Skeletal muscle symptoms and conditions

I was given 40mg Lipitor for elevated cholesterol. I took it until I started having muscle weakness .I am a retired nurse of twenty five years, and knew this symptom was not correct. So I stopped taking the medication and told my doctor of this.He did not protest in any way.My symptoms now include;two torn ligaments, sob,mental deficits, muscle wasting, night sweats, weakness,h/a's, and more. I have not taken Lipitor for two years now. Damage is done.My doctor said it should be out of my system by now. Is this a cover up?

I have been on zocor for over a year, about 8 months ago I began to have pain in my left arm, got and injection and it was better it started again in my left arm , this time there was pain , tingling, numbness, swelling , it got better but it moved to the right arm which is twice as bad, I am often brought to tears from the pain..I sometime describe the pain like shutting your hand in a car door. My Dr keep giving me the same meds.

I have been on lipitor about 4 yrs. I am a runner and keep tract of my times. I have been losing about 4% of my speed each year and have recently had a large amount of muscle fatigue. Today a ran a 940 pace and thought I was not going to make it home. Three years ago my average pace was 805. Could the 20mg dosage be causing this problem?

I have been taking simvastatin since June 28, 2008. I am 44 years old and have always been majorly active with my 17 year old daughter. Recently I have become chronically fatigued so much as to want to go back to bed within 2-3 hours after I get up in the morning, (definitely not me). I have felt spaced out,depressed to the point of wanting to cry all the time, have severe back, hip, knee, leg, and hand pain. I go to pain management for my back and hip problems (past surgery), but the usual pain has been intensified over the last 2 months and I wasn't sure why, until i decided to check out the Simvastatin to see if it has made me put on a few pounds, and boy have my eyes been opened!!!!!!!!! I AM STOPPING THE MEDICATION IMMEDIATELY!!!!!!!!!!!! Thanks to all who have spoken up, I wish I would of checked on this sooner!!!!! I'm calling my Dr. first thing in the morning!!!!!!!!!!!

By exhausted in Canton

I felt it important to share the following information with everyone adversely affected by statins, and hope it permits all to live life more abundantly. Please see the complete article in LifeExtension Magazine: *******/mag2008/feb2008_Alleviating-Congestive-Heart-Failure-With-Coenzyme-Q10_01.htm, as well as, Citizen Petition: Needed - A Change In The Labeling Of All Statin Drugs by Dr. Peter H. Langsjoen, MD, FACC a "Blue Ribbon" Board Certified Cardiologist from Tyler, Texas, who describes in detail the trouble with statins: “All statin drugs block the biosynthesis of both cholesterol and CoQ10, which explains statins’ common side effects of fatigue, muscle pain and muscle weakness, and a worsening of heart failure. When CoQ10 levels are lowered by statin drug therapy, one of the first changes to occur is a weakening of heart muscle function… In 2004, a study published in the American Journal of Cardiology showed that diastolic dysfunction (heart muscle weakness) occurred in 70% of previously normal patients treated with 20 mg a day of Lipitor® for six months. This heart muscle dysfunction was reversible with supplemental CoQ10. Heart failure that develops after years of statin drug therapy can be termed statin cardiomyopathy and may well be playing a role in the epidemic of congestive heart failure in the United States. In an effort to determine the prevalence of adverse effects from using statins, we studied 50 consecutive new patients, all of whom were taking a statin drug at the time of their initial visit. All 50 patients were found to have one or more side effects from statin therapy, so we discontinued their statin drugs and began supplemental CoQ10. Patients were followed for an average of 28 months with the following observations in the prevalence of adverse effects:
• A high prevalence of skeletal muscle pain and weakness at 64% on initial visit was reduced to 6% in follow-up.
• Fatigue decreased from 84% to 16%.
• Shortness of breath went from 58% down to 12%.
• Memory loss was reduced from 8% to 4%.
• Peripheral neuropathy decreased from 10% to 2%.
There were no adverse effects from stopping statin drug therapy with no cases of heart attack or stroke during follow-up. Overall, there was an improvement in heart muscle function on discontinuation of statin therapy and addition of supplemental CoQ10. However, due to powerful propaganda surrounding both cholesterol and statin drug therapy, many patients and physicians are afraid to stop statin therapy…Over the past five years, statins have become more potent, are being prescribed in higher doses, and are being used with reckless abandon in the elderly and in patients with "normal" cholesterol levels. We are in the midst of a CHF (Congestive Heart Failure) epidemic in the US with a dramatic increase over the past decade. Are we causing this epidemic through our zealous use of statins? In large part I think the answer is yes. We are now in a position to witness the unfolding of the greatest medical tragedy of all time - never before in history has the medical establishment knowingly (Merck & Co., Inc. has two 1990 patents combining CoQ10 with statins to prevent CoQ10 depletion and attendant side effects) created a life threatening nutrient deficiency in millions of otherwise healthy people, only to then sit back with arrogance and horrific irresponsibility and watch to see what happens - as I see two to three new statin cardiomyopathies per week in my practice.” Additionally, I have found the following newsletters/medical information helpful:
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I am a 35 yr old male and have been taking lipitor about 7 yrs. I have a genetically high cholesterol and it has been up to 275. On lipitor its around 175. Over the years I have been on this drug I went from being a normal weight and active to pretty much lethargic and sedentary due to lack of energy and gained ~50 lbs. I couldn't sleep. I got random nausea and fogginess in my brain to the point I could not remember how to perform my job. I usually had minor aches and was bloated. the past year everything has gotten much worse. For a year now, I have been getting large rashes on my body that itch severely and no medications have worked to alleviate them. I found out recently from my doctor that I have a genetic marker in my cholesterol that makes me 3 times as likely to have a heart attack. Its a portion of the cholesterol, i think its called LDL-b or something like that. Anyways, My doctor prescribed zetia to help with my cholesterol since the lipitor wasn't doing it alon. I begin feeling very sick when taking the zetia and after a week or two stopped it. The problems didn't end. As long as I remained on the lipitor, the problems seemed to continue. Its like the zetia released a dam of problems. I stopped the lipitor 4 days ago and have noticed that I feel energy coming back to me and the rash is starting to go away, but I ache severely all over. My shoulders, forearms, and legs are so sore and painful that I can't do anything about this except sleep so I don't feel the pain. I am also very weak feeling and I notice stiffness in my fingers and my grip is very weak compared to how it normally is. I have nausea and stomach cramps and constipation. I feel miserable. I notice its worse in the morning and gets a little better towards the afternoon. I typically took my lipitor in the morning. I do not know if there is a relationship here. Please advise on any help you can provide.

KMJ
07-30-08

Please post this on your site for Yasmin side effects.
Thank you for your site. I've been informed my reading it.

I've taken Yasmin for 3 months. Initially had mild nausea taking the pills but solved that by cutting pills in half, and taking half in the morning and the other half with dinner.

However, I haven't been able to solve my SEVERE THIGH and LEG MUSCLE CRAMPS that initially occured daily and particularly nightly. Just like a 'charley horse'. Now I have these only once every 3 days, but it is very annoying and painful to be jumping around on my leg or trying to stretch my thigh, or hamstring, or shin muscle out.

I've read that Yasmin is unique in having a diuretic component to it. Has anyone else experienced these severe skeletal muscle cramps (not uterine or period type cramps)?
If so, have you found any supplements that help, such as Potassium, Calcium, or Magnesium. Please write me at ****** if you have info.

My history is I'm a 50 y/o female with slight anemia from heavy periods placed on Yasmin to control this. I'm a vegetarian who has never had problems in the past taking several different kinds of OCPs including Loestrin. I take no other prescriptions medications or supplements. I have never had skeletal cramps other than maybe once a year prior to taking Yasmin.
Thank you

Thanks to this website, I've learned that my mother is not alone. She has been on Lipitor for 5+ years. She is suffering from rhabdomyolysis and myotosis. Her sympthoms are severe muscle pain, every daily task is 10 tens as difficult. She can not raise her arms over her head to brush her hair. She has difficulty walking, or picking up a kitchen pan. Her doctors have prescribed Prednisone and Azathiprine because she has horrible bruise like blotches all over her body. The doctors seem to think she has arthritis, so they've prescribed- Methotrexate. Sadly, her muscles are severely damaged to the point that she has IV infusions at least twice a month to help get rid of muscle tissue in her bloodstream. You see, the disease (rhabdomyolyis and myotosis) has caused her muscles to disintegrate... and are bodies are made up of muscle- skeletal muscle, heart, lungs, kidneys, esphogus, etc.
She has also experienced hair loss, loss of taste, and like mentioned earlier severe muscle pain, and immobility. I agree with all of you, the pharmaceutical companies need to be held accountable. Thank you for your support.
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