms persist." Hmmmm. Exactly why I wasn't told this from the beginning, I don't know and am very bothered knowing he wrote that on her chart.

Well, after taking her off it two weeks ago she is now back to her happy, connecting and eating self. People (her father, twin, and I included) noticed a change in three days from stopping use of Singulair.

She has changed IMMENSELY since getting off the Singulair that it has been easy to pinpoint her taking that medication as the reason she has been absolutely miserable for the past SEVEN MONTHS. I thank God it wasn't longer and that she didn't suffer any longer than she already did, but it was a true hell to watch her go through what she did and to watch her decline and to not know (professionals included) what to do. Words diminish how we felt and how we feel now after having her back.

So there you have a side-by-side comparison. One identical twin thrived while NOT taking Singulair and the twin who did take it suffered terribly, physically and mentally, while she was taking it.

The allergy relief she experienced was clearly not worth the internal suffering she endured while taking Singulair. I wish we could turn back time and give her those seven months back.

I have been taking it for about 3-1/2 years. The very first side effect I noticed was insomnia. After doing hunting on Merck, I could not find anything. Finally called the company and they said there were some studies done after the FDA released the drug and insomnia was one side effect. I talked to my doctor, he put me on the kid's dosage to try and help the insomnia. I still had it. So he told me to take it in the morning. The kids dosage wasn't helping as much, so I was put back on the adult dosage. During the first 6 months of being on it I noticed weight gain. I thought it was due to getting older. After seeing other people with weight gain I now believe my 20 plus pounds I have put on and can not get off, no matter what I do is the Singulair. Odd, about 6 months after the start and I was taking the Singulair I wondered if it was that, since I had not changed anything, ate the same, my work keeps me active and NO MATTER WHAT I DID, I JUST KEEP GAINING WEIGHT. Wouldn't you know I just picked up and paid for my new months worth. While it has helped the wheezing, I WILL NOT continue taking it. Also I have had a major problem with forgetfulness, which I NEVER HAD BEFORE SINGULAIR. Also have had problems with being inspired to do things, just don't care anymore.

I am posting again to say to click on SINGULAIR in the news on this page and you will see a story on exactly what this drug is capable of.This story was aired in New york but also went out to other nbc affiliated stations.I am the mom of the boy that died ,and am now planning a trip to Washington DC with a NY.Senator and Congresswoman.We are going to speek to the FDA and request that this drug be reevaluated for safety reasons.If they will consider also a black box warning on the label that would also help parents to know the seriousness of the side effects.If you have questions you can send me a private email and I will do the best I can to direct you in helping in your State.