Sinus cavity symptoms and conditions

First I want to say, after reading several posts, that it seems a lot of you are taking Topamax without food, which may be causing your "spaciness." My doctor suggested always taking it with food, even though it says with or without food, and I only experienced spaciness the few times I took it at bedtime without food. Once I started taking it with breakfast and dinner, that never happened again.

I am a 48 year old woman, prescribed Topamax in September of 08 for migraine associated vertigo without headaches, with facial numbness. The first thing I noticed was I immediately had headaches, which to me indicated it was dehydrating me as that is the only time I get a "normal" headache. So I knew I had to drink a lot of water. Soon after starting Topamax I developed a dry cough that lasted the entire time I was on the med. I did not relate it to the drug at the time, however. It never even occurred to me. After about two months on the drug I started having trouble breathing with extreme dryness in my airways. I was prescribed an albuterol inhaler which did not help. I was then prescribed a corticosteroid inhaler which also did not help. I thought the trouble breathing was from taking Nadolol which I was prescribed for occasional heart fluttering - the neurologist said this was a normal side effect of Topamax. I stopped taking the Nadolol but the trouble breathing continued. I also had more migraines with vertigo and facial numbness than before I started taking the drug. I hoped it would eventually stop and the drug would kick in to help the vertigo, so I stayed on the drug. I had very minor tingling in my feet, but it was tolerable. I became very stressed out, had trouble sleeping, depression, my face started breaking out in November (and still is), I lost interest in everything that I normally enjoy - reading, photography, following politics in the news (sort of an obsession of mine). In December I was so depressed that for the first time in my 11 year career I started canceling appointments and eventually took three weeks off from work to "re-group." In January the neurologist decided that we would increase the dose from 100 mg to 150 mg for one more month, and if it did not get rid of my migraines with vertigo, we would discontinue the drug. The first day on the increased dose I had a killer headache, and I drank 150 ounces of water before it went away. That night I did not have to go to the bathroom during the night, unheard of for me. That's a lot of water to drink and not have to pee. Within two days of increasing the dose, my cough became much worse, and within three days, the breathing became more difficult. Within five days, I was having trouble speaking because my airways felt so dry. I called the doctor the next morning and he said it was not the drug, but if I wanted to, stop taking it. So I went off it cold turkey, per his instructions. I had rebound migraines every day for a week or two and my heart was pounding, sometimes for three or four hours at a time. Eventually the cough and trouble breathing went away, however, I had to continue drinking lots of water or I would notice that I didn't have to urinate, sometimes not at all. Again, unheard of for me. I saw a cardiologist at the neurologist's urging and they said the heart pounding was just anxiety. I disagree, as did another doctor of mine. We both believe it was withdrawal. I have now found out (by getting copies of my medical records) that the neurologist is now attributing all of my side effects from the Topamax to "somatization." In other words, psychosomatic - not a side effect, but just a way of getting medical attention. I am seeing a few people on this board who have also experienced a dry cough and trouble breathing. Can I have the same side effects as other people and have them still be psychosomatic, even though I had no idea those side effects could occur? I don't think so.

I have a theory that Topamax interferes with hormones which causes a lot of the side effects like lack of concentration, memory loss, anxiety, depression, insomnia, acne, and hair loss - all symptoms of peri-menopause and menopause. Ask any woman in her 40's or 50's if she has these symptoms and most of them will say yes. My face has not been this broken out since high school! My hair is falling out at a rapid rate. I won't even bother mentioning these to the neurologist. He'll just say it's not the drug.

I'm very frustrated and not sure what to do at this point. The neurologist has me taking a supplement called Migrelief now, but I think it takes three months to kick in, so I have no relief at this point.

Has anyone else experienced the trouble breathing with dry cough? I don't believe for a moment that it was psychosomatic.

After reading some of these side effects, I'm posting in regard to my 24 year old married daughter. I'm not sure of the time line, but she started Gardasil last year, and I believe she has had 2 doses so far. She had had migraine headaches before, but in the last 6 weeks they have become more frequent and severe. Right now, she has been immobilized with a severe migraine for nearly a week, and none of the usual medications help at all. Her internal medicine specialist is sending her in for a CT scan Monday morning to rule out a brain tumor, or the recurrence of a benign cyst in her sinus cavity like one she had 8 years ago.
She has also had dizziness, nausea, vomiting, among other symptoms. I am very worried about her.

I too have been injected previously with Kenalog shots for allergies. I never had the site indentation that most of you are commenting on. But I can tell you that the menstrual cycles did change considerably. Kenalog is a steroid, and like oral prednisone it is hormonal. It is just like taking birth control pills, you have the irregular or heavy periods, the excessive hunger, hair growth where you don't want it and weight gain. And as far as my allergies are concerned it never worked. I have excessive sinus disease that has been aggravated by living in a dry windy desert climate. After my second sinus surgery in 2 months the holes in my sinus cavity are starting to close up again. So yesterday my doctor tried a new therapy of injecting kenalog right into my sinus cavity. However it was not injected directly. A small piece of spongy foam was placed into my sinus cavity and the medicine was injected into the foam so my nose would absorb it naturally without the tissue being directly injected. I don't know if it will work or not. I have experienced some unpleasant side effects already, higher blood pressure and increased heart rate. Although the heart rate did come down after a few hours. Any kind of steroid causes this problem. I was hospitalized in January with a severe asthma attack and was given steroids thru a I.V. It was the only drug that opened up my lungs, however by the second day my heart temporarily went into v-tach because I was getting too much too often. As soon as it decreased I was fine. So dosage is a major concern. I can tell you from experience that Kenalog last realistically for about a month even though docs tell you it's good for 3. I would not have multiple injections for any reason. But when you are in pain and hurting and you have inflammation in your body, unfortunately steroids of some kind will always be the drug of choice. I have recently started acupuncture and will see if that helps my sinus problems. I have taken up yoga too to help my breathing. I highly recommend these alternatives to drug therapy. I have been on every kind of asthma and allergy drug out there and I do not trust any of them anymore. But ask the doctor lots of questions and refuse the meds if you are not comfortable. if your doctor is herding you in and out of his office or not willing to explain the meds completely then refuse it and go to someone else.

Let me start by giving you some history.

My sister is a 22 year old girl who worked full time and was never seriously ill until this summer.

During the last full week of June my sister started having headaches. She told me that these headaches were like none she had ever had before. Days later she started complaining that her legs and wrists hurt. She said that her legs were so tired and achy she could barely walk up the stairs. At that time I dismissed what she was saying. My sister constantly wears heels and I chalked up the complaint to a pair of shoes that were not yet broken in.

By July 4th, the headaches were so intense that she went to urgent care. The physician she saw in urgent care gave her an antibiotic and sent her on her way. By July 7th, she was having difficulty standing up and walking was almost impossible. My sister started complaining about severe joint pain. Her ankles began to swell and her stomach appeared distended.

On July 8th, my sister went to her primary care physician. I believe he sent her for an x-ray and said that she had a cyst on her sinus cavity which was causing her to have severe headaches. He then gave her another antibiotic and referred her to a rheumatologist never even thinking that these two symptoms may be related.

On July 10th, my sister saw the rheumatoid arthritis doctor her pcp referred her to. He dismissed her complaints saying that she probably has some form of arthritis, but that there are over 800 forms and it would takes months to pin point exactly which one she has. He then gave her a prescription for Celebrex and sent her on her way. She spent the entire week in bed because her joints were so swollen and achy that she could not move. She actually crawled to go to the bathroom.

By the middle of the following week, my sister's stomach began to burn. She contributed it to being a side effect of the Celebrex and stopped taking it on July 21st. We had no idea that the pain was so bad. My sister's last normal meal was on July 22. By the 23 she had no appetite and could not go to the bathroom. On July 24, the stomach pain was so bad that she could not work, or sit, or function. All she did was cry. She went back to her primary care physician who then prescribed her prevacid to help with the so called indigestion. He told her if the pain continues she could call him. On July 25th the pain became unbearable. My sister called her PCP as directed and he told her to go to the ER. Never once did he say he would meet her there! I brought my sister to the ER where they did an x-ray and cat scan of her stomach. They found nothing. At that time my sister had not gone to the bathroom or had anything to eat since the 22nd. The physician in the ER said that she was literally "full of shit" and needed to go home and take a liquid laxative. My sister is only 22 and my parents were away on vacation. We were stupid and didn't know any better and were so happy that they didn't find anything that we accepted his findings and got out of there.

My sister took the liquid laxative prescribed by the ER physician as soon as we got home. We waited anxiously for it to relieve her stomach pain. After many hours the laxative did not work and my sister ended up back in the ER. This time she was screaming in pain. One of the doctors there told her that if she couldn't calm down she needed to leave her ER. My sister did just that. At this point my parents (back from vacation) took my sister home and called Digestive Disease. A doctor there told my mom to give my sister 2 Enemas. He said that should relieve her pain. My mother followed the doctor's orders, but the pain did not stop. Sunday, July 27th my sister was right back in the ER - this time at another hospital. This time my sister was admitted to the hospital for severe stomach pain. After 5 days and numerous tests my sister was discharged. The doctors found nothing in her cat scans, x-rays or ultra sounds. The pain was more manageable (she was on morphine every 2 hours) and they said she was ok to go home.

August 1st my sister had a great day. She was sitting up in bed and seemed to be in good spirits. The following day she couldn't get out of bed. This time it was neck pain. My sister said the pain in the back of her neck was so severe that she could not lift her head up or move it side to side. By August 4th she was admitted to the hospital again. This time we brought her to University Hospital in Syracuse, NY. We were sure to get some answers there...or so we thought. As soon as my sister arrived in the ER they started treating her with antibiotics. They were certain she had an infection. They then told us they would have to do a lumbar puncture to check her spinal fluid for infection. We thought we would finally have an answer to what was wrong with my sister, so we agreed. The spinal fluid came back fine - no infection. At that time they admitted her to the hospital. While at University Hospital my sister was treated by a team of doctors. They tested my sister for lyme disease, west nile, lupus, leukemia etc. They performed a spinal tap, cat scans, x-rays, ultra sounds, blood smears, etc. All of these tests came back negative. The doctors could find nothing abnormal except for an elevated white blood count -22,000 (it was also very high during her last hospitalization), an elevated C reactor and a very high SED rate. After 4 days of numerous tests and pain killers (first morphine, then Dilaudid, then Dilaudid with a fentanol pain patch) they discharged my sister. The head doctor told her that he believed she had viral meningitis and that it would eventually work its way out of her system. By this point my mother and I were skeptical. We did the research and viral meningitis should only last approximately 10 days. Mig had been sick since the last week in June. No one was putting all these symptoms together. On the day of her discharge my sister started getting her stomach pain back. The pain was mostly on the left side of her lower stomach - under her belly button. Again she was told the pain was due to constipation and she should buy some Miralax when she got home.

My sister was home for a mere 2 days before she would be hospitalized again...for the 4th time. Her stomach pain was back and worse then before. My family could not believe this was happening. My sisters spirits were down and the excruciating pain was making her mentally unstable. This time the ER physician recommended a hematologist come in to see my sister. We just wanted answers so we agreed. This hematologist, Dr. R stated that she believed my sister had drug induced lupus. We were shocked as my sister was tested for lupus twice before and both times the test came back negative. Dr. R explained that she believed my sister got drug induced lupus from the Gardasil shot. My entire family was shocked. We had never heard of any severe side effects like this from the Gardasil shot. Dr. R asked my sister for her permission to test her again. My sister agreed and a week later my sister learned that she was positive for drug induced lupus. My entire family was so happy that my sister finally had a diagnosis and could begin treatment. We were told that after a 6 week steroid treatment (Prednisone) my sister would be back to her old self. We were ecstatic!

My sister was home from the hospital and on the steriod treatment for 10 days when things started to go wrong again. The doctors were very concerned with the dosage of Prednisone that my sister was taking (80mg. I'm not sure how many times a day). They cut the dosage down in half over the course of a few days to prevent kidney damage and other side effects. Once the Prednisone was decreased, my sister started getting sick immediately. Her forearms were very weak - she could not put any pressure on them. Her shoulders would tingle and she would get shooting pains down her right arm. One of her doctors believed she was developing fibromyalgia and prescribed her lyrica. Shortly after my sister began taking lyrica she started seeing stars. She had double vision and a migraine that would not go away. My mother called her doctor and told him about this. His answer was for my sister to stop taking the Lyrica. She did immediately.

On August 29th, my sister still had a migraine. This was day 3 without a break. She woke up early Saturday morning and began vomiting every 30 minutes. After a few hours of non stop vomiting my mother called her doctor. His nurse practitioner was on call and she told my mother to take my sister to the ER immediately. My mother went back into my sister's room to tell her they had to go back to the hospital and she found my sister having a seizure. My sister has no history of seizures. My mother called 911 and the ambulance came to bring my sister back to the ER...her 5th hospitalization.

Shortly after arriving at the ER, my sister had another seizure. Immediately after the seizure the ER doctor ordered my sister to have an MRI. My sister had one during her last hospitalization only 2 weeks before. That MRI was normal. This one was not. There are lesions all over my sister's brain. The neurologist told us that he cannot believe she does not have permanent damage. According to him there is no oxygen going to her brain.The neurologist also explained to us that her brain looks as though she has been poisoned. He said that her MRI is very similar to an MRI of a patient who has been poisoned with antifreeze. Later I learned that Gardasil has both aluminum and sodium borate (which is in both rat poison and cockroach killer). However, according to the doctor once your brain looks like my sister's all the poison is out of your body. My sister's team of doctors started debating as to whether this could all still be from the Gardasil shot...my sister's last shot was on 02/22/08. Some believe that the side effects started off as mild, but since they were left untreated for so long they've turned into a serious neurological problem. They told my family the only way to truly know what is going on is to do a brain biopsy.

Yesterday, my sister was transferred to Mass General in Boston. We were hoping for a bigger hospital, better technology, more seasoned doctors. So far my sister has been treated badly. When my mother told the doctors' about the Gardasil shot and the devastating effects it has had on my sister they dismissed it. When my mom asked the doctors to test my sister for heavy metal toxicity they completely ignored her. I fear that she will never get the proper care.

Dosage: 0.4mg / Day for 5 days.
Age: 26
Occupation: Chemist

Physical:
Feels like something is pulling down on my lungs inside of my chest. Sinus blockage. It feels actually like Viagra where there is swelling in the sinus cavity but not due to mucus. Result is a slightly blocked airway in nasal passage. NO EJACULATE, able to orgasm, but nothing comes out. (A good male birth control pill?) Sporadic, short headaches (~2-4 / Day). Shallow breathing, shortness of breath after going up stairs. Feeling weak all day long. Most of these probably due to lower blood pressure.

Mental:
Wanting to sleep more. A small lack of motivation to socialize, but not major. Annoyed / Angered more easily and often. (could be due to NO EJACULATE!!) A little humor there. No, seriously, I am really easy to agitate now. I wouldn't say lower sex drive, but more controlled sex drive. I felt horny most of the time before Flomax, but now only when engaged in sexual activity. (kind of nice actually) Haven't noticed anything about dream alterations.

Side Note:
The ejaculation part scares me a little bit just as others have expressed. As long as it comes back when I am off that is fine. Flomax DOES NOT shrink the prostate, it relaxes the prostate. I can see why this may cause a lack of ejaculate since the prostate in a way, a sperm valve. I feel like this should really be listed in the side effects but I know that masturbation is not part of clinical trials. Interesting though...could it be used as a male birth control pill? The first few days, a small small volume of ejaculate came out. Now, at day 5, dry as a bone.

I've only been taking Singulair for about a week, but the headache started shortly after I began taking it. It's a nasty sharp throbbing across my right temple. My ears have been pretty much constantly plugged and I can feel pressure in my sinus cavity. I went on double doses of zytec and zantac in order to get rid of sinus pressure (headaches, ear aches, and face pain) in the first place...and now it's back. I can breath better, but my asthema wasn't that bad to begin with. For me, the side effects aren't worth it.

I am an average, somewhat healthy 46-year-old woman who is presently taking 50 mgs. daily of Toprol XL for a heart condition - triple arrythmias. For months I have been feeling lethargic and just generally feeling ill with soreness in my ears and throat, and a daily bout with congestion in the mornings that usually clears up midday each day. It finally progressed to the point of fever,chills, muscle aches and pains and general malaise, and I was prescribed Levaquin 500 1xdaily for a diagnosis sinusitus. (Although it's been a few years since I've experienced an acute attack, I do have a history of sinus trouble) Additionally, my facial complexion had become terribly ruddy, blotched and broken out from the underlying sinus infection....

Well, let me just say, that, on my 8th day of Levaquin, perhaps I have noticed a few muscle aches and pains and weakness, as most persons on this website have claimed, but then, in my 46 years of life I have only been on antibiotics 5-6 times and each time I become weak and with muscle aches and pains. Similarly, when one is recovering from anesthesia after surgery, one feels achey and weak. Hello, your body is being subjected to a man-made synthetic to assist your body to achieve its original goal. This most recent goal of mine with levaquin was to rid my body of a sinus infection that had developed an abscess in the sinus cavity. Well, let me add that I have not been able to breathe as clearly and deeply for months, as I have since I started this medication. My lethargy has gone away, and while I still feel the overall feeling of being on a strong antibiotic, I feel extremely improved. I have not developed a red rash. (Perhaps staying in bed resting, and not going in the sun has helped. I do live in sunny Florida) In fact, my ruddy facial complexion has totally improved! I have not had ear ringing, or hallucinations, or an outer body experience, or any other side effect that seems to be popular on this site. Additionally, I experienced not one heart palpitation or heart arrythmia. I agree with the good doctor who recommended on this site that we all take a look at our health history and our symptoms prior to taking the medication and don't blame every symptom on the medication. I am not one to rush to a doctor when I'm feeling a little under the weather, but let me tell you, when I need something to rid my body of bacteria and infection, I thank God for medicenes like Levaquin and the good Doctors who care to really listen to your symptoms and prescribe what you may need.