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Sinusitis symptoms and conditions

Here are side effects posted by other members, that mention sinusitis.
Click on a listing to see the full text of the user's posting, and any replies.
200 Side Effects posted for sinusitis

October 30th
2009
6:08 PM

This is not a new side effect, but the same day I started taking Levaquin for sinusitis, I suspected something was wrong. Within hours, ears were roaring. First night, NO sleep, and that's WITH Ambien CR. Day 2.....depression! Immediate. This is in spite of having a severe depression under control for over a year. Sudden. I really started suspecting Levaquin then, but thought it was a coincidence. Took it this morning. Deep, dark depression. After reading these posts, I knew my suspicions were correct. The depression is getting better after 10-12 hours after the dose. This is really scary stuff. Really scary. Oh, yes, and I had the stomach pains, also. Told my husband it was just hurting like a bruise, not like indigestion or gas. I will report it to my doctor so they will no it's a "no-no" for me....in spite of all the websites that said how safe it was. Glad I found this website. Thank God.

-- By complainer1 | Reply | (3) replies | Private Message me

September 22th
2009
1:02 PM

Wow, am I ever glad I found this site. I'm taking Bactrim for Pouchitis. I thought surely I was going crazy. Just a few days after starting the meds, I ended up in the emergency room because of a headache so severe and fever I thought I had meningitis....I was treated with a Zpack and sent home with a diagnosis of Sinusitis. I had even told the doctor that I just started Bactrim and she said it shouldn't cause these symptoms. Not long after the episode with headaches and fever, I began having joint aches primarily in my legs, but now it's starting up my back. I called the Dr. that prescribed it today, but plan on stopping it whether he recommends to or not. This is crazy...also noticing signs of depression and fatigue...

-- By micheleleewv | Reply | Private Message me

May 10th
2009
3:35 PM

I personally have taken avelox for a sinus infection and experienced severe dizziness and disorientation as well as a very metallic taste and extreme fatigue. My sister was recently given the medication for a kidney infection. She took 5 days worth of a 10 day script. She developed tendinitis in her achillis and has been in constant pain throughout her entire body for over a week now since she discontinued the medication. Each day I keep expecting her to be at least a bit better (she's basically bed ridden from the pain) and yet each day she is not. Can anyone PLEASE tell me, if you have had a similar experience, how long did it take you to recuperate? I would like to be able to give her some hope but also I'd like to get an idea of what we are or might possibly be dealing with.

-- By dazee | Reply | (1) replies | Private Message me

April 15th
2009
6:10 PM

Prescribed Avelox 400 mg for 10 days, to combat sinusitis and lung congestion bordering on pneumonia. Dr. suggested taking it with Mucinex to increase impact on sinuses. Took first pill Monday, 4/13 and didn't have any unexpected side effects. Took 2nd pill Tuesday morning along with Mucinex, pretty much on an empty stomach, with too little liquid. I was having slight headaches, jitters, mild inability to focus, and some buzzing in my ears. After a few hours, I thought it would be safe to take an Aleve to work on the headache. BAD MOVE on my part. Within 10 - 15 minutes, I was violently ill, vomiting everything from an essentially empty stomach. I called my Dr. but he didn't return my call for a few hours. When we talked, I related the episode, and he advised that we should change medications. As we talked, I thought that maybe I had not been careful enough. Maybe there was a magnifier effect from the Avelox, the empty stomach, too little water, the Mucinex, and then adding the Aleve to the mixture. Bottom line, we decided that I'd take it again today, and be careful to avoid the combination issue. So far, it seems to be working. I'm still experiencing the buzzing ears, slight agitation/nervousness, and slight headache, but nothing scary.

There is one thing, though, that also concerns me. I have a recurring inflammation of my right Achilles heel tendon, and this illness or drug treatment brought it on big-time. My right Achilles is extremely painful and is throbbing like crazy. I normally take a Motrin (anti-inflammatory) and it goes away, but I'm not taking a chance with that until I stop the Avelox. My Patient Prescription Information makes a big deal about possible Tendon damage for those over 60, and I'm just about there.

Interesting counter-effect is that instead of not being able to sleep, I slept much better even after the first pill.

-- By njfred | Reply | Private Message me

February 19th
2009
3:52 PM

In December 2008, I was being treated for sinusitis and bronchitis with the antibiotic Avelox. I started taking it in a Thursday and by Saturday I was doubled over in stomach pain. I was also taking a steroid so I wasn't sure which drug was causing my pain so I called the Dr. office and they told me to lower the dose of the steroid. So I followed their instructions and the pain continued. I stopped taking both medications. Two weeks later I had swollen gums around some of my teeth, I thought to myself that I had left over Avelox so I decided to take one before I went to bed. I woke an hour later with anaphylactic shock and a pricey trip to the ER. Before I never had sensitive skin and now my skin has forever changed, thanks to the wonderful drug called, Avelox.

-- By rnursy2002 | Reply | Private Message me

January 10th
2009
2:58 PM

I have severe allergies and cronic sinusitis... like a lot of people on here I have taken all the allergy drugs they make for the past 9 years... Ive had tons of procedures done and sinus surgery last Feb '08. Nothing helps. Ive taken oral steriods many times but recently my new ENT decided to give me a Kenalog shot in Sept. Nothing was explained to me other than it was a steroid. The nurse put it in my left shoulder. I have had all the symptoms people are describing on here except the indent. I have been progressively getting sicker and feeling worse and worse over the past few months. I feel like I could go to bed and just stay there. Now this past Monday he gave me another Kenalog shot in my left shoulder. I heard something on a tv show that it causes depression so I jumped on this site and feel sick about all the messages I have read about people's terrible side effects. I feel like my doctor who I trusted let me down. I am so worried that my shoulder is going to have a big grey dent like everyone is describing on here. I am just so tired of being ill.

-- By lisamartinez13 | Reply | (1) replies | Private Message me

December 26th
2008
12:24 PM

My husband has been taking Singulair for the last two years. It has made a tremendous difference in his frequency of sinusitis in the winter and allergy symptoms during the summer and fall seasons. For at least the last year, he's been having trouble with insomnia, so he is taking Melatonin. This helps but last night something very new happened. We went to bed around 11:15 p.m., then at 12:45 he woke me up and said he was having trouble breathing. He was very agitated and paced around the room, would sit for a few minutes, then get up again, pace and act very agitated. We've been married for 26 years and this is not normal. We almost went to the emergency room but decided to wait. This morning he's tired and very quiet. From reading the other postings, I think that Singulair could be causing the insomnia and now the agitation and depression.

-- By wyogirl | Reply | (1) replies | Private Message me

December 5th
2008
12:27 PM

I started taking Lamictal about a year ago. When I began treatment, I immediately experienced really bad, vivid dreams. They got progressively worse and continue to this day. About 3 months after I began treatment, I began to experience severe hair loss. Several tiny clumps of hair (a hand-full of individual strands) would come out of my hair during washing, and when I combed it after showering. This has occurred every day, and continues. I've lost about 2/3 of my hair and spend more than 5 minutes each day teasing my hair in the bald spots so people can't tell, but the parts in my hair get wider every day. I can't swim in public, go dancing, or go anywhere that might lead to my hair getting sweaty and falling out of shape.

In addition, at the end of every day, I feel like I'm catching the flu. I have a fever of 100, feel achy and have the sniffles. It got so bad that I actually went to the doctor and he prescribed antibiotics for what he said was sinusitis, which is a side affect of Lamictal. I felt better for a few days, then went right back to feeling ill.

I've also experienced periods of intense anxiety and anger. Out of the blue, for absolutely no reason. Constipation is also a problem.

This is not what I signed up for. I'm talking to my doctor next week to get off this crap. There is no good alternative in this category of medication, either. They're all poison with multiple severe and sometimes life-threatening side effects. Screw that. I'd rather be slightly depressed.

-- By jamie244 | Reply | (1) replies | Private Message me

November 23th
2008
11:46 PM

I was prescribed a 21 day dose of Levaquin for a case of severe sinusitis. After Day 1 on Levaquin I had severe back, joint and muscle pains. At first I thought I was coming down with the flu. However the flu never appeared.

After about 5 to 6 days the pain became less severe, however my hips, back and legs continued to hurt. During the nights of doses 15 and 16 I woke to splitting headaches and a burning sensation on the left side of my stomach. After reading others' side effects and the commonality with my side effects I quit taking Levaquin after 16 days.

During the 16 days I was taking Levaquin I was extremely irritable and mildly depressed. At night time I would wake up 3 or 4 times and try to get back to sleep. I have never had insomnia problems in my life until taking Levaquin. My joints and body ached the entire time on Levaquin.

The drug was brutal on my body. I will never take it again. I will seek an alternative antibiotic. I have been off Levaquin for 4 days. Sleeping is going much better, however the muscles in my legs and back still hurt.

-- By rpee | Reply | Private Message me

November 15th
2008
10:42 PM

I'm so glad I found this page. I was prescribed Avelox and Prednisone to treat my sinusitis. I felt nervous the first 3 days but figured it was just the prednisone. After reading this it must have been the Avelox. On day four it was different. It felt like a bad panic attack. Out of body feeling, tingling in the arms with pain in the feet and a general confusion. The feeling of having to run or keep moving around. I was keeping my arms folded because it felt like if I let my hands out they would just start shaking. I'm feeling better now having read this. I feel like calling my doctor and cursing him out. He gave me a coupon with the script which just clarifies how they are being pushed by the drug companies to get this stuff out there. What scares me is the last time I was prescribed antibiotics (6 years ago) for the same thing
at the end of taking them i had developed similar feelings of tingling and confused thought. That led to months of tests for neuro diseases which eventually they told me was from anxiety. The feelings have lingered for the years since but never as bad. Those bad feelings came back again with Avelox which makes me believe it wasn't caused by just anxiety back then and perhaps permanent damage was done. Thanks for reading.

-- By mantecca | Reply | Private Message me

November 9th
2008
7:52 PM

I used to take Atenolol and had side effects. Unfortunately, all doctors know is to push drugs, instead alternatives. I am taking a natural product now with no side effects.

-- By 777 | Reply | (5) replies | Private Message me

November 4th
2008
11:38 AM

My daughter, who is 22 yrs old now, has been on lamictal since January (seizures which came out of the blue after being ill for 2 years) this year. She ended up in the hospital for most of February with vomiting and diarrhea. She was first diagnosed with celiacs, then gastroparesis, all the time the neurologist is telling us it ABSOLUTELY CANNOT BE THE LAMITCAl...now, she has had some twitching and the doctor increased the lamictal from 100mg 2xs daily to 150mg 2xs daily. Well, the diarrhea, which she's already on all kinds of stomach/bowel medicine, never really resolved but now with the increase is worse. I just called and will take her back on Friday, but think we need to find a new doctor, Good luck to everyone. and God help us all.

-- By ktk | Reply | (1) replies | Private Message me

September 18th
2008
11:26 PM

I can't believe I came across this. I have been having the weirdest things going on with me and had no idea they were attributed to my IUD: Mirena. I have had Mirena for a little over a year and actually love it. I stopped having periods all together on it after only having it for 2 months. Never had any cramps, bloating or spotting. I also didn't gain any weight on it. In fact, I lost a lot of weight. However, all my other symptoms are the same as every one else on here. I have an extreme amount of hair loss. I am terrified of the amount of hair I have been losing. I have extremely irritable with my husband and think just don't feel like anything matters anymore. I just feel depressed. Having a two year old doesn't help. :) I also have zero sex drive. I have chronic headaches anyway, but I have had an increase in my headaches. I have had weird low back pain and joint aches in my knees and feet. I have also had a lot congestion and sinusitis, which I read can be a side effect. I have also had some eye and vision problems. Not to mention fatigue, acne, flaky skin, numb fingers and just basically, for the past year, I haven't felt like myself. I am having it removed on Monday and hope that I start to feel like myself again. I am so happy that I started to do some research and discovered this, otherwise I might still be miserable, wondering why. If anyone knows anything about a lawsuit let me know.

-- By wglidden8 | Reply | Private Message me

August 5th
2008
1:41 AM

Hi all,

I had originally posted on 6/29/08, 6 days after having my Mirena removed. I had it for 15 months.

It is now two weeks later. I want to re-iterate that my fatigue is totally gone. My acne has totally gone away. I've not had one bout of dizziness and my appetite has subsided tremendously. The bloating has significantly decreased. The numbness I had in one of my feet has not returned at all. My insomnia has decreased. Eight hours of sleep feels refreshing and enough! I am not exhausted, nor do I have unexplained muscle fatigue just doing simple tasks like folding laundry! I have not had any PMS'y mood swings as I had noted before, which were totally unpredictable on Mirena. (BTW, I was not a moody PMS'r prior!!) I also had a slight case of sinusitis during the last month I had Mirena and never attributed it to it, but perhaps it was now that I've read more of the posts!

I have as yet to go to the lab and get the "thyroid test" the doctor ordered due to the symptoms I reported the day I had it removed, because I am absolutely convinced that Mirena was the cause. I will have it done regardless just to be on the safe side.... but I waited on purpose so my body could get somewhat back to normal.....

I could always "feel" MIrena inside of me when I would lean over to tie my shoes, sometimes during exercise... etc.... and it is so nice to know that thing isn't in me anymore, and I can lean over without fear of poking a hole in my own uterus inadvertently!

So.... I'm still VERY glad I had it removed. I'm feeling more my normal "self" every day. I know it will take my body a while to get back on it's routine but if it took a while for my body to feel that crappy I assume it will take a while to get back on track!!

PS - to those women who said it hurt having the Mirena placed.... I had a hard time with it as well. The removal did hurt, but not as bad as having it placed. The removal is a faster process than placement. I would suggest asking your doctor for a little pain medicine or to take something prior to your appointment to have it removed if you have a low tolerance for pain.

-- By cs12 | Reply | (1) replies | Private Message me

July 31th
2008
11:28 PM

0This is a followup to an email I sent on July 22nd about my mirena experiences. see samsmom on on July 22 for original email.)

I AM SO HAPPY!!!!!

I got in early with my ob/gyn, she had a cancellation!! WOO WOO!!

That was on Monday, July 28th. I cannot tell you how good it felt to get out. No really, when they pulled it out it cramped for a second, but it felt like my body breathed after that. You know what it feels like when you get a kernel of popcorn out off your teeth and how relieved your gums feel after you finally get it out. Well that was the feeling!!

My hand to GOD--by Tuesday, the fogginess I was feeling in my head was gone. I sneezed all night long Monday night and my nose ran like the dickens, but I think that the sinusitis I started to get (never had it before mirena) was actually draining itself out of my head. NO longer did my face feel like there were rocks in it, no longer did I feel like I was walking around in an out of body experience type state. I even felt less mean and moody. These were my instant results.

I am looking forward to weight loss again, this is the biggest I have ever been (excpet pregnancy 143), I am now 130. But I am not as VORACIOUSLY hungry anymore--and the sweets craving is gone.

I forgot to post this, but I also noticed when mirena was in that I was getting facial hair on my chin (like a guy). Not like a beard, but a few stray whiskers here and there that seemed to grow back like weeds. Unfortunately I cannot say that getting rid of mirena stopped the whiskers, because I got them lasered---but that was how bad it was. A lot of unusual hair pattern growth issues in women are linked to hormones. Also what I find interesting is how can the progestine time release in mirena be a one-size-fit-all for women. I mean you have women who are 6 feet and 150 lbs and 4.5 feet women who weigh 90. Does that mean there bodies are equipped to handle the same dosage? HMMMMMM Questions I should have asked.

I hope you consider getting yours removed. I hope that you see results like mine. I feel more in tuned to life, my son and my husband. More energy, less anxious and stressful, the night time nausea and dizziness is totally gone!

Take care!

-- By samsmom | Reply | (1) replies | Private Message me

July 29th
2008
5:00 PM

I was diagnosed with severe sinusitis a week ago, and my doctor prescribed omnicef for me since I was allergic to PENICILLIN. After the first day on Omnicef, I felt fine, perhaps a little better. As days continued to pass, however, I began to get some horrible reactions. They started out mild, and now (after taking it for the seventh day) I have major tongue and gland swelling in addition to a horrible headache and weakness. I've felt close to fainting several times throughout the past several days. I went through a random bout of depression a couple days ago, too, and there was no reason why. I feel more irritable, but I've been attempting to control it. I haven't lashed out wrongly at my loved ones yet, but I've come pretty close. I have some pain in my lower abdomen (where the intestines are located) as well, but only when I walk in a quick manner. No diarrhea, yet, but I think that's because I normally have digestion problems (constipation). Some of the joints in my hands are acting funny. They aren't as strong as usual, and they've been going numb/cold more often, causing their movements to be a little slower/stalled.

I'm seventeen, and when my mom contacted the doctor yesterday, the doctor said that "these aren't allergies/side effects" of this medication, and that I need to continue taking them. So I took them again yesterday (the seventh day), and that's when the swelling of the tongue and glands in my throat took place. When my mom called today and notified the doctor of that issue, the doctor said that..oh, how was that worded... That "it's the first time I've had this reaction" (while on this medication), and that it isn't caused by that medication but from something else. I'm sorry, but I'm not taking any other medications, and I haven't eaten anything strange/new that would cause me these difficulties. It's definitely the medication.

I'm done with this medication. After doing research on it this morning, I've learned that at least ten percent of those allergic to penicillin is also allergic to omnicef, and I'm allergic to penicillin. Why my doctor is being so stubborn about these reactions, I don't know. I guess this is just an example of a doctor who isn't well-educated and sticks ONLY to the side-effects/allergic reactions listed on the prescription bottle. If problems persist, my mom will take me to another doctor. For now, I'm going to stick to the Neti pod and nasal spray to try to rid me of my sinusitis. Maybe it'll work out alright and my problems from this medication will go away quickly. I'm sick of being sick all summer.

-- By sanguinerain | Reply | Private Message me

July 18th
2008
8:38 AM

My son has been taking Singular as well as Advair and Zyrtec and Nasonix for the past 6 months. He is doing so well. He has not had to go to emergency, he has not been sick, and he has not had mood swings. If you look at the prescription information that comes with Singular, you can see what the side effects can be. My recommendation is to take your child off of them if they have a side effect. I contacted my Dr. and Merck is studying only 1 case with a child that had side effects, but they did not say if this child was on other Psych medicine at the same time. The 2 psych meds that have shown a bad interaction with Singular are Phenobarbital and Rifanpin (spelling may be wrong). With all the posts I have read, very few people indicate if they are taking other medications at the same time as Singular. My suggestion is that you consult your Dr. and then send your case to Merck for more studies. If all you are doing is posting on the web, you are not solving this issue with the makers of the medication.

-- By motherbird | Reply | (4) replies | Private Message me

June 6th
2008
2:53 PM

I'm a 31 female. I was diagnosed with bronchitis/sinusitis on 5/28 and was given Biaxin which did not help. I was instructed to return to the doctor if I did not feel better within 2 to 3 days. On Monday 6/2 I returned to the doctors per instructions because I was not feeling better. He switched me to Levaquin 500mg 1 a day. I took Levaquin at 8pm Monday evening. I was unable to sleep that evening so I researched the medication the following morning and saw that Insomnia was a side effect. Starting at 10am today 6/6 I begun severe hip pain in my right hip. I called the doctor and they instructed me to stop taking the medicine for 24 hours and begin treatment again if the pain reduces. After reading this information I'm now reluctant to start "if" the pain subsides.

-- By audprice | Reply | (1) replies | Private Message me

June 1th
2008
9:21 PM

Been a rough last few days for me. It's been 2 months since removal and I felt I was getting better but again once a day I've been feeling 'uneasy' almost to the point of anxiousness but it passes. Have continued to have daily headaches- that hasn't stopped since a week or two before I got it taken out. and the vertigo seems to have returned, just not as bad. Still trying to understand the link between sinusitis and mirena but it's still here. Been very emotional and easily angered. My first cycle did start May 1st so maybe it's about that time. Thoughts?

So frustrated with this whole experience. Just need some reassurance/encouragement. No one in my daily life understands.

-- By mrsnelson78 | Reply | (2) replies | Private Message me

May 21th
2008
1:22 PM

My nephew is 7 and has been on Singulair for probably 4 years. His symptoms developed over time but recently have exploded. He has epilepsy so most of the things that he has experienced has been blamed on that. However, today his doctor took him off singulair and said he believes his symptoms are caused from the drug. He started having head drop seizures, fell out of his desk and cut his face one day. He has also been depressed, had severe anxiety attacks for the past 8 months. Several months ago, he started having such severe nightmares that it is almost impossible to get him to go to bed and go to sleep. Recently he began "seeing dead people" and "monsters" that we trying to kill him even when he was awake. He has also cried many nights with leg cramps and severe stomach pain. I will update this page in two - three weeks to let you know if these problems go away now that we have stopped the singulair.

-- By brenda999 | Reply | (6) replies | Private Message me

May 3th
2008
8:45 AM

I was prescribes Levaquin 500mg for 10 days for sinusitis. On the second day, I woke up with a migraine and took Aleve. The headache accompanied by dizziness lasted 10 days or so. As time has passed, I have pain in my right shoulder and bicep and stiff/swollen joints in the back of my neck. It has been 4 months since I took Levaquin and my symptoms have only gotten worse. I have been on bed rest for a week just after a simple 5 minutes on an elliptical machine. Additional problems along the way have been anemia, my vision got extremely worse with retinal degeneration, anxiety, diarrhea, fatigue, irritability, and numbness in my hands and feet. My doctor says he believes me but mentioned fibromyalgia. My symptoms don't even fit that disease. Friends don't believe me either. I am a pharmaceutical rep. The FDA needs to pull this drug off the market. Why won't they do it? Someone has a connection someone. I am almost 31 years old and I don't know how much more my body can take. I miss my friends, tennis, and even normal daily tasks like opening a car door and sitting for an extended period of time. DO NOT TAKE LEZAQUIN EVER.

-- By ktnowako | Reply | (2) replies | Private Message me

April 23th
2008
3:35 PM

BAD BAD BAD BAD BAD! I took this drug today and thought i was going to die from a heart attack. I began getting palpitations and then it progressed into a full blown panic attack. Thank god I had some Xanax to bring down the side effects. But now I just feel out of it and foggy. I almost called 911, it was that bad. I felt like I couldn't breathe, like there was something standing on my chest. I called my doctor right away who said they had no other samples, that Avelox was the only thing they are really getting right now. That seems really odd to me that a drug like this is on the market with so much negative press and yet its all our physicians have on hand for people like me with no insurance. PLEASE DONT TAKE THIS DRUG, it is terrible...

-- By jasminerosa | Reply | (3) replies | Private Message me

April 20th
2008
12:36 PM

Singulair does interact with the astrocyte in the brain.

The role of the cysLT1 receptor (Singulair blocks this receptor) and the astrocyte in the brain has been studied. For anyone from Merck to say that there are no mechanisms by which Singulair can affect the
brain is ludicrous. If the Chinese researchers are correct, then Singulair very clearly affects the brain. Certainly, we don't know exactly how or when the effect would be good or bad. Under what circumstances would it be beneficial and under what circumstances would it be harmful.

For quite a while, researchers have been hypothesizing about the role of the astrocyte in brain function. If we go to look for theories, we will find them. Here is the theory of Dr. Dale Antanitus. I am no here to promote anyone's theory in particular but just to point out that they exist.

http://www.antanitus.com/hypothesis

We can see that the Chinese researchers have gone forward to look at potential links between the cysLT1 receptor (Singulair receptor) and inflammatory response in the brain. The 2008 study showed a link between the astrocyte and the cysLT1 receptor (Singulair receptor)

1: Glia. 2008 Jan 1;56(1):27-37. Links
Activation of CysLT receptors induces astrocyte proliferation and death after oxygen-glucose deprivation.

Huang XJ, Zhang WP, Li CT, Shi WZ, Fang SH, Lu YB, Chen Z, Wei EQ.
Department of Pharmacology, School of Medicine, Zhejiang University, Hangzhou 310058, People's Republic of China.

We recently found that 5-lipoxygenase (5-LOX) is activated to produce cysteinyl leukotrienes (CysLTs), and CysLTs may cause neuronal injury and astrocytosis through activation of CysLT(1) and CysLT(2) receptors in the brain after focal cerebral ischemia. However, the property of astrocyte responses to in vitro ischemic injury is not clear; whether 5-LOX, CysLTs, and their receptors are also involved in the responses of ischemic astrocytes remains unknown. In the present study, we performed oxygen-glucose deprivation (OGD) followed by recovery to induce ischemic-like injury in the cultured rat astrocytes. We found that 1-h OGD did not injure astrocytes (sub-lethal OGD) but induced astrocyte proliferation 48 and 72 h after recovery; whereas 4-h OGD moderately injured the cells (moderate OGD) and led to death 24-72 h after recovery. Inhibition of phospholipase A(2) and 5-LOX attenuated both the proliferation and death. Sub-lethal and moderate OGD enhanced the production of CysLTs that was inhibited by 5-LOX inhibitors. Sub-lethal OGD increased the expressions of CysLT(1) receptor mRNA and protein, while moderate OGD induced the expression of CysLT(2) receptor mRNA. Exogenously applied leukotriene D(4) (LTD(4)) induced astrocyte proliferation at 1-10 nM and astrocyte death at 100-1,000 nM. The CysLT(1) receptor antagonist montelukast attenuated astrocyte proliferation, the CysLT(2) receptor antagonist BAY cysLT2 reversed astrocyte death, and the dual CysLT receptor antagonist BAY u9773 exhibited both effects. In addition, LTD(4) (100 nM) increased the expression of CysLT(2) receptor mRNA. Thus, in vitro ischemia activates astrocyte 5-LOX to produce CysLTs, and CysLTs result in CysLT(1) receptor-mediated proliferation and CysLT(2) receptor-mediated death. (c) 2007 Wiley-Liss, Inc.

PMID: 17910051

The astrocyte has been studied to see how it functions in the brain. The astrocyte:

1. may perform a role in the physical structuring of the brain
2. may perform a role in providing neurons with nutrients
3. may perform a minor role in the maintenance of the blood brain barrier
4. may perform a role in neurotransmitters
5. may perform a role in the regulation of ion concentration in the extracellular spaces
6. may perform a role in neuronal regulation of blood flood
7. may perform a role in the protection and repair of neurons

TO LIE TO PEOPLE REGARDING THEIR HEALTH IS CRIMINAL AND SHOULD BE PROSECUTED. PEOPLE OUT THERE ARE GETTING SICKER IF THEY ARE EXPERIENCING SIDE EFFECTS BECAUSE MERCK IS LYING. SOME PEOPLE MAY NOT EXPERIENCE SIDE EFFECTS BUT WHY NOT TELL THE TRUTH AND SAY THAT THERE COULD BE SOME PEOPLE WHO HAVE PSYCHIATRIC SIDE EFFECTS BECAUSE THERE IS A PATHWAY FOR THAT TO HAPPEN.

-- By concernedcitizen | Reply | (2) replies | Private Message me

April 19th
2008
7:30 PM

My son has been battling sinusitis for a few months . I didn't know sinusitis could be so bad. His doctor prescribed Levaquin three days ago and I read the side effects and realize it was a risk because my son has seizures.After 2 dosages and sleepless nights with headaches and him not being able to function I've stopped giving it to him.
Thanks for such a great website!
The benefits don't out-weight the risk.

-- By patricia_w | Reply | (3) replies | Private Message me

April 8th
2008
9:09 AM

Update...Today is the 11th day my 7 yr. old son has been Singulair free! He was taking it for "cold induced" asthma. He never had the typical asthma where he needed an inhaler. He got RSV when he was almost 3, then whenever he got a URI it seemed to go straight to his lungs, so the dr. prescribed Singulair and Xopenex (to be used with a nebulizer). I had asked the dr. a few times to take him off Singulair because he seemed to be doing much better and I wanted to see how he would do without it. The dr. would say "oh, let's wait until summer or let's wait until allergy season is over" and kept putting it off. I just had some sort of bad "feeling" about it. Of course, I look back now and know with certainty that his wierd behaviors started around the time he started Singulair. I am relieved now because his erratic behaviors are almost totally gone!!!! When I heard the news I decided to take him off the Singulair immediately. I was nervous because he had a cold and a bad cough, but did it anyway. You know what? He is fine! His cough is almost gone now without the help of Singulair! He is much happier and can actually focus on doing his homework without getting up from his chair until he is done. Before he would get up about 10 times and just couldn't sit still. He has a better attitude about everything now! He is doing great! I hope everyone who was taking this and stopped is doing better! I learned a valuable lesson from all this. I won't put him or my other son on anything until I research it! I will not trust anything anymore, and that in itself is sad, but true. Good luck to all!

-- By laura_seeley | Reply | (2) replies | Private Message me


 

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